LOCUS AF217500 8293 bp mRNA linear HUM 02-JAN-2002
DEFINITION Homo sapiens histone acetyltransferase MOZ2 (MOZ2) mRNA, complete
cds.
ACCESSION AF217500
VERSION AF217500.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 8293)
AUTHORS Borrow,J. and Housman,D.E.
TITLE Structure and function of the human MYST family: MOZ2, MYST1 and
MYST2
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 8293)
AUTHORS Borrow,J. and Housman,D.E.
TITLE Direct Submission
JOURNAL Submitted (20-DEC-1999) Center for Cancer Research, Massachusetts
Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA
02139, USA
FEATURES Location/Qualifiers
source 1..8293
/db_xref="H-InvDB:HIT000074173"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="10"
gene 1..8293
/gene="MOZ2"
/note="monocytic leukemia gene 2"
CDS 489..6707
/gene="MOZ2"
/note="MYST family member; similar to MOZ"
/codon_start=1
/product="histone acetyltransferase MOZ2"
/protein_id="AAL56647.1"
/translation="MVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDK
KTVSEQLELSVQDGSVLKVTNKGLASYKDPDNPGRFSSVKPGTFPKSAKGSRGSCNDL
RNVDWNKLLRRAIEGLEEPNRSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAV
NNGRLLKDGPQYRVNYGSLDGKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSF
CLGTKESNREKKAEELLSCADCGSSGHPSCLKFCPELTTNVKALRWQCIECKTCSACR
VQGRNADNMLFCDSCDRGFHMECCDPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQI
KRRYAKPIGRPKNKLKQRLLSVTSDEGSMNAFTGRGSPGRGQKTKVCTTPSSGHAASG
KDSSSRLAVTDPTRPGATTKITTTSTYISASTLKVNKKTKGLIDGLTKFFTPSPDGRR
SRGEIIDFSKHYRPRKKVSQKQSCTSHVLATGTTQKLKPPPSSLPPPTPISGQSPSSQ
KSSTATSSPSPQSSSSQCSVPSLSSLTTNSQLKALFDGLSHIYTTQGQSRKKGHPSYA
PPKRMRRKTELSSTXKSKAHFFGKRDIRSRFISHSSSSSWGMARGSIFKAIAHFKRTT
FLKKHRMLGRLKYKVTPQMGTPSPGKGSLTDGRIKPDQDDDTEIKINIKQESADVNVI
GNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCGRYPSVIEFGKYEIQTWYSSPYPQ
EYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANEIYRRKDLSVFEVDGNMSK
IYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTKNDEKGCHLVGYFSKEKLCQQKYNVS
CIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSPEKPLSDLGRLSYLAYWKSVILEYL
YHHHERHISIKAISRARHVPHDIATTLQHLHMIDKRDGRFVIIRREKLILSHMEKLKT
CSRANELDPDSLRWTPILISNAAVSEEEREAEKEAERLMEQASCWEKEEQEILSTRAN
SRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEE
DEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLKKKRGRKRRRINSSVTTE
TISESTEVLNXPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLRKAFQHQPGKKRQTEE
EEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQVWPKGTKRGLSKWRQNK
ERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLPQ
EENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVE
KDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESA
EVEKEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPKELAGD
PEAVPESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPATMEIDSETVQAVQSLTQESS
EQDDTFQDCAETQEACRSLQNYTRADQSPQIATTLDDCQQSDHSSPVSSVHSHPGQSV
RSVNSPSVPALENTYAQISPDQSAISVPSLQNMETSPMMDVPSVSDHSQQVVDSGFSD
LGSIESTTENYENPSSYDSTMGGSICGNGSSQNSCSYSNLTSSSLTQSSCAVTQQMSN
ISGTCSMLQQTSISSPPTCSVKSPQGCVVERPPSSSQQLAQCSMAANFTPPMQLAEIP
ETSNANIGLYERMGQSDFGAGHYPQPSATFSLAKLQQLTNTLIDHSLPYSHSAAVTSY
ANSASLSTPLSNTGLVQLSQSPHSVPGGPQAQATMTPPPNLTPPPMNLPPPLLQRNMA
ASNIGISHSQRLQTQIASKGHISMRTKSASLSPAAATHQSQIYGRSQTVAMQGPARTL
TMQRGMNMSVNLMPAPAYNVNSVNMNMNTLNAMNGYSMSQPMMNSGYHSNHGYMNQTP
QYPMQMQMGMMGTQPYAQQPMQTPPHGNMMYTAPGHHGYMNTGMSKQSLNGSYMRR"
BASE COUNT 2578 a 1864 c 1884 g 1965 t
ORIGIN
1 gacaacaaca gggggacaca aaatggcggc ggcttagctc ctacccctgg cggcggcggc
61 agcggtggcg gaggcgacgg cacctcctcc aggcggcagc cgcagtttct caggcagcgg
121 cagccccccg gcaggcgcgg tggcggtggc gcgcagccag atttgcctga agacctggat
181 aatctccatt tttgtcatgg actgttaaaa cgtttgaagt tccaattctg gtcttgattt
241 cccagttaaa gatgttcttc acccgaatgc agtctttcct gttggtaaaa taagacaacc
301 atcaacattg cctgtttgtc tgcttttgaa tctcttaagg atggatgttt gtaagatgtt
361 gcttaataca gtctggaata ctctgtccat ttgttgaatt gtaaatgact ttcaaatgtg
421 caagttctgt taaatacaaa gagaacctct atgggtaact tttgtgttga agaagtcatt
481 tgtcaaccat ggtaaaactt gcaaacccac tttatacaga gtggattctt gaagctatac
541 agaaaataaa aaagcaaaag caaaggccct ctgaagagag aatctgccat gcggtcagta
601 cttcccatgg gttggataag aagacagtct ctgaacagct ggaactcagt gttcaggatg
661 gctcagttct caaagtcacc aacaaaggcc ttgcctccta taaggaccca gacaaccctg
721 ggcgcttttc atcagttaaa ccaggcactt ttcctaagtc agccaagggg tctagaggat
781 catgtaatga tctccgcaat gtggattgga ataaactttt aaggagagca attgaaggac
841 ttgaggagcc gaatcgctcc tccctgaaga acatagagaa gtatctcaga agtcaaagtg
901 atctcacaag caccaccaac aacccagcct ttcagcagcg gctgcgactg ggggccaaac
961 gcgctgtgaa taatgggagg ttactgaaag acggaccgca gtacagggtc aattatggga
1021 gcttagatgg caaaggggca cctcagtatc ccagtgcatt cccatcctcg ctcccacctg
1081 tcagccttct accccatgag aaagaccagc cccgtgctga tcccattcca atatgtagct
1141 tctgtttggg gactaaagaa tcaaatcgtg aaaagaaagc agaagaactc ctctcttgtg
1201 cagattgtgg cagtagtgga cacccatcct gtttgaaatt ttgtcctgaa ttaacaacaa
1261 atgtaaaggc cttaaggtgg cagtgcatcg aatgcaagac atgcagtgcc tgtagagtcc
1321 aaggcagaaa tgctgataat atgctttttt gtgattcctg tgatagagga tttcatatgg
1381 aatgctgtga cccaccactt tccagaatgc caaaagggat gtggatttgc caagtctgca
1441 gaccaaagaa aaagggaaga aaactacttc atgagaaagc tgcacaaata aaacgacgat
1501 atgcaaaacc cattggacga ccgaaaaata aattaaagca acgattgttg tctgtaacca
1561 gtgatgaagg atccatgaat gcattcacag gaagggggtc acctggtagg ggtcaaaaga
1621 ctaaagtctg taccacacct tcatctggtc atgctgcatc tgggaaggac tcaagcagca
1681 gattggctgt tacagacccc actcggcctg gtgccaccac caaaatcacc accacctcca
1741 cctacatttc tgcctctaca cttaaagtta acaagaaaac caaagggctc attgatggcc
1801 ttactaagtt ttttacacca tcacctgatg gtcgcagatc acgaggtgaa attatagact
1861 tttcaaagca ctatcgtcca aggaaaaagg tctctcagaa acagtcatgc acttctcatg
1921 tgttggctac aggtaccaca caaaagctaa aacctccacc ttcttcactt ccacccccaa
1981 cccccatctc cggtcagagc cccagttcac aaaagtccag cacggccact tcttctccct
2041 ctccccagag ttcttccagc cagtgcagtg tgccctccct gagcagcctt accactaaca
2101 gccagctgaa ggcactcttt gatgggcttt ctcatatcta taccactcag ggacagtctc
2161 gcaaaaaggg acacccgagt tatgcaccac ccaaacgtat gcgtcgtaaa actgaattat
2221 cttccacggn aaaatctaaa gcccacttct ttggcaaaag agatattaga agtcggttta
2281 tttctcactc ctcctcctct agctggggga tggctagagg aagtattttt aaagcaattg
2341 ctcacttcaa gcgaacaact ttccttaaaa agcacaggat gctaggcaga ttaaaatata
2401 aagtgacccc tcagatgggg accccctcac cagggaaggg gagcttgaca gacggaagga
2461 ttaaacctga tcaggatgat gatactgaaa taaaaataaa catcaaacaa gaaagtgcag
2521 atgtaaatgt gattggaaac aaggatgtcg ttactgaaga ggatttggat gtttttaagc
2581 aggcccagga actttcttgg gagaaaatag agtgtgagag tggggtggaa gactgtggcc
2641 ggtacccttc tgtgattgaa tttggtaaat atgaaatcca aacctggtac tcctcgcctt
2701 acccacagga atatgcaaga ttaccaaagc tttacctgtg tgaattctgt cttaaatata
2761 tgaaaagtaa aaatattttg ctaagacact ccaagaagtg tggatggttt catcctccag
2821 caaatgaaat ttaccgaagg aaagaccttt cagtatttga ggttgatggg aatatgagca
2881 aaatttattg ccaaaacctt tgcttgttag ccaagctctt cctggaccac aaaacgttgt
2941 attatgatgt cgagccattc cttttttatg tccttacaaa aaatgatgaa aagggctgtc
3001 atctggttgg atacttctct aaggaaaagc tttgccagca gaagtataat gtctcctgca
3061 taatgatcat gccccagcac caaaggcaag gatttggacg gtttctcatt gatttcagct
3121 atttgctttc tagaagagaa ggccaagcag ggtctcctga aaagcctctc tccgatctgg
3181 gccgtctctc ctacctggca tattggaaga gcgtcatctt ggagtatctc taccaccacc
3241 atgagaggca catcagcatc aaggcaatta gcagagcacg gcatgtgcca catgacattg
3301 ccaccactct gcagcacctc cacatgatcg acaagagaga tggcagattt gtcatcatta
3361 gacgggaaaa gttgatattg agccacatgg aaaagctgaa aacctgttcc agagccaatg
3421 aacttgatcc agacagtctg aggtggaccc caattttaat ttctaatgct gcagtgtctg
3481 aagaagagcg agaagctgag aaagaggctg agcggctaat ggaacaagct agctgctggg
3541 agaaggagga acaagaaatc ctgtcaacta gagctaacag taggcaatca cctgcaaaag
3601 tacaatcgaa aaataaatat ttgcattccc cggagagccg gccagtcaca ggggagcgag
3661 ggcagctgct ggagctgtct aaagagagca gtgaagaaga agaggaggag gaggacgagg
3721 aggaggaaga agaggaggaa gaagaggaag aggatgaaga ggaggaagaa gaggaagaag
3781 aagaagaaga agaagaaaat attcaaagct ctcccccaag attgacgaaa ccacagtcag
3841 ttgccataaa gagaaagagg ccttttgtac taaagaagaa aaggggtcgt aaacgcagga
3901 ggatcaacag cagtgtaaca acagagacca tttcagagag cacagaagta ctgaatnagc
3961 cctttgacaa ctcagatgaa gagaggccaa tgccacagct ggagcctacc tgtgagattg
4021 aagtggagga agatggcagg aagccagtcc tgagaaaagc attccagcat cagcctggga
4081 agaaaagaca aacagaggaa gaggaaggaa aagacaatca ttgcttcaag aatgctgacc
4141 cttgtagaaa caatatgaat gatgattcaa gtaacttgaa agaaggcagt aaagacaatc
4201 ccgaacctct aaagtgcaaa caagtgtggc caaaaggaac aaagcgcggt ctatctaagt
4261 ggaggcaaaa caaagagagg aagaccggat ttaaactgaa tttgtacacc ccgccagaaa
4321 cacccatgga gcctgacgag caggtaacag tggaagaaca gaaggagact tcagaaggaa
4381 aaaccagccc cagtcccatc aggattgagg aggaggtcaa ggaaactggg gaagccctgt
4441 tgcctcaaga ggaaaacaga agggaagaaa catgtgcccc tgtaagtcca aacacatcac
4501 caggtgaaaa accagaagat gatctcatca aacctgagga agaggaagag gaggaggagg
4561 aggaagagga agaagaggaa gaagaggaag gggaagaaga agaaggagga ggaaatgtag
4621 aaaaagatcc agatggtgct aaaagccaag aaaaagagga accagaaatc tccacggaaa
4681 aagaagactc tgcacgtttg gatgatcacg aagaggagga ggaagaggat gaagagccat
4741 cccacaacga ggaccatgat gccgatgacg aggatgacag ccacatggag tctgccgaag
4801 tggagaagga agagctgccc agagaaagct tcaaagaagt actggaaaac caggagactt
4861 ttttagacct taatgtgcag cctggtcact cgaacccaga ggtcttaatg gactgtggcg
4921 tcgacctgac agcttcttgt aacagtgagc ccaaggagct tgctggggac cctgaagctg
4981 tacccgaatc tgacgaggag ccacccccag gagaacaggc acagaagcag gaccaaaaga
5041 acagcaagga agtcgataca gagttcaaag agggaaaccc agcaaccatg gaaatcgact
5101 ctgagactgt ccaggccgtt cagtctttga cccaggagag cagcgaacag gacgacacct
5161 ttcaggattg tgccgagact caagaggcct gtagaagcct acagaactac acccgtgcag
5221 accaaagtcc acagattgcc accacgctcg acgattgcca acagtcggac cacagtagcc
5281 cagtttcatc cgtccactcc catcctggcc agtccgtacg ttctgtcaac agcccaagtg
5341 tccctgctct ggaaaacacg tacgcccaaa tcagcccaga tcaaagtgcc atctcagtgc
5401 catctctgca gaacatggaa accagtccca tgatggatgt cccatcagtt tcagatcatt
5461 cacagcaagt cgtagacagt ggatttagtg acctgggcag tatcgagagc acaactgaga
5521 actacgaaaa cccaagcagc tacgattcta ctatgggagg cagcatctgt ggaaacggct
5581 cttcacagaa cagctgctcc tatagcaacc tcacctccag cagtctgaca cagagcagct
5641 gtgctgtcac ccagcagatg tccaacatca gcgggacgtg cagcatgctg cagcaaacca
5701 gcatcagctc ccctccgacc tgcagcgtca agtctcctca aggctgtgtg gtggagaggc
5761 ctccgagcag cagccagcag ctggctcagt gcagcatggc tgctaacttc accccaccca
5821 tgcagctggc tgaaatcccc gagacgagca acgccaacat tggcttatac gagcgaatgg
5881 gtcagagtga ttttggggct gggcattacc cgcagccgtc agccaccttc agccttgcca
5941 aactgcagca gttaactaat acacttattg atcattcatt gccttacagc cattccgctg
6001 ctgtgacttc ctatgcaaac agtgcctctt tgtccacacc attaagtaac acagggcttg
6061 ttcaactttc tcagtctcca cactccgtcc ctgggggacc ccaagcacaa gctaccatga
6121 ccccaccccc caacctgact cctcctccaa tgaatctgcc gccgcctctt ttgcaacgga
6181 acatggctgc atcaaatatt ggcatctctc acagccaaag actgcaaacc cagattgcca
6241 gcaagggcca catctccatg agaaccaagt cagcgtctct gtcaccagcc gctgccaccc
6301 atcagtcaca aatctatggg cgctcccaga ctgtagccat gcagggtcct gcacggactt
6361 taacgatgca aagaggcatg aacatgagtg tgaacctgat gccagcgcca gcctacaatg
6421 tcaactctgt gaacatgaac atgaacactc tcaacgccat gaatgggtac agcatgtccc
6481 agccaatgat gaacagtggc taccacagca atcatggcta tatgaatcaa acgccccaat
6541 accctatgca gatgcagatg ggcatgatgg gcacccagcc atatgcccag cagccaatgc
6601 agaccccacc ccacggtaac atgatgtaca cggcccccgg acatcacggc tacatgaaca
6661 caggcatgtc caaacagtct ctcaatggct cctacatgag aaggtagaca acgtgggcag
6721 tccacaaaac ctacggggca tcactattgg attgatctgc acaaatacct ttgaagagta
6781 cgatttcaaa accagcaatt ggtgtgaatg caaaaacatt tgttggcacc atttatttaa
6841 aaaaaaaaaa agctgtatgc agcagaaagc cttatacaag ttgtttttct ttttttcctt
6901 tttctttttt ttggtacctt catttctgtt acttttatat aaaattctct gcaaaggaag
6961 gcctctcttt ggactacaat ttggaggcag ccacttgttg tgcctgcttc tgttaaacaa
7021 tgtggatatc aagccccccc aaattatctg ttttaatatt gaacctagag cttttttttt
7081 cccttccctg tccactccat gtaaatgcct ttagcatttc agttattgta tattttgttt
7141 aaggtgacac ttcagcatgc cgctaatgtc tttgttagtg acagtgcatt ttgtagtact
7201 gtacaagtgt tgtgctaaca gtaagccatt tcttaagttt tttgccttga ttagggtgcc
7261 ctaatttgag ggttttaaaa aaaactatat ttttgttaat tataaaactg taaagagcta
7321 taaaagctat tcccatttgg ttagtcaaaa gggttttatt gctaaatgtt tggtgtaaag
7381 ttgagaccct tttccatttt ggtgacagat ttctttgggg aaaaaaggca gctttctgtt
7441 ttataaatgc agacttctgt ttattgaatg aagcatatct cagtgtttat ctgtcaggtt
7501 ttgaaacatt tcatatatgt ccaaatactt ggcaggattt aaaaaaaaat agtgaatttg
7561 gtgtaaagtt gctattttat ggaaatgcct ctaactttac attttcattc catctgtaga
7621 tttttctatc tttataaaat attggagtta ttttttaagg aaaaatagaa aagtagcttg
7681 tgaatagctc aaactaagct tacaaatcgc atgtaaaaaa gcaaaaaagt tatttgtgtc
7741 tgtttatatt gcttcctttt ttgtagcctt tgtacctgta cagggtgaca gtaagggcca
7801 agcaggagag gcgtaatcct tgtataaaat aggatccagc gacactcttg tatttatctg
7861 ttctcttttt agtcagtcac ttcaaaaaaa caaaaaacaa acaaaaaaaa gctgtacatt
7921 ttaacataaa ataaattatg atgagccatt tttagcctct tgtgtcctgt catattatga
7981 ttgatagaga atgaccaatg gaactgtatc atgtgtcacg cctcagaaca catacacatt
8041 ttgggaaaat aaattattta gtgtaaattg gagttatggg attttctgat ttgttttgac
8101 tttgggggag gggttggcaa taaataagag taatatctaa taaaaccatc acatatacca
8161 aatacctatt taataaatta atttataatg gattttaatg cttttcatga aagtttattt
8221 tatgcgagtg cataccttct gtatgccaat cattgtcttt aaaataaagt gaaattgttt
8281 tttaaaaaaa aaa
//