LOCUS AF214114 5804 bp mRNA linear HUM 05-APR-2002
DEFINITION Homo sapiens retinoblastoma-binding protein 1-like 1 (RBBP1L1)
mRNA, complete cds.
ACCESSION AF214114 AF335184
VERSION AF214114.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5804)
AUTHORS Cao,J., Gao,T., Giuliano,A.E. and Irie,R.F.
TITLE Recognition of an epitope of a breast cancer antigen by human
antibody
JOURNAL Breast Cancer Res. Treat. 53 (3), 279-290 (1999)
PUBMED 10369074
REFERENCE 2 (bases 1 to 5804)
AUTHORS Cao,J., Gao,T., Stanbridge,E.J. and Irie,R.
TITLE RBP1L1, a retinoblastoma-binding protein-related gene encoding an
antigenic epitope abundantly expressed in human carcinomas and
normal testis
JOURNAL J. Natl. Cancer Inst. 93 (15), 1159-1165 (2001)
PUBMED 11481388
REFERENCE 3 (bases 1 to 5804)
AUTHORS Cao,J.-N., Gao,T.-W., Stanbridge,E.J. and Irie,R.F.
TITLE Direct Submission
JOURNAL Submitted (09-DEC-1999) Department of Biotechnology Sciences, John
Wayne Cancer Institute, 2200 Santa Monica Blvd., Santa Monica, CA
90404, USA
REFERENCE 4 (bases 1 to 5804)
AUTHORS Cao,J.-N., Irie,R.F., Gao,T.-W. and Stanbridge,E.J.
TITLE Direct Submission
JOURNAL Submitted (10-JAN-2001) Microbiology and Molecular Genetics,
University of California Irvine, Irvine, CA 92697-4025, USA
REMARK Sequence update by submitter
COMMENT On Apr 16, 2001 this sequence version replaced AF214114.1.
FEATURES Location/Qualifiers
source 1..5804
/db_xref="H-InvDB:HIT000074113"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="MCF-7"
/note="cloned from cDNA library using an IgG antibody from
a breast cancer patient"
gene 1..5804
/gene="RBBP1L1"
CDS 465..4145
/gene="RBBP1L1"
/codon_start=1
/product="retinoblastoma-binding protein 1-like 1"
/protein_id="AAF28341.2"
/translation="MKALDEPPYLTVGTDVSAKYRGAFCEAKIKTAKRLVKVKVTFRH
DSSTVEVQDDHIKGPLKVGAIVEVKNLDGAYQEAVINKLTDASWYTVVFDDGDEKTLR
RSSLCLKGERHFAESETLDQLPLTNPEHFGTPVIGKKTNRGRRSNHIPEEESSSSSSD
EDEDDRKQIDELLGKVVCVDYISLDKKKALWFPALVVCPDCSDEIAVKKDNILVRSFK
DGKFTSVPRKDVHEITSDTAPKPDAVLKQAFEQALEFHKSRTIPANWKTELKEDSSSS
EAEEEEEEEDDEKEKEDNSSEEEEEIEPFPEERENFLQQLYKFMEDRGTPINKQPVLG
YRNLNLFKLFRLVHKLGGFDNIESGAVWKQVYQDLGIPVLNSAAGYNVKCAYKKYLYG
FEEYCRSANIEFQMALPEKVVNKQCKECENVKEIKVKEENETEIKEIKMEEERNIIPR
EEKPIEDEIERKENIKPSLGSKKNLLESIPTHSDQEKEVNIKKPEDNENLDDKDDDTT
RVDESLNIKVEAEEEKAKSGYDEWIKADKIVRPADKNVPKIKHRKKIKNKLDKEKDKD
EKYSPKNCKLRRLSKPPFQTNPSPEMVSKLDLTDAKNSDTAHIKSIEITSILNGLQAS
ESSAEDSEQEDERGAQDMDNNGKEESKIDHLTNNRNDLISKEEQNSSSLLEENKVHAD
LVISKPVSKSPERLRKDIEVLSEDTDYEEDEVTKKRKDVKKDTTDKSSKPQIKRGKRR
YCNTEECLKTGSPGKKEEKAKNKESLCMENSSNSSSDEDEEETKAKMTPTKKYNGLEE
KRKSLRTTGFYSGFSEVAEKRIKLLNNSDERLQNSRAKDRKDVWSSIQGQWPKKTLKE
LFSDSDTEAAASPPHPAPEEGVAEESLQTVAEEESCSPSVELEKPPPVNVDSKPIEEE
TVEVNDRKAEFPSSGSNSVLNTPPTTPESPSSVTVTEGSRQQSSVTVSEPLAPNQEEV
RSIKSETDSTIEVDSVAGELQDLQSEGNSSPAGFDASVSSSSSNQPEPEHPEKACTGQ
KRVKDAQGGGSSSKKQKRSHKATVVNNKKKGKGTNSSDSEELSAGESITKSQPVKSVS
TGMKSHSTKSPARTQSPGKCGKNGDKDPDLKEPSNRLPKVYKWSFQMSDLENMTSAER
ITILQEKLQEIRKHYLSLKSEVASIDRRRKRLKKKERESAATSSSSSSPSSSSITAAA
MLTLAEPSMSSASQNGMSVECR"
BASE COUNT 2037 a 994 c 1271 g 1502 t
ORIGIN
1 agcgatgttt gcccgtcagt cgagtccgga gtgaggagct cggtcgccga agcggaggga
61 gactcttgag cttcatcttg ccgccgccac ggccaccgcc tggacctttg cccggaggga
121 gctgcagagg gtccatcgcc gccgtcctct ggagggcagc gcgattgggg gcccggacct
181 ccagtccggg ggggattttt cgtcgtcccc ctccccccaa ccagggagcc cgagcggccg
241 ccaaacaaag gtaccagtcg ccgccgcggg aggaggagga gccggagcct ctgcctcaca
301 gccgctggac ccgccgcctt cttccccatc tctcccccgg gcctgctggt tttggggggg
361 agaaggagag aggggactct ggacgtgcca gggtcaaatc tcgcctccga ggaaggtgca
421 actgaacctg gtgttttaaa ggataccttg gtcccaaagt catcatgaag gcccttgatg
481 agcctcccta tttgacagtg ggcactgatg tgagtgctaa atacagagga gccttttgtg
541 aagccaagat caagacagca aaaagacttg tcaaagtcaa ggtgacattt agacatgatt
601 cttcaacagt ggaagttcag gatgaccaca taaagggccc actaaaggta ggagctattg
661 tggaagtgaa gaatcttgat ggtgcatatc aggaagctgt tatcaataaa ctaacagatg
721 cgagttggta cactgtagtt tttgatgacg gagatgagaa gacactgaga cgatcttcac
781 tgtgcctgaa aggagagagg cattttgccg aaagtgaaac attagaccag ctcccactca
841 ccaaccctga gcattttggc actccagtca taggaaagaa aacaaataga ggaagaagat
901 ctaatcatat accagaggaa gagtcttcat catcctccag tgatgaagat gaggatgata
961 ggaaacagat tgatgagcta ctaggcaaag ttgtatgtgt agattacatt agtttggata
1021 aaaagaaagc actgtggttt cctgcattgg tggtttgtcc tgattgtagt gatgagattg
1081 ctgtaaaaaa ggacaatatt cttgttcgat ctttcaaaga tggaaaattt acttcagttc
1141 caagaaaaga tgtccatgaa attactagtg acactgcacc aaagcctgat gctgttttaa
1201 agcaagcctt tgaacaggca cttgaatttc acaaaagtag aactattcct gctaactgga
1261 agactgaatt gaaagaagat agctctagca gtgaagcaga ggaagaagag gaggaggaag
1321 atgatgaaaa agaaaaggag gataatagca gtgaagaaga agaagaaata gaaccatttc
1381 cagaagaaag ggagaacttt cttcagcaat tgtacaaatt tatggaagat agaggtacac
1441 ctattaacaa acaacctgta cttggatatc gaaatttgaa tctctttaag ttattcagac
1501 ttgtacacaa acttggagga tttgataata ttgaaagtgg agctgtttgg aaacaagtct
1561 accaagatct tggaatccct gtcttaaatt cagctgcagg atacaatgtt aaatgtgctt
1621 ataaaaaata cttatatggt tttgaggagt actgtagatc agccaacatt gaatttcaga
1681 tggcattgcc agagaaagtt gttaacaagc aatgtaagga gtgtgaaaat gtaaaagaaa
1741 taaaagttaa ggaggaaaat gaaacagaga tcaaagaaat aaagatggag gaggagagga
1801 atataatacc aagagaagaa aagcctattg aggatgaaat tgaaagaaaa gaaaatatta
1861 agccctctct gggaagtaaa aagaatttat tagaatctat acctacacat tctgatcagg
1921 aaaaagaagt taacattaaa aaaccagaag acaatgaaaa tctggatgac aaagatgatg
1981 acacaactag ggtagatgaa tccctcaaca taaaggtaga agctgaggaa gaaaaagcaa
2041 aatctggata cgatgaatgg attaaagcag ataaaatagt aagacctgct gataaaaatg
2101 tgccaaagat aaaacatcgg aagaaaataa agaataaatt agacaaagaa aaagacaaag
2161 atgaaaaata ctctccaaaa aactgtaaac ttcggcgctt gtccaaacca ccatttcaga
2221 caaatccatc tcctgaaatg gtatccaaac tggatctcac tgatgccaaa aactctgata
2281 ctgctcatat taagtccata gaaattactt cgatccttaa tggacttcaa gcttctgaaa
2341 gttctgctga agacagtgag caggaagatg agagaggtgc tcaagacatg gataataatg
2401 gcaaagaaga atctaagatt gatcatttga ccaacaacag aaatgatctt atttcaaagg
2461 aggaacagaa cagttcatct ttgctagaag aaaacaaagt tcatgcagat ttggtaatat
2521 ccaaaccagt gtcaaaatct ccagaaagat taaggaaaga tatagaagta ttatccgaag
2581 atactgatta tgaagaagat gaagtcacaa aaaagagaaa ggatgtcaag aaggacacaa
2641 cagataaatc ttcaaaacca caaataaaac gtggtaaaag aaggtattgc aatacagaag
2701 agtgtctaaa aactggatca cctggcaaaa aggaagagaa ggccaagaac aaagaatcac
2761 tttgcatgga aaacagtagc aacagctctt cagatgaaga tgaagaagaa acaaaagcaa
2821 agatgacacc aactaagaaa tacaatggtt tggaggaaaa aagaaaatct ctacggacaa
2881 ctggtttcta ttcaggattt tcagaagtgg cagaaaaaag gattaaactt ttaaataact
2941 ctgatgaaag acttcaaaac agcagggcca aagatcgaaa agatgtctgg tcaagtattc
3001 agggacagtg gcctaaaaaa acgctgaaag agcttttttc agactctgat actgaggctg
3061 cagcttcccc accgcatcct gccccagagg agggggtggc agaggagtca ctgcagactg
3121 tggctgaaga ggagagttgt tcacccagtg tagaactaga aaaaccacct ccagtcaatg
3181 tcgatagtaa acccattgaa gaagaaacag tagaggtcaa tgacagaaaa gcagaatttc
3241 caagtagtgg cagtaattca gtgctaaata cccctcctac tacacctgaa tcgccttcat
3301 cagtcactgt aacagaaggc agccggcagc agtcttctgt aacagtatca gaaccactgg
3361 ctccaaacca agaagaggtt cgaagtatca agagtgaaac tgatagcaca attgaggtgg
3421 atagtgttgc tggggagctc caagacctcc agtctgaagg gaatagctcg ccagcaggtt
3481 ttgatgccag tgtgagctca agcagtagta atcagccaga accagaacat cctgaaaaag
3541 cctgtacagg tcagaaaaga gtgaaagatg ctcagggagg aggaagttca tcaaaaaagc
3601 agaaaagaag ccataaagca acagtggtaa acaacaaaaa gaagggaaaa ggcacaaata
3661 gtagtgatag tgaagaactt tcagctggtg aaagtataac taagagtcag ccagtcaaat
3721 cagtttccac tggaatgaag tctcatagta ccaaatctcc cgcaaggacg cagtctccag
3781 gaaaatgtgg aaagaatggt gataaggatc ctgatctcaa ggaacccagt aatcgattac
3841 ccaaagttta caaatggagt tttcagatgt cggacctgga aaatatgaca agtgccgaac
3901 gcatcacaat tcttcaagaa aaacttcaag aaatcagaaa acattatctg tcattaaaat
3961 ctgaagtagc ttccattgat cggaggagaa agcgtttaaa gaagaaagag agagaaagtg
4021 ctgctacatc ctcatcctcc tcttcacctt catccagctc cataacagct gctgctatgt
4081 taactttagc tgaaccgtca atgtccagcg catcacaaaa tggaatgtca gttgagtgca
4141 ggtgacagca ggacttgcta aggcactttg cacttaatgg ctgttgaggg ccactttttt
4201 tttatactgc acagtggcac aaaaaaatat cagacaagca ctattttata tttaaaaatt
4261 gtttcttgac aagccgactt ggcacttaag tgcacttttg tatgaagaaa agtacaatga
4321 actgcttttc ctcaagcaat aattgtttcc aacttgtctg ggaattgtgt gtctggtaac
4381 tggaaggcct tccactgtgg caaatggagg cttctcactg cctgtagaga caatacagta
4441 agcatagtta aggggtgggt cagaacatgt taagataact tactgtatat gtattccctt
4501 gtattttgtt aaagctggaa catttgatat ttttccattt atttatgaaa aaatatgaac
4561 ctattttcat ttgtacaagg taattgtttt ttaaagcaag tcaccttagg gtggctttaa
4621 ttgtataagt caagcacatg taataaattc aaaacctgca gttaacagga tattagacat
4681 taatcctggt aaccaaatat taaagattct ctttaaaaaa gactgaacat gtttacaggt
4741 ttgaattagg ctaaaaggtc ttgcagtggc ttttcatggc ccttcaaatt ggaatggaac
4801 tactgtactt tgccattttt ctataaatca gtattttttt ttaattttga tatacattgt
4861 gtgaaaaaag aaaatggcta ataaactgta ttaaatctta aacaatgtat aaagattgta
4921 cttagccagt tcaaaggtat atttattcat aatgaattat aacagttata tttttgtgtt
4981 ttcttgtaaa tgtttctttt cccttaaata cagataattc atttgtattg cttattttat
5041 tatgagctac aacaaaagga cttcaggaac aagtaatgta ttagtatggt tcaagattgt
5101 tgataggaac tgtctcaaaa ggatggtggt tattttaaat ataaatagct aatgggggtg
5161 gtaggcctat aaaattaaat gccttgtata agatccaaaa tgaatgcaaa attgttttca
5221 cttgtattga ctttatgttg tatgattcca atctctgttc tgtttggcac ttgtatttaa
5281 ttcttcacct ttgtaagaca tttgtatatt gtggatgtgt tcattcaagc tatttaatat
5341 ctggcactgt taatacacag tactttattg tacagactgt tttactgttt taattgtagt
5401 tctgtgtact ttttttggat ggggctggca tgttttcttt gtttcctggc aatacgacgt
5461 gggaatttca atgcgttttg ttgtagatgc taacgtgtca gaatccttta cattcaactt
5521 ttctaagaaa agcattttca gtcttgtagt gtgtgcttac agtaactaat tttgttgaaa
5581 atggtttcaa gttattcaaa tttgtacagg actgtaaaga tttgttgaca gcaaaatgtt
5641 gaagaaaaaa gcttatagaa taaaagctat aaagtatata ttaggatctg caaacaatga
5701 agaattatgt aatatattgt acaaatgtaa agcaaaggct ttgaaataaa atgccattgt
5761 ttgtgaatcc ttaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaa
//