LOCUS AF213365 4345 bp mRNA linear HUM 01-DEC-2001
DEFINITION Homo sapiens POB1 (POB1) mRNA, complete cds.
ACCESSION AF213365
VERSION AF213365.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4345)
AUTHORS Wu,G. and Couch,F.J.
TITLE Gene POB1 is amplified and overexpressed in human breast cancer
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 4345)
AUTHORS Wu,G. and Couch,F.J.
TITLE Direct Submission
JOURNAL Submitted (08-DEC-1999) Department of Experimental pathology, Mayo
Clinic and Foundation, 200 1st Street SW, Rochester, MN 55905, USA
FEATURES Location/Qualifiers
source 1..4345
/db_xref="H-InvDB:HIT000074095"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="17"
/map="17q23"
gene 1..4345
/gene="POB1"
CDS 265..3159
/gene="POB1"
/codon_start=1
/product="POB1"
/protein_id="AAL36460.1"
/translation="MDEQSVESIAEVFRCFICMEKLRDARLCPHCSKLCCFSCIRRWL
TEQRAQCPHCRAPLQLRELVNCRWAEEVTQQLDTLQLCSLTKHEENEKDKCENHHEKL
SVFCWTCKKCICHQCALWGGMHGGHTFKPLAEIYEQHVTKVNEEVAKLRRRLMELISL
VQEVERNVEAVRNAKDERVREIRNAVEMMIARLDTQLKNKLITLMGQKTSLTQETELL
ESLLQEVEHQLRSCSKSELISKSSEILMMFQQVHRKPMASFVTTPVPPDFTSELVPSY
DSATFVLENFSTLRQRADPVYSPPLQVSGLCWRLKVYPDGNGVVRGYYLSVFLELSAG
LPETSKYEYRVEMVHQSCNDPTKNIIREFASDFEVGECWGYNRFFRLDLLANEGYLNP
QNDTVILRFQVRSPTFFQKSRDQHWYITQLEAAQTSYIQQINNLKERLTIELSRTQKS
RDLSPPDNHLSPQNDDALETRAKKSACSDMLLEGGPTTASVREAKEDEEDEEKIQNED
YHHELSDGDLDLDLVYEDEVNQLDGSSSSASSTATSNTEENDIDEETMSGENDVEYNN
MELEEGELMEDAAAAGPAGSSHGYVGSSSRISRRTHLCSAATSSLLDIDPLILIHLLA
LKDRSSIENLWGLQPRPPASLLQPTASYSRKDKDQRKQQAMWRVPSDLKMLKRLKTQM
AEVRCMKTDVKNTLSEIKSSSAASGDMQTSLFSADQAALAACGTENSGRLQDLGMELL
AKSSVANCYIRNSTNKKSNSPKPARSSVAGSLSLRRAVDPGENSRSKGDCQTLSEGSP
GSSQSGSRHSSPRALIHGSIGDILPKTEDRQCKALDSDAVVVAVFSGLPAVEKRRKMV
TLGANAKGGHLEGLQMTDLENNSETGELQPVLPEGASAAPEEGMSSDSDIECDTENEE
QEEHTSVGGFHDSFMVMTQPPDEDTHSSFPDGEQIGPEDLSFNTDENSGR"
BASE COUNT 1273 a 849 c 1026 g 1197 t
ORIGIN
1 ctaaagccgg gagaaaggag ctgcggccac cgttcgccct acttctgcgc ctcggggcgg
61 gcgcgccggt aaaaatggcg aaatgggggt aggcggcgct ggacctgaag agatggggcg
121 cgcaggtggg gcggttgtca gagccccctg acgtgggcgc cgggctttta tcggcgattt
181 gatctggcga cctcgggccg gcgcctaaga ggtcagactg cggagcctgc gggtcgccag
241 cggccccgcc gagagccgga ggcaatggat gaacagagcg tggagagcat tgctgaggtt
301 ttccgatgtt tcatttgtat ggagaaattg cgggatgcac gcctgtgtcc tcattgctcc
361 aaactgtgtt gtttcagctg tattaggcgc tggctgacag agcagagagc tcaatgtcct
421 cattgccgtg ctccactcca gctacgagaa ctagtaaatt gtcgttgggc agaagaagta
481 acacaacagc ttgatactct tcaactctgc agtctcacca aacatgaaga aaatgaaaag
541 gacaaatgtg aaaatcacca tgaaaaactt agtgtatttt gctggacttg taagaagtgt
601 atctgccatc agtgtgcact ttggggagga atgcatggcg gacatacctt taaacctttg
661 gcagaaattt atgagcaaca cgtcactaaa gtgaatgaag aggtagccaa acttcgtcgg
721 cgtctcatgg aactgatcag cttagttcaa gaagtggaaa ggaatgtaga agctgtaaga
781 aatgcaaaag atgagcgtgt tcgggaaatt aggaatgcag tggagatgat gattgcacgg
841 ttagacacac agctgaagaa taagcttata acactgatgg gtcagaagac atctctaacc
901 caagaaacag agcttttgga atccttactt caggaggtgg agcaccagtt gcggtcttgt
961 agtaagagtg agttgatatc taagagctca gagatcctta tgatgtttca gcaagttcat
1021 cggaagccca tggcatcttt tgttaccact cctgttccac cagactttac cagtgaatta
1081 gtgccatctt acgattcagc tacttttgtt ttagagaatt tcagcacttt gcgtcagaga
1141 gcagatcctg tttacagtcc acctcttcaa gtttcaggac tttgctggag gttaaaagtt
1201 tacccagatg gaaatggagt tgtgcgaggt tactacttat ctgtgtttct ggagctctca
1261 gctggcttgc ctgaaacttc taaatatgaa tatcgtgtag agatggttca ccagtcctgt
1321 aatgatccta caaaaaatat cattcgagaa tttgcatctg actttgaagt tggagaatgc
1381 tggggctata atagattttt ccgtttggac ttactcgcaa atgaaggata cttgaatcca
1441 caaaatgata cagtgatttt aaggtttcag gtacgttcac caactttctt tcaaaaatcc
1501 cgggaccagc attggtacat tactcagttg gaagctgcac agactagtta tatccaacaa
1561 ataaacaacc ttaaagagag acttactatt gagctgtctc gaactcagaa gtcaagagat
1621 ttgtcaccac cagataacca tcttagcccc caaaatgatg atgctctgga gacacgagct
1681 aagaagtctg catgctctga catgcttctc gaaggtggtc ctactacagc ttctgtaaga
1741 gaggccaaag aggatgaaga agatgaggag aagattcaga atgaagatta tcatcacgag
1801 ctttcagatg gagatctgga tctggatctt gtttatgagg atgaagtaaa tcagctcgat
1861 ggcagcagtt cctctgctag ttccacagca acaagtaata cagaagaaaa tgatattgat
1921 gaagaaacta tgtctggaga aaatgatgtg gaatataaca acatggaatt agaagaggga
1981 gaactcatgg aagatgcagc tgctgcagga cccgcaggta gtagccatgg ttatgtgggt
2041 tccagtagta gaatatcaag aagaacacat ttatgctccg ctgctaccag tagtttacta
2101 gacattgatc cattaatttt aatacatttg ttggccctta aggaccggag cagtatagaa
2161 aatttgtggg gcttacagcc tcgcccacct gcttcacttc tgcagcccac agcatcatat
2221 tctcgaaaag ataaagacca aaggaagcaa caggcaatgt ggcgagtgcc ctctgattta
2281 aagatgctaa aaagactcaa aactcaaatg gccgaagttc gatgtatgaa aactgatgta
2341 aagaatacac tttcagaaat aaaaagcagc agtgctgctt ctggagacat gcagacaagc
2401 cttttttctg ctgaccaggc agctctggct gcatgtggaa ctgaaaactc tggcagattg
2461 caggatttgg gaatggaact cctggcaaag tcatcagttg ccaattgtta catacgaaac
2521 tccacaaata agaagagtaa ttcgcccaag ccagctcgat ccagtgtagc aggtagtcta
2581 tcacttcgaa gagcagtgga ccctggagaa aatagtcgtt caaagggaga ctgtcagact
2641 ctgtctgaag gctccccagg aagctctcag tctgggagca ggcacagttc tccccgagcc
2701 ttgatacatg gcagtatcgg tgatattctg ccaaaaactg aagaccggca gtgtaaagct
2761 ttggattcag atgctgttgt ggttgcagtt ttcagtggct tgcctgcggt tgagaaaagg
2821 aggaaaatgg tcaccttggg ggctaatgct aaaggaggtc atctggaagg actgcagatg
2881 actgatttgg aaaataattc tgaaactgga gagttacagc ctgtactacc tgaaggagct
2941 tcagctgccc ctgaagaagg aatgagtagc gacagtgaca ttgaatgtga cactgagaat
3001 gaggagcagg aagagcatac cagtgtgggc gggtttcacg actccttcat ggtcatgaca
3061 cagcccccgg atgaagatac acattccagt tttcctgatg gtgaacaaat aggccctgaa
3121 gatctcagct tcaatacaga tgaaaatagt ggaaggtaat tgccaaatca agagaactga
3181 cttgcaagct accttgaccc tgaattttgc tgtagttggt gctcaaattt gtcatcagtc
3241 agataatcag atttggtctt atttcttcat tatctcgacc tgaaatagta atttggaaac
3301 tgttggaagg tggcacagtt tagtctaaga cagcagtagt acatgggaaa aacagtatgg
3361 gaagagttct ttgtaatgta aggaaataac aatgtagttc tctattaatt tagcaaattt
3421 gtacattcac aaaaggcagt ttgtctacta cagcagaagg ctggttaact gccagaaaat
3481 gtacctccag gccctgcatg ccgtcagtaa cccgcccggc attggtgctc tactgtcttt
3541 ggctagagct tagttgtgtt taaataatca tctttatatt tggggtttta attacagttc
3601 cattagtgcc tgtagattag tgaacagaaa attgctttgg aagagattct gccctgtaga
3661 cactatgtga ataactgaag taacactaga ctgaatctcc tttttggagt atgtatcttc
3721 tctcacttgt tcaagtacag gcacactgtt caaccgcatg gtatctttct gttgtgtgac
3781 ttctacaaat gttattttaa atgaaattaa gttaacatgg attcattacg ttcctggccc
3841 tgtagacacg tgtaagatta tttaaaattc tttcattttt ttctgcctct tactatacga
3901 ctgtagtgca acaaatattt taaagccccc ttttcttctt tattttcatt agttgtacat
3961 tgatttcagt gtcaacacat ttaaagattc attcatgttg cacagtggct tacatgaacg
4021 tgaaactgtg atataaggtt ttctttcata ctcataatta gcccaaaaca gttgccaaac
4081 tttgccattg tgctcctgca tttgtgtttg agctgctata tatttgtgga aattacactg
4141 aaagttgact aagagactat tgaaaaagca tgaataatta aatatacatg tgagagacat
4201 ctcatctgct gtattttact tagtgaatat tgttcactct tccgtgtctg atgtcttgct
4261 gaatgctgtg actcatagtt tacttttgtt caaaatagtt tgcacttttt gttaataaaa
4321 tcaacttgag aaaaaaaaaa aaaaa
//