LOCUS AF176085 3054 bp mRNA linear HUM 29-SEP-2000
DEFINITION Homo sapiens neural polypyrimidine tract binding protein (PTB)
mRNA, complete cds.
ACCESSION AF176085
VERSION AF176085.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3054)
AUTHORS Markovtsov,V., Nikolic,J.M., Goldman,J.A., Turck,C.W., Chou,M.Y.
and Black,D.L.
TITLE Cooperative assembly of an hnRNP complex induced by a
tissue-specific homolog of polypyrimidine tract binding protein
JOURNAL Mol. Cell. Biol. 20 (20), 7463-7479 (2000)
PUBMED 11003644
REFERENCE 2 (bases 1 to 3054)
AUTHORS Markovtsov,V., Nikolic,J.M., Turck,C.W., Goldman,J.A. and
Black,D.L.
TITLE Direct Submission
JOURNAL Submitted (05-AUG-1999) Microbiology and Molecular Genetics,
HHMI/UCLA, 5-748 MacDonald Bldg, 675 Circle Dr S, Los Angeles, CA
90095-1662, USA
FEATURES Location/Qualifiers
source 1..3054
/db_xref="H-InvDB:HIT000072644"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="WERI-1"
/cell_type="retinoblastoma"
gene 1..3054
/gene="PTB"
CDS 53..1648
/gene="PTB"
/note="RNA binding protein; splicing regulator"
/codon_start=1
/product="neural polypyrimidine tract binding protein"
/protein_id="AAF14284.1"
/translation="MDGIVTEVAVGVKRGSDELLSGSVLSSPNSNMSSMVVTANGNDS
KKFKGEDKMDGAPSRVLHIRKLPGEVTETEVIALGLPFGKVTNILMLKGKNQAFLELA
TEEAAITMVNYYSAVTPHLRNQPIYIQYSNHKELKTDNTLNQRAQAVLQAVTAVQTAN
TPLSGTTVSESAVTPAQSPVLRIIIDNMYYPVTLDVLHQIFSKFGAVLKIITFTKNNQ
FQALLQYGDPVNAQQAKLALDGQNIYNACCTLRIDFSKLVNLNVKYNNDKSRDYTRPD
LPSGDGQPALDPAIAAAFAKETSLLAVPGALSPLAIPNAAAAAAAAAAGRVGMPGVSA
GGNTVLLVSNLNEEMVTPQSLFTLFGVYGDVQRVKILYNKKDSALIQMADGNQSQLAM
NHLNGQKMYGKIIRVTLSKHQTVQLPREGLDDQGLTKDFGNSPLHRFKKPGSKNFQNI
FPPSATLHLSNIPPSVAEEDLRTLFANTGGTVKAFKFFQDHKMALLQMATVEEAIQAL
IDLHNYNLGENHHLRVSFSKSTI"
BASE COUNT 922 a 522 c 602 g 1008 t
ORIGIN
1 tcggcacgag cgtggctcgg ttcttgtgag cgaagctttg tccggttcgg caatggacgg
61 aatcgtcact gaagttgcag ttggcgtgaa gagaggatct gacgaactac tctcaggcag
121 tgttctcagt agtccgaact ctaatatgag cagcatggta gttacagcca atggtaatga
181 tagtaaaaaa tttaaaggag aagataaaat ggatggtgct ccttctcgtg tacttcatat
241 tcgaaaatta cctggggaag taacagaaac tgaagttatt gctttaggct taccttttgg
301 taaggtgacc aacatcctta tgctgaaagg aaaaaatcag gcatttttgg aactagcaac
361 cgaggaagca gctattacta tggttaatta ctattctgct gtgacacctc atcttcgtaa
421 ccaaccaata tatatccagt actcgaatca caaagaacta aagacagata atacattaaa
481 ccaacgtgct caggcagttc ttcaagctgt gacagctgtc cagacagcaa atactcctct
541 tagtggcacc acagttagcg agagtgcagt gactccagcc cagagtccag tacttagaat
601 aattattgac aacatgtact accctgtaac acttgatgtt cttcaccaaa tattttctaa
661 gtttggtgct gtattgaaga taatcacatt tacaaaaaat aaccagtttc aagctttgct
721 ccagtatggt gatccagtaa atgctcaaca agcaaaacta gccctagatg gtcagaatat
781 ttataatgcc tgctgtaccc taaggattga tttttccaaa cttgtgaatt tgaatgtaaa
841 atacaacaat gataaaagta gggattatac tcgacctgat cttccatctg gggatggaca
901 acctgcattg gacccagcta ttgctgcagc atttgccaag gagacatccc tcttagctgt
961 tccaggagct ctgagtcctt tggccattcc aaatgctgct gcagcagctg ctgcagctgc
1021 tgctggccga gtgggtatgc ctggagtctc agctggtggc aatacagtcc tgttggttag
1081 caatttaaat gaagagatgg ttacgcccca aagtctgttt accctcttcg gtgtttatgg
1141 agatgtgcag cgtgtgaaga ttttatacaa taagaaagac agcgctctaa tacagatggc
1201 tgatggaaac caatcacaac ttgccatgaa tcatcttaat ggacagaaaa tgtatggaaa
1261 aattattcgt gttactctgt ctaaacatca gactgtacag ctacctcgag agggacttga
1321 tgatcaaggg ctaacaaaag attttggtaa ttccccattg catcgtttta agaaacctgg
1381 atccaaaaat tttcaaaaca tttttcctcc ttctgccacc cttcacctat ctaatatccc
1441 tccatcagta gcagaagagg atctacgaac actgttcgct aacactgggg gcactgtgaa
1501 agcatttaag ttttttcaag atcacaaaat ggctcttctt cagatggcaa cagtggaaga
1561 agctattcag gccttgattg atcttcataa ttataacctt ggagaaaacc atcatctgag
1621 agtgtctttc tccaagtcaa caatttaaaa atgggaagat gaagattggg ggtgaatcac
1681 attgttcaat gtcatcacct atttgactgt tcagaaaagt ggggaccaga gtttgatttt
1741 ttttgttttt gtttttttgg ggtttctttt ttttttccat gctgttatca ttccttggtt
1801 ataaaatgaa atggcatatg taaaggcaga gttgttaact gctatatttc atctgttcta
1861 tagggaagcc attttgtctg tttaaaattt cagtttaatt ttgctttttt tttttttttt
1921 tttttccttt caacttagtt gacatacgtg ccttaaaaag gaaaactagt gttgctattg
1981 tgcatttact agaaaaaagg aattggttgt ttagggcaca ctgttatatg ggaattaaaa
2041 tatgtttagg caggggtgtg taaaaaggtt aagtttttgt ttctcctggc ttggaactta
2101 ttttgaatta ctggcttgtc accttttttt ctatttaatc aaataagata catgatattg
2161 aaagaataaa gcagcatttt tagtttttac taccttaggc tttattgctt tgaaaacaac
2221 attggccttt tgtatctcac aattctggtc tagattcagt tatgaatgta ggcattagtt
2281 aaaattaaca agatgcagag tattaatttc ttaagacaac aaagtgattt ctgtaagttt
2341 gagccctatg tggaaagcat tgtggaatct taaccttttc gtacacactc ttgtgggacg
2401 tatcatataa atgtcagcac taagtaatgt cttgtttgtg gctgaatatt tttcgtagat
2461 gtttttgaag ttgacatgac ttacgtgcat ttaaatatat attgccatcc cttagtttgt
2521 aattaagatt tggaatatgg ttgtggattt ctgagcatgt gcagactggt ctagctagtt
2581 ccaggaactg gtgcatgtat ttttcaaaga taaagaaagt gtactgcgaa aatatgcagg
2641 aagattaatt ttgtggcagt tttctaaaac tgacaaccag gtgggaccaa agtttatgtg
2701 cctttagtct taatttacct tgcattgtaa tattcagttt taataaatct tcaaaatatt
2761 ttgtatttag gaatagatct gactttaata aaaacatggc tcagaatcta caggtcaaat
2821 taatttgaac agttcttgtc aatccgaatt gttgattctg tttaaatgac caatactttt
2881 tgaaattgat gtacttagtt tcaagattca tagattctgt tatctatgta gacagaatgg
2941 tcatgtatat tttctattag ttgagttttt acatctttag aaatgtaaaa ttcagtatag
3001 tttgaaagcg gcacaattaa aaattaattt tctaacaaaa aaaaaaaaaa aaaa
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