LOCUS AF229178 3199 bp mRNA linear HUM 05-JUN-2000
DEFINITION Homo sapiens leucine rich repeat and death domain containing
protein (LRDD) mRNA, complete cds.
ACCESSION AF229178
VERSION AF229178.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3199)
AUTHORS Telliez,J.B., Bean,K.M. and Lin,L.L.
TITLE LRDD, a novel leucine rich repeat and death domain containing
protein
JOURNAL Biochim. Biophys. Acta 1478 (2), 280-288 (2000)
PUBMED 10825539
REFERENCE 2 (bases 1 to 3199)
AUTHORS Telliez,J.-B., Bean,K. and Lin,L.-L.
TITLE Direct Submission
JOURNAL Submitted (28-JAN-2000) Small Molecule Drug Discovery group,
Genetics Institute Inc., 87 Cambridge Park drive, Cambridge, MA
02140, USA
FEATURES Location/Qualifiers
source 1..3199
/db_xref="H-InvDB:HIT000074521"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene 1..3199
/gene="LRDD"
CDS 788..3049
/gene="LRDD"
/note="protein has a death domain at the carboxyl-terminus
and leucine rich repeats at the amino-terminus and a ZU5
domain in the intermediate region"
/codon_start=1
/product="leucine rich repeat and death domain containing
protein"
/protein_id="AAF69491.1"
/translation="MRGLGALLLSHNCLSELPEALGALPALTFLTVTHNRLQTLPPAL
GALSTLQRLDLSQNLLDTLPPEIGGLGSLLELNLASNRLQSLPASLAGLRSLRLLVLH
SNLLASVPADLARLPLLTRLDLRDNQLRDLPPELLDAPFVRLQGNPLGEASPDAPSSP
VAALIPEMPRLFLTSDLDSFPVTPRGCSVTLACGVRLQFPAGATATPITIRYRLLLPE
PGLVPLGPHDALLSHVLELQPHGVAFQQDVGLWLLFTPPQARRCREVVVRTRNDNSWG
DLETYLEEEAPQRLWAHCQVPHFSWFLVVSRPVSNACLVPPEGTLLCSSGHPGVKVIF
PPGATEEPRRVSMQVVRMAGRELQALLGEPEAAVSPLLCLSQSGPPSFLQPVTVQLPL
PSGITGLSLDRSRLHLLYWAPPAATWDDITAQVVLELTHLYWLWYTTKNCVGGLARKA
WERLRLHRVNLIALQRRRDPEQVLLQCLPRNKVDATLRRLLERYRGPEPSDTVEMFEG
EEFFAAFERGIDVDADRPDCVEGRICFVFYSHLKNVKEVYVTTTLDREAQAVRGQVSF
YRGAVPVRVPEEAEAARQRKGADALWMATLPIKLPRLRGSEGPRRGAGLSLAPLNLGD
AETGFLTQSNLLSVAGRLGLDWPAVALHLGVSYREVQRIRHEFRDDLDEQIRHMLFSW
AERQAGQPGAVGLLVQALEQSDRQDVAEEVRAVLELGRRKYQDSIRRMGLAPKDPVLP
GSSAPQPPEPAQA"
BASE COUNT 501 a 1112 c 977 g 609 t
ORIGIN
1 tctcctgcgt agccatggcg gtcccattcc ccaaccctct ttccagtggt gacccaagcc
61 tccggggttc agggtgacca caatgtctcc cccactctgc atcccaggcc catatggcct
121 ggctctagag ctccccactc catccagagt ccctgtttcc ccaaagagaa gggcccaccc
181 cggctcccgc tcactcctcc tcctgcctct gcatcttccc cgggcgctgc ctggacaggc
241 ctgcctgcgt gctgggacat gtctggcctc caaggaccgt cggtgggcga tggctgcaac
301 ggtggagggg ccagagctgg aggcagctgc tgccgcagga gatgcttcag aggattcgga
361 cgcagggtcc agggcgcttc ctttcctggg cggcaaccgg ctgagcttgg acctgtaccc
421 cgggggctgc cagcagctgc tgcacctgtg tgtccagcag cctcttcagc tgctgcaggt
481 ggaattcttg cgtctgagca ctcacgagga ccctcagctg ctggaggcca ccctggccca
541 gctgcctcag agcctgtcct gcctccgctc cgtggtcctc aaagggtcga tctgggacct
601 cggaccctgg ctctgagggc cacatccgcc tccccccttc ccaggagggc aacgccggga
661 cacactgggt gcctgtctcc ggggtgccct gaccaacctg cccgctggtc tgagtggcct
721 ggcccatctg gcccacctgg acctgagctt caacagcctg gagacactgc cggcctgtgt
781 cctgcagatg cgaggtctgg gtgcgctctt gctgtctcac aactgcctct ctgagctgcc
841 tgaggctctg ggggccctcc ccgccctcac cttcctcaca gtgacacaca accgcctgca
901 gacgctgccc ccagcactgg gggccctatc caccctgcag cgcctcgatc tctctcagaa
961 tctgctggac acgctacctc ctgagattgg aggcctgggc agcctcctgg agctcaacct
1021 ggcctccaac cggctgcaga gcctcccagc ctctctggcg ggacttcggt ccttgcggct
1081 ccttgtcctg cacagcaacc tcctggcctc tgtgccagct gacttggccc gccttccact
1141 cctcacccgg ctcgacctga gggacaacca gctccgggac ctgccccctg agctgctaga
1201 cgcccccttt gtgcgcctgc aggggaaccc cctgggtgag gcctcgccag acgccccgag
1261 ttcaccagtg gcagccctca ttccagaaat gcccagactg ttcctgacct cagatttgga
1321 cagctttcct gtgacccctc gaggctgctc agtgaccctg gcctgtggcg tccgcctgca
1381 gttcccagcg ggagccaccg ccacccccat caccatccgc tatcggctgc tgctgccgga
1441 gccaggcctc gtccccctgg gtcctcatga cgccctgctc agccatgtgc tggagctgca
1501 gccccatggg gtggccttcc agcaggatgt ggggctgtgg ctgctcttca ccccaccgca
1561 ggcccggcgc tgccgtgaag tggtggtcag gacccggaat gacaacagct ggggtgacct
1621 ggagacctac ctggaggaag aggcacccca gcggctctgg gctcactgcc aggtgcccca
1681 cttctcctgg ttccttgtgg tttcccgccc tgtgtccaat gcctgcctgg tgccaccgga
1741 ggggacactg ctgtgctcct cgggtcatcc tggggtcaaa gtcatcttcc cccctggggc
1801 cactgaggag cctcgtcgag tctccatgca ggtggtgcgc atggctggcc gagagctgca
1861 ggccctcctg ggagaaccag aggctgcagt gagccccctg ctgtgcctgt cacagagcgg
1921 tccccccagc ttcctccaac cggtcaccgt gcagctgcct ctgccctctg gcatcacagg
1981 cctcagtctg gaccgctccc gcctgcacct gttgtactgg gcccctcctg cagccacctg
2041 ggatgacatc acagctcagg tggtcctgga gctcacccac ctgtactggc tctggtacac
2101 caccaagaac tgtgtgggag gcctggctcg gaaggcctgg gagcggctgc ggctgcaccg
2161 tgtgaacctc atcgctctgc agcggcgccg ggaccctgag caggtcctgc tgcagtgcct
2221 gccccgaaac aaggtggacg ccacccttcg gcggctgctg gagcggtacc ggggccccga
2281 gccctctgac acggtggaga tgttcgaggg cgaagagttc tttgcggcct tcgagcgcgg
2341 catcgacgtg gatgctgacc gccctgactg tgtggagggc agaatctgct ttgtcttcta
2401 ctcgcacctg aagaatgtga aggaggtata cgtgaccacc actctggacc gggaggctca
2461 ggctgtgcgg ggccaggtgt ccttctaccg tggcgcggtg cctgtgcggg tgcccgagga
2521 ggctgaggct gcccggcaga ggaagggcgc agacgccctg tggatggcca ctctgcccat
2581 caagctgccg agacttcgag ggtccgaggg gccacggcgg ggggctggcc tctccttggc
2641 acccttgaat ctgggagatg ccgagaccgg ctttctgacg cagagcaacc tgctgagtgt
2701 ggctgggcgt ctgggtctgg actggccagc cgtggccctg cacctggggg tgtcctaccg
2761 ggaggtgcag cgcatccggc acgagttccg ggatgatctg gatgagcaga tccgtcacat
2821 gctcttctcc tgggctgagc gccaggctgg gcagccaggg gctgtggggc tcctggtgca
2881 ggccctggag cagagtgacc ggcaggacgt ggctgaagag gtgcgcgcag tcttggagct
2941 cggccgccgc aagtaccagg acagcatccg acgcatgggc ttggccccca aggaccccgt
3001 tctgcctggc tcctcggctc cacagccccc agagcctgcc caggcatagg ccccacagaa
3061 ttttaggctg gcccagatat tccccagtgg atgggcagag cccccacctt caagtctctc
3121 cagtgtgtgg ggacgggtcc ctgtgagcaa caaaactgca ctgtttcttt cacctcgaaa
3181 aaaaaaaaaa aaaaaaaaa
//