LOCUS AF236119 1533 bp mRNA linear HUM 30-JUN-2000
DEFINITION Homo sapiens cell-line H93D8 T cell adapter protein GRID (GRID)
mRNA, complete cds.
ACCESSION AF236119
VERSION AF236119.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1533)
AUTHORS Ellis,J.H., Ashman,C., Burden,M.N., Kilpatrick,K.E., Morse,M.A. and
Hamblin,P.A.
TITLE GRID: a novel Grb-2-related adapter protein that interacts with the
activated T cell costimulatory receptor CD28
JOURNAL J. Immunol. 164 (11), 5805-5814 (2000)
PUBMED 10820259
REFERENCE 2 (bases 1 to 1533)
AUTHORS Ellis,J.H., Ashman,C., Burden,M.N., Kilpatrick,K.E., Morse,M.A. and
Hamblin,P.A.
TITLE Direct Submission
JOURNAL Submitted (18-FEB-2000) Immunopathology Unit, GlaxoWellcome
Medicine Research Centre, Gunnels Wood Road, Stevenage,
Hertfordshire SG1 2NY, UK
FEATURES Location/Qualifiers
source 1..1533
/db_xref="H-InvDB:HIT000074732"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="22"
/map="22q12-22qter"
/cell_line="H93D8 T cell"
gene 1..1533
/gene="GRID"
CDS 224..1216
/gene="GRID"
/note="similar to Homo sapiens adapter protein Gads
encoded by GenBank Accession Number Y18051"
/codon_start=1
/product="adapter protein GRID"
/protein_id="AAF60319.1"
/translation="MEAVAKFDFTASGEDELSFHTGDVLKILSNQEEWFKAELGSQEG
YVPKNFIDIQFPKWFHEGLSRHQAENLLMGKEVGFFIIRASQSSPGDFSISVRHEDDV
QHFKVMRDNKGNYFLWTEKFPSLNKLVDYYRTNSISRQKQIFLRDRTREDQGHRGNSL
DRRSQGGPHLSGAVGEEIRPSMNRKLSDHPPTLPLQQHQHQPQPPQYAPAPQQLQQPP
QQRYLQHHHFHQERRGGSLDINDGHCGTGLGSEMNAALMHRRHTDPVQLQAAGRVRWA
RALYDFEALEDDELGFHSGEVVEVLDSSNPSWWTGRLHNKLGFFPANYVAPMTR"
BASE COUNT 413 a 382 c 411 g 323 t
ORIGIN
1 gtaagangng gggaggagga ggcacagtta atggatctgt aaacttgcac cctctttcag
61 agtggtacat ggaagacagc acaaagtgga tccatactct gaaatgcagt aactctgatg
121 cttgaatttg tctcccttct tgccagaaag gattctaata actcggtgtc aaagccaaga
181 cataaactca accccttctc ttccaaaagc ttcacgttac agcatggaag ctgttgccaa
241 gtttgatttc actgcttcag gtgaggatga actgagcttt cacactggag atgttttgaa
301 gattttaagt aaccaagagg agtggtttaa ggcggagctt gggagccagg aaggatatgt
361 gcccaagaat ttcatagaca tccagtttcc caaatggttt cacgaaggcc tctctcgaca
421 ccaggcagag aacttactca tgggcaagga ggttggcttc ttcatcatcc gggccagcca
481 gagctcccca ggggacttct ccatctctgt caggcatgag gatgacgttc aacacttcaa
541 ggtcatgcga gacaacaagg gtaattactt tctgtggact gagaagtttc cttccctaaa
601 taagctggta gactactaca ggacaaattc catctccaga cagaagcaga tcttccttag
661 agacagaacc cgagaagacc agggtcaccg gggcaacagc ctggaccgga ggtcccaggg
721 aggcccacac ctcagtgggg ctgtgggaga agaaatccga ccttcgatga accggaagct
781 gtcggatcac cccccgaccc ttcccctgca gcagcaccag caccagccac agcctccgca
841 atatgcccca gcgccccagc agctgcagca gcccccacag cagcgatatc tgcagcacca
901 ccatttccac caggaacgcc gaggaggcag ccttgacata aatgatgggc attgtggcac
961 cggcttgggc agtgaaatga atgcggccct catgcatcgg agacacacag acccagtgca
1021 gctccaggcg gcagggcgag tgcggtgggc ccgggcgctg tatgactttg aggccctgga
1081 ggatgacgag ctggggttcc acagcgggga ggtggtggag gtcctggata gctccaaccc
1141 atcctggtgg accggccgcc tgcacaacaa gctgggcttc ttccctgcca actacgtggc
1201 acccatgacc cgataaactc ttcaggggac agaagctttt tgtctggagc tgcccacaag
1261 aaagagggca aggaaaaaag gctggactcc atgactatat atacatacat ctatctacat
1321 ctgcctgtgt acacacacaa ctttttatac tagtaattta ttggcaattg ggctggtaat
1381 tagttgatgc aaaagggaac tcaggtggag nataatattg acacttgctt ttttgccccc
1441 ctcnggggtg tgtggaaggc agtgggggag ttgggagggg ggcagggaaa tgaaatggag
1501 ttttgtcctg gcaaaaaaaa aaaaaaaaaa aaa
//