LOCUS AF192784 3025 bp mRNA linear HUM 12-JUN-2000
DEFINITION Homo sapiens makorin 1 (MKRN1) mRNA, complete cds.
ACCESSION AF192784
VERSION AF192784.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3025)
AUTHORS Gray,T.A., Hernandez,L., Carey,A.H., Schaldach,M.A.,
Smithwick,M.J., Rus,K., Marshall Graves,J.A., Stewart,C.L. and
Nicholls,R.D.
TITLE The ancient source of a distinct gene family encoding proteins
featuring RING and C(3)H zinc-finger motifs with abundant
expression in developing brain and nervous system
JOURNAL Genomics 66 (1), 76-86 (2000)
PUBMED 10843807
REFERENCE 2 (bases 1 to 3025)
AUTHORS Gray,T.A. and Nicholls,R.D.
TITLE Direct Submission
JOURNAL Submitted (07-OCT-1999) Genetics, Case Western Reserve University,
10900 Euclid Ave., Cleveland, OH 44106, USA
FEATURES Location/Qualifiers
source 1..3025
/db_xref="H-InvDB:HIT000073294"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene 1..3025
/gene="MKRN1"
CDS 121..1569
/gene="MKRN1"
/note="RING zinc-finger protein"
/codon_start=1
/product="makorin 1"
/protein_id="AAF17487.1"
/translation="MAEAATPGTTATTSGAGAAAATAAAASPTPIPTVTAPSLGAGGG
GGGSDGSGGGWTKQVTCRYFMHGVCKEGDNCRYSHDLSDSPYSVVCKYFQRGYCIYGD
RCRYEHSKPLKQEEATATELTTKSSLAASSSLSSIVGPLVEMNTGEAESRNSNFATVG
AGSEDWVNAIEFVPGQPYCGRTAPSCTEAPLQGSVTKEESEKEQTAVETKKQLCPYAA
VGECRYGENCVYLHGDSCDMCGLQLLHPMDAAQRSQHIKSCIEAHEKDMELSFAVQRS
KDMVCGICMEVVYEKANPSERRFGILSNCNHTYCLKCIRKWRSAKQFESKIIKSCPEC
RITSNFVIPSEYWVEEKEEKQKLILKYKEAMSNKACRYFDEGRGSCPFGGNCFYKHAY
PDAGREEPQRQKVGTSSRYRAQRRNHFWELIEERENSNPFDNDEEEVVTFELGEMLLM
LLAAGGDDELTDSEDEWDLFHDELEDFYDLDL"
regulatory 3014..3019
/regulatory_class="polyA_signal_sequence"
/gene="MKRN1"
BASE COUNT 772 a 663 c 786 g 804 t
ORIGIN
1 gaacgggtgc ctcagtgtcc ttcccctccc ctcgcctggc ctcgcgtcct ctccccgcag
61 ccggaccgga actatgtgat cccggaagtt ccgggccttt gctgtgtggg ataaacagta
121 atggcggagg ctgcaactcc cggaacaaca gccacaacat caggagcagg agcggcagcg
181 gcgacggcgg cagcagcctc ccccaccccg atccccacag tcaccgcccc gtccctgggg
241 gcgggcggag ggggcggcgg cagcgacggc agcggcggcg gctggactaa acaggtcacc
301 tgcaggtatt ttatgcatgg ggtttgtaag gaaggagaca actgtcgcta ctcgcatgac
361 ctctctgaca gtccgtatag tgtagtgtgc aagtattttc agcgagggta ctgtatttat
421 ggagaccgct gcagatatga acatagcaaa ccattgaaac aggaagaagc aactgctaca
481 gagctaacta caaagtcatc ccttgctgct tcctcaagtc tctcatcgat agttggacca
541 cttgttgaaa tgaatacagg cgaagctgag tcaagaaatt caaactttgc aactgtagga
601 gcaggttcag aggactgggt gaatgctatt gagtttgttc ctgggcaacc ctactgtggc
661 cgtactgcgc cttcctgcac tgaagcaccc ctgcagggct cagtgaccaa ggaagaatca
721 gagaaagagc aaaccgccgt ggagacaaag aagcagctgt gcccctatgc tgcagtggga
781 gagtgccgat acggggagaa ctgtgtgtat ctccacggag attcttgtga catgtgtggg
841 ctgcagctcc tgcatccaat ggatgctgcc cagagatcgc agcatatcaa atcgtgcatt
901 gaggcccatg agaaggacat ggagctctca tttgccgtgc agcgcagcaa ggacatggtg
961 tgtgggatct gcatggaggt ggtctatgag aaagccaacc ccagtgagcg ccgcttcggg
1021 atcctctcca actgcaacca cacctactgt ctcaagtgca ttcgcaagtg gaggagtgct
1081 aagcaatttg agagcaagat cataaagtcc tgcccagaat gccggatcac atctaacttt
1141 gtcattccaa gtgagtactg ggtggaggag aaagaagaga agcagaaact cattctgaaa
1201 tacaaggagg caatgagcaa caaggcgtgc aggtattttg atgaaggacg tgggagctgc
1261 ccatttggag ggaactgttt ttacaagcat gcgtaccctg atgccggtag agaggagcca
1321 cagagacaga aagtgggaac atcaagcaga taccgggccc aacgaaggaa ccacttctgg
1381 gaactcattg aggaaagaga gaacagcaac ccctttgaca acgatgaaga agaggttgtc
1441 acctttgagc tgggcgagat gttgcttatg cttttggctg caggtgggga cgacgaacta
1501 acagactctg aagatgagtg ggacttgttt catgatgagc tggaagattt ttatgacttg
1561 gatctatagc aaccttgcgt ggcgtgtgaa ctggtctgct gacctcagac agcagctgtc
1621 ccctgtggtg gtgtggcagt cctgttgttc tctcctaggc aggcctctca actccaggtg
1681 ctgtcctaag aatttttacc cagggcctgt cttctcaacc cctcaccttt ccctgaggag
1741 tgtgttgttt tccctgttga aaaaagttac aaaaataaat cttaaagtta gttttttgta
1801 acacgaattt aactgtcaga cagttagtgt aagtgtgttg cgtcatctgt tttcaaccag
1861 attgcattta tggacttttc acacactcat tttgaggacc ccaggttcaa aagtaaaagc
1921 actggccctg ctttggggtc caagaatagg agtgatgggt gaagggacct aacctggcca
1981 atagccctct gccccacaca tgggatgtgg atccttgacg tttctggtga aatctgcaca
2041 tctgtgtttt tatatctgtt ccctaccctg taatccctac cacgtgcact tgttctgtgg
2101 ttttggtctc ttgtttaatt gcacacaagt aatactactg ggtaaccaga atcaggtgtg
2161 aatgtgttga gattttttac tgttttgcat gataggaaaa ttgaaaaaga atacgtataa
2221 aagatagaga ggcataacat caatgcagag ttggaagttg gctcccaagg gctgacatgg
2281 tgtgagtgtg tgggtgtgtg ataagcttct catccctgca tagatgcagt attcttagcc
2341 ttagtagaaa aacctggttt agtggtttaa gccttgtgtg gcaaatagat cttaaagggc
2401 aaagcagtat attggtagtt gtcaatatag cagtgctagc tctgtctata taaatagaga
2461 aatggggtta gccatagagg ttaaaactac ctggttatcc catataataa cacaaactgg
2521 gtcttggata cacagttgta tttaatgttt tacgatctac cctttccagt acaggcactt
2581 tctgagaaac ctttgtcctc acttgaggca ttttgttgtc gggtttttgt gtttgttttt
2641 gtgggtattt gcctcattcc acccctgagc tttcaggtag acagacgtga ttcaaaactc
2701 tgttctaagg tgtttattgt agtggagtaa tgggtttgca gtgataagtc atacttttcc
2761 accgaaaggg agggcttggg aatccctgag attagctaaa gttaagttgt tggagaattc
2821 cttgattgga aattgtacct ttgtgttttg ttgctctgtt tcctgaaaat aactcgggga
2881 tgctcctggt ttgtccatct actgctttga ttccttggat cccacccatt ctttcacttt
2941 aagaaaaaac aaataattgt tgcagaggtc tctgtatttt gcagctgccc ttttgtaaga
3001 agcacttttc ccaaataaaa caatt
//