LOCUS AF244135 2032 bp mRNA linear HUM 17-JUL-2002
DEFINITION Homo sapiens hepatocellular carcinoma-associated antigen 66 (HCA66)
mRNA, complete cds.
ACCESSION AF244135
VERSION AF244135.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2032)
AUTHORS Wang,Y., Han,K.J., Pang,X.W., Vaughan,H.A., Qu,W., Dong,X.Y.,
Peng,J.R., Zhao,H.T., Rui,J.A., Leng,X.S., Cebon,J., Burgess,A.W.
and Chen,W.F.
TITLE Large scale identification of human hepatocellular
carcinoma-associated antigens by autoantibodies
JOURNAL J. Immunol. 169 (2), 1102-1109 (2002)
PUBMED 12097419
REFERENCE 2 (bases 1 to 2032)
AUTHORS Han,K., Wang,Y., Qu,W., Pang,X., Zhang,H. and Chen,W.
TITLE Cloning and characterization of novel genes related to human
hepatocellular carcinoma
JOURNAL Unpublished
REFERENCE 3 (bases 1 to 2032)
AUTHORS Han,K., Wang,Y., Qu,W., Pang,X., Zhang,H. and Chen,W.
TITLE Direct Submission
JOURNAL Submitted (10-MAR-2000) Department of Immunology, Beijing Medical
University, 38 Xueyuan Road, Beijing 100083, P.R.China
FEATURES Location/Qualifiers
source 1..2032
/db_xref="H-InvDB:HIT000074873"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="17"
/tissue_type="hepatocellular carcinoma"
gene 1..2032
/gene="HCA66"
CDS 43..1836
/gene="HCA66"
/codon_start=1
/product="hepatocellular carcinoma-associated antigen 66"
/protein_id="AAF66244.1"
/translation="MAEIIQERIEDRLPELEQLERIGLFSHAEIKAIIKKASDLEYKI
QRRTLFKEDFINYVQYEINLLELIRRRRTRIGYSFKKDEIENSIVHRVQGVFQRASAK
WKDDVQLWLSYVAFCKKWATKTRLSKVFSAMLAIHSNKPALWIMAAKWEMEDRLSSES
ARQLFLRALRFHPECPKLYKEYFRMELMHAEKLRKEKEEFEKASMDVENPDYSEEILK
GELAWIIYKNSVSIIKGAEFHVSLLSIAQLFDFAKDLQKEIYDDLQALHTDDPLTWDY
VARRELEIESQTEEQPTTKQAKAVEVGRKEERCCAVYEEAVKTLPTEAMWKCYITFCL
ERFTKKSNSGFLRGKRLERTMTVFRKAHELKLLSECQYKQLSVSLLCYNFLREALEVA
VAGTELFRDSGTMWQLKLQVLIESKSPDIAMLFEEAFVHLKPQVCLPLWISWAEWSEG
AKSQEDTEAVFKKALLAVIGADSVTLKNKYLDWAYRSGGYKKARAVFKSLQESRPFSV
DFFRKMIQFEKEQESCNMANIREYYERALREFGSADSDLWMDYMKEELNHPLGRPENC
GQIYWRAMKMLQGESAEAFVAKHAMHQTGHL"
BASE COUNT 624 a 359 c 518 g 531 t
ORIGIN
1 gctgttgaga agctacccgc ggggttgtag acctcggacc tcatggcaga gataattcag
61 gaacgcatag aagatcggct cccggaattg gaacagctgg agcgcattgg actgttcagt
121 catgcggaga ttaaggctat cattaagaag gcttccgatc tagagtacaa aatccagaga
181 agaacccttt tcaaggaaga ctttatcaat tatgttcaat atgaaattaa tcttttggag
241 ctgatccgga gaagaagaac acgcattgga tattcattta agaaggatga gattgagaat
301 tctattgtac accgggtaca aggtgttttc cagcgtgcct cagcaaaatg gaaagacgat
361 gttcaacttt ggctctccta tgtggctttt tgtaagaagt gggctactaa aactcgactt
421 agcaaggtat tctctgccat gttggcgatt cattccaaca aaccagcttt gtggattatg
481 gcagccaaat gggaaatgga agatcgattg tcttcagaaa gcgcaaggca actatttctt
541 cgcgcactgc gctttcatcc agagtgccca aaactttata aagaatactt taggatggag
601 ctgatgcatg ctgaaaaact gaggaaggag aaggaagaat ttgaaaaagc cagtatggat
661 gtggagaatc ctgattattc tgaagaaatc cttaagggcg agttggcatg gatcatctac
721 aaaaattctg taagcataat taaaggtgca gaatttcacg tgtcactgct ttcgattgca
781 cagctatttg actttgccaa agatctacaa aaagagattt atgatgacct tcaggctcta
841 cacacagatg atcctctcac ttgggattat gtggcaaggc gagaattaga gattgagtca
901 cagacagaag agcagcctac aacgaaacaa gccaaagcag tggaggtcgg ccggaaggag
961 gagaggtgct gtgctgtgta tgaagaggca gtgaagactc tgccaacaga ggccatgtgg
1021 aagtgttaca tcaccttttg cttggaaaga tttactaaga agtcaaatag tgggttcctt
1081 agagggaaga ggttggaaag aaccatgact gtattcagga aggcacatga actgaagctt
1141 ctgtcagaat gccaatacaa gcagttgagt gtttcgttgc tgtgttataa cttcctgagg
1201 gaagctctgg aagtggcagt agctggaact gaattgttta gagactctgg gacaatgtgg
1261 cagctgaagc tgcaggtgct gatcgagtca aagagccctg acatagccat gctttttgaa
1321 gaagcctttg tgcacctgaa accccaggtt tgtctgccat tgtggatttc ctgggcagag
1381 tggagtgaag gtgccaaaag ccaagaagac actgaggcag tctttaagaa agctctctta
1441 gctgtcatag gtgccgactc agtaaccctg aagaataagt acctggattg ggcttatcga
1501 agtggtggct acaaaaaggc cagagctgtg tttaaaagtt tacaggagag ccgaccattt
1561 tcagttgact ttttcaggaa aatgattcag tttgaaaagg agcaagaatc ctgcaatatg
1621 gcgaacataa gagaatatta tgagagagct ttgagagagt ttggatccgc agattctgat
1681 ctttggatgg attatatgaa agaagaattg aaccaccccc ttggtagacc tgagaactgt
1741 ggacagatct actggcgagc gatgaaaatg ttgcagggag agtcagcaga ggcatttgta
1801 gctaaacatg ctatgcatca gactggccat ttatgaagat gaagaatacc gtccgctttg
1861 tgaaatagta ttgcaagcca gccccgtggg caaatttgta ttgagtccat ctgtaatttg
1921 ctcagtgatg gcagacaaga tggctgtctg gttttgagac acacacttta attttatgtt
1981 aacttgttaa atctttttaa aaattaaaaa atttttatga ttgaaaaaaa aa
//