LOCUS AF240635 5205 bp mRNA linear HUM 06-DEC-2000
DEFINITION Homo sapiens vascular endothelial cadherin 2 mRNA, complete cds.
ACCESSION AF240635
VERSION AF240635.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5205)
AUTHORS Ludwig,D., Lorenz,J., Dejana,E., Bohlen,P., Hicklin,D.J., Witte,L.
and Pytowski,B.
TITLE cDNA cloning, chromosomal mapping, and expression analysis of human
VE-Cadherin-2
JOURNAL Mamm. Genome 11 (11), 1030-1033 (2000)
PUBMED 11063261
REFERENCE 2 (bases 1 to 5205)
AUTHORS Ludwig,D., Lorenz,J. and Pytowski,B.
TITLE Direct Submission
JOURNAL Submitted (01-MAR-2000) Molecular and Cellular Biology, ImClone
Systems, Inc., 180 Varick Street, New York, NY 10014, USA
FEATURES Location/Qualifiers
source 1..5205
/db_xref="H-InvDB:HIT000074814"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="5"
/map="5q31"
/clone="740.15.9; JB 161.2.1"
CDS 1212..4766
/note="VE-cadherin-2; protocadherin; similar to GenBank
Accession Number Y08715"
/codon_start=1
/product="vascular endothelial cadherin 2"
/protein_id="AAF73962.1"
/translation="MMQLLQLLLGLLGPGGYLFLLGDCQEVTTLTVKYQVSEEVPSGT
VIGKLSQELGREERRRQAGAAFQVLQLPQALPIQVDSEEGLLSTGRRLDREQLCRQWD
PCLVSFDVLATGDLALIHVEIQVLDINDHQPRFPKGEQELEISESASLRTRIPLDRAL
DPDTGPNTLHTYTLSPSEHFALDVIVGPDETKHAELIVVKELDREIHSFFDLVLTAYD
NGNPPKSGTSLVKVNVLDSNDNSPAFAESSLALEIQEDAAPGTLLIKLTATDPDQGPN
GEVEFFLSKHMPPEVLDTFSIDAKTGQVILRRPLDYEKNPAYEVDVQARDLGPNPIPA
HCKVLIKVLDVNDNIPSIHVTWASQPSLVSEALPKDSFIALVMADDLDSGHNGLVHCW
LSQELGHFRLKRTNGNTYMLLTNATLDREQWPKYTLTLLAQDQGLQPLSAKKQLSIQI
SDINDNAPVFEKSRYEVSTRENNLPSLHLITIKAHDADLGINGKVSYRIQDSPVAHLV
AIDSNTGEVTAQRSLNYEEMAGFEFQVIAEDSGQPMLASSVSVWVSLLDANDNAPEVV
QPVLSDGKASLSVLVNASTGHLLVPIETPNGLGPAGTDTPPLATHSSRPFLLTTIVAR
DADSGANGEPLYSIRSGNEAHLFILNPHTGQLFVNVTNASSLIGSEWELEIVVEDQGS
PPLQTRALLRVMFVTSVDHLRDSARKPGALSMSMLTVICLAVLLGIFGLILALFMSIC
RTEKKDNRAYNCREAESTYRQQPKRPQKHIQKADIHLVPVLRGQAGEPCEVGQSHKDV
DKEAMMEAGWDPCLQAPFHLTPTLYRTLRNQGNQGAPAESREVLQDTVNLLFNHPRQR
NASRENLNLPEPQPATGQPRSRPLKVAGSPTGRLAGDQGSEEAPQRPPASSATLRRQR
HLNGKVSPEKESGPRQILRSLVRLSVAAFAERNPVEELTVDSPPVQQISQLLSLLHQG
QFQPKPNHRGNKYLAKPGGSRSAIPDTDGPSARAGGQTDPEQEEGPLDPEEDLSVKQL
LEEELSSLLDPSTGLALDRLSAPDPAWMARLSLPLTTNYRDNVISPDAAATEEPRTFQ
TFGKAEAPELSPTGTRLASTFVSEMSSLLEMLLEQRSSMPVEAASEALRRLSVCGRTL
SLDLATSAASGMKVQGDPGGKTGTEGKSRGSSSSSRCL"
BASE COUNT 1276 a 1449 c 1442 g 1038 t
ORIGIN
1 gggaagcggg aggagagcca cacggtcaag ttgcacaggt tcttgcagct tctggaatca
61 agaccatggg caccctcata agtcagtgtg ggcagggact gccccagggc caatccaaga
121 tccagaggta gccatagggt gtgacaagtt gtgcagatta caacactcac cccttgcaat
181 aacgtcactg cctgtgactc ggggccaggc ccaggccaaa gcccttccta catcatttcg
241 tttaatcctc acagtttcct gctgaaaggg ctactattct tactcccatc cccactctac
301 agatgaggta atggaggccc aggaaagtta agtgacttgt cccagatgac accgctggta
361 agttgcaaag tcagaatttg aactcaggca gtttacctct gatggctgct ctgttaatca
421 cagctgcttt ccagtgagac aaaaacgggt gatcagggca gagtcaagac agagaggtaa
481 acaagattgg gaaaaagaca ggaatgagag gggaacaatg ggggaaaaga taggaacaaa
541 gagagttggg gaaggggaga gaaacaggaa acatgacttg cccgggaggg gcatcagtcc
601 acgtgcaagc aggtggaggc tcaagttttc tgctcacttg gtgatgcaga ggctcccttt
661 ccctcagcag ccgccttgct gcgtggacag cagcttccca tctggcctgt ccccggagcc
721 ccggcctcat cctcctcagc ggcaggccac ttagcttcac aggaaatgct ctttctctaa
781 ttggcattga aactcacagc cctccctttt cctgtaggtg gggtttccat aggaaaaagc
841 tgcttctctg tttccccagc ctagcaactg tttggcagtc agagtcccac atcctgctca
901 actgggtcag gtccctctta gaccagctct tgtccatcat ttgctgaagt ggaccaacta
961 gttccccagt agggggtctc ccctggcaat tcttgatcgg cgtttggaca tctcagatcg
1021 cttccaatga agatggcctt gccttggggt cctgcttgtt tcataatcat ctaactatgg
1081 gacaaggttg tgccggcagc tctgggggaa ggagcacggg gctgatcaag ccatccagga
1141 aacactggag gacttgtcca gccttgaaag aactctagtg gtttctgaat ctagcccact
1201 tggcggtaag catgatgcaa cttctgcaac ttctgctggg gcttttgggg ccaggtggct
1261 acttatttct tttaggggat tgtcaggagg tgaccactct cacggtgaaa taccaagtgt
1321 cagaggaagt gccatctggt acagtgatcg ggaagctgtc ccaggaactg ggccgggagg
1381 agaggcggag gcaagctggg gccgccttcc aggtgttgca gctgcctcag gcgctcccca
1441 ttcaggtgga ctctgaggaa ggcttgctca gcacaggcag gcggctggat cgagagcagc
1501 tgtgccgaca gtgggatccc tgcctggttt cctttgatgt gcttgccaca ggggatttgg
1561 ctctgatcca tgtggagatc caagtgctgg acatcaatga ccaccagcca cggtttccca
1621 aaggcgagca ggagctggaa atctctgaga gcgcctctct gcgaacccgg atccccctgg
1681 acagagctct tgacccagac acaggcccta acaccctgca cacctacact ctgtctccca
1741 gtgagcactt tgccttggat gtcattgtgg gccctgatga gaccaaacat gcagaactca
1801 tagtggtgaa ggagctggac agggaaatcc attcattttt tgatctggtg ttaactgcct
1861 atgacaatgg gaaccccccc aagtcaggta ccagcttggt caaggtcaac gtcttggact
1921 ccaatgacaa tagccctgcg tttgctgaga gttcactggc actggaaatc caagaagatg
1981 ctgcacctgg tacgcttctc ataaaactga ccgccacaga ccctgaccaa ggccccaatg
2041 gggaggtgga gttcttcctc agtaagcaca tgcctccaga ggtgctggac accttcagta
2101 ttgatgccaa gacaggccag gtcattctgc gtcgacctct agactatgaa aagaaccctg
2161 cctacgaggt ggatgttcag gcaagggacc tgggtcccaa tcctatccca gcccattgca
2221 aagttctcat caaggttctg gatgtcaatg acaacatccc aagcatccac gtcacatggg
2281 cctcccagcc atcactggtg tcagaagctc ttcccaagga cagttttatt gctcttgtca
2341 tggcagatga cttggattca ggacacaatg gtttggtcca ctgctggctg agccaagagc
2401 tgggccactt caggctgaaa agaactaatg gcaacacata catgttgcta accaatgcca
2461 cactggacag agagcagtgg cccaaatata ccctcactct gttagcccaa gaccaaggac
2521 tccagccctt atcagccaag aaacagctca gcattcagat cagtgacatc aacgacaatg
2581 cacctgtgtt tgagaaaagc aggtatgaag tctccacgcg ggaaaacaac ttaccctctc
2641 ttcacctcat taccatcaag gctcatgatg cagacttggg cattaatgga aaagtctcat
2701 accgcatcca ggactcccca gttgctcact tagtagctat tgactccaac acaggagagg
2761 tcactgctca gaggtcactg aactatgaag agatggccgg ctttgagttc caggtgatcg
2821 cagaggacag cgggcaaccc atgcttgcat ccagtgtctc tgtgtgggtc agcctcttgg
2881 atgccaatga taatgcccca gaggtggtcc agcctgtgct cagcgatgga aaagccagcc
2941 tctccgtgct tgtgaatgcc tccacaggcc acctgctggt gcccatcgag actcccaatg
3001 gcttgggccc agcgggcact gacacacctc cactggccac tcacagctcc cggccattcc
3061 ttttgacaac cattgtggca agagatgcag actcgggggc aaatggagag cccctctaca
3121 gcatccgcag tggaaatgaa gcccacctct tcatcctcaa ccctcatacg gggcagctgt
3181 tcgtcaatgt caccaatgcc agcagcctca ttgggagtga gtgggagctg gagatagtag
3241 tagaggacca gggaagcccc cccttacaga cccgagccct gttgagggtc atgtttgtca
3301 ccagtgtgga ccacctgagg gactcagccc gcaagcctgg ggccttgagc atgtcgatgc
3361 tgacggtgat ctgcctggct gtactgttgg gcatcttcgg gttgatcctg gctttgttca
3421 tgtccatctg ccggacagaa aagaaggaca acagggccta caactgtcgg gaggccgagt
3481 ccacctaccg ccagcagccc aagaggcccc agaaacacat tcagaaggca gacatccacc
3541 tcgtgcctgt gctcaggggt caggcaggtg agccttgtga agtcgggcag tcccacaaag
3601 atgtggacaa ggaggcgatg atggaagcag gctgggaccc ctgcctgcag gcccccttcc
3661 acctcacccc gaccctgtac aggacgctgc gtaatcaagg caaccaggga gcaccggcgg
3721 agagccgaga ggtgctgcaa gacacggtca acctcctttt caaccatccc aggcagagga
3781 atgcctcccg ggagaacctg aaccttcccg agccccagcc tgccacaggc cagccacgtt
3841 ccaggcctct gaaggttgca ggcagcccca cagggaggct ggctggagac cagggcagtg
3901 aggaagcccc acagaggcca ccagcctcct ctgcaaccct gagacggcag cgacatctca
3961 atggcaaagt gtcccctgag aaagaatcag ggccccgtca gatcctgcgg agcctggtcc
4021 ggctgtctgt ggctgccttc gccgagcgga accccgtgga ggagctcact gtggattctc
4081 ctcctgttca gcaaatctcc cagctgctgt ccttgctgca tcagggccaa ttccagccca
4141 aaccaaacca ccgaggaaat aagtacttgg ccaagccagg aggcagcagg agtgcaatcc
4201 cagacacaga tggcccaagt gcaagggctg gaggccagac agacccagaa caggaggaag
4261 ggcctttgga tcctgaagag gacctctctg tgaagcaact gctagaagaa gagctgtcaa
4321 gtctgctgga ccccagcaca ggtctggccc tggaccggct gagcgcccct gacccggcct
4381 ggatggcgag actctctttg cccctcacca ccaactaccg tgacaatgtg atctccccgg
4441 atgctgcagc cacggaggag ccgaggacct tccagacgtt cggcaaggca gaggcaccag
4501 agctgagccc aacaggcacg aggctggcca gcacctttgt ctcggagatg agctcactgc
4561 tggagatgct gctggaacag cgctccagca tgcccgtgga ggccgcctcc gaggcgctgc
4621 ggcggctctc ggtctgcggg aggaccctca gtttagactt ggccaccagt gcagcctcag
4681 gcatgaaagt gcaaggggac ccaggtggaa agacggggac tgagggcaag agcagaggca
4741 gcagcagcag cagcaggtgc ctgtgaacat acctcagacg cctctggatc caagaaccag
4801 gggcctgagg atctgtggac aagagctggt ttctaaaatc ttgtaactca ctagctagcg
4861 gcggcctgag aactttaggg tgactgatgc tacccccaca gaggaggcaa gagccccagg
4921 actaacagct gactgaccaa agcagcccct tgtaagcagc tctgagtctt ttggaggaca
4981 gggacggttt gtggctgaga taagtgtttc ctggcaaaac atatgtggag cacaaagggt
5041 cagtcctctg gcagaacaga tgccacggag tatcacaggc aggaaaggat ggccttcttg
5101 ggtagcagga gtcagggggc tgtaccctgg gggtgccagg aaatgctctc tgacctatca
5161 ataaaggaaa agcagcaaaa aaaaaaaaaa aaaaaaaaaa aaaaa
//