LOCUS AF221520 2435 bp mRNA linear HUM 26-JUL-2016
DEFINITION Homo sapiens basic helix-loop-helix protein class B 1 (BHLHB1)
mRNA, partial cds.
ACCESSION AF221520
VERSION AF221520.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2435)
AUTHORS Wang,J., Jani-Sait,S.N., Escalon,E.A., Carroll,A.J., de Jong,P.J.,
Kirsch,I.R. and Aplan,P.D.
TITLE The t(14;21)(q11.2;q22) chromosomal translocation associated with
T-cell acute lymphoblastic leukemia activates the BHLHB1 gene
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 97 (7), 3497-3502 (2000)
PUBMED 10737801
REFERENCE 2 (bases 1 to 2435)
AUTHORS Wang,J., Jani-sait,S.N., Escalon,E.A., Carroll,A.J., deJong,P.J.,
Kirsch,I.R. and Aplan,P.D.
TITLE Direct Submission
JOURNAL Submitted (05-JAN-2000) Medicine branch, National Cancer Institute,
8717 Grovemont Circle, Gaithersburg, MD 20877, USA
FEATURES Location/Qualifiers
source 1..2435
/db_xref="H-InvDB:HIT000074365"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene <1..2435
/gene="BHLHB1"
CDS <1..1076
/gene="BHLHB1"
/codon_start=3
/product="basic helix-loop-helix protein class B 1"
/protein_id="AAF61215.1"
/translation="LRLFGASSSNRIQIFGSEGRRTLRKLRRLSSPGAMDSDASLVSS
RPSSPEPDDLFLPARSKGSSGSAFTGGTVSSSTPSDCPPELSAELRGAMGSAGAHPGD
KLGGSGFKSSSSSTSSSTSSAAASSTKKDKKQMTEPELQQLRLKINSRERKRMHDLNI
AMDGLREVMPYAHGPSVRKLSKIATLLLARNYILMLTNSLEEMKRLVSEIYGGHHAGF
HPSACGGLAHSAPLPAATAHPAAAAHAAHHPAVHHPILPPAAAAAAAAAAAAAVSSAS
LPGSGLPSVGSIRPPHGLLKSPSAAAAAPLGGGGGGSGASGGFQHWGGMPCPCSMCQV
PPPHHHVSAMGAGSLPRLTSDAK"
BASE COUNT 465 a 726 c 718 g 526 t
ORIGIN
1 ccctgaggct tttcggagcg agctcctcaa atcgcatcca gattttcggg tccgagggaa
61 ggaggaccct gcgaaagctg cgacgactat cttcccctgg ggccatggac tcggacgcca
121 gcctggtgtc cagccgcccg tcgtcgccag agcccgatga cctttttctg ccggcccgga
181 gtaagggcag cagcggcagc gccttcactg ggggcaccgt gtcctcgtcc accccgagtg
241 actgcccgcc ggagctgagc gccgagctgc gcggcgctat gggctctgcg ggcgcgcatc
301 ctggggacaa gctaggaggc agtggcttca agtcgtcctc gtccagcacc tcgtcgtcta
361 cgtcgtcggc ggctgcgtcg tccaccaaga aggacaagaa gcaaatgaca gagccggagc
421 tgcagcagct gcgtctcaag atcaacagcc gcgagcgcaa gcgcatgcac gacctcaaca
481 tcgccatgga tggcctccgc gaggtcatgc cgtacgcaca cggcccttcg gtgcgcaagc
541 tttccaagat cgccacgctg ctgctggcgc gcaactacat cctcatgctc accaactcgc
601 tggaggagat gaagcgactg gtgagcgaga tctacggggg ccaccacgct ggcttccacc
661 cgtcggcctg cggcggcctg gcgcactccg cgcccctgcc cgccgccacc gcgcacccgg
721 cagcagcagc gcacgccgca catcaccccg cggtgcacca ccccatcctg ccgcccgccg
781 ccgcagcggc tgctgccgcc gctgcagccg cggctgtgtc cagcgcctct ctgcccggat
841 ccgggctgcc gtcggtcggc tccatccgtc caccgcacgg cctactcaag tctccgtctg
901 ctgccgcggc cgccccgctg gggggcgggg gcggcggcag tggggcgagc gggggcttcc
961 agcactgggg cggcatgccc tgcccctgca gcatgtgcca ggtgccgccg ccgcaccacc
1021 acgtgtcggc tatgggcgcc ggcagcctgc cgcgcctcac ctccgacgcc aagtgagccg
1081 actggcgccg gcgcgttctg gcgacagggg agccaggggc cgcggggaag cgaggactgg
1141 cctgcgctgg gctcgggagc tctgtcgcga ggaggggcgc aggaccatgg actgggggtg
1201 gggcatggtg gggattccag catctgcgaa cccaagcaat gggggcgccc acagagcagt
1261 ggggagtgag gggatgttct ctccgggacc tgatcgagcg ctgtctggct ttaacctgag
1321 ctggtccagt agacatcgtt ttatgaaaag gtaccgctgt gtgcattcct cactagaact
1381 catccgaccc ccgaccacca cctccgggaa aagattctaa aaacttcttt ccctgagagc
1441 gtggcctgac ttgcagactc ggcttgggca gcacttcggg gggggagggg gtgttatggg
1501 agggggacac attggggcct tgctcctctt cctcctttct tggcgggtgg gagactccgg
1561 gtagccgcac tgcagaagca acagcccgac cgcgccctcc agggtcgtcc ctggcccaag
1621 gccaggggcc acaagttagt tggaagccgg cgttcggtat cagaagcgct gatggtcata
1681 tccaatctca atatctgggt caatccacac cctcttagaa ctgtggccgt tcctccctgt
1741 ctctcgttga tttgggagaa tatggttttc taataaatct gtggatgttc cttcttcaac
1801 agtatgagca agtttataga cattcagagt agaaccactt gtggattgga ataacccaaa
1861 actgccgatt tcaggggcgg gtgcattgta gttattattt taaaatagaa actaccccac
1921 cgactcatct ttccttctct aagcacaaag tgatttggtt attttggtac ctgagaacgt
1981 aacagaatta aaaggcagtt gctgtggaaa cagtttgggt tatttggggg ttctgttggc
2041 tttttaaaat tttctttttt ggatgtgtaa atttatcaat gatgaggtaa gtgcgcaatg
2101 ctaagctgtt tgctcacgtg actgccagcc ccatcggagt ctaagccggc tttcctctat
2161 tttggtttat ttttgccacg tttaacacaa atggtaaact cctccacgtg cttcctgcgt
2221 tccgtgcaag ccgcctcggc gctgcctgcg ttgcaaactg ggctttgtag cgtctgccgt
2281 gtaacaccct tcctctgatc gcaccgcccc tcgcagagag tgtatcatct gttttatttt
2341 tgtaaaaaca aagtgctaaa taatatttat tacttgtttg gttgcaaaaa cggaataaat
2401 gactgagtgt tgagatttta aataaaattt aaagt
//