LOCUS AF202063 2418 bp mRNA linear HUM 24-JAN-2000
DEFINITION Homo sapiens fibroblast growth factor receptor 4, soluble-form
splice variant (FGFR4) mRNA, complete cds.
ACCESSION AF202063
VERSION AF202063.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2418)
AUTHORS Takaishi,S., Sawada,M., Morita,Y., Seno,H., Fukuzawa,H. and
Chiba,T.
TITLE Identification of a novel alternative splicing of human FGF
receptor 4: soluble-form splice variant expressed in human
gastrointestinal epithelial cells
JOURNAL Biochem. Biophys. Res. Commun. 267 (2), 658-662 (2000)
PUBMED 10631118
REFERENCE 2 (bases 1 to 2418)
AUTHORS Takaishi,S., Sawada,M., Morita,Y., Seno,H., Fukuzawa,H. and
Chiba,T.
TITLE Direct Submission
JOURNAL Submitted (02-NOV-1999) Division of Gastroenterology and
Hepatology, Department of Internal Medicine, Kyoto University
Hospital, Shogoin-kawara-cho 54, Sakyo-ku, Kyoto 606-8507, Japan
FEATURES Location/Qualifiers
source 1..2418
/db_xref="H-InvDB:HIT000073781"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="5"
/map="5q35"
/cell_line="Caco-2; 407"
/cell_type="epithelium"
/tissue_type="intestine"
gene 1..2418
/gene="FGFR4"
CDS 37..2325
/gene="FGFR4"
/note="receptor tyrosine kinase"
/codon_start=1
/product="fibroblast growth factor receptor 4,
soluble-form splice variant"
/protein_id="AAF27432.1"
/translation="MRLLLALLGVLLSVPGPPVLSLEASEEVELEPCLAPSLEQQEQE
LTVALGQPVRLCCGRAERGGHWYKEGSRLAPAGRVRGWRGRLEIASFLPEDAGRYLCL
ARGSMIVLQNLTLITGDSSTSSNDDEDPKSHRDLSNRHSYPQQAPYWTHPQRMEKKLH
AVPAGNTVKFRCPAAGNPTPTIRWLKDGQAFHGGNRIGGIRLRHQHWSLVMESVVPSD
RGTYTCLVENAVGSIRYNYLLDVLERSPHRPILQAGLPANTTAVVGSDVELLCKVYSD
AQPHIQWLKHIVINGSSFGADGFPYVQVLKTADINSSEVEVLYLRNVSAEDAGEYTCL
AGNSIGLSYQSAWLTVLPGTGRIPHLTCDSLTPAGRTKSPTLQFSLESGSSGKSSSSL
VRGVRLSSSGPALLAGLVSLDLPLDPLWEFPRDRLVLGKPLGEGCFGQVVRAEAFGMD
PARPDQASTVAVKMLKDNASDKDLADLVSEMEVMKLIGRHKNIINLLGVCTQEGPLYV
IVECAAKGNLREFLRARRPPGPDLSPDGPRSSEGPLSFPVLVSCAYQVARGMQYLESR
KCIHRDLAARNVLVTEDNVMKIADFGLARGVHHIDYYKKTSNGRLPVKWMAPEALFDR
VYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELFSLLREGHRMDRPPHCPPELYGLM
RECWHAAPSQRPTFKQLVEALDKVLLAVSEEYLDLRLTFGPYSPSGGDASSTCSSSDS
VFSHDPLPLGSSSFPFGSGVQT"
BASE COUNT 441 a 776 c 742 g 459 t
ORIGIN
1 agtccagctt gggtccctga gagctgtgag aaggagatgc ggctgctgct ggccctgttg
61 ggggtcctgc tgagtgtgcc tgggcctcca gtcttgtccc tggaggcctc tgaggaagtg
121 gagcttgagc cctgcctggc tcccagcctg gagcagcaag agcaggagct gacagtagcc
181 cttgggcagc ctgtgcggct gtgctgtggg cgggctgagc gtggtggcca ctggtacaag
241 gagggcagtc gcctggcacc tgctggccgt gtacggggct ggaggggccg cctagagatt
301 gccagcttcc tacctgagga tgctggccgc tacctctgcc tggcacgagg ctccatgatc
361 gtcctgcaga atctcacctt gattacaggt gactcctcga cctccagcaa cgatgatgag
421 gaccccaagt cccataggga cctctcgaat aggcacagtt acccccagca agcaccctac
481 tggacacacc cccagcgcat ggagaagaaa ctgcatgcag tacctgcggg gaacaccgtc
541 aagttccgct gtccagctgc aggcaacccc acgcccacca tccgctggct taaggatgga
601 caggcctttc atggggggaa ccgcattgga ggcattcggc tgcgccatca gcactggagt
661 ctcgtgatgg agagcgtggt gccctcggac cgcggcacat acacctgcct ggtagagaac
721 gctgtgggca gcatccgtta taactacctg ctagatgtgc tggagcggtc cccgcaccgg
781 cccatcctgc aggccgggct cccggccaac accacagccg tggtgggcag cgacgtggag
841 ctgctgtgca aggtgtacag cgatgcccag ccccacatcc agtggctgaa gcacatcgtc
901 atcaacggca gcagcttcgg agccgacggt ttcccctatg tgcaagtcct aaagactgca
961 gacatcaata gctcagaggt ggaggtcctg tacctgcgga acgtgtcagc cgaggacgca
1021 ggcgagtaca cctgcctcgc aggcaattcc atcggcctct cctaccagtc tgcctggctc
1081 acggtgctgc caggtactgg gcgcatcccc cacctcacat gtgacagcct gactccagca
1141 ggcagaacca agtctcccac tttgcagttc tccctggagt caggctcctc cggcaagtca
1201 agctcatccc tggtacgagg cgtgcgtctc tcctccagcg gccccgcctt gctcgccggc
1261 ctcgtgagtc tagatctacc tctcgaccca ctatgggagt tcccccggga caggctggtg
1321 cttgggaagc ccctaggcga gggctgcttt ggccaggtag tacgtgcaga ggcctttggc
1381 atggaccctg cccggcctga ccaagccagc actgtggccg tcaagatgct caaagacaac
1441 gcctctgaca aggacctggc cgacctggtc tcggagatgg aggtgatgaa gctgatcggc
1501 cgacacaaga acatcatcaa cctgcttggt gtctgcaccc aggaagggcc cctgtacgtg
1561 atcgtggagt gcgccgccaa gggaaacctg cgggagttcc tgcgggcccg gcgcccccca
1621 ggccccgacc tcagccccga cggtcctcgg agcagtgagg ggccgctctc cttcccagtc
1681 ctggtctcct gcgcctacca ggtggcccga ggcatgcagt atctggagtc ccggaagtgt
1741 atccaccggg acctggctgc ccgcaatgtg ctggtgactg aggacaatgt gatgaagatt
1801 gctgactttg ggctggcccg cggcgtccac cacattgact actataagaa aaccagcaac
1861 ggccgcctgc ctgtgaagtg gatggcgccc gaggccttgt ttgaccgggt gtacacacac
1921 cagagtgacg tgtggtcttt tgggatcctg ctatgggaga tcttcaccct cgggggctcc
1981 ccgtatcctg gcatcccggt ggaggagctg ttctcgctgc tgcgggaggg acatcggatg
2041 gaccgacccc cacactgccc cccagagctg tacgggctga tgcgtgagtg ctggcacgca
2101 gcgccctccc agaggcctac cttcaagcag ctggtggagg cgctggacaa ggtcctgctg
2161 gccgtctctg aggagtacct cgacctccgc ctgaccttcg gaccctattc cccctctggt
2221 ggggacgcca gcagcacctg ctcctccagc gattctgtct tcagccacga ccccctgcca
2281 ttgggatcca gctccttccc cttcgggtct ggggtgcaga catgagcaag gctcaaggct
2341 gtgcaggcac ataggctggt ggccttgggc cttggggctc agccacagcc tgacacagtg
2401 ctcgaccttg atagcatg
//