LOCUS AF187044 2947 bp mRNA linear HUM 26-OCT-1999
DEFINITION Homo sapiens protein tyrosine phosphatase receptor-type O truncated
PTPROt mRNA, alternatively spliced, complete cds.
ACCESSION AF187044
VERSION AF187044.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2947)
AUTHORS Aguiar,R.C., Yakushijin,Y., Kharbanda,S., Tiwari,S., Freeman,G.J.
and Shipp,M.A.
TITLE PTPROt: an alternatively spliced and developmentally regulated
B-lymphoid phosphatase that promotes G0/G1 arrest
JOURNAL Blood 94 (7), 2403-2413 (1999)
PUBMED 10498613
REFERENCE 2 (bases 1 to 2947)
AUTHORS Aguiar,R.C.T. and Shipp,M.A.
TITLE Direct Submission
JOURNAL Submitted (17-SEP-1999) Adult Oncology, Dana Farber Cancer
Institute, 44 Binney St., Boston, MA 02115, USA
FEATURES Location/Qualifiers
source 1..2947
/db_xref="H-InvDB:HIT000072931"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="12"
/map="12p12-p13"
/clone="YAC 931h4"
/note="anti-Ig activated normal B-lymphocytes"
CDS 487..1620
/note="alternatively spliced; truncated; 43 kDa isoform;
mouse PTP-phi homolog; tissue-specific; related to Homo
sapiens GLEPP1 and PTP-U2; similar to the sequence
presented in GenBank Accession Number AF152378"
/codon_start=1
/product="protein tyrosine phosphatase receptor-type O
truncated PTPROt"
/protein_id="AAF04087.1"
/translation="MVTEMNPNVVVISVLAILSTLLIGLLLVTLIILRKKHLQMAREC
GAGTFVNFASLERDGKLPYNWSKNGLKKRKLTNPVQLDDFDAYIKDMAKDSDYKFSLQ
FEELKLIGLDIPHFAADLPLNRCKNRYTNILPYDFSRVRLVSMNEEEGADYINANYIP
GYNSPQEYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEKRRVKCDHYWPFTEEP
IAYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWPDHGVPTANAAESIL
QFVHMVRQQATKSKGPMIIHCSAGVGRTGTFIALDRLLQHIRDHEFVDILGLVSEMRS
YRMSMVQTEEQYIFIHQCVQLMWMKKKQQFCISDVIYENVSKS"
BASE COUNT 825 a 586 c 656 g 880 t
ORIGIN
1 aagtaaaaaa atggaagggg gaaaaggcaa agtattctgc cttccaagtt agatagctat
61 ctttatgaaa ggacatattt caaaggcaat ataaagtctt tatggtgctc ttacctacct
121 atatttgaat tgggggatgc ttcacctgct tattagtgaa agaagaaaga atacacttag
181 taaattaaat tttttttaaa actttgtctt tgctcagaac cagctccacc caaatcactc
241 ttcgcagtga acaaaaccca gacttcagtg actttgctgt gggtggaaga gggagtagct
301 gatttctttg aagttttctg tcaacaagtt ggctccagtc agaaaaccaa acttcaggaa
361 ccagttgctg tttcttccca tgtcgtgacc atctccagcc ttcttcctgc cactgcctac
421 aattgtagtg tcaccagctt tagccatgac agccccagtg tccctacgtt catagccgtc
481 tcaacaatgg ttacagagat gaatcccaat gtggtagtga tctccgtgct ggccatcctt
541 agcacacttt taattggact gttgcttgtt accctcatta ttcttaggaa aaagcatctg
601 cagatggcta gggagtgtgg agctggtaca tttgtcaatt ttgcatcctt agagagggat
661 ggaaagcttc catacaactg gagtaaaaat ggtttaaaga agaggaaact gacaaacccg
721 gttcaactgg atgactttga tgcctatatt aaggatatgg ccaaagactc tgactataaa
781 ttttctcttc agtttgagga gttgaaattg attggactgg atatcccaca ctttgctgca
841 gatcttccac tgaatcgatg taaaaaccgt tacacaaaca tcctaccata tgacttcagc
901 cgtgtgagat tagtctccat gaatgaagag gaaggtgcag actacatcaa tgccaactat
961 attcctggat acaactcacc ccaggagtat attgccaccc aggggccact gcctgaaacc
1021 agaaatgact tctggaagat ggtcctgcaa caaaagtctc agattattgt catgctcact
1081 cagtgtaatg agaaaaggag ggtgaaatgt gaccattact ggccattcac ggaagaacct
1141 atagcctatg gagacatcac tgtggagatg atttcagagg aagagcagga cgactgggcc
1201 tgtagacact tccggatcaa ctatgctgac gagatgcagg atgtgatgca ttttaactac
1261 actgcatggc ctgatcatgg tgtgcccaca gcaaatgctg cagaaagtat cctgcagttt
1321 gtacacatgg tccgacagca agctaccaag agcaaaggtc ccatgatcat tcactgcagt
1381 gctggcgtgg gacggacagg aacattcatt gccctggaca ggctcttgca gcacattcgg
1441 gatcatgagt ttgttgacat cttagggctg gtgtcagaaa tgaggtcata ccggatgtct
1501 atggtacaga cagaggagca gtacattttt atccatcagt gtgtgcaact gatgtggatg
1561 aagaagaagc agcagttctg catcagtgat gtcatatacg agaatgttag caagtcctag
1621 ttcagaatcc ggagcagaga ggacatgatg tgcgcccatc ctcccttgct tccagattgt
1681 tttagtgggc cctgatggtc atttttctaa acagaggccc tgctttgtaa tatgtggcca
1741 aggagataat ttatctcaca gaagcaccgg gaagacttag ccttaaagag cctacagtgt
1801 ccttttggac tctttcactt cgggacattt aataatggac caaattcaac agaacaccag
1861 gaaggtcaag acgctctcca aagggcagga agtacagcac ttccgaagag tttagttggc
1921 cctttgctgg ttgggctgag ttttttattt ttaagtgttt gtttttcagt gcaataattt
1981 ttgtgtgtgt gtgattctta tcagaaagtt gaattgtttt ctgcctacac cgttcatcag
2041 ccccataacc caggaaggaa caggcattgt tagcatcaga ttatacctca ttattaaaag
2101 gaggcatggc cacacatgaa gaaatggtca ttctacttca aagaaattga gccagcacta
2161 tctgtactcc aacattaccg gatctggatt gggggaggtt ggtcagggaa gagaggggtt
2221 ctacccacag atcaactgtg taatctttta ctattcaagc tataattcag cttcaaagta
2281 gagtagaaaa aaaattgtct taactgttct agttcttgat ggttttcttc cttattaaca
2341 gttggtgttt cttccttggc ccttttggac taatgttact gtccaagttc tttctcaaga
2401 aaccacatct ggttcagaag agtgtcaagt tggactcttt gaactctgtt gctgtctgag
2461 caatcgtggt gcctagactt tgcattcctt gttctgttga cctgcataca tgtgagagct
2521 atttctttaa gaactatata ggctgtgaaa acgcactttc tttcccccaa agagctggga
2581 atttatgaag ttatggcaat gaactgcagc atgctgggac aattatttga ctactttttt
2641 ttgtaatatt gtcaaatgtc tctatggatt ctgacagaga tttctttttg ttttgttatt
2701 cttttggttg tcagtttcat tttaacgagt gtaactagta acattttatt ctttggattt
2761 tgtataatta cagtacatga ttgtgtattg tgacatgaat gctgtcaaaa tgacattgat
2821 ggcattgtga agcctgttac tttgtgtcac ttcctgataa ataagaggtg atgacatgga
2881 tatacaacag aaaacacttt gagttgaaag taaacacaag ctggctgctt ccctgtggca
2941 actgtgg
//