LOCUS AF229172 5035 bp mRNA linear HUM 22-AUG-2000
DEFINITION Homo sapiens class III myosin (MYO3A) mRNA, complete cds,
alternatively spliced.
ACCESSION AF229172
VERSION AF229172.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5035)
AUTHORS Dose,A.C. and Burnside,B.
TITLE Cloning and chromosomal localization of a human class III myosin
JOURNAL Genomics 67 (3), 333-342 (2000)
PUBMED 10936054
REFERENCE 2 (bases 1 to 5035)
AUTHORS Dose,A.C. and Burnside,B.
TITLE Direct Submission
JOURNAL Submitted (28-JAN-2000) Molecular and Cell Biology, University of
California, Berkeley, LSA 335/3200, Berkeley, CA 94720, USA
FEATURES Location/Qualifiers
source 1..5035
/db_xref="H-InvDB:HIT000074519"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="10"
/map="near D10S197"
/cell_line="ARPE-19; from retina"
gene 1..5035
/gene="MYO3A"
CDS 179..5026
/gene="MYO3A"
/note="expressed in retina, retinal pigment epithelial
cells and pancreas; alternatively spliced"
/codon_start=1
/product="class III myosin"
/protein_id="AAF70861.1"
/translation="MFPLIGKTIIFDNFPDPSDTWEITETIGKGTYGKVFKVLNKKNG
QKAAVKILDPIHDIDEEIEAEYNILKALSDHPNVVRFYGIYFKKDKVNGDKLWLVLEL
CSGGSVTDLVKGFLKRGERMSEPLIAYILHEALMGLQHLHNNKTIHRDVKGNNILLTT
EGGVKLVDFGVSAQLTSTRHRRNTSVGTPFWMAPEVIACEQQLDTTYDARCDTWSLGI
TAIELGDGDPPLADLHPMRALFKIPRNPPPKLRQPELWSAEFNDFISKCLTKDYEKRP
TVSELLQHKFITQIEGKDVMLQKQLTEFIGIHQCMGGTEKARRERIHTKKGNFNRPLI
SNLKDVDDLATLEILDENTVSEQLEKCYSRDQIYVYVGDILIALNPFQSLGLYSTKHS
KLYIGSKRTASPPHIFAMADLGYQSIITYNSDQCIVISGESGAGKTENAHLLVQQLTV
LGKANNRTLQEKILQVNNLVEAFGNACTIINDNSSRFGKYLEMKFTSSGAVVGAQISE
YLLEKSRVIHQAIGEKNFHIFYYIYAGLAEKKKLAHYKLPENKPPRYLQNDHLRTVQD
IMNNSFYKSQYELIEQCFKVIGFTMEQLGSIYSILAAILNVGNIEFSSVATEHQIDKS
HISNHTALENCVSLLCIRADELQEALTSHCVVTRGETIIRPNTVEKATDVRDAMAKTL
YGRLFSWIVNCINSLLKHDSSPSGNGDELSIGILDIFGFENFKKNSFEQLCINIANEQ
IQYYYNQHVFAWEQNEYLNEDVDARVIEYEDNWPLLDMFLQKPMGLLSLLDEESRFPK
ATDQTLVEKFEGNLKSQYFWRPKRMELSFGIHHYAGKVLYNASGFLAKNKTLVPTDIV
LLLRSSDNSVIRQLVNHPLTKTGNLPHSKLKMLNYQMRTSEKLINLAKGDTGEATRHA
RETTNMKTQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNSERQARKYDKEKVLLQLR
YTGILETARIRRLGFSHRILFANFIKRYYLLCYKSSEEPRMSPDTCATILEKAGLDNW
ALGKTKVFLKYYHVEQLNLMRKEAIDKLILIQACVRAFLCSRRYQKIQEKRKESAIII
QSAARGHLVGKQRKEIVDMKNTAVTTIQTSDQEFDYKKNFENTRESFVKKQAENAISA
NERFISAPNNKGSVSVVKTSTFKPEEETTNAVESNNRVYQTPKKMNNVYEEEVKQEFY
LVGPEVSPKQKFVKDLEENSNLRKVEKEEAMIQSYYQRYTEERNCEESKAAYLERKAI
SERPSYPVPWLAENETSFKKTLEPTLSQRSIYQNANSMEKEKKTSVVTQSAPICSQEE
GRGRLRHETVKERQVEPVTQAQEEEDKAAVFIQSKYRGYKRRQQLRKDKMSSFKHQKI
VTTPTEVARNTHNLYSYPTKHEEINNIKKKDNKDSKATSEREACGLAIFSKQISKLSE
EYFILQKKLNEMILSQQLKSLYLGVSHHKPINRRVSSQQCLSGVCKGEEPKILRPPRR
PRKPKTLNNPEDSTYYYLLHKSIQEEKRRPRKDSQGKLLDLEDFYYKEFLPSRSGPKE
HSPSLRERRPQQELQNQCIKANERCWAAESPEKEEEREPAANPYDFRRLLRKTSQRRR
LVQQS"
BASE COUNT 1737 a 994 c 1071 g 1233 t
ORIGIN
1 cttaattcta gaagggagcg cccgtagcca gcgcccccgt aaagaaataa ggaggcgccc
61 ggcttcccgc ccaggcccag ggccccagtg cagcctggac acagtattca aagttttggc
121 gtctgagcat tgttatgcgt tattttcaag ctttgctaac ggtttttaaa cctttgagat
181 gtttccatta attggaaaaa caatcatctt tgataacttt cctgatcctt ctgatacatg
241 ggaaatcact gagacaattg gcaaaggaac ttatgggaaa gtttttaaag tattgaataa
301 gaaaaatggc caaaaagcag cagtcaaaat tcttgatcca attcacgata ttgacgaaga
361 gattgaagca gaatataaca tcttaaaagc actttctgac caccctaatg tggtcagatt
421 ctatgggata tactttaaga aggataaagt aaatggagac aagctgtggt tggttcttga
481 gctctgcagt ggaggatcag tgactgacct tgtgaaagga tttctgaaga ggggtgaaag
541 aatgagtgag cctctaattg cctatatttt acatgaagca ctaatgggac ttcaacattt
601 gcataacaac aaaactatcc acagagatgt gaaaggcaat aacattctat tgaccacgga
661 aggtggagtg aaactagtag attttggtgt gtctgcacag ctcaccagta cccggcaccg
721 tcggaacaca tccgtaggaa caccgttttg gatggctcct gaggtgattg catgtgaaca
781 gcaattggat accacttatg acgccagatg tgacacttgg tccctgggta tcacggccat
841 tgagctgggt gatggagatc ctccactagc tgaccttcat cccatgagag cactcttcaa
901 aataccaagg aatccacccc caaaactaag gcagcctgag ctatggtcag cagaattcaa
961 tgacttcata agcaagtgct tgactaaaga ttatgaaaag cgtccaacag tgtcagaact
1021 tttacagcat aaattcatta ctcaaattga gggcaaagat gtgatgctac aaaaacaact
1081 aacggaattc attggcatcc atcaatgcat gggaggcaca gaaaaggcca gacgtgaacg
1141 tattcacacg aagaaaggga acttcaaccg acctctaata tccaatctga aggatgtaga
1201 tgatttagca accctagaaa ttttggatga gaatacagtc tcagagcaac ttgagaagtg
1261 ttattccaga gatcagatct acgtctatgt gggagacata ctcattgctc ttaacccttt
1321 tcagagtctg ggtctttact ccacaaagca ttccaaacta tatattggat caaagagaac
1381 tgccagtcct cctcacattt ttgcaatggc tgacttagga tatcaatcta taataacata
1441 taattcagat cagtgcattg ttatttctgg agaaagtggt gctggaaaga ctgaaaatgc
1501 tcatctttta gttcagcagc tgacagtgct tggaaaggct aataacagaa ccttgcaaga
1561 gaagatttta caagtgaaca atttggtaga agcctttggc aatgcctgca ctattataaa
1621 tgacaattct agcagatttg gaaaatactt agaaatgaaa ttcacctctt ctggagcggt
1681 agtgggagca cagatttctg aatatctcct ggaaaaatcc cgagttatcc accaagctat
1741 tggagaaaaa aattttcata ttttttacta catttatgct ggtttggctg aaaagaagaa
1801 actagcccat tacaaactgc ctgaaaataa gcctcccagg tacctacaaa atgaccacct
1861 cagaacagta caagacatca tgaataatag tttctataaa tcccagtatg aattaattga
1921 gcaatgtttc aaagtcatag gttttacaat ggagcaactt ggtagtatat acagcatact
1981 cgctgcaatc ttgaatgttg gcaacattga attttcttct gtggcaactg aacaccagat
2041 tgacaagagc cacatttcta atcatacagc cctggagaac tgtgtttctt tgctttgcat
2101 tcgggcagat gagctacaag aagctctcac ctcccactgt gtggtcacta gaggagaaac
2161 aattatacga cccaatactg tagaaaaagc taccgatgtc agggatgcca tggctaaaac
2221 tttatatgga cgtctcttta gttggatagt caattgcatt aacagtttgt tgaagcatga
2281 ctcatcacca agtgggaatg gtgatgagct gagcattggc attcttgata tatttggttt
2341 tgaaaatttc aaaaaaaatt ccttcgagca gctgtgcatt aacattgcaa atgaacaaat
2401 tcagtattat tataatcaac atgtgtttgc atgggaacag aatgaatacc taaatgaaga
2461 tgtggatgct agagttattg aatatgagga taactggccc ctcttagata tgtttctgca
2521 aaagccaatg ggtttacttt ccctacttga tgaagaaagt agatttccca aggccactga
2581 ccagactctt gtagaaaaat ttgaaggtaa cctgaaatca caatacttct ggagacccaa
2641 aagaatggaa cttagttttg gaattcacca ttatgcagga aaggtcctct ataatgcaag
2701 tggattctta gccaaaaaca agacactagt tcctactgac attgtgctac ttttgaggtc
2761 atccgacaac agtgtaatta ggcaactagt caaccaccct ctgaccaaaa caggtaatct
2821 gccacattct aaactaaaaa tgttaaacta tcaaatgagg acttcagaaa aattaatcaa
2881 cctggcaaag ggcgacactg gagaagccac acgtcatgcc agagagacaa ccaacatgaa
2941 aacacaaacg gttgcatcat attttagata ttccctgatg gatttgttgt ctaaaatggt
3001 ggtgggccaa cctcattttg tccgttgcat caaaccaaat agtgagcgtc aggcaagaaa
3061 atatgacaaa gagaaagttc tgctacagct tcggtacaca ggaattctgg aaacagcaag
3121 aattcgaaga ctaggattct cccatcggat actttttgct aactttataa agcggtacta
3181 ccttctctgc tacaagtcga gcgaggagcc ccgcatgagc cctgacacct gtgccaccat
3241 tttggaaaaa gctggtctcg ataactgggc tcttggaaaa acaaaagtgt tccttaagta
3301 ttatcacgtg gagcagttaa atctaatgcg aaaggaagct attgacaagc ttattttgat
3361 tcaagcttgt gtcagagcat tcttgtgttc aagaagatac caaaaaatac aggagaaaag
3421 gaaagaaagc gctataataa tacagtcagc tgcaagagga caccttgtcg ggaaacaaag
3481 aaaagaaatt gttgacatga aaaacacagc agtaacaacc attcaaactt ctgatcagga
3541 attcgactac aagaaaaact ttgaaaatac aagggaatct ttcgtgaaga aacaagcaga
3601 aaatgcaatc tctgctaatg aaagattcat ttcagctcca aataataaag gaagtgtatc
3661 tgtagtgaag acttccactt tcaaacctga agaggaaacc accaatgctg tggagagtaa
3721 caacagagtg tatcagactc caaaaaaaat gaataatgtg tatgaggaag aggttaagca
3781 agaattttac cttgtagggc cagaagtaag ccccaaacag aagtttgtca aagacctgga
3841 agagaacagc aatctaagga aagtggagaa agaggaagct atgatccaga gttactatca
3901 gaggtacaca gaggagagga attgtgaaga gtcaaaagca gcatatctag aaaggaaggc
3961 catatcagaa aggccaagct acccagtgcc ttggttagct gaaaatgaga cttcctttaa
4021 aaaaactttg gaacctacac ttagccaaag gtcaatttat caaaatgcaa acagcatgga
4081 aaaagaaaag aagacatctg tagttaccca gagtgcaccg atatgcagcc aggaggaagg
4141 cagaggccgt ctgaggcatg agacagtcaa agagaggcaa gttgaaccag tgacacaggc
4201 ccaggaggaa gaagataaag cagcggtatt cattcagagc aaataccggg gttacaagag
4261 aaggcagcag ttgaggaagg acaagatgtc ttcttttaag catcagaaga ttgtcacaac
4321 accaacagaa gtagcaagaa acactcataa tttgtattcc tatcccacaa aacatgagga
4381 aatcaataac atcaagaaga aggataacaa agactcgaaa gcaacttcag aaagagaagc
4441 atgtggtttg gcaatttttt caaaacagat atcaaagtta tctgaagaat atttcattct
4501 gcagaaaaaa ttgaatgaaa tgattttgtc acagcaactg aagtcacttt atctgggtgt
4561 ctcgcaccat aagccaatta atagacgagt ttcttctcag cagtgcctct caggtgtctg
4621 taaaggagag gagccaaaaa tattgagacc cccaagacga ccccggaaac ccaaaacatt
4681 aaataaccct gaagactcca catactatta tctacttcat aagtcaatcc aagaagaaaa
4741 acgaagacca aggaaagaca gtcagggaaa attattagat ttggaagatt tctattataa
4801 ggaatttttg cccagtcgtt ctggaccaaa ggaacatagc cctagtttaa gagaacgaag
4861 accacagcaa gaactccaga atcaatgtat taaggctaat gaaaggtgct gggcggcgga
4921 gagccccgag aaggaggagg agagagagcc agcagccaac ccctacgact tcaggaggct
4981 cctgcgcaaa acctcccagc gccggcgcct cgtccagcag tcctaaccgt tcaac
//