LOCUS AF169257 3637 bp mRNA linear HUM 14-JUL-2016
DEFINITION Homo sapiens potassium-dependent Na/Ca exchanger NCKX3 (SLC24A3)
mRNA, partial cds.
ACCESSION AF169257
VERSION AF169257.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3637)
AUTHORS Kraev,A., Quednau,B.D., Leach,S., Li,X.F., Dong,H., Winkfein,R.,
Perizzolo,M., Cai,X., Yang,R., Philipson,K.D. and Lytton,J.
TITLE Molecular cloning of a third member of the potassium-dependent
sodium-calcium exchanger gene family, NCKX3
JOURNAL J. Biol. Chem. 276 (25), 23161-23172 (2001)
PUBMED 11294880
REFERENCE 2 (bases 1 to 3637)
AUTHORS Kraev,A.S.
TITLE Direct Submission
JOURNAL Submitted (15-JUL-1999) Banting and Best Department of Medical
Research, University of Toronto, 112 College Street, Toronto, ON
M5G 1L6, Canada
REFERENCE 3 (bases 1 to 3637)
AUTHORS Kraev,A.S.
TITLE Direct Submission
JOURNAL Submitted (28-SEP-2000) Banting and Best Department of Medical
Research, University of Toronto, 112 College Street, Toronto, ON
M5G 1L6, Canada
REMARK Sequence update by submitter
REFERENCE 4 (bases 1 to 3637)
AUTHORS Kraev,A.S.
TITLE Direct Submission
JOURNAL Submitted (13-JUL-2001) Banting and Best Department of Medical
Research, University of Toronto, 112 College Street, Toronto, ON
M5G 1L6, Canada
REMARK Amino acid sequence updated by submitter
COMMENT On Sep 28, 2000 this sequence version replaced AF169257.1.
FEATURES Location/Qualifiers
source 1..3637
/db_xref="H-InvDB:HIT000072338"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="20"
/map="20p13"
/clone="HFBDW45"
/tissue_type="brain"
/clone_lib="Stratagene catalog #936206"
/dev_stage="fetus"
gene <1..3637
/gene="SLC24A3"
/note="solute carrier family 24 (sodium/potassium/calcium
exchanger), member 3; same gene as in GenBank Accession
Number AF288087"
CDS <1..1878
/gene="SLC24A3"
/function="ion transporter"
/note="similar to Mus musculus protein in GenBank
Accession Number AF314821 and to Rattus norvegicus protein
in GenBank Accession Number AY009158"
/codon_start=1
/product="potassium-dependent Na/Ca exchanger NCKX3"
/protein_id="AAG12988.2"
/translation="RDLLLSQLCFLASVALLLWSLSSLREQKELDLMDLVGEDRKWMM
ARKLMQVNDTLTSEDAGLRNSKNCTEPALHEFPNDIFTNEDRRQGAVVLHVLCAIYMF
YALAIVCDDFFVPSLEKICERLHLSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVG
VGTIVGSAVFNILCIIGVCGLFAGQVVALSSWCLLRDSIYYTLSVIALIVFIYDEKVS
WWESLVLVLMYLIYIVIMKYNACIHQCFERRTKGAGNMVNGLANNAEIDDSSNCDATV
VLLKKANFHRKASVIMVDELLSAYPHQLSFSEAGLRIMITSHFPPKTRLSMASRMLIN
ERQRLINSRAYTNGESEVAIKIPIKHTVENGTGPSSAPDRGVNGTRRDDVVAEAGNET
ENENEDNENDEEEEEDEDDDEGPYTPFDTPSGKLETVKWAFTWPLSFVLYFTVPNCNK
PRWEKWFMVTFASSTLWIAAFSYMMVWMVTIIGYTLGIPDVIMGITFLAAGTSVPDCM
ASLIVARQGMGDMAVSNSIGSNVFDILIGLGLPWALQTLAVDYGSYIRLNSRGLIYSV
GLLLASVFVTVFGVHLNKWQLDKKLGCGCLLLYGVFLCFSIMTEFNVFTFVNLPMCGD
H"
BASE COUNT 818 a 928 c 943 g 948 t
ORIGIN
1 agggaccttc tgctgagcca gctctgcttc ctggcctcgg tggcgctgct gctctggtcg
61 ctgtcgagcc tgcgagagca gaaggagctt gacctcatgg acctcgtagg ggaagacaga
121 aagtggatga tggcgaggaa gctgatgcag gtgaacgaca ctctgacttc cgaagatgcc
181 ggactccgga acagcaagaa ctgcaccgaa ccagccctgc atgaattccc caatgacatc
241 ttcacaaacg aggatagaag acaaggtgcg gtggtcctcc atgtgctctg tgccatatac
301 atgttctatg cgctggccat tgtgtgtgat gacttcttcg tcccttcctt ggaaaagatc
361 tgtgagcgcc tgcacctcag tgaagatgtg gctggggcca cattcatggc agcgggaagt
421 tcagccccag agctgttcac atcggtcata ggggtcttca tcaccaaagg cgatgtggga
481 gttggcacca tcgtgggctc agcggtattc aacatcctgt gcatcattgg tgtctgtggg
541 ctctttgctg ggcaggttgt ggctctttcc tcctggtgcc tgctgaggga ttctatttac
601 tacacgctgt ctgtgatcgc gctcatcgtg tttatttatg atgaaaaagt ttcctggtgg
661 gagtctttag tccttgtgct gatgtatctt atctacattg tcatcatgaa atataacgct
721 tgcatacatc agtgctttga gaggaggaca aaaggtgccg ggaacatggt caacggattg
781 gccaacaatg ctgaaattga tgacagcagc aactgcgacg caactgtggt gctacttaag
841 aaagcaaatt tccaccgcaa agcatcagtg atcatggtag acgagctgct gtcagcctac
901 ccacaccagc tttccttctc tgaggctggc cttcgaatca tgataaccag ccactttccc
961 cccaagaccc ggctctccat ggccagtcgc atgttgatca atgagagaca aagattgata
1021 aacagcaggg cttataccaa cggggaatct gaggtggcca tcaaaatccc aattaagcac
1081 accgtggaga atgggacagg gcccagcagt gccccagaca ggggcgtgaa tgggacacgg
1141 agggacgatg ttgtggctga ggctggcaac gaaacagaga atgaaaatga ggacaatgag
1201 aatgatgagg aggaagagga ggacgaggat gatgatgaag gaccgtacac accattcgac
1261 accccctcgg gtaaactgga aacagtgaaa tgggcgttca cctggccgct gagtttcgtc
1321 ttatacttca ctgtacccaa ctgcaacaag ccgcgctggg agaaatggtt catggtgacg
1381 tttgcttcct ccacgctgtg gatcgcagcc ttctcctaca tgatggtgtg gatggtcaca
1441 atcattggtt acaccctggg gattcctgac gtcatcatgg ggatcacctt cctggctgct
1501 gggaccagcg tgcctgactg catggccagc ctcattgtgg ccagacaagg gatgggggac
1561 atggctgtgt ccaactccat tgggagcaac gtgtttgaca tcctgattgg cctcggtctc
1621 ccctgggctc tgcagaccct ggctgtggat tacggatcct acatccggct gaatagcagg
1681 gggctgatct actccgtagg cttgctcctg gcctctgttt ttgtcacggt gttcggcgtc
1741 cacctgaaca agtggcagct ggacaagaag ctgggctgtg ggtgcctcct cctgtatggt
1801 gtgttcctgt gcttctccat catgactgag ttcaacgtgt tcacctttgt gaacctgccc
1861 atgtgcgggg accactgagc cgccgggtgc ccacagaggc tcagctcctt cttttctgtg
1921 caatacgaga cccggccgca ccccgagtca cacaggcccc cggggccacg gcgttcgtct
1981 ctcctgtgct gtcctcaggc ctccgctcct gttttggtgg cccaggctct cccctgcccc
2041 atcctcgctc ccccacctcc ttgggtcatg cccacccacc ctttcctgcc tcctccgtgt
2101 gaagacatcc aacatccacg tgacttttcc agctccattt ttaaacagtg actgagattc
2161 tagaaaaact ggctgctaac tggcctgagc caggcaacac tgattccaat ccctcctcct
2221 tttttaagtt atttgatgga agactcacct aatttgtgac ctgaaactgt tgaagaaata
2281 gagaggaggg ggcccgttga ttacagagag catttgggat tttgtttggt ttggagatga
2341 tgcctaggtt actgggtttg gggggattgt tttcttttgg gggccttccc cttttactcc
2401 ttttcttcca gagatcaaga gcttctcttg catcttcttc cactgggctc tggattaatc
2461 aattacccaa aggctgcacc tgccgtgttg tctgggcttg catcccagat gtgttggagt
2521 atgcatggat gtagtgcttt ttagaggagc cactgggcaa ggccaccaag aacaaatgca
2581 tgacatttta tagccaagga cgcctcgcta aagtcttatg ggcgtcccct ggggttgggg
2641 gggcacaagg ttttggagga agaagacaac ttccctcatt ccatcatcac catctctttc
2701 tcactaggtt ctttctagtt ttcaagcaat agttctagcc tgccttggac aagggggccc
2761 cagttaaaca aactacccat ccatgaggtg ccaggcagtc aaaaacagaa gcttccccga
2821 cttgtgagtc cctgagatgt gctcttgttg tttggcattt ggggtgacag ggagtgaccc
2881 agaggccacc actgcttttc atgcaggagt tacagacact ggtttcttgg aaaatggaga
2941 gaagcgcact ttgcacagac gtcgtcaatt aagtcccaat ttgccacttg gtattgagta
3001 cactggaccc tgaccactgg ctcttgggca aacgtccttc ctcacggggc gcctccgcca
3061 agccggccca gctgcacccc tcccttcctg gagggatggc cagggaagga gaaaacagag
3121 aactgacacc tttgaaacca cagaatgtgt tacatgcaga ctcgctcaag ggcataagtt
3181 attgtgaacg tttttgccaa tcactgctca acagccctgc tagattttgt atgatgctga
3241 attattatgc agactaattc cacccagttg agacacacca tgcttgttca cttgtattta
3301 ttgaaactgt ggattcttgc ccgtgctgtc ccttgtattt actttaagca ctgatcactt
3361 atcattcatt cggtatggtt ttccctgtcc cttgtacaca ttctggtatg aatttgtaaa
3421 aataacctgc tacaaattgg ttgaatgttt ctgtctgtgg tgcgaaccag cattaacgga
3481 tggggcacgt gcccaactga ggaacaggag aagaaatcac caatttgggc tctcagagct
3541 aagacacact tattgattct gttgcacatt ttgcactggt ttatggcgat tgttttcttg
3601 gacggatagt gtaaaataaa cttctctgtt ctctatc
//