LOCUS AF180473 1759 bp mRNA linear HUM 03-FEB-2000
DEFINITION Homo sapiens Not2p (NOT2) mRNA, complete cds.
ACCESSION AF180473
VERSION AF180473.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1759)
AUTHORS Albert,T.K., Lemaire,M., van Berkum,N.L., Gentz,R., Collart,M.A.
and Timmers,H.T.
TITLE Isolation and characterization of human orthologs of yeast CCR4-NOT
complex subunits
JOURNAL Nucleic Acids Res. 28 (3), 809-817 (2000)
PUBMED 10637334
REFERENCE 2 (bases 1 to 1759)
AUTHORS Albert,T.K., van Berkum,N.L. and Timmers,H.T.M.
TITLE Direct Submission
JOURNAL Submitted (25-AUG-1999) Laboratory for Physiological Chemistry and
Center for Biomedical Genetics, Utrecht University,
Universiteitsweg 100, Utrecht 3584 CG, The Netherlands
FEATURES Location/Qualifiers
source 1..1759
/db_xref="H-InvDB:HIT000072791"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene 1..1759
/gene="NOT2"
CDS 116..1738
/gene="NOT2"
/note="general negative regulator of transcription subunit
2"
/codon_start=1
/product="Not2p"
/protein_id="AAF29827.1"
/translation="MVRTDGHTLSEKRNYQVTNSMFGASRKKFVEGVDSDYHDENMYY
SQSSMFPHRSEKDMLASPSTSGQLSQFGASLYGQQSALGLPMRGMSNNTPQLNRSLSQ
GTQLPSHVTPTTGVPTMSLHTPPSPSRGILPMNPRNMMNHSQVGQGIGIPSRTNSMSS
SGLGSPNRSSPSIICMPKQQPSRQPFTVNSMSGFGMNRNQAFGMNNSLSSNIFNGTDG
SENVTGLDLSDFPALADRNRREGSGNPTPLINPLAGRAPYVGMVTKPANEQSQDFSIH
NEDFPALPGSSYKDPTSSNDDSKSNLNTSGKTTSSTDGPKFPGDKSSTTQNNNQQKKG
IQVLPDGRVTNIPQGMVTDQFGMIGLLTFIRAAETDPGMVHLALGSDLTTLGLNLNSP
ENLYPKFASPWASSPCRPQDIDFHVPSEYLTNIHIRDKLAAIKLGRYGEDLLFYLYYM
NGGDVLQLLAAVELFNRDWRYHKEERVWITRAPGMEPTMKTNTYERGTYYFFDCLNWR
KVAKEFHLEYDKLEERPHLPSTFNYNPAQQAF"
BASE COUNT 575 a 390 c 385 g 409 t
ORIGIN
1 ggcacgagaa aattcatgcg agggagacgt ggtgggcggt ccttcctgtg acacgaccct
61 tgagtgacag ttctatttga ttgcctccgg tactgtgagg aaaggacacg actctatggt
121 gaggactgat ggacatacat tatctgagaa aagaaactac caggtgacaa acagcatgtt
181 tggtgcttca agaaagaagt ttgtagaggg ggtcgacagt gactaccatg acgaaaacat
241 gtactacagc cagtcttcta tgtttccaca tcggtcagaa aaagatatgc tggcatcacc
301 atctacatca ggtcagctgt ctcagtttgg ggcaagttta tacgggcaac aaagtgcact
361 aggccttcca atgaggggga tgagcaacaa tacccctcag ttaaatcgca gcttatcaca
421 aggcactcag ttaccgagcc acgtcacgcc aacaacaggg gtaccaacaa tgtcacttca
481 cacgcctcca tctccaagca ggggtatttt gcctatgaat cctaggaata tgatgaacca
541 ctcccaggtt ggtcagggca ttggaattcc tagcaggaca aatagcatga gcagttcagg
601 gttaggtagc cccaacagaa gctcgccaag cataatatgt atgccaaagc agcagccttc
661 tcgacagcct tttactgtga acagtatgtc tggatttgga atgaacagga atcaggcatt
721 tggaatgaat aactccttat caagtaacat ttttaatgga acagacggaa gtgaaaatgt
781 gacaggattg gacctttcag atttcccagc attagcagac cgaaacagga gggaaggaag
841 tggtaaccca actccattaa taaacccctt ggctggaaga gctccttatg ttggaatggt
901 aacaaaacca gcaaatgaac aatcccagga cttctcaata cacaatgaag attttccagc
961 attaccaggc tccagctata aagatccaac atcaagtaat gatgacagta aatctaattt
1021 gaatacatct ggcaagacaa cttcaagtac agatggaccc aaattccctg gagataaaag
1081 ttcaacaaca caaaataata accagcagaa aaaagggatc caggtgttac ctgatggtcg
1141 ggttactaac attcctcaag ggatggtgac ggaccaattt ggaatgattg gcctgttaac
1201 atttatcagg gcagcagaga cagacccagg aatggtacat cttgcattag gaagtgactt
1261 aacaacatta ggcctcaatc tgaactctcc tgaaaatctc taccccaaat ttgcgtcacc
1321 ctgggcatct tcaccttgtc gacctcaaga catagacttc catgttccat ctgagtactt
1381 aacgaacatt cacattaggg ataagctggc tgcaataaaa cttggccgat atggtgaaga
1441 ccttctcttc tatctctatt acatgaatgg aggagacgta ttacaacttt tagctgcagt
1501 ggagcttttt aaccgtgatt ggagatacca caaagaagaa cgagtatgga ttaccagggc
1561 accaggcatg gagccaacaa tgaaaaccaa tacctatgag aggggaacat attacttctt
1621 tgactgtctt aactggagga aagtagctaa ggagttccat ctggaatatg acaaattaga
1681 agaacggcct cacctgccat ccaccttcaa ctacaaccct gctcagcaag ccttctaaaa
1741 aaaaaaaaaa aaaaaaaaa
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