LOCUS AF205403 2159 bp mRNA linear HUM 10-MAY-2000
DEFINITION Homo sapiens keratocan (KERA) mRNA, complete cds.
ACCESSION AF205403
VERSION AF205403.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2159)
AUTHORS Pellegata,N.S., Dieguez-Lucena,J.L., Joensuu,T., Lau,S.,
Montgomery,K.T., Krahe,R., Kivela,T., Kucherlapati,R., Forsius,H.
and de la Chapelle,A.
TITLE Mutations in KERA, encoding keratocan, cause cornea plana
JOURNAL Nat. Genet. 25 (1), 91-95 (2000)
PUBMED 10802664
REFERENCE 2 (bases 1 to 2159)
AUTHORS Pellegata,N.S. and de la Chapelle,A.
TITLE Direct Submission
JOURNAL Submitted (16-NOV-1999) Human Cancer Genetics, Ohio State
University, 420 W 12th Avenue, Columbus, OH 43210, USA
FEATURES Location/Qualifiers
source 1..2159
/db_xref="H-InvDB:HIT000073858"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="12"
/map="12q"
gene 1..2159
/gene="KERA"
CDS 249..1307
/gene="KERA"
/note="KTN"
/codon_start=1
/product="keratocan"
/protein_id="AAF69126.1"
/translation="MAGTICFIMWVLFITDTVWSRSVRQVYEVHDSDDWTIHDFECPM
ECFCPPSFPTALYCENRGLKEIPAIPSRIWYLYLQNNLIETIPEKPFENATQLRWINL
NKNKITNYGIEKGALSQLKKLLFLFLEDNELEEVPSPLPRSLEQLQLARNKVSRIPQG
TFSNLENLTLLDLQNNKLVDNAFQRDTFKGLKNLMQLNMAKNALRNMPPRLPANTMQL
FLDNNSIEGIPENYFNVIPKVAFLRLNHNKLSDEGLPSRGFDVSSILDLQLSHNQLTK
VPRISAHLQHLHLDHNKIKSVNVSVICPSPSMLPAERDSFSYGPHLRYLRLDGNEIKP
PIPMALMTCFRLLQAVII"
BASE COUNT 714 a 399 c 370 g 676 t
ORIGIN
1 gaagaagatc caagaaggct gaggtaagca gtcttctgaa gccctgtcaa agtggaaaca
61 atagatcaaa ggtgttcatg gtgactggga cgagtaggtt tcactgtttc ttataggaga
121 cttgacagct taaagtaaaa acaaattatt ttcgtcaaag tttttttttt tctcttaact
181 gatttttagc aaacctcaga ctgagacaca ggactcaacg gtgtattcct ggaaggcaag
241 gtgctataat ggcaggcaca atctgtttca tcatgtgggt gttattcata acagacactg
301 tgtggtctag aagtgtaagg caggtctatg aagtacatga ttcagatgat tggactattc
361 atgacttcga gtgtcccatg gaatgtttct gcccacccag ttttcctact gctttatatt
421 gtgaaaatag aggtctcaaa gaaattcctg ctattccttc aagaatttgg tatctttatc
481 ttcaaaacaa cctgatagaa accattcctg agaagccatt cgagaatgcc acccagctaa
541 gatggataaa tctaaataag aacaaaataa ccaactacgg aattgaaaaa ggagccctaa
601 gccagctgaa gaagttgctc ttcttatttc tggaagataa tgagctagag gaggtacctt
661 ctccattgcc aagaagttta gaacaattac aattagctag aaataaggtg tccagaattc
721 ctcaagggac ctttagcaat ctggagaacc tgacccttct tgacctacag aacaacaaat
781 tagtggacaa tgcctttcaa agagacactt ttaaaggact caagaatctc atgcagctaa
841 acatggccaa gaatgccctg aggaatatgc ctccaagatt accagccaat acaatgcagt
901 tgtttttaga caacaattcc attgaaggaa taccagaaaa ttattttaat gtgattccta
961 aagtggcctt tttgagacta aatcacaaca aactgtcaga tgagggtctc ccatcaagag
1021 gatttgatgt atcatcaatt ctagatcttc aactgtcgca caatcaactc acaaaggttc
1081 cccgaatcag tgctcatctg cagcaccttc accttgatca taacaaaatt aaaagtgtga
1141 atgtctctgt aatatgtccc agcccatcca tgctgcctgc agaacgagat tccttcagtt
1201 atggacctca tcttcgctac ctccgtctgg atggaaatga aatcaaacca ccaattccaa
1261 tggctttaat gacctgcttc agacttctgc aggctgtcat tatttaaaca cattctcacc
1321 aaatctaaaa ttagtttaat gagctgtttc tgacatgaat gtggttacca ttaataggtt
1381 taggacacaa gtcatattcc cattgctctc ggccaccatt ttcatttgtg cagtgtattt
1441 ttctattcaa agatgctttt gccagtcaca tgcatcacag cctgcattaa tttgcttctc
1501 tcttaattaa taacacagac acagagttaa gatagtttat caactcaaag atagttttat
1561 tttggtctct tccatagctt attaacacta aagaaaacaa ttacatcctt atacaataaa
1621 agggacacat ttgtgtatgt ttaaaattac ttatgcagat accgtaattt acagtataaa
1681 tgtaataatc aaacaggagg ataacgacct gaagaaaatg agaaaataaa atatttctta
1741 attgtaatca taataaaaca attgcagatt gctaagtagc tgttggtggt acaagtttga
1801 tatttagctt gagaatgggt atggaatgaa tcaaatactt catcactaaa gaattcttgt
1861 tatttaatat caaataatga aacagcagtc acttctagtt cattaccatt tcttgtagct
1921 gttgttttta gatatagtcc actgcattct tataagttct aaattttatg tttattataa
1981 tgcatttctt gtggaatctt agtgttttaa catttgaaat ccacttaaac tgcaaattgt
2041 tctttatatt tgattgtgtt ttttggattt tctaaataaa aatattgaat gctttctaac
2101 aaaacagaat atttcaaaga aattagcaag cttcattaaa gaacatgttt taataaaaa
//