LOCUS AF177775 1944 bp mRNA linear HUM 05-SEP-1999
DEFINITION Homo sapiens egasyn mRNA, complete cds.
ACCESSION AF177775
VERSION AF177775.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1944)
AUTHORS Islam,M.R., Waheed,A., Shah,G.N., Tomatsu,S. and Sly,W.S.
TITLE Human Egasyn Binds beta-Glucuronidase But Neither the Esterase
Active Site of Egasyn Nor the C Terminus of beta-Glucuronidase Is
Involved in Their Interaction
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 1944)
AUTHORS Islam,M.R., Waheed,A., Shah,G.N., Tomatsu,S. and Sly,W.S.
TITLE Direct Submission
JOURNAL Submitted (16-AUG-1999) Biochem. and Molecular Biology, St. Louis
University, 1402 S. Grand Blvd, St. Louis, MO 63104, USA
FEATURES Location/Qualifiers
source 1..1944
/db_xref="H-InvDB:HIT000072728"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="16"
/tissue_type="liver"
CDS 28..1731
/note="ER-resident carboxylesterase"
/codon_start=1
/product="egasyn"
/protein_id="AAD53175.1"
/translation="MLLRAFILATLSASAAWGHPSSPPVVDTVHGKVLGKFVSLEGFA
QPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFT
NRKENIPLKLSEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAH
ENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIF
GESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKT
TTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEE
LQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQLDQKTAMSLLWKSYPLVCIA
KELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQ
YRPSFSSDMKPKTVIGDHGDELFSVFGAPFLKEGASEEEIRLSKMVMKFWANFARNGN
PNGEGLPHWPEYNQKEGYLQIGANTQAAQKLKDKEVAFWTNLFAKKAVEKPPQTEHIE
L"
BASE COUNT 486 a 477 c 542 g 439 t
ORIGIN
1 aggccccgag aactgtcgcc cttcacgatg ttgctccgtg cctttatcct ggccactctc
61 tctgcttccg cggcttgggg gcatccgtcc tcgccacctg tggtggacac cgtgcatggc
121 aaagtgctgg ggaagttcgt cagcttagaa ggatttgcac agcctgtggc cattttcctg
181 ggaatccctt ttgccaagcc gcctcttgga cccctgaggt ttactccacc gcagcctgca
241 gaaccatgga gctttgtgaa gaatgccacc tcgtaccctc ctatgtgcac ccaagatccc
301 aaggcggggc agttactctc agagctattt acaaaccgaa aggagaacat tcctctcaag
361 ctttctgaag actgtcttta cctcaatatt tacactcctg ctgacttgac caagaaaaac
421 aggctgccgg tgatggtgtg gatccacgga ggggggctga tggtgggtgc ggcatcaacc
481 tatgatgggc tggcccttgc tgcccatgaa aacgtggtgg tggtgaccat tcaatatcgc
541 ctgggcatct ggggattctt cagcacaggg gatgaacaca gccgggggaa ctggggtcac
601 ctggaccagg tggctgccct gcgctgggtc caggacaaca ttgccagctt tggagggaac
661 ccaggctctg tgaccatctt tggagagtca gcgggaggag aaagtgtctc tgttcttgtt
721 ttgtctccat tggccaagaa cctcttccac cgggccattt ctgagagtgg cgtggccctc
781 acttctgttc tggtgaagaa aggtgatgtc aagcccttgg ctgagcaaat tgctatcact
841 gctgggtgca aaaccaccac ctctgctgtc atggttcact gcctgcgaca gaagacggaa
901 gaggagctct tggagacgac attgaaaatg aaattcttat ctctggactt acagggagac
961 cccagagaga gtcaacccct tctgggcact gtgattgatg ggatgctgct gctgaaaaca
1021 cctgaagagc ttcaagctga aaggaatttc cacactgtcc cctacatggt cggaattaac
1081 aagcaggagt ttggctggtt gattccaatg cagttgatga gctatccact ctccgaaggg
1141 caactggacc agaagacagc catgtcactc ctgtggaagt cctatcccct tgtttgcatt
1201 gctaaggaac tgattccaga agccactgag aaatacttag gaggaacaga cgacactgtc
1261 aaaaagaaag acctgttcct ggacttgata gcagatgtga tgtttggtgt cccatctgtg
1321 attgtggccc ggaaccacag agatgctgga gcacccacct acatgtatga gtttcagtac
1381 cgtccaagct tctcatcaga catgaaaccc aagacggtga taggagacca cggggatgag
1441 ctcttctccg tctttggggc cccattttta aaagagggtg cctcagaaga ggagatcaga
1501 cttagcaaga tggtgatgaa attctgggcc aactttgctc gcaatggaaa ccccaatggg
1561 gaagggctgc cccactggcc agagtacaac cagaaggaag ggtatctgca gattggtgcc
1621 aacacccagg cggcccagaa gctgaaggac aaagaagtag ctttctggac caacctcttt
1681 gccaagaagg cagtggagaa gccaccccag acagaacaca tagagctgtg aatgaagatc
1741 cagccggcct tgggagcctg gaggagcaaa gactggggtc ttttgcgaaa gggattgcag
1801 gttcagaagg catcttacca tggctgggga attgtctggt ggtggggggc aggggacaga
1861 ggccatgaag gagcaagttt tgtatttgtg acctcagctt tgggaataaa ggatcttttg
1921 aaggccaaaa aaaaaaaaaa aaaa
//