LOCUS AF182277 1520 bp mRNA linear HUM 29-NOV-1999
DEFINITION Homo sapiens cytochrome P450-2B6 (CYP2B6) mRNA, complete cds.
ACCESSION AF182277
VERSION AF182277.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1520)
AUTHORS Wu,J., Dong,H., Yu,Y. and Zhu,L.
TITLE Cloning and identification of human cytochrome CYP2B7 gene cDNA and
construction of its mammalian cell expression recombinant
JOURNAL Teratog., Carcinog. Mutagen. 7 (1), 1-6 (1995)
REFERENCE 2 (bases 1 to 1520)
AUTHORS Zhuge,J., Qian,Y., Xie,H. and Yu,Y.
TITLE Sequence of a new human cytochrome P450-2B6 cDNA
JOURNAL Unpublished
REFERENCE 3 (bases 1 to 1520)
AUTHORS Zhuge,J., Qian,Y., Xie,H. and Yu,Y.
TITLE Direct Submission
JOURNAL Submitted (01-SEP-1999) Pathophysiology, Zhejiang University School
of Medicine, 353 Yan'an Road, Hangzhou, Zhejiang 310031, China
FEATURES Location/Qualifiers
source 1..1520
/db_xref="H-InvDB:HIT000072854"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="19"
/map="19q13.2"
/tissue_type="liver"
gene 1..1520
/gene="CYP2B6"
CDS 3..1478
/gene="CYP2B6"
/EC_number="1.14.14.1"
/codon_start=1
/product="cytochrome P450-2B6"
/protein_id="AAF13602.1"
/translation="MELSVLLFLALLTGLLLLLVQRHPNTHDRLPPGPRPLPLLGNLL
QMDRRGLLKSFLRFREKYGDVFTVHLGPRPVVMLCGVEAIREALVDKAEAFSGRGKIA
MVDPFFRGYGVIFANGNRWKVLRRFSVTTMRDFGMGKRSVEERTQEEAQCLIEELRKS
KGALMDATFLFHSITANIICSIVFGKRFHYQDQEFLKMLNLFYQTFSLISSVFGQLFE
LFSGFLKYFPGAHRQVYKNPQEINAYIGHSVEKHRETLDPSAPRDLIDTYLLHMEKEK
SNAHSEFSHQNLNLNTLSLFFAGTETTSTTLRYGFLLMLKYPHVAERVYREIEQVIGP
HRPPELHDRAKMPYTEAVIYEIQRFSDLLPMGVPHIVTQHTSFRGYIIPKDTEVFLIL
STALHDPHYFEKPDAFNPDHFLDANGALKKTEAFIPFSLGKRICLGEGIARAELFLFF
TTILQNFSMASPVAPEDIDLTPQECGVGKIPPTYQIRFLPR"
BASE COUNT 360 a 462 c 358 g 340 t
ORIGIN
1 ccatggagct cagcgtcctc ctcttccttg cactcctcac aggactcttg ctactcctgg
61 ttcagcgcca ccctaacacc catgaccgcc tcccaccagg gccccgccct ctgccccttt
121 tgggaaacct tctgcagatg gatagaagag gcctactcaa atcctttctg aggttccgag
181 agaaatatgg ggacgtcttc acggtacacc tgggaccgag gcccgtggtc atgctgtgtg
241 gagtagaggc catacgggag gcccttgtgg acaaggctga ggccttctct ggccggggaa
301 aaatcgccat ggtcgaccca ttcttccggg gatatggtgt gatctttgcc aatggaaacc
361 gctggaaggt gcttcggcga ttctctgtga ccactatgag ggacttcggg atgggaaagc
421 ggagtgtgga ggagcggact caggaggagg ctcagtgtct gatagaggag cttcggaaat
481 ccaagggggc cctcatggac gccaccttcc tcttccattc cattaccgcc aacatcatct
541 gctccatcgt ctttggaaaa cgattccact accaagatca agagttcctg aagatgctga
601 acttgttcta ccagactttt tcactcatca gctctgtatt cggccagctg tttgagctct
661 tctctggctt cttgaaatac tttcctgggg cacacaggca agtttacaaa aacccgcagg
721 aaatcaatgc ttacattggc cacagtgtgg agaagcaccg tgaaaccctg gaccccagcg
781 cccccaggga cctcatcgac acctacctgc tccacatgga aaaagagaaa tccaacgcac
841 acagtgaatt cagccaccag aacctcaacc tcaacacgct ctcgctcttc tttgctggca
901 ctgagaccac cagcaccact ctccgctacg gcttcctgct catgctcaaa taccctcatg
961 ttgcagagag agtctacagg gagattgaac aggtgattgg cccacatcgc cctccagagc
1021 ttcatgaccg agccaaaatg ccatacacag aggcagtcat ctatgagatt cagagatttt
1081 ccgaccttct ccccatgggt gtgccccaca ttgtcaccca acacaccagc ttccgagggt
1141 acatcatccc caaggacaca gaagtatttc tcatcctgag cactgctctc catgacccac
1201 actactttga aaaaccagac gccttcaatc ctgaccactt tctggatgcc aatggggcac
1261 tgaaaaagac tgaagctttt atccccttct ccttagggaa gcggatttgt cttggtgaag
1321 gcatcgcccg tgcggaattg ttcctcttct tcaccaccat cctccagaac ttctccatgg
1381 ccagccccgt ggccccagaa gacatcgatc tgacacccca ggagtgtggt gtgggcaaaa
1441 tacccccaac ataccagatc cgcttcctgc cccgctgaag gggctgaggg aagggggtca
1501 aaggattcca gggtcattca
//