LOCUS AF173856 3472 bp mRNA linear HUM 28-MAR-2000
DEFINITION Homo sapiens Gemin4 mRNA, complete cds.
ACCESSION AF173856
VERSION AF173856.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3472)
AUTHORS Charroux,B., Pellizzoni,L., Perkinson,R.A., Yong,J., Shevchenko,A.,
Mann,M. and Dreyfuss,G.
TITLE Gemin4. A novel component of the SMN complex that is found in both
gems and nucleoli
JOURNAL J. Cell Biol. 148 (6), 1177-1186 (2000)
PUBMED 10725331
REFERENCE 2 (bases 1 to 3472)
AUTHORS Charroux,B., Shevchenko,A., Mann,M. and Dreyfuss,G.
TITLE Direct Submission
JOURNAL Submitted (28-JUL-1999) Biochemistry, HHMI, 415 Curie Boulevard,
Philadelphia, PA 19104-6148, USA
FEATURES Location/Qualifiers
source 1..3472
/db_xref="H-InvDB:HIT000072457_03"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 24..3200
/note="no homology; component of the spinal muscular
atrophy gene product complex; associated with snRNAs and
Sm proteins"
/codon_start=1
/product="Gemin4"
/protein_id="AAF35283.1"
/translation="MDLGPLNICEEMTILHGGFLLAEQLFHPKALAELTKSDWERVGR
PIVEALREISSAAAHSQPFAWKKKALIIIWAKVLQPHPVTPSDTETRWQEDLFFSVGN
MIPTINHTILFELLKSLEASGLFIQLLMALPTTICHAELERFLEHVTVDTSAEDVAFF
LDIWWEVMKHKGHPQDPLLSQFSAMAHKYLPALDEFPHPPKRLRSDPDACPTMPLLAM
LLRGLTQIQSRILGPGRKCCALANLADMLTVFALTEDDPQEVSATVYLDKLATVISVW
NSDTQNPYHQQALAEKVKEAERDVSLTSLAKLPSETIFVGCEFLHHLLREWGEELQAV
LRSSQGTSYDSYRLCDSLTSFSQNATLYLNRTSLSKEDRQVVSELAECVRDFLRKTST
VLKNRALEDITASIAMAVIQQKMDRHMEVCYIFASEKKWAFSDEWVACLGSNRALFRE
PDLVLRLLETVIDVSTADRAIPESQIRQVIHLILECYADLSLPGKNKVLAGILRSWGR
KGLSEKLLAYVEGFQEDLNTTFNQLTQSASEQGLAKAVASVARLVIVHPEVTVKKMCS
LAVVNLGTHKFLAQILTAFPALRFVEVQGPNSSATFMVSCLKETVWMKFSTPKEEKQF
LELLNCLMSPVKPQGIPVAALLEPDEVLKEFVLPFLRLDVEEVDLSLRIFIQTLEANA
CREEYWLQTCSPFPLLFSLCQLLDRFSKYWPLPKEKRCLSLDRKDLAIHILELLCEIV
SANAETFSPDVWIKSLSWLHRKLEQLDWTVGLRLKSFFEGHFKCEVPATLFEICKLSE
DEWTSQAHPGYGAGTGLLAWMECCCVSSGISERMLSLLVVDVGNPEEVRLFSKGFLVA
LVQVMPWCSPQEWQRLHQLTRRLLEKQLLHVPYSLEYIQFVPLLNLKPFAQELQLSVL
FLRTFQFLCSHSCRNWLPLEGWNHVVKLLCGSLTRLLDSVRAIQAAGPWVQGPEQDLT
QEALFVYTQVFCHALHIMAMLHPEVCEPLYVLALETLTCYETLSKTNPSVSSLLQRAH
EQRFLKSIAEGIGPEERRQTLLQKMSSF"
BASE COUNT 770 a 976 c 956 g 770 t
ORIGIN
1 tggcggccgc cggcgtcgcc gccatggacc taggaccctt gaacatctgt gaagaaatga
61 ctattctgca tggaggcttc ttgctggccg agcagctgtt ccaccctaag gcactggcag
121 aattaacaaa gtctgactgg gaacgtgttg gacggcccat cgtggaggcc ttaagggaga
181 tctcctcggc tgcagcacac tcccagccct ttgcctggaa gaagaaagcc ctgatcatca
241 tctgggccaa ggttctgcag ccgcaccccg tgaccccgtc cgacacagag acacggtggc
301 aggaagacct gttcttctcg gtgggcaaca tgatccccac catcaaccac accatcctct
361 tcgagctgct caaatccctg gaagcttctg gactctttat ccagctcctg atggccctgc
421 ccaccaccat ctgccatgca gaactagagc gctttctgga acatgtgacc gttgacactt
481 ctgccgaaga cgtggccttc ttcctggaca tctggtggga ggtgatgaag cacaagggtc
541 acccgcagga ccccctgctc tcccagttta gtgcaatggc ccataagtac ctgcctgcct
601 tagatgagtt cccccatcct ccaaagaggc ttaggtcaga cccagacgcg tgccccacca
661 tgcccctgtt ggccatgctg ctccgcgggc tgacacagat ccagagtcgg atcctgggcc
721 cggggaggaa gtgctgtgcg ctggccaacc tggctgacat gctgactgtg tttgcgctga
781 cagaggacga cccccaggag gtgtctgcaa ccgtgtatct ggacaaactg gccacggtga
841 tctctgtgtg gaactcggac acccagaatc cctaccacca gcaggcgctg gcagagaagg
901 tgaaggaggc agaacgggat gtcagcctga cctcgctggc caaactcccc agtgagacca
961 ttttcgtggg ctgcgagttc ctgcaccacc tgctgcggga gtggggggag gagttgcagg
1021 ccgtgctccg cagcagccag gggacaagtt acgacagcta ccggctgtgc gacagtctga
1081 cttccttcag ccagaacgcg acgctctacc tgaaccgcac cagcctgtcc aaggaggaca
1141 ggcaggtggt ctctgagctg gcggagtgtg tcagggactt cctgaggaaa acgagcacgg
1201 tgctgaagaa cagggccttg gaggatatca cagcttccat tgccatggcc gtcatccagc
1261 agaagatgga ccgccatatg gaagtgtgct acatttttgc ctctgagaag aagtgggcct
1321 tctcggacga gtgggtagcc tgcctgggga gtaacagggc cctcttccga gagccagact
1381 tggtgttgag gctgctggaa acagtgatag acgtcagcac agctgacaga gccatccctg
1441 agtctcagat ccggcaggtg atccacctga tcctggaatg ttacgcagac ctctccctgc
1501 caggtaaaaa taaagtcctt gcaggtatcc tgcgttcctg ggggcgaaag ggcctctctg
1561 aaaagttgct ggcttatgtg gagggttttc aggaagacct caatacaact tttaaccagc
1621 tcactcagag tgcctccgaa cagggcttgg caaaagctgt ggcctccgtg gcccgcctgg
1681 tcatagtgca cccggaagtc acggtgaaga aaatgtgcag cctggctgtg gtcaatctcg
1741 gcacccacaa gttcctggcc cagattctca ctgccttccc tgcccttagg tttgtggaag
1801 tgcagggtcc caattcatct gccactttca tggtgtcatg cctcaaagaa accgtctgga
1861 tgaagttctc tacacccaag gaagaaaagc aatttttaga gctcctgaac tgcctgatga
1921 gtcccgtgaa accccaaggg attccagtgg ctgctcttct tgagccagac gaggtgctga
1981 aggaatttgt cctgcctttc ttgaggttag atgttgaaga ggtagacctc agtctgagga
2041 tcttcatcca gactctagag gcaaacgcgt gccgagagga atactggctc cagacctgct
2101 ccccgtttcc actcctcttc agcttgtgcc agctcttgga ccgctttagc aaatactggc
2161 cgcttcccaa ggagaagcgg tgcctctctt tggataggaa ggatctagcg atccatatcc
2221 tggagctcct gtgtgagatt gtatcagcca atgctgagac cttctccccg gatgtctgga
2281 tcaagtccct gtcctggctc caccgcaagt tagaacagct agactggact gtgggcctga
2341 ggctgaagag cttcttcgag gggcacttca agtgtgaagt gccagccaca ctttttgaga
2401 tctgtaagct ttcagaagac gagtggacct cccaggccca cccagggtac ggggctggca
2461 cggggctcct ggcctggatg gagtgctgct gcgtctccag cggcatctcg gagaggatgc
2521 tgtctctctt ggtggtggac gtgggcaatc ctgaggaggt cagactgttc agcaaaggct
2581 ttctggtggc cctggtgcaa gtcatgcctt ggtgcagccc tcaggagtgg cagcgccttc
2641 accagctgac caggagactg ctggagaagc agctcctcca tgtcccttat agcctggaat
2701 atattcagtt tgttcccctg ctcaacctga agccctttgc ccaggagttg caactctccg
2761 tcctcttcct gaggactttc cagtttctct gcagccatag ctgtcgtaat tggcttcctc
2821 tggaaggctg gaaccacgtg gtcaaactcc tctgtggcag tctgacccgc ctcctggact
2881 cagtcagggc gatacaggca gctggccctt gggttcaagg accagagcag gacctgaccc
2941 aggaagccct gtttgtttac acccaggtgt tctgccatgc tctgcacatc atggccatgc
3001 tccacccgga ggtctgtgag ccactctacg ttttagcctt ggaaaccctc acctgctatg
3061 agactttgag caagaccaac ccttctgtca gctccttgct ccagagggca cacgagcagc
3121 gcttcttaaa gtccattgct gagggcattg gccctgaaga acggcgccaa accctgttgc
3181 agaagatgag cagcttctga cttggcgtgg ggagctgggc cccaacatgg cgggtctgca
3241 gaagatcagc agcttcttac ctgtgcggga gcgaaaaagc tgggcttcaa catggcaggt
3301 ctgtaggggt cagacccgag cagcctggac tttacagtta tgtgaaactg tccacaaaaa
3361 gtcatggcaa taatggtgta aagaaaatag tttcttgggt atttgtaacg tacaaactat
3421 cataaaaatt ctcctctttc gcatctcaaa aaaaaaaaaa aaaaaaaaaa aa
//