LOCUS AF245702 3416 bp mRNA linear HUM 21-MAR-2001
DEFINITION Homo sapiens toll-like receptor 7 (TLR7) mRNA, complete cds.
ACCESSION AF245702
VERSION AF245702.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3416)
AUTHORS Chuang,T.H. and Ulevitch,R.J.
TITLE Cloning and characterization of a sub-family of human toll-like
receptors: hTLR7, hTLR8 and hTLR9
JOURNAL Eur. Cytokine Netw. 11 (3), 372-378 (2000)
PUBMED 11022120
REFERENCE 2 (bases 1 to 3416)
AUTHORS Chuang,T.-H.H. and Ulevitch,R.J.
TITLE Direct Submission
JOURNAL Submitted (15-MAR-2000) Immunology, The Scripps Research Institute,
10550 North Torrey Pines Road, La Jolla, CA 92037, USA
FEATURES Location/Qualifiers
source 1..3416
/db_xref="H-InvDB:HIT000074925"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="X"
/map="Xp22"
/tissue_type="placenta"
gene 1..3416
/gene="TLR7"
CDS 134..3283
/gene="TLR7"
/codon_start=1
/product="toll-like receptor 7"
/protein_id="AAF78035.1"
/translation="MVFPMWTLKRQILILFNIILISKLLGARWFPKTLPCDVTLDVPK
NHVIVDCTDKHLTEIPGGIPTNTTNLTLTINHIPDISPASFHRLDHLVEIDFRCNCVP
IPLGSKNNMCIKRLQIKPRSFSGLTYLKSLYLDGNQLLEIPQGLPPSLQLLSLEANNI
FSIRKENLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFLNLTKLKVLSLKDNNVTA
VPTVLPSTLTELYLYNNMIAKIQEDDFNNLNQLQILDLSGNCPRCYNAPFPCAPCKNN
SPLQIPVNAFDALTELKVLRLHSNSLQHVPPRWFKNINKLQELDLSQNFLAKEIGDAK
FLHFLPSLIQLDLSFNFELQVYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFNLSP
LHNLQNLEVLDLGTNFIKIANLSMFKQFKRLKVIDLSVNKISPSGDSSEVGFCSNART
SVESYEPQVLEQLHYFRYDKYARSCRFKNKEASFMSVNESCYKYGQTLDLSKNSIFFV
KSSDFQHLSFLKCLNLSGNLISQTLNGSEFQPLAELRYLDFSNNRLDLLHSTAFEELH
KLEVLDISSNSHYFQSEGITHMLNFTKNLKVLQKLMMNDNDISSSTSRTMESESLRTL
EFRGNHLDVLWREGDNRYLQLFKNLLKLEELDISKNSLSFLPSGVFDGMPPNLKNLSL
AKNGLKSFSWKKLQCLKNLETLDLSHNQLTTVPERLSNCSRSHKNLILKNNQIRSPTK
YFLQDAFQLRYLDLSSNKIQMIQKTSFPENVLNNLKMLLLHHNRFLCTCDAVWFVWWV
NHTEVTIPYLATDVTCVGPGAHKGQSVISLDLYTCELDLTNLILFSLSISVSLFLMVM
MTASHLYFWDVWYIYHFCKAKIKGYQRLISPDCCYDAFIVYDTKDPAVTEWVLAELVA
KLEDPREKHFNLCLEERDWLPGQPVLENLSQSIQLSKKTVFVMTDKYAKTENFKIAFY
LSHQRLMDEKVDVIILIFLEKPFQKSKFLQLRKRLCGSSVLEWPTNPQAHPYFWQCLK
NALATDNHVAYSQVFKETV"
BASE COUNT 1034 a 762 c 642 g 978 t
ORIGIN
1 tccagatata ggatcactcc atgccatcaa gaaagttgat gctattgggc ccatctcaag
61 ctgatcttgg cacctctcat gctctgctct cttcaaccag acctctacat tccattttgg
121 aagaagacta aaaatggtgt ttccaatgtg gacactgaag agacaaattc ttatcctttt
181 taacataatc ctaatttcca aactccttgg ggctagatgg tttcctaaaa ctctgccctg
241 tgatgtcact ctggatgttc caaagaacca tgtgatcgtg gactgcacag acaagcattt
301 gacagaaatt cctggaggta ttcccacgaa caccacgaac ctcaccctca ccattaacca
361 cataccagac atctccccag cgtcctttca cagactggac catctggtag agatcgattt
421 cagatgcaac tgtgtaccta ttccactggg gtcaaaaaac aacatgtgca tcaagaggct
481 gcagattaaa cccagaagct ttagtggact cacttattta aaatcccttt acctggatgg
541 aaaccagcta ctagagatac cgcagggcct cccgcctagc ttacagcttc tcagccttga
601 ggccaacaac atcttttcca tcagaaaaga gaatctaaca gaactggcca acatagaaat
661 actctacctg ggccaaaact gttattatcg aaatccttgt tatgtttcat attcaataga
721 gaaagatgcc ttcctaaact tgacaaagtt aaaagtgctc tccctgaaag ataacaatgt
781 cacagccgtc cctactgttt tgccatctac tttaacagaa ctatatctct acaacaacat
841 gattgcaaaa atccaagaag atgattttaa taacctcaac caattacaaa ttcttgacct
901 aagtggaaat tgccctcgtt gttataatgc cccatttcct tgtgcgccgt gtaaaaataa
961 ttctccccta cagatccctg taaatgcttt tgatgcgctg acagaattaa aagttttacg
1021 tctacacagt aactctcttc agcatgtgcc cccaagatgg tttaagaaca tcaacaaact
1081 ccaggaactg gatctgtccc aaaacttctt ggccaaagaa attggggatg ctaaatttct
1141 gcattttctc cccagcctca tccaattgga tctgtctttc aattttgaac ttcaggtcta
1201 tcgtgcatct atgaatctat cacaagcatt ttcttcactg aaaagcctga aaattctgcg
1261 gatcagagga tatgtcttta aagagttgaa aagctttaac ctctcgccat tacataatct
1321 tcaaaatctt gaagttcttg atcttggcac taactttata aaaattgcta acctcagcat
1381 gtttaaacaa tttaaaagac tgaaagtcat agatctttca gtgaataaaa tatcaccttc
1441 aggagattca agtgaagttg gcttctgctc aaatgccaga acttctgtag aaagttatga
1501 accccaggtc ctggaacaat tacattattt cagatatgat aagtatgcaa ggagttgcag
1561 attcaaaaac aaagaggctt ctttcatgtc tgttaatgaa agctgctaca agtatgggca
1621 gaccttggat ctaagtaaaa atagtatatt ttttgtcaag tcctctgatt ttcagcatct
1681 ttctttcctc aaatgcctga atctgtcagg aaatctcatt agccaaactc ttaatggcag
1741 tgaattccaa cctttagcag agttgagata tttggacttc tccaacaacc ggcttgattt
1801 actccattca acagcatttg aagagcttca caaactggaa gttctggata taagcagtaa
1861 tagccattat tttcaatcag aaggaattac tcatatgcta aactttacca agaacctaaa
1921 ggttctgcag aaactgatga tgaacgacaa tgacatctct tcctccacca gcaggaccat
1981 ggagagtgag tctcttagaa ctctggaatt cagaggaaat cacttagatg ttttatggag
2041 agaaggtgat aacagatact tacaattatt caagaatctg ctaaaattag aggaattaga
2101 catctctaaa aattccctaa gtttcttgcc ttctggagtt tttgatggta tgcctccaaa
2161 tctaaagaat ctctctttgg ccaaaaatgg gctcaaatct ttcagttgga agaaactcca
2221 gtgtctaaag aacctggaaa ctttggacct cagccacaac caactgacca ctgtccctga
2281 gagattatcc aactgttcca gaagccacaa gaatctgatt cttaagaata atcaaatcag
2341 gagtccgacg aagtattttc tacaagatgc cttccagttg cgatatctgg atctcagctc
2401 aaataaaatc cagatgatcc aaaagaccag cttcccagaa aatgtcctca acaatctgaa
2461 gatgttgctt ttgcatcata atcggtttct gtgcacctgt gatgctgtgt ggtttgtctg
2521 gtgggttaac catacggagg tgactattcc ttacctggcc acagatgtga cttgtgtggg
2581 gccaggagca cacaagggcc aaagtgtgat ctccctggat ctgtacacct gtgagttaga
2641 tctgactaac ctgattctgt tctcactttc catatctgta tctctctttc tcatggtgat
2701 gatgacagca agtcacctct atttctggga tgtgtggtat atttaccatt tctgtaaggc
2761 caagataaag gggtatcagc gtctaatatc accagactgt tgctatgatg cttttattgt
2821 gtatgacact aaagacccag ctgtgaccga gtgggttttg gctgagctgg tggccaaact
2881 ggaagaccca agagagaaac attttaattt atgtctcgag gaaagggact ggttaccagg
2941 gcagccagtt ctggaaaacc tttcccagag catacagctt agcaaaaaga cagtgtttgt
3001 gatgacagac aagtatgcaa agactgaaaa ttttaagata gcattttact tgtcccatca
3061 gaggctcatg gatgaaaaag ttgatgtgat tatcttgata tttcttgaga agccctttca
3121 gaagtccaag ttcctccagc tccggaaaag gctctgtggg agttctgtcc ttgagtggcc
3181 aacaaacccg caagctcacc catacttctg gcagtgtcta aagaacgccc tggccacaga
3241 caatcatgtg gcctatagtc aggtgttcaa ggaaacggtc tagcccttct ttgcaaaaca
3301 caactgccta gtttaccaag gagaggcctg gctgtttaaa ttgttttcat atatatcaca
3361 ccaaaagcgt gttttgaaat tcttcaagaa atgagattgc ccatatttca ggggag
//