LOCUS AF184215 10462 bp DNA linear HUM 14-JUL-2016
DEFINITION Homo sapiens GTX (GTX) gene, complete cds; and inositol
polyphosphate-5-phosphatase (INPP5A) gene, partial cds.
ACCESSION AF184215
VERSION AF184215.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 10462)
AUTHORS Lee,S.H., Davison,J.A., Vidal,S.M. and Belouchi,A.
TITLE Cloning, expression and chromosomal location of NKX6B TO 10Q26, a
region frequently deleted in brain tumors
JOURNAL Mamm. Genome 12 (2), 157-162 (2001)
PUBMED 11210186
REFERENCE 2 (bases 1 to 10462)
AUTHORS Lee,S.H., Davison,J., Vidal,S.M. and Belouchi,A.
TITLE Direct Submission
JOURNAL Submitted (08-SEP-1999) Department of Biochemistry, Microbiology
and Immunology, University of Ottawa, 451 Smyth Rd, Ottawa, ON K1H
8M5, Canada
FEATURES Location/Qualifiers
source 1..10462
/organism="Homo sapiens"
/mol_type="genomic DNA"
/db_xref="taxon:9606"
/chromosome="10"
/map="10q26"
gene <5615..>6647
/gene="GTX"
mRNA join(<5615..6020,6111..6283,6393..>6647)
/gene="GTX"
/product="GTX"
CDS join(5615..6020,6111..6283,6393..6647)
/gene="GTX"
/note="glial and testis-specific homeobox protein"
/codon_start=1
/product="GTX"
/protein_id="AAK13251.1"
/translation="MDTNRPGAFVLSSAPLAALHNMAEMKTSLFPYALQGPAGFKAPA
LGGLGAQLPLGTPHGISDILGRPVGAAGGGLLGGLPRLNGLASSAGVYFGPAAAVARG
YPKPLAELPGRPPIFWPGVVQGAPWRDPRLAGPAPAGGVLDKDGKKKHSRPTFSGQQI
FALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKRHAAEMASAKKKQ
DSDAEKLKVGGSDAEDDDEYNRPLDPNSDDEKITRLLKKHKPSNLALVSPCGGGAGDA
L"
gene complement(<9541..>10462)
/gene="INPP5A"
mRNA complement(<9541..>10462)
/gene="INPP5A"
/product="inositol polyphosphate-5-phosphatase"
CDS complement(9541..>10462)
/gene="INPP5A"
/codon_start=2
/product="inositol polyphosphate-5-phosphatase"
/protein_id="AAK13252.1"
/translation="SFYFLHESLKNIYQFDFKAKKYRKVAGKEIYSDTLESTPMLEKE
KFRRLLPRVQMVKKRLHPDEVVIADCAFDLVNIHLFHDASNLVAWETSPSVYSGIRHK
ALGYVLDRIIDQRFEKVSYFVFGDFNFRLDSKSVVETLSAKPPMQTVRAADTNEVVKL
IFRESDNDRKVMLQLEKKLFDYFNQEVFRDNNGTALLEFDKELSVFKDRLYELDISFP
PSYPYSEDARQGEQYMNTRCPAWCDRILMSPSAKELVLRSESEEKVVTYDHIGPNVCM
GDHKPVFLAFRIMPGAGKPHAHVHKCCVVQ"
BASE COUNT 1910 a 3351 c 3353 g 1833 t
ORIGIN
1 aagcttggcc tgtctgcacc cagcaccccc gggtgtcctc ctgggagggc tggaccttgt
61 ctcttggcag caccgtgggg ccctcagagc cctccatcta gttccgggca gggcagggcc
121 ccttcccaac accatcggct gcctctggtc actcccaccc aggggcacag ggaatctctg
181 aacacccctt ccctggggag caggaagact tgaaacctcc ttggccaggc cagggcggtt
241 tctactgtgc ccaccagacc cccaggctaa gccagcaggg agactggaag gcccagtgtc
301 cagcccctgc cctgcctcag ggtggctgct cgccctctcc cctcccaccc cacctggaca
361 gcctcggtcc tcagggcgct gtanggagtg aggcacctgt gggatggagc ctcagcgtgg
421 gtgggagaga tgctgcaggg cccaggtgcg gagccgcgtg tgaacgggca ggcggcccgc
481 agcgtctccg tcacgagaag gaagtggatg ctcgtgacaa cagaagaact cggttcgggg
541 gaagaacttg gttgttcagg ggaagaactc ggaccattct ctgtgtgtct ctctctgtgc
601 tttcggtaag tgctgctccs ttggctgctg catttacaag tgacttttaa agaacagaag
661 ctggaaggaa acctggggct caggattcag ggagggggcc ctgcaaggtg ggaggggccc
721 ggccagggcc caggctgtgc aaggaacttc aggcccagtg aagctagagg gtccacaaag
781 gctgggcagg ggccaccctg aaggggtgct cagagagttc aggcaagctc tccctcccct
841 gccatccagg tcctcccagc ccctgccctc ttagcccccc ttcagggcct cctcaacccg
901 cgggtgttcc agattccaca gcctggccca tatcttccag ggagagtgtt cgggtgcccg
961 ggcacccact gtggccccac cccagcttca tcaaagcctc cctccctgtc ctgggccaht
1021 cggcctgggg aaaagcggca ccctctcccc agagcctgat cctccamttc atgtggacct
1081 gtaggtgttg gcaagtgggc aagaggccgc catagcctgg gaagaggggg cacctggacg
1141 ccccacctac agctgggtac cccaaaagct gccgggctct acctggacac cctccagctc
1201 aggagatggg gtggggttga gtttggtcta aacagcaaga cctcaggctc agctgggaaa
1261 tgccacggcg ccaggcccca catccagcat gtcctgtggc tcagggttcc tggaggcacc
1321 tccacagtac ctgctcctcc cggtgggaag tcaggtgcgc ggtcctccct ctccaacccg
1381 cacccgggct ctgaaaattg ctctgaggcc tgcagctgtc acacttgcgt tcattcaccc
1441 acccagcagc atgaattcag tcctggaggc gcccagagga cagagcccct gcatccatcc
1501 atgtcctgag caaggtggcg aggaggcgga catcagacac atccactaat gccttcggca
1561 gggggccagt gccaagaggg gcagccgtgc tgagtgggag tgtgggggct gcaccagacc
1621 gggtggccag ggaggcgtcc ctcaagctga gaccgcgtgg aggaggtgag ccctgtgaag
1681 tgggggggca gagtggccgg ggtgggtgag cctgggggcc acgaggggac cagtggaggg
1741 cctggcaggc atgggatggc attaggtgga aacaggtgga ggtggagact cgcgatctct
1801 gaaataaagc cgctgctagc aggctggtgc tcagcaggca gtgctggaag tgtgagaagg
1861 ggccaggcta ggccaggatg aggagtggag cctcctctgc ccacctaggg gcgtcaactc
1921 ccacccctgg gcggtcccca ccccagccct cagcgctcat ggcctttcag acccggctgg
1981 gtccatgagc ccagtgggac gccggggctg cctggctggg atctgcgcct gcctcccagc
2041 cctttcccgc tgccctggca gggctgcccc cagagggcac gggagatggg gttggggtct
2101 gtcctgcgtg ggaggcaggg ccccttcgag ttgtgttgtg gggtggggtt ttctctagcc
2161 ccccttcccc ttccagcaat tccagagcgt cctggtgggc tcctctgttt ccaagcaaca
2221 gaaggcaccc cgcctgggcc cgggctcctg ggggtcctgg taaccccacg ccgctgcttc
2281 cgtgggtggg gcccacagag gggtcccttg agtcatcttg ggcctttttt ggttctttgg
2341 tcatgaggac cccagggagg ccccgtctgt gtctggaatg cctggtgcgg ttaccttgtc
2401 aagcctggag aggccgggaa tgcgctcact tcgggaaaaa agacaatgca gggcctttgc
2461 cgggaactgc taggagaccc ccggcctggg ggcgcggtca gggcgggcag cttggcaact
2521 cgcctagggc tgcgcgggac aagtcacctc agtgataaat cagagtttgt gaactctatg
2581 gcctgggcgg ccgaaggcga acgcaggctc cttccctctg tggagttccc ccgtcgcccc
2641 tcagccccca gcgcggggac accggggcct argccggctc tccttccggg ccgacacccc
2701 cgccgtcctc cccgtcgccc gctcccctgc agacgccgcg ggggtgccgg gggagcgcgt
2761 ttgctgctct gacccgcccg cgcccgggcc ggagcccgct gcgttcacgg tgcacccccc
2821 ggacagcccg ggcgcggtaa gagccccaca aatacaggct gaacgagtaa aacaaacttg
2881 aatggcctct gccaaaaccc gcgctctcgg ttttccarcg cggagcgttc gcgccgatgc
2941 cggcagcctt cctcgcggga catctgctcg cgggccagga ggtggcatcg cggacctctc
3001 caggcagcgg ggccgccggg cggcggagcc caggcaaaga catcgcggtc kgaggcgctc
3061 ggaccttccc gggaggaggg ggagttgcct cggtggtttc cgagagggcg gcaccggggg
3121 acgcaggaga aaaggtgcgg gcgggggccg gagaggggac ggggcccgga gtgggcgccg
3181 ggaagcgtag gaggtgaagc caccggaccc acgcgcagct cggcgaggag gagggcggga
3241 aagcgcgtgg ggcgcaggcc ggggagccgg gtaggacgcg gcacctgcgg agcgcgccaa
3301 gacttccacg gcttacaaga acgtgggaga gggacccccc cttacccggc tcctctgcgc
3361 ccccaactca ccctggcccc tcatcccgcg cccctgagcc ctggagagcc gcgcgctccg
3421 cagccagtga cacgccagcc ccacccgcga ccccacgcgt tccctcggca gcccagggag
3481 gaccgggggg cgcagacaga cccagggttt atcgggccgc agcgcagcgc ctccaggtcc
3541 atgtttcctc agccataaaa cagcgctagc gacgccccct gccccgcccc tccaggctgt
3601 gagaagagcc agagcctgtc ccgagcgcgg cttcctcccg ccgttccgcc cgcgcgcgcc
3661 tcctgggcct cagttcggga gacccgcacc cctcccggcc cgcccagggt ctgcccggcc
3721 gcgcagagtg ggggatccca gggcgacagc agcccccgcc cccaactccc cctgcccgcc
3781 ccccccggcc ccgcagttcc cgcgtctcag ctcagagccc gagccttggg cgcgggcgcc
3841 gtcgccttgg ggtgctggga ggggcccgaa cccgacccgg gagggccctt cctcgtgtct
3901 cctccgaggg agcggggcgc aggacaggcc ggggcgggtc tcggggccgg acgggcgctg
3961 ggggttcccg ggccaggctc cgcgggggcc gatcaccggt ggggcggccg cgcccaatcg
4021 aatcccaatc ccagtcgaat cgagtgcgga gtcgacgggg gaagcgaacc ccccgtgaac
4081 gcggggctgc acctcagtgg agccggaaag ccgccggggc agccccgagc gcgcacacac
4141 ccggcggccg caccactgcc ccggagtttg gccgcaggtg gcttttccaa gccgccatcc
4201 aggagcggcc gacggcgcca agtccccgcc tcgacctgca caaaacgaaa acggacgctg
4261 gaggggggcg agggggcgga cgtgagaccc cggccccgaa ccccgggcgc cgccttcctc
4321 cgcggcacag gcccgagaga ggccacgcag cggcgttccc tgcgcacaga ctcgggctcc
4381 ccacgagccg tgggccacag ccacagccgc cccgtgtccc taaatcaata cgagacgtca
4441 ccacagacgt cggagcgttt gctcgcggcc gccgtgcgcg gggctcggag tcatctcacc
4501 gcccggtctg cgggatggat gagcgagcgg ctcccggtgc cgtgggggcg ggggggacac
4561 cggccccccg cgcgcgtcta aggccgcgtt tctgccgctg cgcccccagc ccgcacccac
4621 gttcgggccc tggacagggc ttccgcgctg aggccgtcct ggtctctgtt ctcccggccg
4681 gggattcgcg agaggcggcc cgtgggcgaa gtcgtgggcc caggtcacat cctgggggac
4741 ccccagcggg agacctggag gccgatgacg gggaagtgcc gagccgcgcg tgtggtcccg
4801 ggacccgcct ccccgccccg ctcccgcctg cctcactcct ccaccgcgcc ggccgcgtgt
4861 cggcgaaacc agaggcagct ccgtgcgagc ctcgcccggc cgtgaggccc gtggattccg
4921 tggactcgag gcccgcgtcc tccgccctcc tgtggccccg acctgcccgg agcgcgttcc
4981 ccgccggcgt ccgctgccgc tcacacccac cccagccacg ggcggcggag cagtcgcgac
5041 tgggacgcgg gccgggactc ttccccgagt ggggcgctcc gagcgcgcgg gcgggtcctc
5101 aaatctgcat tctttccgtt aataaaatac gttctcgtat tttttcctga tttcgcatga
5161 aaacctttgc ctaactacac tcccatccaa gcgggattta tttcgtcccc ggggagataa
5221 atcggggcga atttacagcc cgggaggcac ctgccgcgct aatgggccct tcatggagtg
5281 cgcggccggc gggggcgcgc gggcgggggg ggggcgccgg ccaatggccg gaccgcgggg
5341 tccgcagcca atcagcgcgc gcgccgcgcc ccggcggagc ccccgttatc agcgcgtccg
5401 tcccgcgcgg cgccgctccg accggccccg ggagccgccg ccgccgccgc ccgcccgccc
5461 gccccgcgcc ggagccgccc gcccgccccc cgcgccccgc gccccgcgct gcagccgacg
5521 cccgcccggg ccgcgcgcaa acttcccggg ccggcgggca ggggcggcgg cggcggggcc
5581 cggatgggag cccgggccgg cggcggcggc gcccatggac actaaccgcc cgggcgcgtt
5641 cgtgctgagc agtgccccgc tggccgcgct gcacaacatg gccgagatga agacgtcgct
5701 gttcccctac gcgctgcagg gtccggccgg cttcaaggcg cccgcgctgg ggggcctggg
5761 cgcgcagctc ccgctcggga ccccgcacgg catcagcgac atcctgggcc ggcccgtggg
5821 cgcggcgggc gggggcctcc tgggggggct gccccggctc aacgggctcg cgtcgtccgc
5881 cggcgtttac ttcgggcccg cggccgctgt ggcgcgcggc taccccaagc ccctggccga
5941 gctgccgggg cgcccgccca tcttctggcc cggcgtggtg cagggcgcgc cctggaggga
6001 cccgcgtctg gctggcccgg gtgagtggcc cgcgcggggg gtgcggggcg ggtgggcgcg
6061 gagggggacc ccgccggccg ctgacctccc tcccttcccc tcccttgcag ccccggccgg
6121 cggcgtcctg gacaaggacg ggaagaagaa gcactcgcgc ccgaccttct cgggccagca
6181 gatcttcgcg ctggagaaaa ccttcgagca gaccaagtac ctggcgggcc cggagcgcgc
6241 gcgtctcgcc tactcgctgg gcatgaccga gagccaggtg aaggtgagcg cggcggggct
6301 cgggagagca gagccggggg cccgcgtcct gcgaacggcc ccagcgccag ccccgggccc
6361 cgcggccgcc tgaccgcccc gtccactccc aggtctggtt ccagaaccgc cggaccaagt
6421 ggcgcaagcg gcacgcggcg gagatggcgt cggccaagaa gaagcaggac tcggacgccg
6481 agaagctgaa ggtgggcggc tcggacgcgg aggacgacga cgaatacaac cggcccctgg
6541 accccaactc ggacgacgag aagatcacgc ggctgctcaa gaagcacaaa ccctcgaact
6601 tggcgctggt cagcccgtgc ggcggcggcg cgggggacgc cttgtgagga cccgcggggt
6661 gggggcgaat ctatttttgc agaatccggg ggcggccccg ggtgggcgcg agtcgctttg
6721 tatcatcaat aaattattta acgggtcccc gtcggagccg tcgctccgga gcctgcgccg
6781 cgtgtttctt ccgtctcgaa cccggagcga ggcggcccct ccccggcccc ggcttcgccc
6841 ctgcgcccgc ctcgggtcct ccgggttccc ggtgcggasg ctgcgggccc cgggcaggcg
6901 cgaggaggcg gcgaaggcgc agggaagggg cccggcccgc gggaaggaac cgcagcgaca
6961 gccgccagga gcccgggrcg gmgccgggga cggagcagca ggtacggccc ggcccgcctc
7021 gcctcggggc ggattcggac gcgcttgggg gttcccgaaa gggcgggtga gccgcgtacc
7081 cgcctcgagt ccccgcggga ggtttttctt cttccgtttt cccgctttgg ggccacgtac
7141 tcgttgccac cgggcacccg ttcccgctcg gccgagggct tcgctctgat tatttccaaa
7201 gtccctctgc gcatcagcgg atcccatagg cccgccctgg gctcagccgg tggaaccggg
7261 tctgatccgc tgcacggagg cccttcggtc accatcccgc cagatcttcc cgcggtggaa
7321 agcagtttct tccgaactag gaccgcaaag agaaatccga aataattccg cccgcggagc
7381 ggcggggcct cccgtgggtc acgcggggtc agggagccgg aggccccctg ggcaaggccc
7441 gcaagcgccc agccgggggg ctcgggggac ccgtcttcct gccctgaaat gccgccagct
7501 ccgccggggc tgtgactgcg gctgacaaaa cccctccarc ctcccgcarc ctctgttggc
7561 cggggctgcc matccgctgc awcttaatgg gcgtggctgt tgagttttaa tttttaaaaa
7621 ttaaatgtaa ataatgatat cactgcggtg gtacgatttc tcttggcatt tgcggaagcg
7681 ttaaagggaa atagaaaggg cttaaactcg gcgcgttttg ttttaggctc ttagcagcct
7741 tctttacaag gaagcaactc gaagggcaga agcaacgctt ttctgtgggg agcccctctc
7801 agctcagagc agaggggctt cttaaagttt tgaggaaggc aaagcgttga tataatcccg
7861 ttttaaaatg ttgagggata aatcctttat tacagtagaa agtccaaaag gctgtgtttc
7921 tcctctcaat gaacggctta gtgttttgtg acagcgtgtg atacagtgaa attccaggat
7981 ttctaatgag cttgatctca aataaaggct atacangagg ccgctcccct gagttagcat
8041 ttcaaaggtg gcaggagaag ggaaaggaag aaaaagcaac acggggacta ttttcaccac
8101 ggtcaatttt attgcttagg aaccagaccg gtcacttcca aaggcccctc agaacgacca
8161 acagctgaaa cccgcggggc ggactccgtg ttgaaccgcg gacagcggca accacagcag
8221 cgacacggac ctgtgcttcc accaagaaca gattccgcag cggacagcag tcacttgcag
8281 tggtagtatt tatcccacac aaacacccag ctaatgcctt caccccggtc ccaggaactc
8341 tgtagtgttc taaagtaaaa atcaataaaa acatacattt gtgtttcatc aacagactct
8401 ctaatcacct tctaatgctg tacttactgc tataggagaa aaatatttgc aacaaggtta
8461 tgacatgggt tgtctgtagc ggagcaatga ggaaatgtac agttttgttt ctctttaata
8521 tttttatata cagcccatgt taaaagcagt ttctattgga agcaaactag gctatttcta
8581 tttctcccat gatattattg ttgtaacgta ggatacttgg caccataaaa cagtaacaaa
8641 agacagacaa acggtttaca aaattcttaa aaggtacacc caggctagct ataaacttca
8701 cattcagttc ttaatattac acagaagaac ggcatgggag taacggcccg ctggtgcaga
8761 cgtgctgtgg ggccgatttt acccacgatg gcgaggccat gtgtgttttt tacgaatttg
8821 tgtgttgatg gacacacagc tgagctccta gactccaatg ccgcctgctg atgggactct
8881 cctgtgcgtt catactggaa agtatattta gcataagttt tggtaagatt tataaattat
8941 ttttaaaaag tatatattta tatatattta tatatatata aaaatggaaa gcagctgcag
9001 tgtgattcaa aaaccatgtg acacggcgca gagtcagtgc cgcggaagga gcatcggcag
9061 agacagaccc ccttgccatg ctcagggcca cgctgccggc cggcagaggg agtgcccgtc
9121 tcggcttccc cagcccctgg acacacctcc acctggcaga gggggtccct ggacacagtg
9181 gggggtctct gtgctgaaga agcccctcca ctggcaatca ttaaaaactg aaaactgtga
9241 agtctacggt acagaccctc tttgctgtct attagagttt tgacaacagg actgtgactt
9301 atttaaaaaa aaaaaaaaac caatatttct acttaatgtc acatagacag acgagacagt
9361 gaggtatgtg gggctgctcc ggaatggtcc ggaggctgaa gcgaagtgtg gggctggccg
9421 tctagcaggt ggcgcttggg cgggttctcg atgcagcttt caagagtgcg tattcggtcc
9481 acggctacag ggaggctcac gaagtgtcct ctcgtggcgc tggcatctct tcccaccacg
9541 tcactgcacg acacaacact tgtgcacatg ggcatgaggt ttacctgccc cgggcatgat
9601 tcggaaggcc aggaacacgg gcttgtggtc tcccatgcag acgttgggcc caatgtggtc
9661 ataggtgaca accttctcct cgctctccga ccgcagcacc agctccttgg cagacgggga
9721 catgaggatg cggtcacacc aggctgggca ccgggtgttc atgtactgct caccctggcg
9781 ggcgtcctca ctgtacgggt agctgggagg gaacgagatg tccagttcat acagtctgtc
9841 cttaaagaca gacaactcct tgtcaaactc caagagcgcg gtgccgttgt tgtctcggaa
9901 aacctcctgg ttgaagtagt cgaagagttt cttttctaac tggagcataa ccttccggtc
9961 gttgtccgac tcacgaaata tgagcttcac cacttcattg gtgtcggcgg cccggaccgt
10021 ctgcatcggt ggttttgctg agagcgtctc cacgacagac ttggaatcca gccggaagtt
10081 gaaatcacca aatacaaagt aggaaacctt ctcgaatcgc tgatcaatga ttctgtccag
10141 cacgtagccc agtgccttgt gccggattcc cgagtacacg gaagggcttg tttcccaggc
10201 gaccagattg gaagcatcat ggaaaagatg gatattcacc aagtcaaagg cacagtctgc
10261 aatcaccacc tcgtccggat gaagcctttt cttgaccatt tgcactcggg gaagtagtct
10321 gcgaaacttc tccttctcca gcatgggcgt gctctctaag gtatccgagt agatctcttt
10381 gccagcgacc tttctatact tcttagcttt aaagtcaaac tggtagatgt tttttaagga
10441 ctcatgaaga aaataaaagc tt
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