LOCUS AF228520 2135 bp mRNA linear HUM 30-JUN-2000
DEFINITION Homo sapiens cone photoreceptor cGMP-gated cation channel
beta-subunit (CNGB3) mRNA, complete cds.
ACCESSION AF228520
VERSION AF228520.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2135)
AUTHORS Sundin,O.H., Yang,J.M., Li,Y., Zhu,D., Hurd,J.N., Mitchell,T.N.,
Silva,E.D. and Maumenee,I.H.
TITLE Genetic basis of total colourblindness among the Pingelapese
islanders
JOURNAL Nat. Genet. 25 (3), 289-293 (2000)
PUBMED 10888875
REFERENCE 2 (bases 1 to 2135)
AUTHORS Sundin,O.H., Yang,J.-M., Li,Y., Zhu,D., Silva,E.D. and
Maumenee,I.H.
TITLE Direct Submission
JOURNAL Submitted (25-JAN-2000) Opthalmology, Johns Hopkins School of
Medicine, 600 North Wolfe Street, Baltimore, MD 21287, USA
FEATURES Location/Qualifiers
source 1..2135
/db_xref="H-InvDB:HIT000074499"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="8"
/map="8q21-q22"
/tissue_type="retina"
gene 1..2135
/gene="CNGB3"
CDS 244..2076
/gene="CNGB3"
/note="membrane channel; CNGA3; core channel domain"
/codon_start=1
/product="cone photoreceptor cGMP-gated cation channel
beta-subunit"
/protein_id="AAF80179.1"
/translation="MPLTEYLKRIKLPNSIDSYTDRLYLLWLLLVTLAYNWNCCFIPL
RLVFPYQTADNIHYWLIADIICDIIYLYDMLFIQPRLQFVRGGDIIVDSNELRKHYRT
STKFQLDVASIIPFDICYLFFGFNPMFRANRMLKYTSFFEFNHHLESIMDKAYIYRVI
RTTGYLLFILHINACVYYWASNYEGIGTTRWVYDGEGNEYLRCYYWAVRTLITIGGLP
EPQTLFEIVFQLLNFFSGVFVFSSLIGQMRDVIGAATANQNYFRACMDDTIAYMNNYS
IPKLVQKRVRTWYEYTWDSQRMLDESDLLKTLPTTVQLALAIDVNFSIISKVDLFKGC
DTQMIYDMLLRLKSVLYLPGDFVCKKGEIGKEMYIIKHGEVQVLGGPDGTKVLVTLKA
GSVLLAAGGGNRRTANVVAHGFANLLTLDKKTLQEILVHYPDSERILMKKARVLLKQK
AKTAEATPPRKDLALLFPPKEETPKLFKTLLGGTGKASLARLLKLKREQAAQKKENSE
GGEEEGKENEDKQKENEDKQKENEDKGKENEDKDKGREPEEKPLDRPECTASPIAVEE
EPHSVRRTVLPRGTSRQSLIISMAPSAEGGEEVLTIEVKEKAKQ"
BASE COUNT 701 a 434 c 449 g 551 t
ORIGIN
1 ccacaaaaca aaccgcctgc agctcctgtt ataaatgagt atgccgatgc ccagctacac
61 aacctggtga aaagaatgcg tcaaagaaca gccctctaca agaaaaagtt ggtagaggga
121 gatctctcct cacccgaagc cagcccacaa actgcaaagc ccacggctgt accaccagta
181 aaagaaagcg atgataagcc aacagaacat tactacaggc tgttgtggtt caaagtcaaa
241 aagatgcctt taacagagta cttaaagcga attaaacttc caaacagcat agattcatac
301 acagatcgac tctatctcct gtggctcttg cttgtcactc ttgcctataa ctggaactgc
361 tgttttatac cactgcgcct cgtcttccca tatcaaaccg cagacaacat acactactgg
421 cttattgcgg acatcatatg tgatatcatc tacctttatg atatgctatt tatccagccc
481 agactccagt ttgtaagagg aggagacata atagtggatt caaatgagct aaggaaacac
541 tacaggactt ctacaaaatt tcagttggat gtcgcatcaa taataccatt tgatatttgc
601 tacctcttct ttgggtttaa tccaatgttt agagcaaata ggatgttaaa gtacacttca
661 ttttttgaat ttaatcatca cctagagtct ataatggaca aagcatatat ctacagagtt
721 attcgaacaa ctggatactt gctgtttatt ctgcacatta atgcctgtgt ttattactgg
781 gcttcaaact atgaaggaat tggcactact agatgggtgt atgatgggga aggaaacgag
841 tatctgagat gttattattg ggcagttcga actttaatta ccattggtgg ccttccagaa
901 ccacaaactt tatttgaaat tgtttttcaa ctcttgaatt ttttttctgg agtttttgtg
961 ttctccagtt taattggtca gatgagagat gtgattggag cagctacagc caatcagaac
1021 tacttccgcg cctgcatgga tgacaccatt gcctacatga acaattactc cattcctaaa
1081 cttgtgcaaa agcgagttcg gacttggtat gaatatacat gggactctca aagaatgcta
1141 gatgagtctg atttgcttaa gaccctacca actacggtcc agttagccct cgccattgat
1201 gtgaacttca gcatcatcag caaagtcgac ttgttcaagg gttgtgatac acagatgatt
1261 tatgacatgt tgctaagatt gaaatccgtt ctctatttgc ctggtgactt tgtctgcaaa
1321 aagggagaaa ttggcaagga aatgtatatc atcaagcatg gagaagtcca agttcttgga
1381 ggccctgatg gtactaaagt tctggttact ctgaaagctg ggtcggtcct tctagcagca
1441 ggaggaggaa accgtcgaac tgccaatgtg gtggcccacg ggtttgccaa tcttttaact
1501 ctagacaaaa agaccctcca agaaattcta gtgcattatc cagattctga aaggatcctc
1561 atgaagaaag ccagagtgct tttaaagcag aaggctaaga ccgcagaagc aacccctcca
1621 agaaaagatc ttgccctcct cttcccaccg aaagaagaga cacccaaact gtttaaaact
1681 ctcctaggag gcacaggaaa agcaagtctt gcaagactac tcaaattgaa gcgagagcaa
1741 gcagctcaga agaaagaaaa ttctgaagga ggagaggaag aaggaaaaga aaatgaagat
1801 aaacaaaaag aaaatgaaga taaacaaaaa gaaaatgaag ataaaggaaa agaaaatgaa
1861 gataaagata aaggaagaga gccagaagag aagccactgg acagacctga atgtacagca
1921 agtcctattg cagtggagga agaaccccac tcagttagaa ggacagtttt acccagaggg
1981 acttctcgtc aatcactcat tatcagcatg gctccttctg ctgagggcgg agaagaggtt
2041 cttactattg aagtcaaaga aaaggctaag caataaatgt ttgattatct ttagatgtga
2101 tatagctagt tcccaaagtg attgtaccta ggatt
//