LOCUS AF231130 6703 bp mRNA linear HUM 02-JAN-2002
DEFINITION Homo sapiens NUP196 nucleoporin mRNA, complete cds.
ACCESSION AF231130
VERSION AF231130.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 6703)
AUTHORS Borrow,J. and Housman,D.E.
TITLE An alternative splice form of NUP98 encodes a 196kDa NUP196 isoform
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 6703)
AUTHORS Borrow,J. and Housman,D.E.
TITLE Direct Submission
JOURNAL Submitted (03-FEB-2000) Center for Cancer Research, Massachusetts
Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA
02139, USA
FEATURES Location/Qualifiers
source 1..6703
/db_xref="H-InvDB:HIT000074607"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="11"
/map="11p15.5"
CDS 145..5547
/note="large alternative splice isoform of NUP98"
/codon_start=1
/product="NUP196 nucleoporin"
/protein_id="AAL56659.1"
/translation="MFNKSFGTPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTSAFGS
SNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLF
SSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGT
TIKFNPPTGTDTMVKAGVSTNISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQ
VGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQ
QNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTA
TNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFG
FGTNTSGNSIFGSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGA
PGFNTTTATLGFGAPQAPVALTDPNASAAQQAVLQQHINSLTYSPFGDSPLFRNPMSD
PKKKEERLKPTNPAAQKALTTPTHYKLTPRPATRVRPKALQTTGTAKSHLFDGLDDDE
PSLANGAFMPKKSIKKLVLKNLNNSNLFSPVNRDSENLASPSEYPENGERFSFLSKPV
DENHQQDGDEDSLVSHFYTNPIAKPIPQTPESAGNKHSNSNSVDDTIVALNMRAALRN
GLEGSSEETSFHDESLQDDREEIENNSYHMHPAGIILTKVGYYTIPSMDDLAKITNEK
GECIVSDFTIGRKGYGSIYFEGDVNLTNLNLDDIVHIRRKEVVVYLDDNQKPPVGEGL
NRKAEVTLDGVWPTDKTSRCLIKSPDRLADINYEGRLEAVSRKQGAQFKEYRPETGSW
VFKVSHFSKYGLQDSDEEEEEHPSKTSTKKLKTAPLPPASQTTPLQMALNGKPAPPPQ
SQSPEVEQLGRVVELDSDMVDITQEPVLDTMLEESMPEDQEPVSASTHIASSLGINPH
VLQIMKASLLTDEEDVDMALDQRFSRLPSKADTSQEICSPRLPISASHSSKTRSLVGG
LLQSKFTSGAFLSPSVSVQECRTPRAASLMNIPSTSSWSVPPPLTSVFTMPSPAPEVP
LKTVGTRRQLGLVPREKSVTYGKGKLLMDMALFMGRSFRVGWGPNWTLANSGEQLNGS
HELENHQIADSMEFGFLPNPVAVKPLTESPFKVHLEKLSLRQRKPDEDMKLYQTPLEL
KLKHSTVHVDELCPLIVPNLGVAVIHDYADWVKEASGDLPEAQIVKHWSLTWTLCEAL
WAHLKELDSQLNEPREYIQILERRRAFSRWLSCTATPQIEEEVSLTQKNSPVEAVFSY
LTGKRISEACSLAQQSGDHRLALLLSQFVGSQSVRELLTMQLVDWHQLQADSFIQDER
LRIFALLAGKPVWQLSEKKQINVCSQLDWKRSLAIHLWYLLPPTASISRALSMYEEAF
QNTSDSDRYACSPLPSYLEGSGCVIAEEQNSQTPLRDVCFHLLKLYSDRHYDLNQLLE
PRSITADPLDYRLSWHLWEVLRALNYTHLSAQCEGVLQASYAGQLESEGLWEWAIFVL
LHIDNSGIREKAVRELLTRHCQLLETPETWAKETFLTQKLRVPAKWIHEAKAVRAHME
SDKHLEALCLFKAEHWNRCHKLIIRHLASDAIINENYDYLKGFLEDLAPPERSSLIQD
WETSGLVYLDYIRVIEMLRHIQQVDCSGNDLEQLHIKVTSLCSRIEQIQCYSAKDRLA
QSDMAKRVANLLRVVLSLHHPPDRTSDSTPDPQRVPLRLLAPHIGRLPMPEDYAMDEL
RSLTQSYLRELAVGSL"
BASE COUNT 1809 a 1635 c 1554 g 1705 t
ORIGIN
1 cggtggcagg ggtggtagcg gcggcggcga cggtttcgtg ggggccgcgc gctgctctgt
61 gagcggcggg tggcagcagg ggactcctga cacttcccct tccccaccga accgcgcttt
121 ctgaaacaaa gactcatttt gaagatgttt aacaaatcat ttggaacacc ctttgggggt
181 ggcacaggtg gctttggcac aacttcaaca tttggacaga atactggctt tggcactact
241 agtggagggg catttggaac atctgcattt ggttctagca acaatactgg aggcctcttt
301 ggaaattcac agactaaacc aggaggattg tttggaacca gttcatttag ccagccagct
361 acctccacaa gcactggctt tgggtttggt acgtcaacag gaacagcaaa taccttgttt
421 ggaactgcaa gcacagggac cagtctcttc tcatcccaaa acaatgcctt tgcacaaaat
481 aaaccaactg gctttggcaa ttttggaacc agtactagca gtggaggact ctttggaacc
541 acaaatacca cctctaatcc ttttggcagc acatctggct ccctctttgg gccaagtagt
601 tttacagctg ctcctactgg gactactatt aaatttaacc ctccaactgg tacagatact
661 atggtcaaag ctggagttag cactaacata agtaccaagc accagtgtat tactgctatg
721 aaagaatatg aaagcaagtc actagaggaa cttcgtttag aggattatca ggctaacagg
781 aagggcccac agaaccaggt gggagcaggt accacaactg gcttgtttgg gtcttctcca
841 gccacttcca gcgcaacagg actcttcagc tcctccacca ctaattcagg ctttgcatat
901 ggtcagaaca aaactgcctt tggaactagt acaactggat ttggaacaaa tccaggtggt
961 ctctttggcc aacagaatca gcagactacc agcctcttca gcaaaccatt tggccaggct
1021 acaaccaccc agaacactgg cttttccttt ggtaatacca gcaccatagg acagccaagc
1081 accaacacca tgggattatt tggagtaacc caagcctcac agcctggagg tctttttggg
1141 acagctacaa acaccagcac tgggacagca tttggaacag gaacaggtct ctttgggcag
1201 accaatactg gatttggtgc tgttggttcg accctgtttg gcaataacaa gcttactaca
1261 tttggaagca gcacaaccag tgcaccttca tttggtacaa ccagtggcgg gctctttggt
1321 tttggcacaa ataccagtgg gaatagtatt tttggaagta aaccagcacc tgggactctt
1381 ggaactgggc ttggtgcagg atttggaaca gctcttggtg ctggacaggc atctttgttt
1441 gggaacaacc aacctaagat tggagggcct cttggtacag gagcctttgg ggcccctgga
1501 tttaatacta cgacagccac tttgggcttt ggagcccccc aggccccagt agctttgaca
1561 gatccaaatg cttctgctgc ccagcaggct gttctccagc agcacatcaa tagtctaaca
1621 tactcacctt ttggagactc tcctctcttc cggaatccga tgtcagaccc taagaagaag
1681 gaagagagat tgaaaccaac aaatccagca gcccagaagg ctcttactac acctactcat
1741 tataaactga caccccgccc tgccactaga gtccggccaa aggctttaca aacaacaggc
1801 acagccaagt cacatctctt tgatgggctg gatgacgatg aaccatccct agccaatgga
1861 gcattcatgc ccaagaagag cattaagaag ttggttttga agaaccttaa taatagcaat
1921 ctcttttctc ctgttaatcg tgattcagaa aatctagctt caccatctga atatccagaa
1981 aatggagaga gatttagttt cctaagcaaa cctgttgatg agaatcacca gcaggatgga
2041 gatgaagatt cccttgtttc acatttttat actaacccta ttgccaaacc tattcctcaa
2101 accccagaaa gtgctggaaa taaacacagc aacagcaaca gtgtggatga taccattgtt
2161 gcattaaaca tgcgtgctgc tttgcgaaat gggctggaag gaagcagtga agaaacgtct
2221 tttcatgatg agtcacttca ggatgaccga gaagaaatag aaaataattc ttaccatatg
2281 cacccagcag gtattattct cactaaggtt ggttactata ctattccatc tatggatgac
2341 cttgctaaaa ttaccaatga aaaaggagag tgcattgtct ctgatttcac tattggtcgg
2401 aaaggttatg gttcaatcta ttttgaagga gatgtgaatt tgacaaatct aaatttggat
2461 gatattgtgc atatccggag gaaagaagta gttgtctact tagatgataa ccaaaaacca
2521 cctgtgggtg aagggctaaa taggaaggct gaagttacat tggatggagt ttggccaaca
2581 gataaaacat ctcgttgttt aataaagagc ccagatcgcc ttgctgatat caactatgaa
2641 ggaagattgg aagcagtttc aaggaaacag ggagctcaat tcaaagaata ccggcctgaa
2701 actggttctt gggtgtttaa ggtctcccat ttttctaagt atggccttca ggattctgat
2761 gaagaggagg aggagcatcc gtctaaaact agtacaaaga agttgaagac tgctcctttg
2821 cctcctgcaa gccagactac gcccttgcag atggctctta atggcaaacc tgcacctcca
2881 cctcagagcc agagcccaga ggtggagcag ttagggaggg ttgtggaact ggacagtgac
2941 atggtagata tcacccagga gccagtgttg gataccatgt tagaagagag catgcctgag
3001 gatcaggaac ctgtgtctgc ctcaacacat attgcatctt cactgggaat taatccacat
3061 gtcttacaga tcatgaaagc atcattgctt actgatgaag aagatgtaga tatggcactg
3121 gatcaacgct tcagtcgcct gccttccaaa gcagatactt ctcaagaaat ctgttctccc
3181 agactcccca tttcagcatc ccactcgtcg aaaactcgtt cactagttgg tgggttacta
3241 caatcaaaat ttacaagtgg agcttttctt tcaccaagtg tctctgtgca agaatgtcgt
3301 actcccagag cagcatcttt aatgaatatc ccatccacat cctcttggtc tgtccctcca
3361 cccctgactt ctgtgttcac aatgcccagc ccagcccctg aggttccgtt gaaaacagtg
3421 ggtacacgta ggcaactagg cctagtgcct cgtgaaaagt ctgtcaccta tggcaaggga
3481 aaactcttga tggacatggc cctattcatg ggacgctcat ttcgtgttgg ttggggcccc
3541 aactggactc ttgctaatag tggagaacag ctgaatggct ctcatgaact agaaaatcat
3601 cagattgccg attccatgga gtttggattc ctgcccaatc cagtagctgt taaaccccta
3661 actgagtccc cattcaaagt tcacttagaa aaactcagtt tgagacaaag aaagccagat
3721 gaagacatga aattatatca gacacctctg gagctcaaat taaaacacag cactgtccat
3781 gtggatgaac tgtgtcctct cattgtcccc aatctgggag ttgctgtcat tcatgactat
3841 gcagattggg ttaaagaagc atcaggagac ttaccagaag cacaaattgt gaagcactgg
3901 agcctgacat ggacactatg tgaagcccta tgggcccacc tgaaggagct tgacagccag
3961 ctaaatgaac cccgtgaata cattcaaatt ctggagcgaa gaagagcttt ctcccgctgg
4021 ctatcctgta ctgccacacc tcagattgaa gaggaagtct ccttaaccca aaaaaacagc
4081 cctgtggagg ctgtattcag ctacctcaca ggcaaaagga tcagtgaggc ctgctctctg
4141 gcccagcagt caggggatca tcgtcttgct cttcttttat ctcagtttgt gggtagccag
4201 tcagtccggg agctgctcac catgcagttg gtggactggc atcagctcca agcagactcc
4261 ttcatccagg atgagagact gcgcatcttt gctctgttgg ctggaaaacc ggtgtggcag
4321 ctctcagaaa agaagcaaat aaacgtgtgc tcccagttgg attggaaacg ctccctggct
4381 atccatcttt ggtatttgct tccaccaaca gcctccattt ctagggcgct cagcatgtat
4441 gaagaagcat ttcagaatac ctctgacagt gacagatatg cctgctcccc acttccttcg
4501 tatctggagg gttctggctg tgtgatagcg gaggagcaaa actcacagac accacttcga
4561 gatgtctgct ttcaccttct aaaactctac agtgacagac attatgatct caaccagctg
4621 ctggagcctc gaagcataac agcagatcct ttggactacc gcctaagctg gcacttgtgg
4681 gaagtgctga gggctcttaa ctacacccat ctctcagcgc agtgtgaagg tgtgctacag
4741 gccagttacg ctggccagct tgaaagtgag gggctctggg agtgggccat ctttgtcctc
4801 ctgcacattg acaactcagg catacgtgag aaggctgttc gagagctgct tacccggcac
4861 tgccagctgt tggagacccc tgagacttgg gctaaagaga ctttccttac ccagaagctc
4921 cgtgtacctg ccaaatggat ccacgaggcc aaagctgtgc gagcacacat ggaatctgac
4981 aagcacttag aggccctttg cttatttaag gctgagcact ggaaccgctg ccacaagctc
5041 atcatccgac acttagcttc tgatgccatc attaatgaga actatgacta cctgaagggg
5101 ttcttggaag acctggcacc tccagagcgc agcagcctaa ttcaggattg ggaaacatct
5161 gggcttgttt acctggacta tattagagtc attgaaatgc tccgccatat acagcaggtg
5221 gattgctcag gtaatgacct ggagcagtta cacatcaaag tgacttcact gtgcagtcgg
5281 atagagcaga ttcagtgtta cagtgctaaa gatcgcctgg ctcagtcaga catggccaaa
5341 cgtgtagcca acctgctgcg cgtggtgctg agtctgcatc atcctcctga tagaacctcc
5401 gactcaacac cagaccctca gcgagtccct ttgcgcctct tggctcccca cattggccgg
5461 cttcccatgc ctgaggacta tgccatggac gaactgcgca gccttaccca gtcctatctg
5521 cgagaactgg ctgttgggag cctgtgagcc ccaggcactt tgcatcacag tcacatgccc
5581 attcacacca cacagaggtt ccctgccttg tttggattgg cactgtttgc cattctctgg
5641 gttggctgtg gcatctaccc tccctccctg ctgccagaag cagcatcctc cacttgttca
5701 gggcttttct taatactgaa cgtagcataa gggcttctgg aacccagaag aggagacagt
5761 ttaccatcct caagatcatt cagtgttttt cctttaaaaa aatggtcaat aaagctcctt
5821 tggcagaatc ccccaaagaa ccagggtatt ctttttccat ccctagccat tctggatctt
5881 gtgaccctcc atgccaacca gcttccctac tcctaccctg gcccttttat actaggactc
5941 cttaggagga gtgagacagg tgataatgga tccttaacag atgaactatc cacagaagga
6001 agagggatcc gtctcttaag taattggtta gttaacactg aattttggag gcaaaggagg
6061 gttggcctga gttaggaaac aaaatgggat ctttctgaca cacttagggc agaagtgaat
6121 gcctgtcacg gagggattga tcttcagggc tgtttttgtt cctgccttta gagttccatg
6181 aacaccatac ctttgctact actatgtgca ggaacccttg gtcacatgtg acatgtctgt
6241 gggaagctcc cagagtttgg tttggtccct ggttttcagt cttgctgaga ctctgtctgg
6301 atttgcctgc agagtttgga taaaaaatgg caggttgggt aaccctccct gttcatccca
6361 tgttagctcc aaagcatttc ccaccctcca tctacccctt ccagaagcaa aaacaaacca
6421 tgactgaggc aggcatggag ttgggcgtta ggggcaggca gagggccttt gctacactgc
6481 tgacagctat agggagcccc aggtaatggc atgagatagc tggtgttagg gctatctcag
6541 gcaatatggc cacacctggg tctttatgca tgaagataat gtaaaggttt ttattaaaaa
6601 atatatatat gtataaataa atgatctaga tattttcctc tttttctgaa gctactttct
6661 taaaaaataa ataaaatgtt tatagcattc ctggtaaaaa aaa
//