LOCUS AF201422 7789 bp mRNA linear HUM 29-JUN-2000
DEFINITION Homo sapiens splicing coactivator subunit SRm300 (SRM300) mRNA,
complete cds.
ACCESSION AF201422
VERSION AF201422.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 7789)
AUTHORS Blencowe,B.J., Bauren,G., Eldridge,A.G., Issner,R., Nickerson,J.A.,
Rosonina,E. and Sharp,P.A.
TITLE The SRm160/300 splicing coactivator subunits
JOURNAL RNA 6 (1), 111-120 (2000)
PUBMED 10668804
REFERENCE 2 (bases 1 to 7789)
AUTHORS Blencowe,B.J., Issner,R. and Sharp,P.A.
TITLE Direct Submission
JOURNAL Submitted (03-NOV-1999) Banting and Best Department of Medical
Research, University of Toronto, 112 College Street, Toronto,
Ontario M5G 1L6, Canada
FEATURES Location/Qualifiers
source 1..7789
/db_xref="H-InvDB:HIT000073771"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="16"
gene 1..7789
/gene="SRM300"
CDS 230..7120
/gene="SRM300"
/note="Ser/Arg-related nuclear matrix protein"
/codon_start=1
/product="splicing coactivator subunit SRm300"
/protein_id="AAF21439.1"
/translation="MYNGIGLPTPRGSGTNGYVQRNLSLVRGRRGERPDYKGEEELRR
LEAALVKRPNPDILDHERKRRVELRCLELEEMMEEQGYEEQQIQEKVATFRLMLLEKD
VNPGGKEETPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDPQRRAREA
KQPAPEPPKPYSLVRESNNSRSQPQSRRRRKRRKIEDAGQRAALLDGRERKAQRRRST
GQNLSPRNVSIGLPLQRANVNLRTKSESGLEVQHQPPRAAGPTVQLLLTLLPPPILPA
VGLEVLQLKLIQLPWLGEVLPLLQGDAGREMRLSVNQVLPSTQRASSPETATKQPSSP
YEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVN
PPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSH
REISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRS
RSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRS
PATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRR
SRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSR
SRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRR
SRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSR
SGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSIT
SPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSS
PQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGS
SSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCP
GSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQS
KSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYP
TVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKD
TLRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKE
MSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNS
PLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRS
SGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPS
RRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPR
PRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSAS
PQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRA
APRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTA
RRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRR
SPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRT
TRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRS
RTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRS
RSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRS
RSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRR
RSRSRTPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNG
MLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSS
SSSSSSGSSSSDSEGSSFLCNLSGTEEVPSPTPAPKEAVREGRPPEPTPAKRKRRSSS
SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSFPFPCKAWPSGLAQTCKPQE
ATPWRAEVPQPPEANRLPQGLSVPQLLACGASPSLAPALTTGPAEQQQ"
BASE COUNT 1976 a 2371 c 1923 g 1519 t
ORIGIN
1 gcagcgcggc ccaggcgggg tgcgagtggc gcagtcggag cccgttgcgg cccctgagga
61 agcgaggagg cgtcggcgtc ggctgaggcg ggcggaccgg cgaggcgagg cggcggcccc
121 aggcccgggg actcgggagc tcgagcagcg gcggcggcaa gacctctccc cctcggaggc
181 ggcgggcgga ggcggcggga gcggtggtgc cccccccggg cacggggcca tgtacaacgg
241 gatcgggctg ccgacgcccc ggggcagcgg caccaacggc tacgtccagc gcaacctgtc
301 cctggtgcgg ggccgccggg gtgagcggcc tgactacaag ggagaggagg aactgcggcg
361 cctggaggct gccctggtga agcggcctaa tcctgacatc ctggaccacg agcgcaagcg
421 gcgcgtcgag ctgcgatgcc tcgagctgga ggagatgatg gaagagcaag ggtacgagga
481 acagcaaatt caggaaaaag tggcgacctt tcgactcatg ttgctggaga aggatgtgaa
541 ccctgggggc aaggaggaga ccccagggca gaggccagcg gtcacggaga ctcaccagtt
601 ggcagaatta aatgagaaga agaatgaaag actccgtgct gcctttggca tcagtgattc
661 ttacgtagat ggcagctctt ttgatcctca gcgtcgtgcc cgagaagcta aacaaccagc
721 tcctgagcct cccaaacctt acagccttgt tcgggagtct aacaattctc gctcacaacc
781 ccaaagcaga agaagaagaa aaagaagaaa gatagaggac gcaggtcaga gagcagctct
841 cctcgacggg agagaaagaa aagctcaaag aagaagaagc acaggtcaga atctgagtcc
901 aagaaacgta agcataggtc tcccactcca aagagcaaac gtaaatctaa ggacaaaaag
961 cgaaagcggt ctcgaagtac aacaccagcc cccaagagcc gccgggccca ccgttcaact
1021 tctgctgact ctgcttcctc ctccgatact tcccgcagtc ggtctcgaag tgctgcagct
1081 aaaactcata caactgcctt ggctgggcga agtccttccc ctgcttcagg gcgacgcggg
1141 gagggagatg cgcctttcag tgaaccaagt actaccaagc acacaacggg ctagtagccc
1201 ggagactgct acgaaacagc ctagcagccc ttatgaagac aaagataaag acaagaagga
1261 gaaatctgca actcgaccta gcccctctcc ggaaaggagc agcacaggcc cagaaccacc
1321 tgctcccact ccgctccttg ctgagcgaca tggcggctcc ccacaacccc ttgcaaccac
1381 ccccttaagc caggagccag tgaacccccc atctgaggcc tctccaactc gggaccgttc
1441 accacctaag tctcccgaga aacttcccca gtcttcttcc tcagagagca gcccaccatc
1501 ccctcaacct accaaagttt ctcggcatgc cagctcttcc ccagaaagtc ctaaacctgc
1561 tccagctcca gggtcccacc gagagatttc ttcttctccc acatctaaga atcgctcaca
1621 tggccgagca aaacgggata aatcacattc tcataccccc tcccgtagga tggggaggtc
1681 ccgtagccct gccaccgcta agagagggcg atctcggtct cgaaccccta ccaagagagg
1741 tcattctcga tcccgatctc cccagtggcg taggtccagg tctgcacaga ggtggggaag
1801 atctagaagc ccccagcgac gtggccgctc taggtctcct cagcgaccag gctggtctag
1861 gagcagaaat acccagagaa gaggcaggtc taggtcagca aggcgaggga ggtcccactc
1921 tagatcccca gccactaggg gtagatctcg ttctagaaca ccagcccgcc ggggcaggtc
1981 ccgctctaga acacctgcca ggcggagatc acgatccaga actcccacca ggcgtaggtc
2041 tcggtctaga acaccagccc ggaggggcag gtctcggtct agaacacctg ctaggcgcag
2101 atctaggacc cgatcaccag tacgacgcag gtctcgtagt agatcaccag ccaggagaag
2161 tggcaggtca cgctctagaa ccccagctag acgtggccgc tcacgctcca gaaccccagc
2221 cagacgtggc cgctcacgct ctagaacccc agctagacgc agtggtcgct cacgctccag
2281 aacaccagcc aggagaggga ggtctcggtc taggacacca agacgaggaa gatcccgcag
2341 tagaagctta gttagacgtg gaagatctca ctctagaaca cctcaaagaa gaggcagatc
2401 tggctcatct tcagagcgga aaaacaaatc cagaacatct caaagaagaa gcaggtccaa
2461 ttcaagccca gaaatgaaga aatctcgcat ttcttcaagg cggagcaggt ctctctcttc
2521 accacggtcc aaagcaaaat ctcgcttgtc tttgaggcgc agcctttcag ggtcttcccc
2581 atgccctaag caaaagtcac agacaccacc caggcgcagt cgctctggat cctcccaacc
2641 taaagctaaa tctagaacgc cacccagacg cagtcgctcc agttcttctc cgccacctaa
2701 acagaaatct aagacaccat caagacaaag tcattccagt tcatctcctc atcctaaagt
2761 gaaatctgga acaccaccga ggcaagggtc cataacaagt ccccaggcca atgagcaatc
2821 tgtaacgcca cagagacgga gctgttttga atcatcacct gaccctgagt tgaaatctag
2881 gaccccttct agacatagct gctcagggtc ctctcctcct agagtgaaat ctagcacacc
2941 tcccagacag agcccatcta ggtcatcatc tccacaaccc aaagtgaagg caataatatc
3001 accaagacaa agaagccatt ctggctcctc ttctccaagt cctagtaggg tgacgtcgag
3061 aacaactcca cggcgaagca gatcagtatc tccctgctcc aatgtggaat ccagattgtt
3121 gccaagatac agtcattctg ggtcctcctc accagatacc aaagtgaaac ctgaaacacc
3181 gccaagacaa agtcactcag ggtctatttc accatacccc aaagtaaagg cccaaactcc
3241 accggggcca agtctttctg gatcaaagtc accatgtccc caagagaagt ctaaagactc
3301 actagttcaa agttgccctg gatccctctc tctctgtgca ggagtaaaat ctagcacacc
3361 accaggcgag agctattttg gtgtctcatc tctgcaactg aaaggacaat ctcaaacttc
3421 accagaccac agatctgata cttcaagtcc agaagtgaga cagagtcatt cagaatcacc
3481 atctctgcag agcaaatctc aaacatcacc taagggaggt cggtccaggt cttcatctcc
3541 agtcactgag ctggcatcca gatctccaat aagacaagat agaggtgagt tctcagcgag
3601 tcctatgttg aaatctggaa tgtctcctga gcagagcagg ttccagtctg actcttcttc
3661 atatcctaca gtggactcga attctctctt ggggcagagt agattggaga ctgctgaatc
3721 aaaagagaaa atggccttac cccctcagga ggatgctact gcatcacctc ctagacagaa
3781 agacaaattt agtccctttc cagtacagga taggcctgag tcttcactgg tattcaaaga
3841 cacacttaga accccgccaa gggaaagaag tggtgctggg tcatctccag aaacaaaaga
3901 gcaaaatagt gcattgccta cgtcaagcca agatgaagag ttaatggagg tggtagagaa
3961 gtctgaagaa cccgcaggcc aaatcctgtc tcatttgtct tcagaactta aagaaatgtc
4021 cacaagtaac tttgaatcat ctcctgaagt agaagaaagg cctgctgtgt ctttgactct
4081 tgatcagagc cagtcacagg cttctttgga agcagtagaa gtcccttcaa tggcctcatc
4141 ttggggtggg ccacattttt ctccagaaca taaagaactg tctaactccc cactcaggga
4201 gaacagcttt ggatcacctt tagaatttag aaactcaggc ccacttggta cagaaatgaa
4261 tactggattt tcttctgagg ttaaagaaga tttgaatgga ccgtttctta atcagctgga
4321 aacagatcca tctctagaca tgaaagaaca atcgacaaga tcctctggac acagcagttc
4381 tgagttatcc ccagatgcag tggaaaaggc agggatgtct tcaaatcaga gcatctcttc
4441 acctgtgctt gatgctgtac ccagaacacc ctcgagagaa agaagtagtt ctgcatcttc
4501 tcctgaaatg aaagatggtt tacccagaac tccatcaagg agaagcaggt ctgggtcttc
4561 tccaggactt agagatgggt ctgggactcc ctcgaggcac agcctgtctg ggtcctctcc
4621 tggaatgaaa gatataccta gaacgccatc tagagggaga agcgaatgtg attcttcccc
4681 agaaccgaaa gctttgcctc agactcctag gccgaggagt cgttctccat catccccaga
4741 gctcaacaac aagtgtctta ccccccagag agaaagaagc gggtcagaat catcagttga
4801 tcagaaaact gtggctcgga ctcccctggg gcagagaagt cgttcgggat cctctcaaga
4861 acttgatgtg aaacccagtg catcccctca ggaaagaagt gagtcagact cttctccaga
4921 ttctaaagcc aagacacgaa ccccacttcg gcagaggagt cggtctggat catctccaga
4981 ggttgacagc aaatctcgac tatcccctcg gcgcagtagg tctggttcct cccctgaagt
5041 gaaagataag ccaagagcag cacccagggc acagagtggt tctgattcct ctcctgaacc
5101 taaagctcca gcccctcggg cccttcccag acgaagcaga tcaggttcat caagcaaagg
5161 cagaggccct tctcctgaag gaagcagcag taccgagtcc tctcctgaac atccgcccaa
5221 atccagaact gctcgcagag gttccaggtc atcaccagag cccaagacca agtctcgtac
5281 accacctcga cgtcgcagct ctcgatcatc tccggagcta acaaggaagg ccagactgtc
5341 ccgtagaagc cgctctgcct catcctcacc agaaactcgc tctagaactc ccccaaggca
5401 ccggagaagt ccctcagtgt cttccccgga gccagccgaa aaatcgaggt cttcacgccg
5461 acggcgctca gcttcatctc cacgcactaa gacaacctca aggagaggcc gctctccttc
5521 gccaaagcct cgtggactcc agaggtcccg ttcccgctca aggagagaga aaacaagaac
5581 aacccgacgt cgagataggt ctggatcctc tcagtcaacc tctcggcgaa gacagcggag
5641 ccggtcaagg tcgcgggtta ctcggcggcg gaggggaggc tctggttatc actcaaggtc
5701 acctgcccgg caggaaagtt cccggacctc ctctcgacgc cgaagaggcc gctctcggac
5761 acccccaacc agtcggaagc gttctcgctc acgcacatca ccagccccgt ggaaacgctc
5821 tagatctcga gcctctccag ccactcaccg gcgatccagg tccagaaccc ccctgataag
5881 ccgacgtagg tccagatctc gaacttcacc agtcagccgg agacggtcaa ggtccaggac
5941 ttcagtgact cgacgaagat cccggtcaag agcatcccca gtgagcagaa ggcgatccag
6001 atccagaacg ccaccagtaa cccgccgtcg ttcaaggtct agaacgccaa caacacgccg
6061 ccgctcccgt tctagaactc caccagtgac tcgcagaagg tccagatcca ggactccacc
6121 agtaaccagg aggcgatctc gaagcagaac ttcgcctatc actcgcagaa gatcaagatc
6181 cagaacatct ccggtcaccc gaaggagatc tcgatctcgc acatctccag taactcgaag
6241 aaggtcccgc tctcgaacct caccagtgac acgccgccgc tctaggtccc ggacacctcc
6301 agcacaggat cagccgaggt ctcctgtgcc ttctgctttt tcagaccaat cccgttgttt
6361 gattgcccag accacccctg tagcagggtc tcagtccctt tcctctgggg cagtggcaac
6421 gaccacgtcc tctgctggtg atcacaatgg catgctctct gtccctgccc ctggggtgcc
6481 ccactctgat gtgggggagc cacctgcctc tactggggcc cagcagcctt ctgcattagc
6541 cgccctgcag ccagcaaagg agcggcggag ttcctcctcg tcgtcgtcgt cctctagctc
6601 ctcctcttct tcatcatcgt cgtcgtcgtc ctcctcctcc tctggctcca gttctagtga
6661 ctcagagggc tctagcttcc tgtgcaacct gagtggcact gaagaggtcc ccagccccac
6721 cccagcccca aaggaggctg ttcgagaggg acgtcctccg gagccaaccc cagccaaacg
6781 gaagaggcgc tctagcagtt ccagttccag ctcctcctct tcatcttcct cctcctcctc
6841 ctcctcctct tcttcctcct cctcttcctc ttcttcttct tcctcctcat cttcctcctc
6901 ctcgtcgtct tccttcccct tcccctgcaa agcctggccc tcaggccttg cccaaacctg
6961 caagccccaa gaagccaccc cctggcgagc ggaggtcccg cagcccccgg aagccaatag
7021 actccctcag ggactctcgg tccctcagct actcgcctgt ggagcgtcgc cgtccctcgc
7081 cccagccctc accacgggac cagcagagca gcagcagtga gcggggttcc cggagaggcc
7141 agcgtgggga cagccgctcc cccagccaca agcgcaggag ggagacacct agccctcggc
7201 ccatgagaca ccgctcctcc aggtctccat aaattgtctt tgggggattc caccacaccc
7261 aatgctctgg agccacaagg agtgtccctt cttccccagc agagccgtgg gagggtcctt
7321 gtctgctctc ctttgaacct tggcagccct tggatggagg gctccctttc cctccccttt
7381 tttttttctt tgttcctgtg aaatgttaat ctccgtgagt tcttcctggt tcatgttttc
7441 tggggggttt ggggttggaa ggaattcaaa tgggaattgg gggaagggaa gatacagttc
7501 aggatacccc agcctggaat tagggccagg gaagcatggc cccacttgta tccagaagtt
7561 acccaggggt gattgtgatg gtggttggga ctggaggttg tataaggtgt tcttgaaagg
7621 gagttggaat tagttggtcc ctactgtccc ccatgaggtt gtgaacccct ccccccaact
7681 tttcatgttt cttaaaggca ttttggtttt ttaaaatctg tacagcaaga gcaacttttt
7741 ctgtcaaata aaaatgagaa atgcaggaaa aaaaaaaaaa aaaaaaaaa
//