LOCUS AF166003 2646 bp mRNA linear HUM 25-APR-2000
DEFINITION Homo sapiens voltage-gated potassium channel Kv4.1 (KCND1) mRNA,
complete cds.
ACCESSION AF166003
VERSION AF166003.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2646)
AUTHORS Isbrandt,D., Leicher,T., Waldschutz,R., Zhu,X., Luhmann,U.,
Michel,U., Sauter,K. and Pongs,O.
TITLE Gene structures and expression profiles of three human KCND (Kv4)
potassium channels mediating A-type currents I(TO) and I(SA)
JOURNAL Genomics 64 (2), 144-154 (2000)
PUBMED 10729221
REFERENCE 2 (bases 1 to 2646)
AUTHORS Isbrandt,D., Leicher,T., Waldschutz,R., Zhu,X., Luhmann,U.,
Michel,U., Sauter,K. and Pongs,O.
TITLE Direct Submission
JOURNAL Submitted (06-JUL-1999) Institut fuer Neurale Signalverarbeitung,
Zentrum fuer Molekulare Neurobiologie Hamburg, Martinistr. 52,
Hamburg 20246, Germany
FEATURES Location/Qualifiers
source 1..2646
/db_xref="H-InvDB:HIT000072275"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="HEK293"
/tissue_type="kidney"
/dev_stage="embryo"
gene 1..2646
/gene="KCND1"
5'UTR <1..50
/gene="KCND1"
CDS 51..1994
/gene="KCND1"
/note="Shal-related voltage-gated potassium channel"
/codon_start=1
/product="voltage-gated potassium channel Kv4.1"
/protein_id="AAF65516.1"
/translation="MAAGLATWLPFARAAAVGWLPLAQQPLPPAPGVKASRGDEVLVV
NVSGRRFETWKNTLDRYPDTLLGSSEKEFFYDADSGEYFFDRDPDMFRHVLNFYRTGR
LHCPRQECIQAFDEELAFYGLVPELVGDCCLEEYRDRKKENAERLAEDEEAEQAGDGP
ALPAGSSLRQRLWRAFENPHTSTAALVFYYVTGFFIAVSVIANVVETIPCRGSARRSS
REQPCGERFPQAFFCMDTACVLIFTGEYLLRLFAAPSRCRFLRSVMSLIDVVAILPYY
IGLLVPKNDDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLT
MAIIIFATVMFYAEKGTNKTNFTSIPAAFWYTIVTMTTLGYGDMVPSTIAGKIFGSIC
SLSGVLVIALPVPVIVSNFSRIYHQNQRADKRRAQQKVRLARIRLAKSGTTNAFLQYK
QNGGLEDSGSGEEQALCVRNRSAFEQQHHHLLHCLEKTTCHEFTDELTFSEALGAVSP
GGRTSRSTSVSSQPVGPGSLLSSCCPRRAKRRAIRLANSTASVSRGSMQELDMLAGLR
RSHAPQSRSSLNAKPHDSLDLNCDSRDFVAAIISIPTPPANTPDESQPSSPGGGGRAG
STLRNSSLGTPCLFPETVKISSL"
3'UTR 1995..>2646
/gene="KCND1"
BASE COUNT 516 a 838 c 723 g 569 t
ORIGIN
1 ctcctaaacg ccaccctcac taagtctccc tgggcttggg gagtggcacg atggcggcag
61 gcctggccac gtggctgcct tttgctcggg cagcagcagt gggctggctg cccctggccc
121 agcaacccct gcccccggca ccgggggtga aggcatctcg aggagatgag gttctggtgg
181 tgaacgtgag cggacggcgc tttgagactt ggaagaatac gctggaccgc tacccagaca
241 ccttgctggg cagctcggag aaggaattct tctacgatgc tgactcaggc gagtacttct
301 tcgatcgcga ccctgacatg ttccgccatg tgctgaactt ctaccgaacg gggcggctgc
361 attgcccacg gcaggagtgc atccaggcct tcgacgaaga gctggctttc tacggcctgg
421 ttcccgagct agtcggtgac tgctgccttg aagagtatcg ggaccgaaag aaggagaatg
481 ccgagcgcct ggcagaggat gaggaggcag agcaggccgg ggacggccca gccctgccag
541 caggcagctc cctgcggcag cggctctggc gggccttcga gaatccacac acgagcaccg
601 cagccctcgt tttctactat gtgaccggct tcttcatcgc cgtgtcggtc atcgccaatg
661 tggtggagac catcccatgc cgcggctctg cacgcaggtc ctcaagggag cagccctgtg
721 gcgaacgctt cccacaggcc tttttctgca tggacacagc ctgtgtactc atattcacag
781 gtgaatacct cctgcggctg tttgccgccc ccagccgttg ccgcttcctg cggagtgtca
841 tgagcctcat cgacgtggtg gccatcctgc cctactacat tgggcttttg gtgcccaaga
901 acgacgatgt ctctggcgcc tttgtcaccc tgcgtgtgtt ccgggtgttt cgcatcttca
961 agttctccag gcactcacag ggcttgagga ttctgggcta cacactcaag agctgtgcct
1021 ctgagctggg ctttctcctc ttttccctaa ccatggccat catcatcttt gccactgtca
1081 tgttttatgc tgagaagggc acaaacaaga ccaactttac aagcatccct gcggccttct
1141 ggtataccat tgtcaccatg accacgcttg gctacggaga catggtgccc agcaccattg
1201 ctggcaagat tttcgggtcc atctgctcac tcagtggcgt cttggtcatt gccctgcctg
1261 tgccagtcat tgtgtccaac tttagccgca tctaccacca gaaccagcgg gctgacaagc
1321 gccgagcaca gcagaaggtg cgcttggcaa ggatccggtt ggcaaagagt ggtaccacca
1381 atgccttcct gcagtacaag cagaatgggg gccttgagga cagcggcagt ggcgaggaac
1441 aggctctttg tgtcaggaac cgttctgcct ttgaacagca acatcaccac ttgctgcact
1501 gtctagagaa gacaacgtgc catgagttca cagatgagct caccttcagt gaagccctgg
1561 gagccgtctc gccgggtggc cgcaccagcc gtagcacctc tgtgtcttcc cagccagtgg
1621 gacccggaag cctgctgtct tcttgctgcc ctcgcagggc caagcgccgc gccatccgcc
1681 ttgccaactc cactgcctca gtcagccgtg gcagcatgca ggagctggac atgctggcag
1741 ggctgcgcag gagccatgcc cctcagagcc gctccagcct caatgccaag ccccatgaca
1801 gccttgacct gaactgcgac agccgggact tcgtggctgc cattatcagc atccctaccc
1861 ctcctgccaa caccccagat gagagccaac cttcctcccc tggcggcggt ggcagggccg
1921 gcagcaccct caggaactcc agcctgggta ccccttgcct cttccccgag actgtcaaga
1981 tctcatccct gtgaggggta ggcctgctga ttcagagggt cctcttcatt tttgggaact
2041 cctttccaaa gccatatttt tgggaggcag agaggggcag gcttgggcac cccttctgcc
2101 ccccccactg agaactatgc aatggagttt catgaaatgg tccacatagt ggggaagtag
2161 ccaggaaatg agaaacttcc tcccacccca gacatttttc ctggtgggag ctgaagcact
2221 gggcttccac aggcccctgg cctccttgcc ctagcacact gggactggcc ccactctccc
2281 agctggactc ctgcatgctc ctccccttgg gctctcagat gaaggcaaag ctttgatccg
2341 acatctgagc tctagcctaa gaaggagagt tgagatttcc tcctccctct ggctgggata
2401 tggagctttg gaggttcaga gaagagaacc ctcacctctg atctggcctc tacgagaggt
2461 cctcatctcc atctggccca acaattccca gattctgaag cttggaatgc aaacacaggc
2521 ttcatgggct gtggcctctg cagcgacctg ccatccccag gccttgcctg aggggtcagg
2581 ctgcctctcc caacacacac tcagatagca caaattctac catccccttc cctggctgct
2641 ggaaat
//