LOCUS AF176313 1787 bp mRNA linear HUM 23-DEC-2016
DEFINITION Homo sapiens ADAM-TS related protein 1 (ADAMTSR1) mRNA, complete
cds.
ACCESSION AF176313
VERSION AF176313.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1787)
AUTHORS Hirohata,S., Wang,L.W., Miyagi,M., Yan,L., Seldin,M.F., Keene,D.R.,
Crabb,J.W. and Apte,S.S.
TITLE Punctin, a novel ADAMTS-like molecule, ADAMTSL-1, in extracellular
matrix
JOURNAL J. Biol. Chem. 277 (14), 12182-12189 (2002)
PUBMED 11805097
REFERENCE 2 (bases 1 to 1787)
AUTHORS Hirohata,S. and Apte,S.S.
TITLE A novel member of ADAM-TS related gene, ADAM-TSR1 (A
Disintegrin-like And Metalloproteinase domain with ThromboSpondin
type I modules Related gene-1)
JOURNAL Unpublished
REFERENCE 3 (bases 1 to 1787)
AUTHORS Hirohata,S. and Apte,S.S.
TITLE Direct Submission
JOURNAL Submitted (06-AUG-1999) Biomedical Engineering, The Cleveland
Clinic Foundation, 9500 Euclid Avenue, ND20, Cleveland, OH 44195,
USA
REFERENCE 4 (bases 1 to 1787)
AUTHORS Hirohata,S. and Apte,S.S.
TITLE Direct Submission
JOURNAL Submitted (23-DEC-2016) Biomedical Engineering, The Cleveland
Clinic Foundation, 9500 Euclid Avenue, ND20, Cleveland, OH 44195,
USA
REMARK Sequence update by database staff to remove vector contamination
COMMENT On Dec 23, 2016 this sequence version replaced AF176313.1.
FEATURES Location/Qualifiers
source 1..1787
/db_xref="H-InvDB:HIT000072650"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene 1..1787
/gene="ADAMTSR1"
/note="a disintegrin-like and metalloproteinase domain
with thrombospondin type I modules related gene-1"
CDS 35..1612
/gene="ADAMTSR1"
/note="ADAM-TSR1; does not contain metalloproteinase
domain"
/codon_start=1
/product="ADAM-TS related protein 1"
/protein_id="AAK84170.1"
/translation="MECCRRATPGTLLLFLAFLLLSSRTARSEEDRDGLWDAWGPWSE
CSRTCGGGAANSLRRCLSSKSCEGRNIRYRTCSNVDCPPEAGDFRAQQCSAHNDVKHH
GQFYEWLPVSNDPDNPCSLKCQAKGTTLVVELAPKVLDGTRCYTESLDMCISGLCQIV
GCDHQLGSTVKEDNCGVCNGDGSTCRLVRGQYKSQLSATKSDDTVVAIPYGSRHIRLV
LKGPDHLYLETKTLQGTKGENSLSSTGTFLVDNSSVDFQKFPDKEILRMAGPLTADFI
VKIRNSGSADSTVQFIFYQPIIHRWRETDFFPCSATCGGGYQLTSAECYDLRSNRVVA
DQYCHYYPENIKPKPKLQECNLDPCPASDGYKQIMPYDLYHPLPRWEATPWTACSSSC
GGGIQSRAVSCVEEDIQGHVTSVEEWKCMYTPKMPIAQPCNIFDCPKWLAQEWSPCTV
TCGQGLRYRVVLCIDHRGMHTGGCSPKTKPHIKEECIVPTPCYKPKEKLPVEAKLPWF
KQAQELEEGAAVSEEPS"
variation 194..199
/gene="ADAMTSR1"
/note="changes translation from ala-asn to ser-tyr"
/replace="tcctac"
BASE COUNT 471 a 456 c 451 g 409 t
ORIGIN
1 agtgtccgat tctgattccg gcaaggatcc aagcatggaa tgctgccgtc gggcaactcc
61 tggcacactg ctcctctttc tggctttcct gctcctgagt tccaggaccg cacgctccga
121 ggaggaccgg gacggcctat gggatgcctg gggcccatgg agtgaatgct cacgcacctg
181 cgggggtggg gccgccaact ctctgaggcg ctgcctgagc agcaagagct gtgaaggaag
241 aaatatccga tacagaacat gcagtaatgt ggactgccca ccagaagcag gtgatttccg
301 agctcagcaa tgctcagctc ataatgatgt caagcaccat ggccagtttt atgaatggct
361 tcctgtgtct aatgaccctg acaacccatg ttcactcaag tgccaagcca aaggaacaac
421 cctggttgtt gaactagcac ctaaggtctt agatggtacg cgttgctata cagaatcttt
481 ggatatgtgc atcagtggtt tatgccaaat tgttggctgc gatcaccagc tgggaagcac
541 cgtcaaggaa gataactgtg gggtctgcaa cggagatggg tccacctgcc ggctggtccg
601 agggcagtat aaatcccagc tctccgcaac caaatcggat gatactgtgg ttgcaattcc
661 ctatggaagt agacatattc gccttgtctt aaaaggtcct gatcacttat atctggaaac
721 caaaaccctc caggggacta aaggtgaaaa cagtctcagc tccacaggaa ctttccttgt
781 ggacaattct agtgtggact tccagaaatt tccagacaaa gagatactga gaatggctgg
841 accactcaca gcagatttca ttgtcaagat tcgtaactcg ggctccgctg acagtacagt
901 ccagttcatc ttctatcaac ccatcatcca ccgatggagg gagacggatt tctttccttg
961 ctcagcaacc tgtggaggag gttatcagct gacatcggct gagtgctacg atctgaggag
1021 caaccgtgtg gttgctgacc aatactgtca ctattaccca gagaacatca aacccaaacc
1081 caagcttcag gagtgcaact tggatccttg tccagccagt gacggataca agcagatcat
1141 gccttatgac ctctaccatc cccttcctcg gtgggaggcc accccatgga ccgcgtgctc
1201 ctcctcgtgt ggggggggca tccagagccg ggcagtttcc tgtgtggagg aggacatcca
1261 ggggcatgtc acttcagtgg aagagtggaa atgcatgtac acccctaaga tgcccatcgc
1321 gcagccctgc aacatttttg actgccctaa atggctggca caggagtggt ctccgtgcac
1381 agtgacgtgt ggccagggcc tcagataccg tgtggtcctc tgcatcgacc atcgaggaat
1441 gcacacagga ggctgtagcc caaaaacaaa gccccacata aaagaggaat gcatcgtacc
1501 cactccctgc tataaaccca aagagaaact tccagtcgag gccaagttgc catggttcaa
1561 acaagctcaa gagctagaag aaggagctgc tgtgtcagag gagccctcgt aagttgtaaa
1621 agcacagact gttctatatt tgaaactttt gtttaaagaa agcagtgtct cactggttgt
1681 agctttcatg ggttctgaac taagtgtaat catctcacca aagctttttg gctctcaaat
1741 taaagattga ttagtttcaa aaaaaaaaaa aaaaaagatg cggccgc
//