LOCUS AF188125 4371 bp mRNA linear HUM 26-JUL-2016
DEFINITION Homo sapiens TGF-beta resistance-associated protein TRAG (TRAG)
mRNA, partial cds.
ACCESSION AF188125
VERSION AF188125.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4371)
AUTHORS Sanders,S. and Thorgeirsson,S.S.
TITLE TRAG: a novel gene associated with TGF-beta resistance
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 4371)
AUTHORS Sanders,S. and Thorgeirsson,S.S.
TITLE Direct Submission
JOURNAL Submitted (20-SEP-1999) LEC, NIH, 37 Convent Drive, Bldg. 37, Rm
3C28, Bethesda, MD 20892-4255, USA
FEATURES Location/Qualifiers
source 1..4371
/db_xref="H-InvDB:HIT000072961"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="18"
/map="18q21.1"
/tissue_type="liver"
gene 1..>4371
/gene="TRAG"
CDS 1..>4371
/gene="TRAG"
/codon_start=1
/product="TGF-beta resistance-associated protein TRAG"
/protein_id="AAL03983.1"
/translation="MAGNSLVLPIVLWGRKAPTHCISAVLLTDDGATIVTGCHDGQIC
LWDLSVELQVNPRALLFGHTASITCLSKACASSDKQYIVSASESGEMCLWDVSDGRCI
EFTKLACTHTGIQFYQFSVGNQREGRLLCHGHYPEILVVDATSLEVLYSLVSKISPDW
ISSMSIIRSHRTQEDTVVALSVTGILKVWIVTSEISDMQDTEPIFEEESKPIYCQNCQ
SISFCAFTQRSLLVVCSKYWRVFDAGDYSLLCSGPSENGQTWTGGDFVSSDKVIIWTE
NGQSYIYKLPASCLPASDSFRSDVGKAVENLIPPVQHILLDRKDKELLICPPVTRFFY
GCREYFHKLLIQGDSSGRLNIWNISDTADKQGSEEGLAMTTSISLQEAFDKLNPCPAG
IIDQLSVIPNSNEPLKVTASVYIPAHGRLVCGREDGSIVIVPATQTAIVQLLQGEHML
RRGWPPHRTLRGHRNKVTCLLYPHQVSARYDQRYLISGGVDFSVIIWDIFSGEMKHIF
CVHGGEITQLLVPPENCSARVQHCICSVASDHSVGLLSLREKKCIMLASRHLFPIQVI
KWRPSDDYLVVGCSDGSVYVWQMDTGALDRCVMGITAVEILNACDEAVPAAVDSLSHP
AVNLKQAMTRRSLAALKNMAHHKLQTLATNLLASEASDKGNLPKYSHNSLMVQAIKTN
LTDPDIHVLFFDVEALIIQLLTEEASRPNTALISPENLQKASGSSDKGGSFLTGKRAA
VLFQQVKETIKENIKEHLLDDEEEDEEIMRQRREESDPEYRSSKSKPLTLLEYNLTMD
TAKLFMSCLHAWGLNEVLDEVCLDRLGMLKPHCTVSFGLLSRGGHMSLMLPGYNQPAC
KLSHGKTEVGRKLPASEGVGKGTYGVSRAVTTQHLLSIISLANTLMSMTNATFIGDHM
KKGPTRPPRPSTPDLSKARGSPPTSSNIVQGQIKQGWSQLAAMHCVMLPDLLGLDKFR
PPLLEMLARRWQDRCLEVREAAQALLLAELRRIEQAGRKEAIDAWAPYLPQYIDHVIS
PGVTSEAAQTITTAPDASGPEAKVQEEEHDLVDDDITTGCLSSVPQMKKISTSYEERR
KQATAIVLLGVIGAEFGAEIEPPKLLTRPRSSSQIPEGFGLTSGGSNYSLARHTCKAL
TFLLLQPPSPKLPPHSTIRRTAIDLIGRGFTVWEPYMDVSAVLMGLLELCADAEKQLA
NITMGLPLSPAADSARSARHALSLIATARPPAFITTIAKEVHRHTALAANTQSQQNMH
TTTLARAKGEILRVIEILIEKMPTDVVDLLVEVMDIIMYCLEGSLVKKKGLQECFPAI
CRFYMVSYYERNHRIAVGARHGSVALYDIRTGKCQTIHGHKGPITAVAFAPDGRYLAT
YSNTDSHISFWQMNTSLLGSIGMLNSAPQLRCIKTYQVPPVQPASPGSHNALKLARLI
WTSNRNVILMAHDGKEHRFMV"
BASE COUNT 1209 a 995 c 1028 g 1139 t
ORIGIN
1 atggcaggaa acagccttgt tctacccatt gttctttggg gtcgaaaagc gcccacacat
61 tgcatctcag ccgtactttt aacagatgat ggggccacga tcgtaacagg atgtcacgac
121 ggacaaatat gtctctggga tctttcagta gaactgcaag ttaatcctcg agcactgttg
181 tttggtcata cagcatcaat cacttgtttg tctaaagctt gtgcttccag tgacaaacag
241 tatattgtga gtgcatctga aagtggagag atgtgcctct gggatgtgag tgatggcaga
301 tgtattgaat ttacaaaatt agcttgcaca catactggca tacagttcta ccagttctct
361 gttgggaatc agcgagaagg aaggctttta tgccacggac attaccctga aatccttgtt
421 gtggatgcta ccagccttga agtattatac tccttagtat caaagatatc accagactgg
481 attagctcca tgagtattat tcgatcccac cgaacacaag aggacacagt ggtagcactc
541 tcggtgactg gcatcctgaa ggtctggatt gttacctcgg aaataagtga catgcaggat
601 actgagccaa tatttgagga ggaatccaaa ccaatttatt gtcagaattg ccaaagcatc
661 tctttttgtg catttacaca aaggtcactt ttggttgtgt gttccaaata ttggagggtg
721 ttcgatgccg gagactattc cttgttgtgt tcaggtccta gtgaaaatgg acagacatgg
781 accggggggg actttgtctc atcagataaa gtcatcattt ggacagaaaa tgggcaaagt
841 tatatttaca aactacctgc cagttgcctt ccagctagtg attcattccg cagtgatgtg
901 gggaaggcag ttgaaaattt aattcctcct gtacaacata tcctcttgga tcgaaaagat
961 aaagagttgc taatttgtcc tcctgttact cggttcttct atggatgcag agaatatttc
1021 cataaactgt taattcaggg tgattcttct ggaaggttga atatttggaa catatcagac
1081 acagctgata aacagggaag tgaagaaggg ctggcaatga caacttctat tagtttgcaa
1141 gaggcatttg ataaactgaa tccttgtcct gctggaatta tagatcagct gagtgtgatt
1201 cccaatagta atgaacctct taaagtaact gcaagtgtgt acataccagc acatggacga
1261 cttgtttgtg gtcgtgaaga tggaagcata gttattgtac ctgccacaca gacggccata
1321 gtacagctgt tgcaagggga acacatgctc agaagaggtt ggccacctca cagaacactc
1381 cgtggtcatc ggaacaaagt cacatgtttg ctatatcctc atcaggtctc agctcggtat
1441 gatcaaagat acctgatatc tggaggtgtg gatttttcag tcataatttg ggacatattt
1501 tctggagaaa tgaaacatat cttctgtgtt catggtggtg agattactca acttctagtt
1561 ccacctgaaa actgtagtgc aagagtacag cactgcatct gctctgtagc cagtgaccac
1621 tcagtaggac ttctaagttt gcgagagaaa aaatgcataa tgttggcatc tcgtcacctt
1681 tttcctattc aagtaatcaa atggaggcct tctgatgatt acctggtggt ggggtgttca
1741 gatggttctg tgtacgtctg gcaaatggat actggtgcat tggatcgttg tgtgatgggg
1801 ataacagcag ttgagattct aaacgcttgt gatgaagctg ttcctgctgc tgttgattca
1861 cttagtcatc cagcagtcaa cctaaaacaa gctatgacga gacgtagtct tgctgctctt
1921 aaaaatatgg cccatcataa gctacaaacc cttgcaacta acctcttggc ttctgaggca
1981 tctgacaagg gaaatttacc taaatattct cataactccc tgatggttca agcaataaag
2041 acaaacctaa cagacccgga catacatgtg ctattctttg atgtggaagc gttgattatt
2101 caactcctga ctgaagaagc ctctaggccg aatactgctc ttatttcccc agagaatttg
2161 caaaaagcat ctggcagttc agacaaaggg ggctcttttt taactggaaa acgagcagca
2221 gttctcttcc aacaagtgaa agaaacgatc aaagagaaca tcaaggaaca cctccttgat
2281 gatgaagagg aggatgagga gataatgagg cagagaaggg aagaaagtga tcctgaatat
2341 cggtccagca aatcaaagcc attgacccta ttagaatata atttaactat ggacactgca
2401 aagctgttta tgtcctgcct tcacgcctgg ggtttgaatg aagtactgga tgaagtttgc
2461 ctggatcgcc ttggaatgct gaaaccccac tgcaccgtat cgtttggcct cttgtcaaga
2521 ggaggccata tgtcactgat gctgccgggt tataatcagc ctgcttgtaa actgtcacat
2581 gggaaaacag aagtaggaag gaagctgcca gcgtctgagg gagtaggaaa gggaacttac
2641 ggagtgtccc gtgccgtcac cacacagcat ctcctgtcta tcatttcttt ggcaaatact
2701 ttaatgagta tgaccaatgc aacttttatt ggtgatcata tgaagaaggg tcctaccagg
2761 ccacctagac caagcacccc agacctttct aaggcaaggg gttcccctcc aacttccagt
2821 aatattgtgc aaggacagat taaacaaggt tggagtcagt tagctgctat gcactgtgtt
2881 atgctgccag acctactggg attggataaa tttaggcctc cccttctgga gatgctggcc
2941 cgaagatggc aagatcgatg cttggaggtg agagaagccg cacaggccct gcttctggcg
3001 gaactgagaa gaattgagca ggcaggcagg aaggaagcca ttgatgcctg ggctccttac
3061 ttacctcagt acatagacca cgtcatatca cctggagtca catcagaagc cgcgcagact
3121 atcaccacgg ctcctgatgc ctcagggcct gaagcaaaag tccaggagga agagcatgac
3181 cttgttgacg atgacatcac cactggttgc ttatcaagtg tcccacaaat gaaaaaaatt
3241 tctacatctt acgaggaaag acggaagcaa gctaccgcta ttgttttact tggagtaata
3301 ggagctgaat ttggtgctga aattgaacct cctaaactat tgaccagacc tcgaagctct
3361 agccaaattc ctgagggatt cgggttgact agtggtggat ccaactactc gctggccaga
3421 catacttgca aggcactgac gtttcttctg ctacagcctc caagccccaa acttcctcca
3481 cacagcacta tccgaagaac agccattgat ctgattggac gtgggttcac tgtttgggag
3541 ccttacatgg atgtgtccgc tgttctgatg gggcttctcg aactttgtgc cgatgccgag
3601 aaacaacttg ccaacatcac aatggggttg cctctgagcc cagcagctga ctcggcccgc
3661 tctgcgaggc atgccctctc gctcattgcc accgccagac cacccgcctt catcaccacc
3721 atagccaaag aggtacacag acatacggct cttgcagcaa atacccaatc acagcagaat
3781 atgcacacaa caactcttgc acgagctaaa ggggaaattt tgagagtcat tgaaattctt
3841 attgaaaaga tgcccacaga tgttgtggat cttctcgtgg aggttatgga catcattatg
3901 tactgccttg aaggatcttt agttaaaaag aaaggtcttc aagaatgttt cccagccatc
3961 tgcaggttct acatggtcag ctattatgag cggaatcaca gaatagcagt tggagctcgc
4021 catggttcag tggccctgta cgacatccgg actggaaaat gtcagacaat ccatggacac
4081 aagggaccaa tcactgcagt ggcttttgct cctgatggaa gatatcttgc cacctactca
4141 aacactgaca gccacatttc tttttggcag atgaacacgt cactgctggg aagcatcggc
4201 atgctgaact cggcacctca gctgcgctgc attaaaacct accaggtgcc ccctgtgcag
4261 cccgcgtccc ccggctccca caatgccctc aagctggccc ggctcatctg gacttccaac
4321 cgcaacgtca tcctcatggc ccatgacggg aaggagcacc gcttcatggt c
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