LOCUS AF175267 1865 bp mRNA linear HUM 13-FEB-2001
DEFINITION Homo sapiens sorting nexin 15 (SNX15) mRNA, complete cds.
ACCESSION AF175267
VERSION AF175267.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1865)
AUTHORS Barr,V.A., Phillips,S.A., Taylor,S.I. and Haft,C.R.
TITLE Overexpression of a novel sorting nexin, SNX15, affects endosome
morphology and protein trafficking
JOURNAL Traffic 1 (11), 904-916 (2000)
PUBMED 11208079
REFERENCE 2 (bases 1 to 1865)
AUTHORS Phillips,S.A., Barr,V.A., Haft,D.H., Taylor,S.I. and Haft,C.R.
TITLE Identification and characterization of SNX15, a novel sorting nexin
involved in protein trafficking
JOURNAL J. Biol. Chem. 276 (7), 5074-5084 (2001)
PUBMED 11085978
REFERENCE 3 (bases 1 to 1865)
AUTHORS Phillps,S.A., Sierra,L., Barr,V.A., Taylor,S.I. and Renfrew Haft,C.
TITLE Sorting nexin 15 (SNX15): A novel sorting nexin with a possible
role in protein trafficking
JOURNAL Unpublished
REFERENCE 4 (bases 1 to 1865)
AUTHORS Renfrew Haft,C., Sierra,L. and Taylor,S.I.
TITLE Direct Submission
JOURNAL Submitted (04-AUG-1999) Diabetes Branch, National Institutes of
Health, 10 Center Dr., MSC-1770, Bethesda, MD 20892, USA
REFERENCE 5 (bases 1 to 1865)
AUTHORS Renfrew Haft,C., Sierra,L. and Taylor,S.I.
TITLE Direct Submission
JOURNAL Submitted (24-JAN-2001) Diabetes Branch, National Institutes of
Health, 10 Center Dr., MSC-1770, Bethesda, MD 20892, USA
REMARK Sequence update by submitter
COMMENT On Jan 24, 2001 this sequence version replaced AF175267.1.
FEATURES Location/Qualifiers
source 1..1865
/db_xref="H-InvDB:HIT000072621"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_type="tumor"
/tissue_type="parathyroid gland"
gene 1..1865
/gene="SNX15"
CDS 40..1068
/gene="SNX15"
/note="contains PX domain"
/codon_start=1
/product="sorting nexin 15"
/protein_id="AAF89955.1"
/translation="MSRQAKDDFLRHYTVSDPRTHPKGYTEYKVTAQFISKKDPEDVK
EVVVWKRYSDFRKLHGDLAYTHRNLFRRLEEFPAFPRAQVFGRFEASVIEERRKGAED
LLRFTVHIPALNNSPQLKEFFRGGEVTRPLEVSRDLHILPPPLIPTPPPDDPRLSQLL
PAERRGLEELEVPVDPPPSSPAQEALDLLFNCESTEEASGSPARGPLTEAELALFDPF
SKEEGAAPSPTHVAELATMEVESARLDQEPWEPGGQEEEEDGEGGPTPAYLSQATELI
TQALRDEKAGAYAAALQGYRDGVHVLLQGVPSDPLPARQEGVKKKAAEYLKRAEEILR
LHLSQLPP"
BASE COUNT 423 a 564 c 490 g 388 t
ORIGIN
1 ggtggaggcc ggcgctccgc tccgctccag ctcggtttca tgtcccgcca ggcgaaggat
61 gacttcctgc ggcactacac agtgtcggac cccaggactc accccaaggg ctacaccgag
121 tacaaagtaa ccgcgcagtt catctcaaag aaggacccag aggatgtcaa agaggtggtg
181 gtctggaagc ggtacagcga cttccgcaag ctgcatggag acctggccta cacccaccgc
241 aacctcttcc gccgcctcga ggagttcccc gctttccccc gggcccaggt gtttggccgg
301 tttgaagcct cagtgatcga ggagcggcga aagggggcag aggacctgct tcgcttcact
361 gtgcacatac ctgcgctcaa caacagcccc cagctcaagg agttcttccg gggtggggag
421 gtgacccgac ccttggaggt gtccagggac ctacacatcc tgccaccccc tctgatcccc
481 accccgcccc ctgatgaccc ccggctatcc caactgctcc ctgcagaaag gaggggcctc
541 gaggaattgg aggtgccagt ggacccccca ccatccagcc ctgcccagga ggccctggat
601 ctcctcttta actgtgagag caccgaggag gcatctggtt cccctgcccg aggccccctc
661 accgaggctg agcttgccct cttcgacccc ttctccaagg aagaaggcgc agcccccagc
721 cccacccatg tggctgagct ggcaacgatg gaggtggagt ctgcaaggct ggaccaggaa
781 ccctgggagc caggagggca ggaggaggaa gaggatgggg aaggagggcc cacccctgcc
841 tacctaagcc aggccacaga gctcatcacc caggccctgc gggatgagaa ggcaggcgct
901 tacgctgctg cactccaggg ctatcgagac ggcgtgcacg tcttgcttca gggagtcccc
961 agtgacccgt tgcctgcccg ccaggaaggt gtgaagaaga aggcagctga gtacctgaag
1021 cgggcagagg agatcctgcg cctgcacctg tctcaactcc caccctaaca gggagtgggc
1081 cattccctgg gactctcact cctgcactgc cagccccttc tcctctcccc agggcctggc
1141 cctacctcct ggtcttgtaa ttacaggagc catttctgta ggtaactgga ccaagaatga
1201 gaaaaataat gaattcttag ctccctgatt acacctgcca ccttggaatc caggactcac
1261 acttctgacc ctgcctgtct ttttggggtt tttttgagtt ggagtctcgc tgtgtcgccc
1321 agactggagt gcagtggtgg gatcacggct cactgcaacc tccacctccc aggttcaagc
1381 agttctcctg tctcagcctc cccagtagct gagattgcag gcacatgcca ccacgcccag
1441 ctaatatttt gtattttcag tagggacggg gttacaccat gttggccagg ctggtctcga
1501 actcctgacc tcaagtgatc cacccgcctc agtctcccaa agtgctgaga ttacaggcat
1561 gagtcactac gcccggccca tgtctgtctg tcttgatgtg tgagcagcag ctgtggtcat
1621 taaaccatta gtttacccct ctagaactgg ggtctgcaaa ctcccacctg cagccaaatc
1681 tggcccacct cctttttaat gtaagggctg tgagagtggt ttttactttt tttaatgatt
1741 aaaaaaatca aaataatatt ctgtgacaat gacaggtgaa atttatatgt gacaagtgaa
1801 aattatatga aatttaagag tccataaata aaatttgttg gaacacaaaa aaaaaaaaaa
1861 aaaaa
//