LOCUS AF198254 2381 bp mRNA linear HUM 02-MAR-2000
DEFINITION Homo sapiens mRNA-binding protein CRDBP mRNA, complete cds.
ACCESSION AF198254
VERSION AF198254.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2381)
AUTHORS Ioannidis,P., Trangas,T., Dimitriadis,E., Samiotaki,M.,
Panoutsakopoulos,G., Kyriazoglou,I., Voutzoulias,S.,
Tsiapalis,C.M., Kittas,C., Agnantis,N. and Pandis,N.
TITLE Ectopic expression of a KH-domain containing protein, highly
homologous to both human IMP-1 and mouse CRD-BP, in benign and
malignant mesenchymal tumors
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 2381)
AUTHORS Ioannidis,P., Trangas,T., Dimitriadis,E. and Samiotaki,M.
TITLE Direct Submission
JOURNAL Submitted (25-OCT-1999) G. Papanikolaou Research Center, St Savvas
Hospital, 171 Alexandras Avenue, Athens, Attica 11522, Greece
FEATURES Location/Qualifiers
source 1..2381
/db_xref="H-InvDB:HIT000073695"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="17"
/map="17q21.3-q22"
/cell_line="MCF-7"
CDS 306..2039
/note="KH-domain containing protein; similar to Mus
musculus CRD-BP (c-myc mRNA coding region
determinant-binding protein) and Homo sapiens IMP-1
(insulin growth factor II mRNA-binding protein)"
/codon_start=1
/product="mRNA-binding protein CRDBP"
/protein_id="AAF37203.1"
/translation="MNKLYIGNLNESVTPADLEKVFAEHKISYSGQFLVKSGYAFVDC
PDEHWAMKAIETFSGKVELQGKRLEIEHSVPKKQRSRKIQIRNIPPQLRWEVLDSLLA
QYGTVENCEQVNTESETAVVNVTYSNREQTRQAIMKLNGHQLENHALKVSYIPDEQIA
QGPENGRRGGFGSRGQPRQGSPVAAGAPAKQQQVDIPLRLLVPTQYVGAIIGKEGATI
RNITKQTQSKIDVHRKENAGAAEKAISVHSTPEGCSSACKMILEIMHKEAKDTKTADE
VPLKTLAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIE
NCCRAEQEIMKKVREAYENDVAAMSLQSHLTPGLNLAAVGLFPASSSAVPPPPSSVTG
AAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSK
VRMVIITGPPEAQFKAQGRIYGKLKEENFFGPKEEVKLETHIRVPASAAGRVIGKGGK
TVNELQNLTAAEVVVPRDQTPDENDQVIVKIIGHFYASQMAQRKIRDILAQVKQQHQK
GQSNQAQARRK"
BASE COUNT 596 a 687 c 664 g 434 t
ORIGIN
1 agaaacgtga cacaccagcc ctctcggagg ggtttcggac cgaagggaag aagctgcgcc
61 gtgtcgtccg tctccctgcg cgccgcgggc acttctcctg ggctctcccc gaactctccc
121 gcgacctctg cgcgccctca ggccgccttc cccgccctgg gctcgggaca acttctgggg
181 tggggtgcaa agaaagtttg cggctcctgc cgccggcctc tccgcctctt ggcctaggag
241 gctcgccgcc cgcgcccgct cgttcggcct tgcccgggac cgcgtcctgc cccgagaccg
301 ccaccatgaa caagctttac atcggcaacc tcaacgagag cgtgaccccc gcggacttgg
361 agaaagtgtt tgcggagcac aagatctcct acagcggcca gttcttggtc aaatccggct
421 acgccttcgt ggactgcccg gacgagcact gggcgatgaa ggccatcgaa actttctccg
481 ggaaagtaga attacaagga aaacgcttag agattgaaca ttcggtgccc aaaaaacaaa
541 ggagccggaa aattcaaatc cgaaatattc caccccagct ccgatgggaa gtactggaca
601 gcctgctggc tcagtatggt acagtagaga actgtgagca agtgaacacc gagagtgaga
661 cggcagtggt gaatgtcacc tattccaacc gggagcagac caggcaagcc atcatgaagc
721 tgaatggcca ccagttggag aaccatgccc tgaaggtctc ctacatcccc gatgagcaga
781 tagcacaggg acctgagaat gggcgccgag ggggctttgg ctctcggggt cagccccgcc
841 agggctcacc tgtggcagcg ggggccccag ccaagcagca gcaagtggac atcccccttc
901 ggctcctggt gcccacccag tatgtgggtg ccattattgg caaggagggg gccaccatcc
961 gcaacatcac aaaacagacc cagtccaaga tagacgtgca taggaaggag aacgcaggtg
1021 cagctgaaaa agccatcagt gtgcactcca cccctgaggg ctgctcctcc gcttgtaaga
1081 tgatcttgga gattatgcat aaagaggcta aggacaccaa aacggctgac gaggttcccc
1141 tgaagaccct ggcccataat aactttgtag ggcgtctcat tggcaaggaa ggacggaacc
1201 tgaagaaggt agagcaagat accgagacaa aaatcaccat ctcctcgttg caagacctta
1261 ccctttacaa ccctgagagg accatcactg tgaagggggc catcgagaat tgttgcaggg
1321 ccgagcagga aataatgaag aaagttcggg aggcctatga gaatgatgtg gctgccatga
1381 gcctgcagtc tcacctgacc cctggcctga acctggctgc tgtaggtctt ttcccagctt
1441 catccagcgc agtcccgccg cctcccagca gcgttactgg ggctgctccc tatagctcct
1501 ttatgcaggc tcccgagcag gagatggtgc aggtgtttat ccccgcccag gcagtgggcg
1561 ccatcatcgg caagaagggg cagcacatca aacagctctc ccggtttgcc agcgcctcca
1621 tcaagattgc accacccgaa acacctgact ccaaagttcg tatggttatc atcactggac
1681 cgccagaggc ccaattcaag gctcagggaa gaatctatgg caaactcaag gaggagaact
1741 tctttggtcc caaggaggaa gtgaagctgg agacccacat acgtgtgcca gcatcagcag
1801 ctggccgggt cattggcaaa ggtggaaaaa cggtgaacga gttgcagaat ttgacggcag
1861 ctgaggtggt agtaccaaga gaccagaccc ctgatgagaa cgaccaggtc atcgtgaaaa
1921 tcatcggaca tttctatgcc agtcagatgg ctcaacggaa gatccgagac atcctggccc
1981 aggttaagca gcagcatcag aagggacaga gtaaccaggc ccaggcacga aggaagtgac
2041 cagcccctcc ctgtcccttc gagtccagga caacaacggg cagaaatcga gagtgtgctc
2101 tccccggcag gcctgagaat gagtgggaat ccgggacacc tgggccgggc tgtagatcag
2161 gtttgcccac ttgattgaga aagatgttcc agtgaggaac cctgatctct cagcccccaa
2221 acacctaccc aattggccca acactgtctg cccctcgggg tgtcagaaat tctagcgcaa
2281 ggcactttta aacgtggatt gtttaaagaa gctctccagg ccccaccaag agggtggatc
2341 acacctcagt gggaagaaaa ataaaatttc cttcaggttt t
//