LOCUS AF213460 2546 bp mRNA linear HUM 23-MAR-2001
DEFINITION Homo sapiens ephrin receptor EPHA3 secreted form (EPHA3) mRNA,
complete cds.
ACCESSION AF213460
VERSION AF213460.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2546)
AUTHORS Chiari,R., Hames,G., Stroobant,V., Texier,C., Maillere,B., Boon,T.
and Coulie,P.G.
TITLE Identification of a tumor-specific shared antigen derived from an
Eph receptor and presented to CD4 T cells on HLA class II molecules
JOURNAL Cancer Res. 60 (17), 4855-4863 (2000)
PUBMED 10987298
REFERENCE 2 (bases 1 to 2546)
AUTHORS Chiari,R., Hames,G. and Coulie,P.G.
TITLE Direct Submission
JOURNAL Submitted (08-DEC-1999) Cellular Genetics Unit, Universite
Catholique de Louvain, 74 avenue Hippocrate, Brussels B-1200,
Belgium
FEATURES Location/Qualifiers
source 1..2546
/db_xref="H-InvDB:HIT000074099"
/organism="Homo sapiens"
/mol_type="mRNA"
/isolate="patient LB33"
/db_xref="taxon:9606"
/cell_line="MEL.A-1"
/tissue_type="melanoma"
gene 1..2546
/gene="EPHA3"
CDS 88..1707
/gene="EPHA3"
/note="soluble receptor"
/codon_start=1
/product="ephrin receptor EPHA3 secreted form"
/protein_id="AAG43577.1"
/translation="MDCQLSILLLLSCSVLDSFGELIPQPSNEVNLLDSKTIQGELGW
ISYPSHGWEEISGVDEHYTPIRTYQVCNVMDHSQNNWLRTNWVPRNSAQKIYVELKFT
LRDCNSIPLVLGTCKETFNLYYMESDDDHGVKFREHQFTKIDTIAADESFTQMDLGDR
ILKLNTEIREVGPVNKKGFYLAFQDVGACVALVSVRVYFKKCPFTVKNLAMFPDTVPM
DSQSLVEVRGSCVNNSKEEDPPRMYCSTEGEWLVPIGKCSCNAGYEERGFMCQACRPG
FYKALDGNMKCAKCPPHSSTQEDGSMNCRCENNYFRADKDPPSMACTRPPSSPRNVIS
NINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNT
TVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSR
NSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDTIYVFQ
IRARTAAGYGTNSRKFEFETSPDCMYYFNAV"
BASE COUNT 712 a 557 c 535 g 742 t
ORIGIN
1 cttctccagc aatcagagcg ctccccctca catcagtggc atgcttcatg gagatatgct
61 cctctcactg ccctctgcac cagcaacatg gattgtcagc tctccatcct cctccttctc
121 agctgctctg ttctcgacag cttcggggaa ctgattccgc agccttccaa tgaagtcaat
181 ctactggatt caaaaacaat tcaaggggag ctgggctgga tctcttatcc atcacatggg
241 tgggaagaga tcagtggtgt ggatgaacat tacacaccca tcaggactta ccaggtgtgc
301 aatgtcatgg accacagtca aaacaattgg ctgagaacaa actgggtccc caggaactca
361 gctcagaaga tttatgtgga gctcaagttc actctacgag actgcaatag cattccattg
421 gttttaggaa cttgcaagga gacattcaac ctgtactaca tggagtctga tgatgatcat
481 ggggtgaaat ttcgagagca tcagtttaca aagattgaca ccattgcagc tgatgaaagt
541 ttcactcaaa tggatcttgg ggaccgtatt ctgaagctca acactgagat tagagaagta
601 ggtcctgtca acaagaaggg attttatttg gcatttcaag atgttggtgc ttgtgttgcc
661 ttggtgtctg tgagagtata cttcaaaaag tgcccattta cagtgaagaa tctggctatg
721 tttccagaca cggtacccat ggactcccag tccctggtgg aggttagagg gtcttgtgtc
781 aacaattcta aggaggaaga tcctccaagg atgtactgca gtacagaagg cgaatggctt
841 gtacccattg gcaagtgttc ctgcaatgct ggctatgaag aaagaggttt tatgtgccaa
901 gcttgtcgac caggtttcta caaggcattg gatggtaata tgaagtgtgc taagtgcccg
961 cctcacagtt ctactcagga agatggttca atgaactgca ggtgtgagaa taattacttc
1021 cgggcagaca aagaccctcc atccatggct tgtacccgac ctccatcttc accaagaaat
1081 gttatctcta atataaacga gacctcagtt atcctggact ggagttggcc cctggacaca
1141 ggaggccgga aagatgttac cttcaacatc atatgtaaaa aatgtgggtg gaatataaaa
1201 cagtgtgagc catgcagccc aaatgtccgc ttcctccctc gacagtttgg actcaccaac
1261 accacggtga cagtgacaga ccttctggca catactaact acacctttga gattgatgcc
1321 gttaatgggg tgtcagagct gagctcccca ccaagacagt ttgctgcggt cagcatcaca
1381 actaatcagg ctgctccatc acctgtcctg acgattaaga aagatcggac ctccagaaat
1441 agcatctctt tgtcctggca agaacctgaa catcctaatg ggatcatatt ggactacgag
1501 gtcaaatact atgaaaagca ggaacaagaa acaagttata ccattctgag ggcaagaggc
1561 acaaatgtta ccatcagtag cctcaagcct gacactatat acgtattcca aatccgagcc
1621 cgaacagccg ctggatatgg gacgaacagc cgcaagtttg agtttgaaac tagtccagac
1681 tgtatgtatt atttcaatgc agtctagagg agggggcagg gatcttgcaa aagatgtctg
1741 atcgtttatt ctcactgttt ctaagtttta aacaaatgtg atacatttaa ggtatattgc
1801 ttgggacatt gcaatttgca gagccctgtg tctgtataca gtatttgtgt ttgtgtgggt
1861 gtacattttg tgtttctttt tttcttgtat gcaaatcaaa catattctaa tgcctgaaat
1921 gcttctgttt ttttttttta gccataaatt gcttttgagg aacattattt aatataggta
1981 acacacttcc agtgtctgtc atttcagata ttccaggttc attgcgtgat tcaatgaacc
2041 acaaaaaaga aacttgctga tccatgagaa tcttaatttt gttttaatcc ttaacacatt
2101 caatagcata tcacagagag aataaggatt ttctaaaatg tgttttatca cttcattcac
2161 attcagaagt aatttgaata gcctgttcct ttaaccccaa atttggctaa aattggccta
2221 aaactggcaa acatttttcc agtaactttt ctttttttca aatgaatttt cttcatactt
2281 aaaaaagccc tttgctaaaa tataattttc aaaaaggtaa aattatgtct atggcactaa
2341 tataaaatga gtagaagtta atgattttac ttaactcatt tttttctttc tttctttttt
2401 tttttttttt ttgagacgga gtcttgctct gtcacccagg ctggagtaca gcagagcgat
2461 ctcggctcac tgcaagctcc tgcaagctcc gcctcctggc ttcacgccat tctccccctc
2521 agcctcccga gtagctggga ctacag
//