LOCUS AF242222 1846 bp mRNA linear HUM 14-JAN-2001
DEFINITION Homo sapiens TPEF (TPEF) mRNA, complete cds.
ACCESSION AF242222
VERSION AF242222.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1846)
AUTHORS Liang,G., Robertson,K.D., Talmadge,C., Sumegi,J. and Jones,P.A.
TITLE The gene for a novel transmembrane protein containing epidermal
growth factor and follistatin domains is frequently hypermethylated
in human tumor cells
JOURNAL Cancer Res. 60 (17), 4907-4912 (2000)
PUBMED 10987305
REFERENCE 2 (bases 1 to 1846)
AUTHORS Liang,G. and Jones,P.A.
TITLE Direct Submission
JOURNAL Submitted (06-MAR-2000) Urology, USC/Norris Comprehensive Cancer
Center, 1441 Eastlake Ave, Los Angeles, CA 90033, USA
FEATURES Location/Qualifiers
source 1..1846
/db_xref="H-InvDB:HIT000074836"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="2"
/map="2q33"
/tissue_type="brain"
/dev_stage="infant"
gene 1..1846
/gene="TPEF"
CDS 410..1534
/gene="TPEF"
/note="transmembrane protein; contains epidermal growth
factor and follistating domains"
/codon_start=1
/product="TPEF"
/protein_id="AAG49452.1"
/translation="MVLWESPRQCSSWTLCEGFCWLLLLPVMLLIVARPVKLAAFPTS
LSDCQTPTGWNCSGYDDRENDLFLCDTNTCKFDGECLRIGDTVTCVCQFKCNNDYVPV
CGSNGESYQNECYLRQAACKQQSEILVVSEGSCATDAGSGSGDGVHEGSGETSQKETS
TCDICQFGAECDEDAEDVWCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEK
IEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHG
KCEHSINMQEPSCRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVI
CVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI"
BASE COUNT 484 a 443 c 454 g 465 t
ORIGIN
1 agagggatgc gggcggcaga gctcgagagg cggctgccgg gctgcggggc gccttgactc
61 tccctccacc ctgcctcctc gggctccact cgtctgcccc tggactcccg tctcctcctg
121 tcctccggct tcccagagct ccctccttat ggcagcagct tcccgcgtct ccggcgcagc
181 ttctcagcgg acgaccctct cgctccgggg ctgagcccag tccctggatg ttgctgaaac
241 tctcgagatc atgcgcgggt ttggctgctg cttccccgcc gggtgccact gccaccgccg
301 ccgcctctgc tgccgccgtc cgcgggatgc tcagtagccc gctgcccggc ccccgcgatc
361 ctgtgttcct cggaagccgt ttgctgctgc agagttgcac gaactagtca tggtgctgtg
421 ggagtccccg cggcagtgca gcagctggac actttgcgag ggcttttgct ggctgctgct
481 gctgcccgtc atgctactca tcgtagcccg cccggtgaag ctcgctgctt tccctacctc
541 cttaagtgac tgccaaacgc ccaccggctg gaattgctct ggttatgatg acagagaaaa
601 tgatctcttc ctctgtgaca ccaacacctg taaatttgat ggggaatgtt taagaattgg
661 agacactgtg acttgcgtct gtcagttcaa gtgcaacaat gactatgtgc ctgtgtgtgg
721 ctccaatggg gagagctacc agaatgagtg ttacctgcga caggctgcat gcaaacagca
781 gagtgagata cttgtggtgt cagaaggatc atgtgccaca gatgcaggat caggatctgg
841 agatggagtc catgaaggct ctggagaaac tagtcaaaag gagacatcca cctgtgatat
901 ttgccagttt ggtgcagaat gtgacgaaga tgccgaggat gtctggtgtg tgtgtaatat
961 tgactgttct caaaccaact tcaatcccct ctgcgcttct gatgggaaat cttatgataa
1021 tgcatgccaa atcaaagaag catcgtgtca gaaacaggag aaaattgaag tcatgtcttt
1081 gggtcgatgt caagataaca caactacaac tactaagtct gaagatgggc attatgcaag
1141 aacagattat gcagagaatg ctaacaaatt agaagaaagt gccagagaac accacatacc
1201 ttgtccggaa cattacaatg gcttctgcat gcatgggaag tgtgagcatt ctatcaatat
1261 gcaggagcca tcttgcaggt gtgatgctgg ttatactgga caacactgtg aaaaaaagga
1321 ctacagtgtt ctatacgttg ttcccggtcc tgtacgattt cagtatgtct taatcgcagc
1381 tgtgattgga acaattcaga ttgctgtcat ctgtgtggtg gtcctctgca tcacaaggaa
1441 atgccccaga agcaacagaa ttcacagaca gaagcaaaat acagggcact acagttcaga
1501 caatacaaca agagcgtcca cgaggttaat ctaaagggag catgtttcac agtggctgga
1561 ctaccgagag cttggactac acaatacagt attatagaca aaagaataag acaagagatc
1621 tacacatgtt gccttgcatt tgtggtaatc tacaccaatg aaaacatgta ctacagctat
1681 atttgattat gtatggatat atttgaaata gtatacattg tcttgatgtt ttttctgtaa
1741 tgtaaataaa ctatttatat cacacaatat agttttttct ttcccatgta tttgttatat
1801 ataataaata ctcagtgatg agaaaaaaaa aaaaaaaaaa aaaaaa
//