LOCUS AF175770 2239 bp mRNA linear HUM 27-AUG-2001
DEFINITION Homo sapiens suppressor of fused mRNA, complete cds.
ACCESSION AF175770
VERSION AF175770.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2239)
AUTHORS Kogerman,P., Grimm,T., Kogerman,L., Krause,D., Unden,A.B.,
Sandstedt,B., Toftgard,R. and Zaphiropoulos,P.G.
TITLE Mammalian suppressor-of-fused modulates nuclear-cytoplasmic
shuttling of Gli-1
JOURNAL Nat. Cell Biol. 1 (5), 312-319 (1999)
PUBMED 10559945
REFERENCE 2 (bases 1 to 2239)
AUTHORS Kogerman,P., Grimm,T., Kogerman,L., Krause,D., Unden,A.B.,
Sandstedt,B., Toftgard,R. and Zaphiropoulos,P.G.
TITLE Direct Submission
JOURNAL Submitted (05-AUG-1999) Bioscience, CNT, Karolinska Institute,
Novum, Huddinge S-141 57, Sweden
FEATURES Location/Qualifiers
source 1..2239
/db_xref="H-InvDB:HIT000072633"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 167..1621
/function="inhibitor of GLI1 mediated transcription"
/codon_start=1
/product="suppressor of fused"
/protein_id="AAD50501.1"
/translation="MAELRPSGAPGPTAPPAPGPTAPPAFASLFPPGLHAIYGECRRL
YPDQPNPLQVTAIVKYWLGGPDPLDYVSMYRNVGSPSANIPEHWHYISFGLSDLYGDN
RVHEFTGTDGPSGFGFELTFRLKRETGESAPPTWPAELMQGLARYVFQSENTFCSGDH
VSWHSPLDNSESRIQHMLLTEDPQMQPVQTPFGVVTFLQIVGVCTEELHSAQQWNGQG
ILELLRTVPIAGGPWLITDMRRGETIFEIDPHLQERVDKGIETDGSNLSGVSAKCAWD
DLSRPPEDDEDSRSICIGTQPRRLSGKDTEQIRETLRRGLEINSKPVLPPINPQRQNG
LPHDRAPSRKDSLESDSSTAIIPHELIRTRQLESVHLKFNQESGALIPLCLRGRLLHG
RHFTYKSITGDMAITFVSTGVEGAFATEEHPYAAHGPWLQILLTEEFVEKMLEDLEDL
TSPEEFKLPKEYSWPEKKLKVSILPDVVFDSPLH"
BASE COUNT 512 a 672 c 605 g 450 t
ORIGIN
1 gacagcctgg gcggacagtg cgccgtgcgc aggcgcggag ctagacctcg ctgcagcccc
61 catcgcctcg gggagtctca cccaccgagt ccgcccgctg gcccgtcagt gctctccccg
121 tcgtttgccc tctccagttc ccccagtgcc tgccctacgc accccgatgg cggagctgcg
181 gcctagcggc gcccccggcc ccaccgcgcc cccggcccct ggcccgactg cccccccggc
241 tttcgcttcg ctctttcccc cgggactgca cgccatctac ggagagtgcc gccgccttta
301 ccctgaccag ccgaacccgc tccaggttac cgctatcgtc aagtactggt tgggtggccc
361 agaccccttg gactatgtta gcatgtacag gaatgtgggg agcccttctg ctaacatccc
421 cgagcactgg cactacatca gcttcggcct gagtgatctc tatggtgaca acagagtcca
481 tgagtttaca ggaacagatg gacctagtgg ttttggcttt gagttgacct ttcgtctgaa
541 gagagaaact ggggagtctg ccccaccaac atggcccgca gagttaatgc agggcttggc
601 acgatacgtg ttccagtcag agaacacctt ctgcagtggg gaccatgtgt cctggcacag
661 ccctttggat aacagtgagt caagaattca gcacatgctg ctgacagagg acccacagat
721 gcagcccgtg cagacaccct ttggggtagt taccttcctc cagatcgttg gtgtctgcac
781 tgaagagcta cactcagccc agcagtggaa cgggcagggc atcctggagc tgctgcggac
841 agtgcctatt gctggcggcc cctggctgat aactgacatg cggaggggag agaccatatt
901 tgagatcgat ccacacctgc aagagagagt tgacaaaggc atcgagacag atggctccaa
961 cctgagtggt gtcagtgcca agtgtgcctg ggatgacctg agccggcccc ccgaggatga
1021 cgaggacagc cggagcatct gcatcggcac acagccccgg cgactctctg gcaaagacac
1081 agagcagatc cgggagaccc tgaggagagg actcgagatc aacagcaaac ctgtccttcc
1141 accaatcaac cctcagcggc agaatggtct cccccacgac cgggccccga gccgcaaaga
1201 cagcctggaa agtgacagct ccacggccat cattccccat gagctgattc gcacgcggca
1261 gcttgagagc gtacatctga aattcaacca ggagtccgga gccctcattc ctctctgcct
1321 aaggggcagg ctcctgcatg gacggcactt tacatataaa agtatcacag gtgacatggc
1381 catcacgttt gtctccacgg gagtggaagg cgcctttgcc actgaggagc atccttacgc
1441 ggctcatgga ccctggttac aaattctgtt gaccgaagag tttgtagaga aaatgttgga
1501 ggatttagaa gatttgactt ctccagagga attcaaactt cccaaagagt acagctggcc
1561 tgaaaagaag ctgaaggtct ccatcctgcc tgacgtggtg ttcgacagtc cgctacacta
1621 gcctgggctg ggccctgcag gggccagcag ggagcccagc tgctccccag tgacttccag
1681 tgtaacagtt gtgtcaacga gatctccaca aataaaagga caagtgtgag gaagactgcg
1741 cagtgccacc ccgcagccca gtggggtgcc atgcacaggc cacaggccct ccacctcacc
1801 tccagctcag gggccgcacc ccgccgctgg ctaagccttg tgacccatca ggccagtgag
1861 tgggcaaatg cggaccctcc ctgcctgcag cctgcacaga ttctggtttg aggtttgact
1921 ctggaccctg gctgtgccct aggtggagac agcctttttt ctaaccaacc ccctgccgca
1981 cagcccagca ggagggaggc ggacagccag atgcagaggg agtggatgca cttcccagct
2041 catttctgga agcctttgct actcaagctc ctctggccgc ggaacaattc ctctgatcat
2101 gtttggtttt cttcttcctt attttatttt gtagaaaccg ggtggtattt tattgctctg
2161 caaagatgtc cagaagccaa gtatataatg ttttttaaac aaaataaaaa aaaaaaaaaa
2221 aaaaaaaaaa ggaaaaaaa
//