LOCUS AF178432 3023 bp mRNA linear HUM 25-FEB-2000
DEFINITION Homo sapiens SH3 protein (AF3P21) mRNA, complete cds.
ACCESSION AF178432
VERSION AF178432.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3023)
AUTHORS Sano,K., Hayakawa,A., Piao,J.H., Kosaka,Y. and Nakamura,H.
TITLE Novel SH3 protein encoded by the AF3p21 gene is fused to the mixed
lineage leukemia protein in a therapy-related leukemia with t(3;11)
(p21;q23)
JOURNAL Blood 95 (3), 1066-1068 (2000)
PUBMED 10648423
REFERENCE 2 (bases 1 to 3023)
AUTHORS Sano,K., Hayakawa,A. and Piao,J.-H.
TITLE Direct Submission
JOURNAL Submitted (17-AUG-1999) Pediatrics, Kobe Univ. Sch. Med., 7-5-1
Kusunoki-cho, Chuo-ku, Kobe, Hyogo 650-0017, Japan
FEATURES Location/Qualifiers
source 1..3023
/db_xref="H-InvDB:HIT000072738"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="3"
/map="3p21"
/tissue_type="leukemia cells"
gene 1..3023
/gene="AF3P21"
CDS 95..2263
/gene="AF3P21"
/codon_start=1
/product="SH3 protein"
/protein_id="AAF35985.1"
/translation="MYRALYAFRSAEPNALAFAAGETFLVLERSSAHWWLAARARSGE
TGYVPPAYLRRLQGLEQDVLQAIDRAIEAVHNTAMRDGGKYSLEQRGVLQKLIHHRKE
TLSRRGPSASSVAVMTSSTSDHHLDAAAARQPNGVCRAGFERQHSLPSSEHLGADGGL
YQIPLPSSQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSV
SSTSLDTLYTSSSPSEPGSSCSPTPPPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEV
ATGTTSASDDLEALGTLSLGTTEEKAAAEAAVPRTIGAELMELVRRNTGLSHELCRVA
IGIIVGHIQASVPASSPVMEQVLLSLVEGKDLSMALPSGQVCHDQQRLEVIFADLARR
KDDAQQRSWALYEDEGVIRCYLEELLHILTDADPEVCKKMCKRNEFESVLALVAYYQM
EHRASLRLLLLKCFGAMCSLDAAIISTLVSSVLPVELARDMQTDTQDHQKLCYSALIL
AMVFSMGEAVPYAHYEHLGTPFAQFLLNIVEDGLPLDTTEQLPDLCVNLLLALNLHLP
AADQNVIMAALSKHANVKIFSEKLLLLLNRGDDPVRIFKHEPQPPHSVLKFLQDVFGS
PATAAIFYHTDMMALIDITVRHIADLSPGDKLRMEYLSLMHAIVRTTPYLQHRHRLPD
LQAILRRILNEEETSPQCQMDRMIVREMCKEFLVLGEAPS"
BASE COUNT 669 a 969 c 822 g 563 t
ORIGIN
1 ggcgggacaa ccgcggcgcg gctcggcgct ccgggcctgg cgttgtggcg ccgcagccct
61 tgccaccttc cctgcacctg ccctgcccgg cctcatgtac cgcgcgctgt acgcgttccg
121 ctcggcggag cccaacgcgc tggcgttcgc cgcgggcgag accttcctgg tgctagagcg
181 aagcagcgcg cactggtggc tggccgcgcg ggcgcgcagt ggtgagacgg gctacgtgcc
241 gccagcctac ctgcgccgcc tgcagggcct ggagcaggat gtcctccagg ccattgaccg
301 ggccatcgag gctgtacaca acacagccat gcgggatggt ggcaagtaca gcctggaaca
361 gcgtggagtc ctccagaagc tgatccacca ccggaaagag accctgtcac gcagaggccc
421 ttcagcctcc agtgttgcag ttatgacctc atcaaccagt gaccaccact tggatgctgc
481 tgcagccagg cagcccaatg gggtgtgtcg agctgggttc gagcggcagc acagcctacc
541 cagttctgag catcttgggg cagatggagg cctctaccag atcccacttc catcttccca
601 gatcccacca cagcctcgcc gagcagcacc caccacaccg cccccaccag tgaagcgccg
661 agaccgcgag gccctgatgg cctctgggag tggtggccac aacaccatgc cctccggggg
721 taactctgtg tccagcggct cctcagtcag cagcacctcc ctggacacgc tctataccag
781 ctccagccca tctgaaccag gctccagctg ctcacccaca cccccacctg tgccccgccg
841 aggcacccac accaccgtgt cccaagtcca gccccctccc tccaaggcat cagcacctga
901 accccctgca gaagaagaag tggcaactgg tacaacctca gcctctgatg acctggaagc
961 cctgggtaca ctgagcctgg ggaccacaga ggagaaggca gcagctgagg cggctgtgcc
1021 caggaccatt ggggccgagc tgatggagct ggtgcggaga aacactggcc tgagccacga
1081 attatgccgg gtggccatcg gcatcatagt gggtcacatc caggcctcgg tgccggccag
1141 ctcaccagtc atggagcagg tcctcctctc actcgtagag ggcaaggacc tcagcatggc
1201 cctgccctca gggcaggtct gccacgacca gcagaggctg gaggtgatct ttgcagacct
1261 ggctcgccgg aaggacgacg cccagcagcg cagttgggca ctatatgagg atgagggtgt
1321 catccgctgc tacctagagg agctgctgca tattctgact gatgcagacc ctgaagtttg
1381 caagaaaatg tgcaagagaa acgagttcga gtctgtcctg gccttggtgg cctattacca
1441 aatggaacac cgagcatcac tgcggctgct gctcctcaag tgctttggcg ccatgtgcag
1501 cctggatgca gccatcatct ccacgcttgt gtcatccgtg ctgcctgtag agctggcgag
1561 ggacatgcag acagacacgc aggaccacca gaaactctgt tactctgccc tcatcctggc
1621 catggtcttc tccatgggag aggcagtgcc ctatgcacac tatgagcacc tgggcacgcc
1681 tttcgcccag ttcctactga acatcgtcga ggatgggctg cccttggaca ccacagagca
1741 gctgccggac ctctgcgtga acctgcttct ggctctcaac ctgcacctgc cagctgctga
1801 ccagaatgtc atcatggctg ccctgagcaa acacgccaat gtcaagatct tctccgagaa
1861 gctgttgttg ctcctgaaca gaggggatga ccctgtgcgc atcttcaaac atgagccaca
1921 gccaccacac tctgtcctca agttcctgca ggacgtgttt ggcagcccgg ccacagctgc
1981 catcttctac cacacagaca tgatggctct cattgacatc actgtgcggc acatcgcaga
2041 cctgtcacca ggagacaagc tgcgcatgga gtacctctcc ctgatgcatg ctatagtccg
2101 caccacaccc tacctgcagc accgccaccg gctacccgac ctgcaggcca tactgcgacg
2161 catcctgaat gaggaggaga cctcacccca gtgccagatg gaccgcatga ttgtccgaga
2221 gatgtgcaag gaattcctgg tgctggggga ggctcccagc tagcaccttg ctgtcctccc
2281 ttccctgcag ctccagtcag tgtgcagggg actcaggggc ttggccctaa gaatgttttg
2341 cactgacagt gggaggggat aaggtggcag aaggaacctg agcaggaccc ccacctgaag
2401 tagaacttaa gagaggggcc aagtgtagga ttggggacca tggtctggga gctgttctgg
2461 ggcaggggga atatgcaagc taaagcccct ctataccctg gtaggcttcc tcttcagcat
2521 gcccccctct tcaccccaca cccatgtgta cactcagagt cctgctgccg ctccaggctg
2581 gaccagaccc ccatccccac ccctcctggt ctgtatcctg ggcctcagca agccatgccc
2641 ctggggtgag gggaggcatc tcccaccagc tctattcttt gccttagctt tgcagtgagt
2701 gctgctcatg tcctcccctc cacccgcaca tgggggtcgc tgcccttcac tcctaccccc
2761 agaggccttg gccaagctgc tgctttgaaa gcgggatctt ggagacaggc catccatcct
2821 ggagcctcat ggaacaggat gatggcactg agaaagccaa tgaccgaatc tcttttctct
2881 gtaaaaatgt agactgaaaa gccatgtgta ttttcctatg tgctgtagct ctcctttgga
2941 aataaatcac aggcatctgg aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
3001 aaaaaaaaaa aaaaaaaaaa aaa
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