LOCUS AF252293 3801 bp mRNA linear HUM 16-SEP-2002
DEFINITION Homo sapiens partitioning-defective 3 splice variant c (PAR3) mRNA,
complete cds, alternatively spliced.
ACCESSION AF252293
VERSION AF252293.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3801)
AUTHORS Joberty,G., Petersen,C., Gao,L. and Macara,I.G.
TITLE The cell-polarity protein Par6 links Par3 and atypical protein
kinase C to Cdc42
JOURNAL Nat. Cell Biol. 2 (8), 531-539 (2000)
PUBMED 10934474
REFERENCE 2 (bases 1 to 3801)
AUTHORS Gao,L., Macara,I. and Joberty,G.
TITLE Multiple splice variants of Par3 and of a novel related gene,
Par3L, produce proteins with different binding properties
JOURNAL Gene 294 (1-2), 99 (2002)
PUBMED 12234671
REFERENCE 3 (bases 1 to 3801)
AUTHORS Joberty,G.M., Petersen,C.D., Gao,L. and Macara,I.G.
TITLE Direct Submission
JOURNAL Submitted (05-APR-2000) Markey Center for Cell Signaling,
University of Virginia, West Complex, P.O. Box 800577,
Charlottesville, VA 22908-0577, USA
FEATURES Location/Qualifiers
source 1..3801
/db_xref="H-InvDB:HIT000075089"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="kidney"
gene 1..3801
/gene="PAR3"
CDS 1..3801
/gene="PAR3"
/note="multi-PDZ containing protein; PAR3; alternatively
spliced"
/codon_start=1
/product="partitioning-defective 3 splice variant c"
/protein_id="AAF71530.1"
/translation="MKVTVCFGRTRVVVPCGDGHMKVFSLIQQAVTRYRKAIAKDPNY
WIQVHRLEHGDGGILDLDDILCDVADDKDRLVAVFDEQDPHHGGDGTSASSTGTQSPE
IFGSELGTNNVSAFQPYQATSEIEVTPSVLRANMPLHVRRSSDPALIGLSTSVSDSNF
SSEEPSRKNPTRWSTTAGFLKQNTAGSPKTCDRKDEDGTEEDNSRVEPVGHADTGLEH
IPNFSLDDMVKLVEVPNDGGPLGIHVVPFSARGGRTLGLLVKRLEKGGKAEHENLFRE
NDCIVRINDGDLRNRRFEQAQHMFRQAMRTPIIWFHVVPAANKEQYEQLSQSEKNNYY
SSRFSPDSQYIDNRSVNSAGLHTVQRAPRLNHPPEQIDSHSRLPHSAHPSGKPPSAPA
SAPQNVFSTTVSSGYNTKKIGKRLNIQLKKGTEGLGFSITSRDVTIGGSAPIYVKNIL
PRGAAIQDGRLKAGDRLIEVNGVDLVGKSQEEVVSLLRSTKMEGTVSLLVFRQEDAFH
PRELKAEDEDIVLTPDGTREFLTFEVPLNDSGSAGLGVSVKGNRSKENHADLGIFVKS
IINGGAASKDGRLRVNDQLIAVNGESLLGKTNQDAMETLRRSMSTEGNKRGMIQLIVA
RRISKCNELKSPGSPPGPELPIETALDDRERRISHSLYSGIEGLDESPSRNAALSRIM
GKYQLSPTVNMPQDDTVIIEDDRLPVLPPHLSDQSSSSSHDDVGFVTADAGTWAKAAI
SDSADCSLSPDVDPVLAFQREGFGRQIADETKLNTVDDQKAGSPSRDVGPSLGLKKSS
SLESLQTAVAEVTLNGDIPFHRPRPRIIRGRGCNESFRAAIDKSYDKPAVDDDDEGME
TLEEDTEESSRSGRESVSTASDQPSHSLERQMNGNQEKGDKTDRKKDKTGKEKKKDRD
KEKDKMKAKKGMLKGLGDMFRFGKHRKDDKIEKTGKIKIQESFTSEEERIRMKQEQER
IQAKTREFRERQARERDYAEIQDFHRTFGCDDELMYGGVSSYEGSMALNARPQSPREG
HMMDALYAQVKKPRNSKPSPVDSNRSTPSNHDRIQRLRQEFQQAKQDEDVEDRRRTYS
FEQPWPNARPATQSGRHSVSVEVQMQRQRQEERESSQQAQRQYSSLPRQSRKNASSVS
QDSWEQNYSPGEGFQSAKENPRYSSYQGSRNGYLGGHGFNARVMLETQELLRQEQRRK
EQQMKKQPPSEGPSNYDSYKKVQDPSYAPPKGPFRQDVPPSPSQVARLNRLQTPEKGR
PFYS"
misc_feature 682..942
/gene="PAR3"
/note="Region: PDZ domain 1"
misc_feature 1246..1506
/gene="PAR3"
/note="Region: PDZ domain 2"
misc_feature 1594..1851
/gene="PAR3"
/note="Region: PDZ domain 3"
BASE COUNT 1121 a 867 c 1016 g 797 t
ORIGIN
1 atgaaagtga ccgtgtgctt cggacggacc cgggtggtcg tgccgtgcgg ggacggccac
61 atgaaagttt tcagcctcat ccagcaggcg gtgacccgct accggaaggc catcgccaag
121 gatccaaact actggataca ggtgcatcgc ttggaacatg gagatggagg aatactagac
181 cttgatgaca ttctttgtga tgtagcagac gataaagaca gactggtagc agtgtttgat
241 gagcaggatc cacatcacgg aggtgatggc accagtgcca gttccacggg tacccagagc
301 ccagagatat ttggtagtga gcttggcacc aacaatgtct cagcctttca gccttaccaa
361 gcaacaagtg aaattgaggt cacaccttca gtccttcgag caaatatgcc tcttcatgtt
421 cgacgcagta gtgacccagc tctaattggc ctctccactt ctgtcagtga tagtaatttt
481 tcctctgaag agccttcaag gaaaaatccc acacgctggt caacaacagc tggcttcctc
541 aagcagaaca ctgctgggag tcctaaaacc tgcgacagga aggatgagga tgggacagaa
601 gaggataaca gtcgtgttga acctgttgga catgctgaca cgggtttgga gcatataccc
661 aacttttctc tggatgatat ggtaaagctc gtagaagtcc ccaacgatgg agggcctctg
721 ggaatccatg tagtgccttt cagtgctcga ggcggcagaa ccctggggtt attagtaaaa
781 cgattggaga aaggtggtaa agctgaacat gaaaatcttt ttcgtgagaa tgattgcatt
841 gtcaggatta atgatggcga ccttcgaaat agaagatttg aacaagcaca acatatgttt
901 cgccaagcca tgcgtacacc catcatttgg ttccatgtgg ttcctgcagc aaataaagag
961 cagtatgaac aactatccca aagtgagaag aacaattact attcaagccg ttttagccct
1021 gacagccagt atattgacaa caggagtgtg aacagtgcag ggcttcacac ggtgcagaga
1081 gcaccccgac tgaaccaccc gcctgagcag atagactctc actcaagact acctcatagc
1141 gcacacccct cgggaaaacc accatccgct ccagcctcgg cacctcagaa tgtatttagt
1201 acgactgtaa gcagtggtta taacaccaaa aaaataggca agaggcttaa tatccagctt
1261 aagaaaggta cagaaggttt gggattcagc atcacttcca gagatgtaac aataggtggc
1321 tcagctccaa tctatgtgaa aaacattctc ccccgggggg cggccattca ggatggccga
1381 cttaaggcag gagacagact tatagaggta aatggagtag atttagtggg caaatcccaa
1441 gaggaagttg tttcgctgtt gagaagcacc aagatggaag gaactgtgag ccttctggtc
1501 tttcgccagg aagacgcctt ccacccaagg gaactgaaag cagaagatga ggatattgtt
1561 cttacacctg atggcaccag ggaatttctg acatttgaag tcccacttaa tgattcagga
1621 tctgcaggcc ttggtgtcag tgtcaaaggt aaccggtcaa aagagaacca cgcagatttg
1681 ggaatctttg tcaagtccat tattaatgga ggagcagcat ctaaagatgg aaggcttcgg
1741 gtgaatgatc aactgatagc agtaaatgga gaatccctgt tgggcaagac aaaccaagat
1801 gccatggaaa ccctaagaag gtctatgtct actgaaggca ataaacgagg aatgatccag
1861 cttattgttg caaggagaat aagcaagtgc aatgagctga agtcacctgg gagcccccct
1921 ggacctgagc tgcccattga aacagcgttg gatgatagag aacgaagaat ttcccattcc
1981 ctctacagtg ggattgaggg gcttgatgaa tccccaagca gaaatgctgc cctcagtagg
2041 ataatgggta aataccagct gtcccctaca gtgaatatgc cccaagatga cactgtcatt
2101 atagaagatg acaggttgcc agtgcttcct ccacatctct ctgaccagtc ctcttccagc
2161 tcccatgatg atgtggggtt tgtgacggca gatgctggta cttgggccaa ggctgcaatc
2221 agtgattcag ccgactgctc tttgagtcca gatgttgatc cagttcttgc ttttcaacga
2281 gaaggatttg gacgtcagat agctgacgag actaaactca atacagtgga tgaccagaaa
2341 gcaggttctc ccagcagaga tgtgggtcct tccctgggtc tgaagaagtc aagctcgttg
2401 gagagtctgc agaccgcagt tgccgaggtg actttgaatg gggatattcc tttccatcgt
2461 ccacggccgc ggataatcag aggcagggga tgcaatgaga gcttcagagc tgccatcgac
2521 aaatcttatg ataaacccgc ggtagatgat gatgatgagg gcatggagac cttggaagaa
2581 gacacagaag aaagttcaag atcagggaga gagtctgtat ccacagccag tgatcagcct
2641 tcccactctc tggagagaca aatgaatgga aaccaagaga aaggtgataa gactgataga
2701 aaaaaggata aaactggaaa agaaaagaag aaagatagag ataaggagaa ggataaaatg
2761 aaagccaaga agggaatgct gaagggcttg ggagacatgt tcaggtttgg caaacatcga
2821 aaagatgaca agattgagaa aacgggtaaa ataaaaatac aggaatcctt tacatcagaa
2881 gaggagagga tacgaatgaa gcaggagcag gagaggattc aagccaaaac tcgagaattt
2941 agggaacgac aagctcgaga gcgtgactat gctgaaattc aagattttca tcggacattt
3001 ggctgtgatg atgagttaat gtatggggga gtttcttctt atgaaggttc catggctctc
3061 aacgctagac ctcagagccc acgagaaggg catatgatgg atgctttgta tgcccaagtc
3121 aagaagccgc ggaattccaa accctcacct gtagacagta acagatcaac tcctagcaat
3181 catgatcgga tacagcgtct gaggcaagaa tttcagcaag caaagcaaga tgaagatgta
3241 gaagatcgtc ggcggaccta tagttttgag caaccctggc cgaacgcacg gccggcgacg
3301 cagagcgggc gacactcggt gtccgtggag gtgcagatgc agcggcagcg gcaggaggag
3361 cgcgagagct cccagcaggc ccagcgccag tacagctctc tgcctcggca aagcaggaaa
3421 aatgccagct cggtctccca ggactcttgg gagcagaact actcccctgg ggaaggcttc
3481 cagagtgcca aagagaaccc caggtactcc agctaccaag gctccaggaa cggctacctg
3541 ggaggacatg gcttcaacgc cagggtcatg ctggaaactc aggagctcct tcgccaggaa
3601 cagaggcgga aggagcagca gatgaagaag cagcctcctt ccgaggggcc cagcaactat
3661 gactcgtata agaaagtcca ggaccccagt tacgcccctc ccaaggggcc cttccggcaa
3721 gatgtgcccc cctccccttc tcaggttgcg aggctgaaca gacttcagac tcctgagaaa
3781 gggaggccct tctattcctg a
//