LOCUS AF245303 3822 bp mRNA linear HUM 03-MAR-2003
DEFINITION Homo sapiens prominin-2 variant A mRNA, complete cds; alternatively
spliced.
ACCESSION AF245303
VERSION AF245303.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3822)
AUTHORS Fargeas,C.A., Florek,M., Huttner,W.B. and Corbeil,D.
TITLE Characterization of prominin-2, a new member of the prominin family
of pentaspan membrane glycoproteins
JOURNAL J. Biol. Chem. 278 (10), 8586-8596 (2003)
PUBMED 12514187
REFERENCE 2 (bases 1 to 3822)
AUTHORS Fargeas,C.A., Corbeil,D. and Huttner,W.B.
TITLE Identification of a human prominin-related protein sequence
JOURNAL Unpublished
REFERENCE 3 (bases 1 to 3822)
AUTHORS Fargeas,C.A., Corbeil,D. and Huttner,W.B.
TITLE Direct Submission
JOURNAL Submitted (14-MAR-2000) Neurobiology, University of Heidelberg and
Max-Planck-Institute of Molecular Cell Biology and Genetics, INF
364, Heidelberg 69120, Germany
FEATURES Location/Qualifiers
source 1..3822
/db_xref="H-InvDB:HIT000074896"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="2"
/tissue_type="kidney"
/dev_stage="adult"
/note="pooled from 8 male and female Caucasians, ages
24-55, who died from trauma"
CDS 134..2638
/note="from variant A transcript"
/codon_start=1
/product="prominin-2 variant A"
/protein_id="AAM10541.1"
/translation="MKHTLALLAPLLGLGLGLALSQLAAGATDCKFLGPAEHLTFTPA
ARARWLAPRVRAPGLLDSLYGTVRRFLSVVQLNPFPSELVKALLNELASVKVNEVVRY
EAGYVVCAVIAGLYLLLVPTAGLCFCCCRCHRRCGGRVKTEHKALACERAALMVFLLL
TTLLLLIGVVCAFVTNQRTHEQMGPSIEAMPETLLSLWGLVSDVPQELQAVAQQFSLP
QEQVSEELDGVGVSIGSAIHTQLRSSVYPLLAAVGSLGQVLQVSVHHLQTLNATVVEL
QAGQQDLEPAIREHRDRLLELLQEARCQGDCAGALSWARTLELGADFSQVPSVDHVLH
QLKGVPEANFSSMVQEENSTFNALPALAAMQTSSVVQELKKAVAQQPEGVRTLAEGFP
GLEAASRWAQALQEVEESSRPYLQEVQRYETYRWIVGCVLCSVVLFVVLCNLLGLNLG
IWGLSARDDPSHPEAKGEAGARFLMAGVGLSFLFAAPLILLVFATFLVGGNVQTLVCR
SWENGELFEFADTPGNLPPSMNLSQLLGLRKNISIHQAYQQCKEGAALWTVLQLNDSY
DLEEHLDINQYTNKLRQELQSLKVDTQSLDLLSSAARRDLEALQSSGLQRIHYPDFLV
QIQRPVVKTSMEQLAQELQGLAQAQDNSVLGQRLQEEAQGLRNLHQEKVVPQQSLVAK
LNLSVRALESSAPNLQLETSDVLANVTYLKGELPAWAARILRNVSECFLAREMGYFSQ
YVAWVREEVTQRIATCQPLSGALDNSRVILCDMMADPWNAFWFCLAWCTFFLIPSIIF
AVKTSKYFRPIRKRLSSTSSEETQLFHIPRVTSLKL"
BASE COUNT 741 a 1081 c 1147 g 853 t
ORIGIN
1 gctcagggac ccaaacctgt cgggcaggtt ttgagagctg tggagagagg gacagaggct
61 ggagaaggat gtatggcctg ccctgggctt gtctgttccc tcctgagcct gagcccctta
121 ccttcctgac cccatgaagc acacactggc tctgctggct cccctgctgg gcctgggcct
181 ggggctggcc ctgagtcagc tggctgcagg ggccacagac tgcaagttcc ttggcccggc
241 agagcacctg acattcaccc cagcagccag ggcccggtgg ctggcccctc gagttcgtgc
301 gccaggactc ctggactccc tctatggcac cgtgcgccgc ttcctctcgg tggtgcagct
361 caatcctttc ccttcagagt tggtaaaggc cctactgaat gagctggcct ccgtgaaggt
421 gaatgaggtg gtgcggtacg aggcgggcta cgtggtatgc gctgtgatcg cgggcctcta
481 cctgctgctg gtgcccactg ccgggctttg cttctgctgc tgccgctgcc accggcgctg
541 cgggggacga gtgaagacag agcacaaggc gctggcctgt gagcgcgcgg ccctcatggt
601 cttcctgctg ctgaccaccc tcttgctgct gattggtgtg gtctgtgcct ttgtcaccaa
661 ccagcgcacg catgaacaga tgggccccag catcgaggcc atgcctgaga ccctgctcag
721 cctctggggc ctggtctctg atgtccccca agagctgcag gccgtggcac agcaattctc
781 cctgccccag gagcaagtct cagaggagct ggatggtgtt ggtgtgagca ttgggagcgc
841 gatccacact cagctcagga gctccgtgta ccccttgctg gcggccgtgg gcagtttggg
901 ccaggtcctg caggtctccg tgcaccacct gcaaaccttg aatgctacag tggtagagct
961 gcaggccggg cagcaggacc tggagccagc catccgggaa caccgggacc gcctccttga
1021 gctgctgcag gaggccaggt gccagggaga ttgtgcaggg gccctgagct gggcccgcac
1081 cctggagctg ggtgctgact tcagccaggt gccctctgtg gaccatgtcc tgcaccagct
1141 aaaaggtgtc cccgaggcca acttctccag catggtccag gaggagaaca gcaccttcaa
1201 cgcccttcca gccctggctg ccatgcagac atccagcgtg gtgcaagagc tgaagaaggc
1261 agtggcccag cagccggaag gggtgaggac actggctgaa gggttcccgg gcttggaggc
1321 agcttcccgc tgggcccagg cactgcagga ggtggaggag agcagccgcc cctacctgca
1381 ggaggtgcag agatacgaga cctacaggtg gatcgtgggc tgcgtgctgt gctccgtggt
1441 cctattcgtg gtgctctgca acctgctggg cctcaatctg ggcatctggg gcctgtctgc
1501 cagggacgac cccagccacc cagaagccaa gggcgaggct ggagcccgct tcctcatggc
1561 aggtgtgggc ctcagcttcc tctttgctgc acccctcatc ctcctggtgt tcgccacctt
1621 cctggtgggt ggcaacgtgc agacgctggt gtgccggagc tgggagaacg gcgagctctt
1681 tgagtttgca gacaccccag ggaacctgcc cccgtccatg aacctgtcgc aacttcttgg
1741 cctgaggaag aacatcagca tccaccaagc ctatcagcag tgcaaggaag gggcagcgct
1801 ctggacagtc ctgcagctca acgactccta cgacctggag gagcacctgg atatcaacca
1861 gtataccaac aagctacggc aggagttgca gagcctgaaa gtagacacac agagcctgga
1921 cctgctgagc tcagccgccc gccgggacct ggaggccctg cagagcagtg ggcttcagcg
1981 catccactac cccgacttcc tcgttcagat ccagaggccc gtggtgaaga ccagcatgga
2041 gcagctggcc caggagctgc aaggactggc ccaggcccaa gacaattctg tgctggggca
2101 gcggctgcag gaggaggccc aaggactcag aaaccttcac caggagaagg tcgtccccca
2161 gcagagcctt gtggcaaagc tcaacctcag cgtcagggcc ctggagtcct ctgccccgaa
2221 tctccagctg gagacctcag atgtcctagc caatgtcacc tacctgaaag gagagctgcc
2281 tgcctgggca gccaggatcc tgaggaatgt gagtgagtgt ttcctggccc gggagatggg
2341 ctacttctcc cagtacgtgg cctgggtgag agaggaggtg actcagcgca ttgccacctg
2401 ccagcccctc tccggagccc tggacaacag ccgtgtgatc ctgtgtgaca tgatggctga
2461 cccctggaat gccttctggt tctgcctggc atggtgcacc ttcttcctga tccccagcat
2521 catctttgcc gtcaagacct ccaaatactt ccgtcctatc cggaaacgcc tcagctccac
2581 cagctctgag gagactcagc tcttccacat cccccgggtt acctccctga agctgtaggg
2641 ccttgtggga gtgatctggt ggccagaaca ggattttgca cggccccttt tatcctgcgc
2701 atgtggccta gggtcatccc cagcccatcc ctgtgtcagc cctgagtgct ggacactgcg
2761 ttccagaaat gaggaagagg agagagaaga gatggacaga cctcagatcc attaaagtgt
2821 tctcacttcc ctgagacttg gttctgggtc cttaaaacca ggtttcctag gctgggaccc
2881 tgtacatagt tggtgtttaa tgagtgttta tggagaggag agttctaagg tcacctctgg
2941 ctgcaggcat ccagggatta ttccagcaat ctgcaggtag ggagtgggtc ccagcctggg
3001 agcctgctgt caggagcagg cagacctgga ctcacagcct ggctgtgatg cttgttcgct
3061 cagcttctcc atttatgaga tggggagaat agtcacagcc tcctcaaagg gttgtgaaaa
3121 tcaaatgtga taatttgtgg aaagccctta gcagtggcct ggcacaaaac aaatgctcag
3181 tggatggaag ctgcctatta ttattgtcgt tgttgttgtt tgccatgact gctctgggcc
3241 gggggtagag ctagcatccg ggcatgtacg agggaagagg gaggcaggcc tctattcaaa
3301 ggcagaaatt cctttaagat tgtggtctgc tgggtttcag ggagtgtctg tgttgtttgt
3361 ttttgtttgt ttgtttgttt tgagacgggg tctcgctctg tcacccaggc tggagtgtag
3421 tggtgcagtc ttggctcact gcagcctcca cctcctgggc tcaagcgatt ctcatgcctc
3481 agcctcccga gtagctggga ctgcaggtgt gtgccactat gcctggctaa tttttgtgtt
3541 ttttgtagag acggggtttt gccatgttgc ccaggctgga agtgtctatg tttaactgca
3601 tcttataaac cagcaacaag ttttctactg ggaattagaa tggtgcatac acaatgtatt
3661 attatcactg tcagatgagc atgcttgaat gtagcatgac tgcctctttt tgcttttcct
3721 agaggttttt tttttgcttg ttactcatct gttgacctac ctgggggaag tagcaccctt
3781 gcatttcaaa aataaaattg atggcattac aaatggaata ga
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