LOCUS AF225971 1830 bp mRNA linear HUM 03-AUG-2000
DEFINITION Homo sapiens gamma-tubulin (TUBG2) mRNA, complete cds.
ACCESSION AF225971
VERSION AF225971.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1830)
AUTHORS Wise,D.O., Krahe,R. and Oakley,B.R.
TITLE The gamma-tubulin gene family in humans
JOURNAL Genomics 67 (2), 164-170 (2000)
PUBMED 10903841
REFERENCE 2 (bases 1 to 1830)
AUTHORS Wise,D.O. and Oakley,B.R.
TITLE Direct Submission
JOURNAL Submitted (17-JAN-2000) Molecular Genetics, Ohio State University,
484 W. 12th Ave., Columbus, OH 43210, USA
FEATURES Location/Qualifiers
source 1..1830
/db_xref="H-InvDB:HIT000074436"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="17"
/map="17q21"
gene 1..1830
/gene="TUBG2"
/note="second functional human gamma-tubulin gene"
CDS 250..1605
/gene="TUBG2"
/note="component of centrosome essential for microtubule
nucleation"
/codon_start=1
/product="gamma-tubulin"
/protein_id="AAF34188.1"
/translation="MPREIITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVEEFATEG
TDRKDVFFYQADDEHYIPRAVLLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGN
NWASGFSQGEKIHEDIFDIIDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLNDR
YPKKLVQTYSVFPYQDEMSDVVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIATDRL
HIQNPSFSQINQLVSTIMSASTTTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPL
TTDQSVASVRKTTVLDVMRRLLQPKNVMVSTGRDRQTNHCYIAILNIIQGEVDPTQVH
KSLQRIRERKLANFIPWGPASIQVALSRKSPYLPSAHRVSGLMMANHTSISSLFESSC
QQFDKLRKRDAFLEQFRKEDMFKDNFDEMDRSREVVQELIDEYHAATQPDYISWGTQE
Q"
variation 648
/gene="TUBG2"
/note="some ESTs contain in-frame insertion; possible
alternative splice"
/db_xref="dbEST:H10668"
/db_xref="dbEST:H10669"
BASE COUNT 416 a 581 c 476 g 357 t
ORIGIN
1 aagcttacga ggaattcttg gatgacatcc ctcagcatgt ctgagcgact gctgagggag
61 aaaatgatgc ccaggttggt ccccggccca ccgcagagag gcctgcgctg cacacgcgca
121 gaccgagcat ccgcgtcaag aggcgaagag agcgcgcgct ccccacgtcc tgcgctcctg
181 gctgccgggc attcgtctca gccgtgactc tcgccaggcc ggggctggcg cgcccacgtc
241 tgaagagcga tgccccggga gatcatcacc ctgcagctgg gccagtgcgg caaccagatt
301 gggttcgagt tctggaaaca gctgtgcgcc gagcatggta tcagccccga gggcatcgtg
361 gaggagttcg ccaccgaggg cactgaccgc aaggacgtct ttttctacca ggcagacgat
421 gagcactaca tcccccgggc cgtgctgctg gacttggaac cccgggtgat ccactccatc
481 ctcaactccc cctatgccaa gctctacaac ccagagaaca tctacctgtc ggaacatgga
541 ggaggagctg gcaacaactg ggccagcgga ttctcccagg gtgagaaaat tcatgaagac
601 atctttgaca tcatagaccg agaagcagat ggaagtgaca gtttggaggg cttcgtgctg
661 tgtcactcca tcgctggggg tacgggttct ggcctgggct cctacctcct ggagcgactg
721 aatgacaggt accccaagaa gctagtgcag acttattcag tgtttcccta ccaggacgag
781 atgagcgacg tagtggttca gccctacaat tcactcctga cactcaagag gctgacgcag
841 aacgcagatt gtgtggtggt gctggacaac acagccctga accggattgc cacagaccgc
901 ctgcacatcc agaacccgtc cttctcccag atcaaccagc tggtgtccac catcatgtcg
961 gccagcacca ccaccctgcg ctaccccggc tacatgaaca atgacctcat cggcctcatc
1021 gcctcgctca ttcccacccc acggctccac tttctcatga ccggctacac cccgctcact
1081 acagaccagt cagtggccag cgtgaggaag accacggtcc tggatgtcat gaggcggctg
1141 ctgcagccca agaacgtgat ggtgtccaca ggccgagacc gccagaccaa ccactgctac
1201 atcgccatcc tcaacatcat ccagggagag gtggacccca cccaggtcca caagagcctg
1261 cagaggatcc gggaacggaa gttggccaac ttcatcccgt ggggccccgc cagcatccag
1321 gtggccctgt cgaggaagtc tccctacctg ccctcggccc accgggtcag cgggctcatg
1381 atggccaacc acaccagcat ctcctcgctc tttgaaagtt cctgccagca gtttgacaag
1441 ctgcggaagc gggatgcctt cctcgagcag ttccgtaagg aggacatgtt caaggacaac
1501 tttgatgaga tggacaggtc tagggaggtt gttcaggagc tcattgatga gtaccatgcg
1561 gccacccagc cagactacat ttcctggggc acccaggagc agtgatttcc ctccccacta
1621 ctccttctcc ttctagatgg taaccacagc ctcgaccatg cctgctccct ctgacccagc
1681 ttcacctcat ggacaaccct tcttggttca tctccagccc gtgagctggt cctgcttcct
1741 cccttccatg ccctaacttt taatatgctt gttcagctct aataaagtaa taaagcttgg
1801 ttgtcagtat aaaaaaaaaa aaaaaaaaaa
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