LOCUS AF177377 5539 bp mRNA linear HUM 02-JUL-2001
DEFINITION Homo sapiens cytoplasmic protein mRNA, complete cds.
ACCESSION AF177377
VERSION AF177377.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5539)
AUTHORS Heidebrecht,H.J., Buck,F., Pollmann,M., Siebert,R. and
Parwaresch,R.
TITLE Cloning and localization of C2orf2(ropp120), a previously unknown
WD repeat protein
JOURNAL Genomics 68 (3), 348-350 (2000)
PUBMED 10995578
REFERENCE 2 (bases 1 to 5539)
AUTHORS Heidebrecht,H.J., Buck,F., Pollmann,M., Siebert,R. and
Parwaresch,R.
TITLE Direct Submission
JOURNAL Submitted (12-AUG-1999) Hematopathology, University of Kiel,
Michaelisstr.11, Kiel 24105, Germany
COMMENT On Jul 2, 2001 this sequence version replaced AF177377.1.
FEATURES Location/Qualifiers
source 1..5539
/db_xref="H-InvDB:HIT000072715"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="2"
/map="2p14-p13"
/cell_line="L428"
CDS 237..3182
/note="120kDa; strongly overexpressed during mitosis"
/codon_start=1
/product="cytoplasmic protein"
/protein_id="AAG09279.2"
/translation="MDGFAGSLDDSISAASTSDVQDRLSALESRVQQQEDEITVLKAA
LADVLRRLAISEDHVASVKKSVSSKGQPSPRAVIPMSCITNGSGANRKPSHTSAVSIA
GKETLSSAAKSGTEKKKEKPQGQREKKEESHSNDQSPQIRASPSPQPSSQPLQIHRQT
PESKNATPTKSIKRPSPAEKSHNSWENSDDSRNKLSKIPSTPKLIPKVTKTADKHKDV
IINQEGEYIKMFMRGRPITMFIPSDVDNYDDIRTELPPEKLKLEWAYGYRGKDCRANV
YLLPTGEIVYFIASVVVLFNYEERTQRHYLGHTDCVKCLAIHPDKIRIATGQIAGVDK
DGRPLQPHVRVWDSVTLSTLQIIGLGTFERGVGCLDFSKADSGVHLCVIDDSNEHMLT
VWDWQKKAKGAEIKTTNEVVLAVEFHPTDANTIITCGKSHIFFWTWSGNSLTRKQGIF
GKYEKPKFVQCLAFLGNGDVLTGDSGGVMLIWSKTTVEPTPGKGPKGVYQISKQIKAH
DGSVFTLCQMRNGMLLTGGGKDRKIILWDHDLNPEREIEVPDQYGTIRAVAEGKADQF
LVGTSRNFILRGTFNDGFQIEVQGHTDELWGLATHPFKDLLLTCAQDRQVCLWNSMEH
RLEWTRLVDEPGHCADFHPSGTVVAIGTHSGRWFVLDAETRDLVSIHTDGNEQLSVMR
YSIDGTFLAVGSHDNFIYLYVVSENGRKYSRYGRCTGHSSYITHLDWSPDNKYIMSNS
GDYEILYWDIPNGCKLIRNRSDCKDIDWTTYTCVLGFQVFGVWPEGSDGTDINALVRS
HNRKVIAVADDFCKVHLFQYPCSKAKAPSHKYSAHSSHVTNVSFTHNDSHLISTGGKD
MSIIQWKLVEKLSLPQNETVADTTLTKAPVSSTESVIQSNTPTPPPSQPLNETAEEES
RISSSPTLLENSLEQTVEPSEDHSEEESEEGSGDLGEPLYEEPCNEISKEQAKATLLE
DQQDPSPSS"
BASE COUNT 1701 a 1079 c 1204 g 1555 t
ORIGIN
1 ggagggaggc cgggcaggcg gctgagcggc gcggctctca acgtgacggg gaagtggttc
61 gggcggccgc ggcttactac cccagggcga acggacggac gacggaggcg ggagccggta
121 gccgagccgg gcgacctaga gaacgagcgg gtcaggctca gcgtcggcca ctctgtcggt
181 ccgctgaatg aagtgcccgc ccctctaagc ccggagcccg gcgctttccc cgcaagatgg
241 acggtttcgc cggcagtctc gatgatagta tttctgctgc aagtacttct gatgttcaag
301 atcgcctgtc agctcttgag tcacgagttc agcaacaaga agatgaaatc actgtgctaa
361 aggcggcttt ggctgatgtt ttgaggcgtc ttgcaatctc tgaagatcat gtggcctcag
421 tgaaaaaatc agtctcaagt aaaggccaac caagccctcg agcagttatt cccatgtcct
481 gtataaccaa tggaagtggt gcaaacagaa aaccaagtca taccagtgct gtctcaattg
541 caggaaaaga aactctttca tctgctgcta aaagtggtac agaaaaaaag aaagaaaaac
601 cacaaggaca gagagaaaaa aaagaggaat ctcattctaa tgatcaaagt ccacaaattc
661 gagcatcacc ttctccccag ccctcttcac aacctctcca aatacacaga caaactccag
721 aaagcaagaa tgctactccc accaaaagca taaaacgacc atcaccagct gaaaagtcac
781 ataattcttg ggaaaattca gatgatagcc gtaataaatt gtcgaaaata ccttcaacac
841 ccaaattaat accaaaagtt accaaaactg cagacaagca taaagatgtc atcatcaacc
901 aagaaggaga atatattaaa atgtttatgc gcggtcggcc aattaccatg ttcattcctt
961 ccgatgttga caactatgat gacatcagaa cggaactgcc tcctgagaag ctcaaactgg
1021 agtgggcata tggttatcga ggaaaggact gtagagctaa tgtttacctt cttccgaccg
1081 gggaaatagt ttatttcatt gcatcagtag tagtactatt taattatgag gagagaactc
1141 agcgacacta cctgggccat acagactgtg tgaaatgcct tgctatacat cctgacaaaa
1201 ttaggattgc aactggacag atagctggcg tggataaaga tggaaggcct ctacaacccc
1261 acgtcagagt gtgggattct gttactctat ccacactgca gattattgga cttggcactt
1321 ttgagcgtgg agtaggatgc ctggattttt caaaagcaga ttcaggtgtt catttatgtg
1381 ttattgatga ctccaatgag catatgctta ctgtatggga ctggcagaag aaagcaaaag
1441 gagcagaaat aaagacaaca aatgaagttg ttttggctgt ggagtttcac ccaacagatg
1501 caaataccat aattacatgc ggtaaatctc atattttctt ctggacctgg agcggcaatt
1561 cactaacaag aaaacaggga atttttggga aatatgaaaa gccaaaattt gtgcagtgtt
1621 tagcattctt ggggaatgga gatgttctta ctggagactc aggtggagtc atgcttatat
1681 ggagcaaaac tactgtagag cccacacctg ggaaaggacc taaaggtgta tatcaaatca
1741 gcaaacaaat caaagctcat gatggcagtg tgttcacact ttgtcagatg agaaatggga
1801 tgttattaac tggaggaggg aaagacagaa aaataattct gtgggatcat gatctgaatc
1861 ctgaaagaga aatagaggtt cctgatcagt atggcacaat cagagctgta gcagaaggaa
1921 aggcagatca atttttagta ggcacatcac gaaactttat tttacgagga acatttaatg
1981 atggcttcca aatagaagta cagggtcata cagatgagct ttggggtctt gccacacatc
2041 ccttcaaaga tttgctcttg acatgtgctc aggacaggca ggtgtgcctg tggaactcaa
2101 tggaacacag gctggaatgg accaggctgg tagatgaacc aggacactgt gcagattttc
2161 atccaagtgg cacagtggtg gccataggaa cgcactcagg caggtggttt gttctggatg
2221 cagaaaccag agatctagtt tctatccaca cagacgggaa tgaacagctc tctgtgatgc
2281 gctactcaat agatggtacc ttcctggctg taggatctca tgacaacttt atttacctct
2341 atgtagtctc tgaaaatgga agaaaatata gcagatatgg aaggtgcact ggacattcca
2401 gctacatcac acaccttgac tggtccccag acaacaagta tataatgtct aactcgggag
2461 actatgaaat attgtactgg gacattccaa atggctgcaa actaatcagg aatcgatcgg
2521 attgtaagga cattgattgg acgacatata cctgtgtgct aggatttcaa gtatttggtg
2581 tctggccaga aggatctgat gggacagata tcaatgcact ggtgcgatcc cacaatagaa
2641 aggtgatagc tgttgccgat gacttttgta aagtccatct gtttcagtat ccctgctcca
2701 aagcaaaggc tcccagtcac aagtacagtg cccacagcag ccatgtcacc aatgtcagtt
2761 ttactcacaa tgacagtcac ctgatatcaa ctggtggaaa agacatgagc atcattcagt
2821 ggaaacttgt ggaaaagtta tctttgcctc agaatgagac tgtagcggat actactctaa
2881 ccaaagcccc cgtctcttcc actgaaagtg tcatccaatc taatactccc acaccgcctc
2941 cttctcagcc cttaaatgag acagctgaag aggaaagtag aataagcagt tctcccacac
3001 ttctggagaa cagcctggaa caaactgtgg agccaagtga agaccacagc gaggaggaga
3061 gtgaagaggg cagcggagac cttggtgagc ctctttatga agagccatgc aacgagataa
3121 gcaaggagca ggccaaagcc acccttctgg aggaccagca agacccttcg ccctcgtcct
3181 aacaccctgg cttcagtgca actcttttcc ttcagctgca tgtgattttg tgataaagtt
3241 caggtaacag gatgggcagt gatggagaat cactgttgat tgagattttg gtttccatgt
3301 gatttgtttt cttcaatagt cttattttca gtctctcaaa tacagccaac ttaaagtttt
3361 agtttggtgt ttattgaaaa ttaaccaaac ttaatactag gagaagactg aatcattaat
3421 gatgtctcac aaattactgt gtacctaagt ggtgtgatgt aaatactgga aacaaaaaca
3481 gcagttgcat tgattttgaa aacaaacccc cttgttatct gaacatgttt tcttcaggaa
3541 caaccagagg tatcacaaac actgttactc atctactggc tcagactgta ctactttttt
3601 tttttttttt cctgaaaaag aaaccagaaa aaaatgtact cttactgaga taccctctca
3661 ccccaaatgt gtaatggaaa atttttaatt aagaaaaact tcagttttgc caagtgcaat
3721 ggtgttgcct tctttaaaaa atgccgtttt cttacactac cagtggatgt ccagacatgc
3781 tcttagtcta ctagagaggt gctgcctttt ctaagtcata atgaggaaca gtcccttaat
3841 ttcttgtgtg caactctgtt ttatcctaga actaagagag cattggtttg ttaaagagct
3901 ttcaatgtat attaaaacct tcaatactca gaaatgatgg attcctccaa ggagtccttt
3961 actagcctaa acattctcaa atgtttgaga ttcaagtgaa tggaaggaaa accacatgcc
4021 tttaaaacta aactgtaata attacctggc taatttcagc taagccttca tcataatttg
4081 ttccctcagt aataggagaa atataaatac agtaagttta gattattgaa ttggtgcttg
4141 aaatttattg gttttgttgt aattttatac agattatatg agggataaga tactcatcaa
4201 attgcaaatt ctttttttta cagaagtgtg ggtaacagtc acagcagttt tttttaccaa
4261 cagcatactt aacagacttg ctgtgtagca gtttttttct ggtggagttg ctgtaagtct
4321 tgtaagtcta atgtggctat cctactcttt tgggcaatgc atgtattatg cattggaaag
4381 gtattttttt taagttctgt tggctagcta tggttttcag tacatttcct actttaagag
4441 taattactga caaatatgta tttcctatat gtttatactt tgattataaa aaagtatttt
4501 gttttgattt tttaacttgc tgcattgttt tgatactttc tatttttttg gtcaaatcat
4561 gtttagaaac tttggatgag ttaagaagtc ttaagtatgc aggcgtttac gtgattgtgc
4621 cattccaaag tgcatcagaa ctgtcattcc cttctaatat cttctcagga gtaatacaaa
4681 tcaggtattt catcatcatt tggtaatatg aaaactccag tgaactccca aggacattta
4741 caacatttat attcacacgc tgtatggaag ggtgtgggtg tgtgtgaagg ggcgagtgga
4801 gacactgtgt gtatctctag ataagaagat atgcaccacg ttgaaaatac tcagtgtaga
4861 tctctatgtg tataggtatc tgtatatctt tccttttgtt tacaactgtt aaaaaacctc
4921 aaaatagttc tcttcaaaag aagagagatt ccaagcaacc catctttctt cagtatgtat
4981 gttctgtaca tacttatcgg agcgcgccag taagtatcag gcatatatat ctgtctgtta
5041 gcaatgatta ttacatcatc agatcagcat gtgctatact ccctgcaaga aatatactga
5101 catgaacagg cagttcttgg agaagaaaga gcatttcttt aagtacctgg ggaatacagc
5161 tctcagtgat cagcagggag tttatttgag gacatcagtc acctttgggg ttgccatgta
5221 caatgagatt tataatcatg atactcttcg gtggtagttt caaaagacac tactaatacg
5281 caggaagcgt tccagctatt taatgctggc aactactgtt taatggtcag ttaaatctgt
5341 gataatggtt ggaagtgggt ggggttatga aattgtagat gtttttagaa aaacttgtga
5401 atgaaaatga atccaagtgt ttcatgtgaa gatgttgagc cattgctatc atgcattcct
5461 gtctcatggc agaaaatttt gaagattaaa aaataaaata atcaaaatgt ttcctctttc
5521 taaaaaaaaa aaaaaaaaa
//