LOCUS AF182274 1594 bp mRNA linear HUM 29-NOV-1999
DEFINITION Homo sapiens cytochrome P450-1A2 (CYP1A2) mRNA, complete cds.
ACCESSION AF182274
VERSION AF182274.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1594)
AUTHORS Zhuge,J., Qian,Y., Xie,H. and Yu,Y.
TITLE Sequence of a new human cytochrome P450-1A2 cDNA
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 1594)
AUTHORS Zhuge,J., Qian,Y., Xie,H. and Yu,Y.
TITLE Direct Submission
JOURNAL Submitted (01-SEP-1999) Pathophysiology, Zhejiang University School
of Medicine, 353 Yan'an Road, Hangzhou, Zhejiang 310031, China
FEATURES Location/Qualifiers
source 1..1594
/db_xref="H-InvDB:HIT000072851"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="15"
/map="15q22-qter"
/tissue_type="liver"
gene 1..1594
/gene="CYP1A2"
CDS 9..1559
/gene="CYP1A2"
/EC_number="1.14.14.1"
/codon_start=1
/product="cytochrome P450-1A2"
/protein_id="AAF13599.1"
/translation="MALSQSVPFSATELLLASAIFCLVFWVLKGLRPRVPKGLKSPPE
PWGWPLLGHVLTLGKNPHLALSRMSQRYGDVLQIRIGSTPVLVLSRLDTIRQALVRQG
DDFKGRPDLYTSTLITDGQSLTFSTDSGPVWAARRRLAQNALNTFSIASDPASSSSCY
LEEHVSKEAMALISRLQELMAGPGHFDPYNQVVVSVANVIGAMCFGQHFPESSDEMLS
LVKNTHEFVETASSGNPLDFFPILRYLPNPALQRFKAFNQRFLWFLQKTVQEHYQDFD
KNSVRDITGALFKHSKKGPRASGNLIPQEKIVNLVNDVFGAGFDTVTTAISWSLMYLV
TKPEIQRKIQKELDTVIGRERRPRLSDRPQLPYLEAFILETFRHSSFLPFTIPHSTTR
DTTLNGFYIPKKCCVFVNQWQVNHDPELWEDPSEFRPERFLTADGTAINKPLSEKMML
FGMGKRRCIGEVLAKWEIFLFLAILLQQLEFSVPPGVKVDLIPIYGLTMKHARCEHVQ
ARLRFSIN"
BASE COUNT 328 a 502 c 439 g 325 t
ORIGIN
1 tggtacagat ggcattgtcc cagtctgttc ccttctcggc cacagagctt ctcctggcct
61 ctgccatctt ctgcctggta ttctgggtgc tcaagggttt gaggcctcgg gtccccaaag
121 gcctgaaaag tccaccagag ccatggggct ggcccttgct cgggcatgtg ctgaccctgg
181 ggaagaaccc gcacctggca ctgtcaagga tgagccagcg ctacggggac gtcctgcaga
241 tccgcattgg ctccacgccc gtgctggtgc tgagccgcct ggacaccatc cggcaggccc
301 tggtgcggca gggcgacgat ttcaagggcc ggcctgacct ctacacctcc accctcatca
361 ctgatggcca gagcttgacc ttcagcacag actctggacc ggtgtgggct gcccgccggc
421 gcctggccca gaatgccctc aacaccttct ccatcgcctc tgacccagct tcctcatcct
481 cctgctacct ggaggagcat gtgagcaagg aggctatggc cctgatcagc aggttgcagg
541 agctgatggc agggcctggg cacttcgacc cttacaatca ggtggtggtg tcagtggcca
601 acgtcattgg tgccatgtgc ttcggacagc acttccctga gagtagcgat gagatgctca
661 gcctcgtgaa gaacactcat gagttcgtgg agactgcctc ctccgggaac cccctggact
721 tcttccccat ccttcgctac ctgcctaacc ctgccctgca gaggttcaag gccttcaacc
781 agaggttcct gtggttcctg cagaaaacag tccaggagca ctatcaggac tttgacaaga
841 acagtgtccg ggacatcacg ggtgccctgt tcaagcacag caagaagggg cctagagcca
901 gcggcaacct catcccacag gagaagattg tcaaccttgt caatgacgtc tttggagcag
961 gatttgacac agtcaccaca gccatctcct ggagcctcat gtaccttgtg accaagcctg
1021 agatacagag gaagatccag aaggagctgg acactgtgat tggcagggag cggcggcccc
1081 ggctctctga cagaccccag ctgccctact tggaggcctt catcctggag accttccgac
1141 actcctcctt cttgcccttc accatccccc acagcacaac aagggacaca acgctgaatg
1201 gcttctacat ccccaagaaa tgctgtgtct tcgtaaacca gtggcaggtc aaccatgacc
1261 cagagctgtg ggaggacccc tctgagttcc ggcctgagcg gttcctcacc gccgatggca
1321 ctgctattaa caagcccttg agtgagaaga tgatgctgtt tggcatgggc aagcgccggt
1381 gtatcgggga agtcctggcc aagtgggaga tcttcctctt cctggccatc ctgctacagc
1441 aactggagtt cagcgtgccg ccgggcgtga aagtcgacct gatccccatc tacgggctga
1501 ccatgaagca cgcccgctgt gaacatgtcc aggcgcggct gcgcttctcc atcaactgaa
1561 gaagacacca ccattctgag gccagggagc gagt
//