LOCUS AF209774 1485 bp mRNA linear HUM 23-MAR-2001
DEFINITION Homo sapiens cytochrome P450 2A13 (CYP2A13)mRNA, complete cds.
ACCESSION AF209774
VERSION AF209774.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1485)
AUTHORS Su,T., Bao,Z., Zhang,Q.Y., Smith,T.J., Hong,J.Y. and Ding,X.
TITLE Human cytochrome P450 CYP2A13: predominant expression in the
respiratory tract and its high efficiency metabolic activation of a
tobacco-specific carcinogen,
4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone
JOURNAL Cancer Res. 60 (18), 5074-5079 (2000)
PUBMED 11016631
REFERENCE 2 (bases 1 to 1485)
AUTHORS Su,T., Smith,T.J., Zhang,Q.-Y., Bao,Z., Hong,J.-Y. and Ding,X.
TITLE Direct Submission
JOURNAL Submitted (30-NOV-1999) Wadsworth Center, New York State Dept. of
Health, Empire State Plaza, Box 509, Albany, NY 12201-0509, USA
FEATURES Location/Qualifiers
source 1..1485
/db_xref="H-InvDB:HIT000073966"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="19"
CDS 1..1485
/note="CYP2A13"
/codon_start=1
/product="cytochrome P450 2A13"
/protein_id="AAG35775.1"
/translation="MLASGLLLVTLLACLTVMVLMSVWRQRKSRGKLPPGPTPLPFIG
NYLQLNTEQMYNSLMKISERYGPVFTIHLGPRRVVVLCGHDAVKEALVDQAEEFSGRG
EQATFDWLFKGYGVAFSNGERAKQLRRFSIATLRGFGVGKRGIEERIQEEAGFLIDAL
RGTHGANIDPTFFLSRTVSNVISSIVFGDRFDYEDKEFLSLLRMMLGSFQFTATSTGQ
LYEMFSSVMKHLPGPQQQAFKELQGLEDFIAKKVEHNQRTLDPNSPRDFIDSFLIRMQ
EEEKNPNTEFYLKNLVMTTLNLFFAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRV
IGKNRQPKFEDRAKMPYTEAVIHEIQRFGDMLPMGLAHRVNKDTKFRDFFLPKGTEVF
PMLGSVLRDPRFFSNPRDFNPQHFLDKKGQFKKSDAFVPFSIGKRYCFGEGLARMELF
LFFTTIMQNFRFKSPQSPKDIDVSPKHVGFATIPRNYTMSFLPR"
BASE COUNT 322 a 438 c 415 g 310 t
ORIGIN
1 atgctggcct cagggctgct tctggtgacc ttgctggcct gcctgactgt gatggtcttg
61 atgtcagtct ggcggcagag gaagagcagg gggaagctgc ctccgggacc caccccattg
121 cccttcattg gaaactacct gcagctgaac acagagcaga tgtacaactc cctcatgaag
181 atcagtgagc gctatggccc tgtgttcacc attcacttgg ggccccggcg ggtcgtggtg
241 ctgtgcggac atgatgccgt caaggaggct ctggtggacc aggctgagga gttcagcggg
301 cgaggcgagc aggccacctt cgactggctc ttcaaaggct atggcgtggc gttcagcaac
361 ggggagcgcg ccaagcagct ccggcgcttc tccatcgcca ccctaagggg ttttggcgtg
421 ggcaagcgcg gcatcgagga acgcatccag gaggaggcgg gcttcctcat cgacgccctc
481 cggggcacgc acggcgccaa tatcgatccc accttcttcc tgagccgcac agtctccaat
541 gtcatcagct ccattgtctt tggggaccgc tttgactatg aggacaaaga gttcctgtca
601 ctgttgcgca tgatgctggg aagcttccag ttcacggcaa cctccacggg gcagctctat
661 gagatgttct cttcggtgat gaaacacctg ccaggaccac agcaacaggc ctttaaggag
721 ctgcaagggc tggaggactt catcgccaag aaggtggagc acaaccagcg cacgctggat
781 cccaattccc cacgggactt catcgactcc tttctcatcc gcatgcagga ggaggagaag
841 aaccccaaca cagagttcta cttgaagaac ctggtgatga ccaccctgaa cctcttcttt
901 gcgggcactg agaccgtgag caccaccctg cgctacggtt tcctgctgct catgaagcac
961 ccagaggtgg aggccaaggt ccatgaggag attgacagag tgatcggcaa gaaccggcag
1021 cccaagtttg aggaccgggc caagatgccc tacacagagg cagtgatcca cgagatccaa
1081 agatttggag acatgctccc catgggtttg gcccacaggg tcaacaagga caccaagttt
1141 cgggatttct tcctccctaa gggcactgaa gtgttcccta tgctgggctc cgtgctgaga
1201 gaccccaggt tcttctccaa cccccgggac ttcaatcccc agcacttcct ggataagaag
1261 gggcagttta agaagagtga tgcttttgtg cccttttcca tcggaaagcg gtactgtttt
1321 ggagaaggcc tggccagaat ggagctcttt ctcttcttca ccaccatcat gcagaacttt
1381 cgcttcaagt cccctcagtc gcctaaggat atcgacgtgt cccccaaaca cgtgggcttt
1441 gccacgatcc cacgaaacta caccatgagc ttcctgcccc gctga
//