LOCUS AF177396 2479 bp mRNA linear HUM 16-OCT-1999
DEFINITION Homo sapiens dickkopf-3 (DKK-3) mRNA, complete cds.
ACCESSION AF177396
VERSION AF177396.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2479)
AUTHORS Krupnik,V.E., Sharp,J.D., Jiang,C., Robison,K., Chickering,T.W.,
Amaravadi,L., Brown,D.E., Guyot,D., Mays,G., Leiby,K., Chang,B.,
Duong,T., Goodearl,A.D., Gearing,D.P., Sokol,S.Y. and McCarthy,S.A.
TITLE Functional and structural diversity of the human Dickkopf gene
family
JOURNAL Gene 238 (2), 301-313 (1999)
PUBMED 10570958
REFERENCE 2 (bases 1 to 2479)
AUTHORS Krupnik,V.E., Sharp,J.D., Jiang,C., Robison,K., Chickering,T.W.,
Amaravadi,L., Brown,D.E., Guyot,D., Mays,G., Leiby,K., Chang,B.,
Duong,T., Goodearl,A.D.J., Gearing,D.P., Sokol,S.Y. and
McCarthy,S.A.
TITLE Direct Submission
JOURNAL Submitted (13-AUG-1999) Cell Biology, Millennium BioTherapeutics
Inc., 640 Memorial Drive, Cambridge, MA 02139, USA
FEATURES Location/Qualifiers
source 1..2479
/db_xref="H-InvDB:HIT000072720"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene 1..2479
/gene="DKK-3"
CDS 38..1090
/gene="DKK-3"
/note="secreted protein"
/codon_start=1
/product="dickkopf-3"
/protein_id="AAF02676.1"
/translation="MQRLGATLLCLLLAAAVPTAPAPAPTATSAPVKPGPALSYPQEE
ATLNEMFREVEELMEDTQHKLRSAVEEMEAEEAAAKASSEVNLANLPPSYHNETNTDT
KVGNNTIHVHREIHKITNNQTGQMVFSETVITSVGDEEGRRSHECIIDEDCGPSMYCQ
FASFQYTCQPCRGQRMLCTRDSECCGDQLCVWGHCTKMATRGSNGTICDNQRDCQPGL
CCAFQRGLLFPVCTPLPVEGELCHDPASRLLDLITWELEPDGALDRCPCASGLLCQPH
SHSLVYVCKPTFVGSRDQDGEILLPREVPDEYEVGSFMEEVRQELEDLERSLTEEMAL
GEPAAAAAALLGGEEI"
BASE COUNT 625 a 618 c 668 g 567 t
ORIGIN
1 ggcacgaggg ggcggcggct gcgggcgcag agcggagatg cagcggcttg gggccaccct
61 gctgtgcctg ctgctggcgg cggcggtccc cacggccccc gcgcccgctc cgacggcgac
121 ctcggctcca gtcaagcccg gcccggctct cagctacccg caggaggagg ccaccctcaa
181 tgagatgttc cgcgaggttg aggaactgat ggaggacacg cagcacaaat tgcgcagcgc
241 ggtggaagag atggaggcag aagaagctgc tgctaaagca tcatcagaag tgaacctggc
301 aaacttacct cccagctatc acaatgagac caacacagac acgaaggttg gaaataatac
361 catccatgtg caccgagaaa ttcacaagat aaccaacaac cagactggac aaatggtctt
421 ttcagagaca gttatcacat ctgtgggaga cgaagaaggc agaaggagcc acgagtgcat
481 catcgacgag gactgtgggc ccagcatgta ctgccagttt gccagcttcc agtacacctg
541 ccagccatgc cggggccaga ggatgctctg cacccgggac agtgagtgct gtggagacca
601 gctgtgtgtc tggggtcact gcaccaaaat ggccaccagg ggcagcaatg ggaccatctg
661 tgacaaccag agggactgcc agccggggct gtgctgtgcc ttccagagag gcctgctgtt
721 ccctgtgtgc acacccctgc ccgtggaggg cgagctttgc catgaccccg ccagccggct
781 tctggacctc atcacctggg agctagagcc tgatggagcc ttggaccgat gcccttgtgc
841 cagtggcctc ctctgccagc cccacagcca cagcctggtg tatgtgtgca agccgacctt
901 cgtggggagc cgtgaccaag atggggagat cctgctgccc agagaggtcc ccgatgagta
961 tgaagttggc agcttcatgg aggaggtgcg ccaggagctg gaggacctgg agaggagcct
1021 gactgaagag atggcgctgg gggagcctgc ggctgccgcc gctgcactgc tgggagggga
1081 agagatttag atctggacca ggctgtgggt agatgtgcaa tagaaatagc taatttattt
1141 ccccangtgt gtgctttaag cgtgggctga ccaggcttct tcctacatct tcttcccagt
1201 aagtttcccc tctggcttga cagcatgagg tgttgtgcat ttgttcagct cccccaggct
1261 gttctccagg cttcacagtc tggtgcttgg gagagtcagg cagggttaaa ctgcaggagc
1321 agtttgccac ccctgtccag attattggct gctttgcctc taccagttgg cagacagccg
1381 tttgttctac atggctttga taattgtttg aggggaggag atggaaacaa tgtggagtct
1441 ccctctgatt ggttttgggg aaatgtggag aagagtgccc tgctttgcaa acatcaacct
1501 ggcaaaaatg caacaaatga attttccacg cagttctttc catgggcata ggtaagctgt
1561 gccttcagct gttgcagatg aaatgttctg ttcaccctgc attacatgtg tttattcatc
1621 cagcagtgtt gctcagctcc tacctctgtg ccagggcagc attttcatat ccaagatcaa
1681 ttccctctct cagcacagcc tggggagggg gtcattgttc tcctcgtcca tcagggattt
1741 cagaggctca gagactgcaa gctgcttgcc caagtcacac agctagtgaa gaccagagca
1801 gtttcatctg gttgtgactc taagctcagt gctctctcca ctaccccaca ccagccttgg
1861 tgccaccaaa agtgctcccc aaaaggaagg agaatgggat ttttcttttg aggcatgcac
1921 atctggaatt aaggtcaaac taattctcac atccctctaa aagtaaacta ctgttaggaa
1981 cagcagtgtt ctcacagtgt ggggcagccg tccttctaat gaagacaatg atattgacac
2041 tgtccctctt tggcagttgc attagtaact ttgaaaggta tatgactgag cgtagcatac
2101 aggttaacct gcagaaacag tacttaggta attgtagggc gaggattata aatgaaattt
2161 gcaaaatcac ttagcagcaa ctgaagacaa ttatcaacca cgtggagaaa atcaaaccga
2221 gcagggctgt gtgaaacatg gttgtaatat gcgactgcga acactgaact ctacgccact
2281 ccacaaatga tgttttcagg tgtcatggac tgttgccacc atgtattcat ccagagttct
2341 taaagtttaa agttgcacat gattgtataa gcatgctttc tttgagtttt aaattatgta
2401 taaacataag ttgcatttag aaatcaagca taaatcactt caactgctaa aaaaaaaaaa
2461 aaaaaaaaaa aaaaaaaaa
//