LOCUS AF240634 1299 bp mRNA linear HUM 03-MAY-2000
DEFINITION Homo sapiens phosphoprotein associated with GEMs (PAG) mRNA,
complete cds.
ACCESSION AF240634
VERSION AF240634.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (sites)
AUTHORS Brdicka,T., Pavlistova,D., Leo,A., Bruyns,E., Korinek,V.,
Angelisova,P., Scherer,J., Shevchenko,A., Hilgert,I., Cerny,J.,
Drbal,K., Kuramitsu,Y., Kornacker,B., Horejsi,V. and Schraven,B.
TITLE Phosphoprotein associated with glycosphingolipid-enriched
microdomains (PAG), a novel ubiquitously expressed transmembrane
adaptor protein, binds the protein tyrosine kinase csk and is
involved in regulation of T cell activation
JOURNAL J. Exp. Med. 191 (9), 1591-1604 (2000)
PUBMED 10790433
REFERENCE 2 (bases 1 to 1299)
AUTHORS Brdicka,T., Pavlistova,D., Bruyns,E., Korinek,V., Shevchenko,A.,
Shevchenko,A., Horejsi,V. and Schraven,B.
TITLE Direct Submission
JOURNAL Submitted (01-MAR-2000) Institute for Imunology, Immunomodulation
Laboratory, Ruprecht-Karls University, Im Neuenheimer Feld 305,
Heidelberg 69120, Germany
FEATURES Location/Qualifiers
source 1..1299
/db_xref="H-InvDB:HIT000074813"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="Jurkat"
/cell_type="T-cell"
gene 1..1299
/gene="PAG"
CDS 1..1299
/gene="PAG"
/codon_start=1
/product="phosphoprotein associated with GEMs"
/protein_id="AAF67343.1"
/translation="MGPAGSLLGSGQMQITLWGSLAAVAIFFVITFLIFLCSSCDREK
KPRQHSGDHENLMNVPSDKEMFSRSVTSLATDAPASSEQNGALTNGDILSEDSTLTCM
QHYEEVQTSASDLLDSQDSTGKPKCHQSRELPRIPPESAVDTMLTARSVDGDQGLGME
GPYEVLKDSSSQENMVEDCLYETVKEIKEVAAAAHLEKGHSGKAKSTSASKELPGPQT
EGKAEFAEYASVDRNKKCRQSVNVESILGNSCDPEEEAPPPVPVKLLDENENLQEKEG
GEAEESATDTTSETNKRFSSLSYKSREEDPTLTEEEISAMYSSVNKPGQLVNKSGQSL
TVPESTYTSIQGDPQRSPSSCNDLYATVKDFEKTPNSTLPPAGRPSEEPEPDYEAIQT
LNREEEKATLGTNGHHGLVPKENDYESISDLQQGRDITRL"
BASE COUNT 377 a 325 c 359 g 238 t
ORIGIN
1 atggggcccg cggggagcct gctgggcagc ggacagatgc agatcaccct gtggggaagt
61 ctggctgctg tcgccatttt cttcgtcatc accttcctca tcttcctgtg ctctagttgt
121 gacagggaaa agaagccgcg acagcatagt ggggaccatg agaacctgat gaacgtgcct
181 tcagacaagg agatgttcag ccgttcagtt actagcctgg caacagatgc tcctgccagc
241 agtgagcaga atggggcact caccaatggg gacattcttt cagaggacag tactctgacc
301 tgcatgcagc attacgagga agtccagaca tcggcctcgg atctgctgga ttcccaggac
361 agcacaggga aaccaaaatg tcatcagagt cgggagctgc ccagaatccc tcccgagagc
421 gcagtggata ccatgctcac ggcgagaagt gtggacgggg accaggggct ggggatggaa
481 gggccctatg aagtgctcaa ggacagctcc tcccaagaaa acatggtgga ggactgcttg
541 tatgaaactg tgaaagagat caaggaggtg gctgcagctg cacacctgga gaaaggccac
601 agtggcaagg caaaatctac ttctgcctcg aaagagctcc cagggcccca gactgaaggc
661 aaagctgagt ttgctgaata tgcctcggtg gacagaaaca aaaaatgtcg ccaaagtgtt
721 aatgtagaga gtatccttgg aaattcatgt gatccagaag aggaggcccc accacctgtc
781 cctgttaagc ttctggacga gaatgaaaac cttcaggaga aggaaggggg agaggcggaa
841 gagagtgcca cagacacgac cagtgaaact aacaagagat ttagctcatt gtcatacaag
901 tctcgggaag aagaccccac tctcacagaa gaagagatct cagctatgta ctcatcagta
961 aataaacctg gacagttagt gaataaatcg gggcagtcgc ttacagttcc ggagtccacc
1021 tacacctcca ttcaagggga cccacagagg tcaccctcct cctgtaatga tctctatgct
1081 actgttaaag acttcgaaaa aactccaaac agcacacttc caccagcagg gaggcccagc
1141 gaggagccag agcctgatta tgaagcgata cagactctca acagagagga agaaaaggcc
1201 accctgggga ccaatggcca ccacggtctc gtcccaaagg agaacgacta cgagagcata
1261 agtgacttgc agcaaggcag agatattacc aggctctag
//