LOCUS AF163762 3400 bp mRNA linear HUM 14-JUL-2016
DEFINITION Homo sapiens zinc metalloendopeptidase (ADAMTS10) mRNA, partial
cds.
ACCESSION AF163762
VERSION AF163762.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3400)
AUTHORS Somerville,R.P., Jungers,K.A. and Apte,S.S.
TITLE Discovery and characterization of a novel, widely expressed
metalloprotease, ADAMTS10, and its proteolytic activation
JOURNAL J. Biol. Chem. 279 (49), 51208-51217 (2004)
PUBMED 15355968
REFERENCE 2 (bases 1 to 3400)
AUTHORS Apte,S.S.
TITLE ADAM-TS10: A novel member of the ADAM-TS family containing multiple
thrombospondin type I repeats
JOURNAL Unpublished
REFERENCE 3 (bases 1 to 3400)
AUTHORS Apte,S.S.
TITLE Direct Submission
JOURNAL Submitted (29-JUN-1999) Biomedical Engineering, Lerner Research
Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue,
Cleveland, OH 44195, USA
FEATURES Location/Qualifiers
source 1..3400
/db_xref="H-InvDB:HIT000072226"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene <1..3400
/gene="ADAMTS10"
/note="a disintegrin-like and metalloprotease domain with
thrombospondin type I repeats-10"
CDS <1..3234
/gene="ADAMTS10"
/codon_start=1
/product="zinc metalloendopeptidase"
/protein_id="AAG35563.1"
/translation="RSQDEFLSSLESYEIAFPTRVDHNGALLAFSPPPPRRQRRGTGA
TAESRLFYKVASPSTHFLLNLTRSSRLLAGHVSVEYWTREGLAWQRAARPHCLYAGHL
QGQASSSHVAISTCGGLHGLIVADEEEYLIEPLHGGPKGSRSPEESGPHVVYKRSSLR
HPHLDTACGVRDEKPWKGRPWWLRTLKPPPARPLGNETERGQPGLKRSVSRERYVETL
VVADKMMVAYHGRRDVEQYVLAIMNIVAKLFQDSSLGSTVNILVTRLILLTEDQPTLE
ITHHAGKSLDSFCKWQKSIVNHSGHGNAIPENGVANHDTAVLITRYDICIYKNKPCGT
LGLAPVGGMCERERSCSVNEDIGLPQAFTIAHEIGHTFGMNHDGVGNSCGARGQDPAK
LMAAHITMKTNPFVWSSCNRDYITSFLDSGLGLCLNNRPPRQDFVYPTVAPGQAYDAD
EQCRFQHGVKSRQCKYGEVCSELWCLSKSNRCITNSIPAAEGTLCQTHTIDKGWCYKR
VCVPFGSRPEGVDGAWGPWTPWGDCSRTCGGGVSSSSRHCDSPRPTIGGKYCLGERRR
HRSCNTDDCPPGSQDFREVQCSEFDSIPFRGKFYKWKTYRGGGVKACSLTSLAEGFNF
YTERAAAVVDGTPCRPDTVDICVSGECKHVGCDRVLGSDLREDKCRVCGGDGSACETI
EGVFSPASPGAGYEDVVWIPKGSVHIFIQDLNLSLSHLALKGDQESLLLEGLPGTPQP
HRLPLAGTTFQLRQGPDQVQSLEALGPINASLIVMVLARTELPALRYRFNAPIARDSL
PPYSWHYAPWTKCSAQCAGGSQVQAVECRNQLDSSAVAPHYCSAHSKLPKRQRACNTE
PCPPDWVVGNWSLCSRSCDAGVRSRSVVCQRRVSAAEEKALDDSACPQPRPPVLEACH
GPTCPPEWAALDWSECTPSCGPGLRHRVVLCKSADHRATLPPAHCSPAAKPPATMRCN
LRRCPPARWVAGEWGECSAQCGVGQRQRSVRCTSHTGQASHECTEALRPPTTQQCEAK
CDSPTPGDGPEECKDVNKVAYCPLVLKFQFCSRAYFRQMCCKTCQGH"
BASE COUNT 646 a 1117 c 1083 g 554 t
ORIGIN
1 cggtctcaag atgagttcct gtccagtctg gagagctatg agatcgcctt ccccacccgc
61 gtggaccaca acggggcact gctggccttc tcgccacctc ctccccggag gcagcgccgc
121 ggcacggggg ccacagccga gtcccgcctc ttctacaaag tagcctcgcc cagcacccac
181 ttcctgctga acctgacccg cagctcccgt ctactggcag ggcacgtctc cgtggagtac
241 tggacacggg agggcctggc ctggcagagg gcggcccggc cccactgcct ctacgctggt
301 cacctgcagg gccaggccag cagctcccat gtggccatca gcacctgtgg aggcctgcac
361 ggcctgatcg tggcagacga ggaagagtac ctgattgagc ccctgcacgg tgggcccaag
421 ggttctcgga gcccggagga aagtggacca catgtggtgt acaagcgttc ctctctgcgt
481 cacccccacc tggacacagc ctgtggagtg agagatgaga aaccgtggaa agggcggcca
541 tggtggctgc ggaccttgaa gccaccgcct gccagacccc tggggaatga aacagagcgt
601 ggccagccag gcctgaagcg atcggtcagc cgagagcgct acgtggagac cctggtggtg
661 gctgacaaga tgatggtggc ctatcacggg cgccgggatg tggagcagta tgtcctggcc
721 atcatgaaca ttgttgccaa acttttccag gactcgagtc tgggaagcac cgttaacatc
781 ctcgtaactc gcctcatcct gctcacggag gaccagccca ctctggagat cacccaccat
841 gccgggaagt ccctagacag cttctgtaag tggcagaaat ccatcgtgaa ccacagcggc
901 catggcaatg ccattccaga gaacggtgtg gctaaccatg acacagcagt gctcatcaca
961 cgctatgaca tctgcatcta caagaacaaa ccctgcggca cactaggcct ggccccggtg
1021 ggcggaatgt gtgagcgcga gagaagctgc agcgtcaatg aggacattgg cctgccacaa
1081 gcgttcacca ttgcccacga gatcgggcac acattcggca tgaaccatga cggcgtggga
1141 aacagctgtg gggcccgtgg tcaggaccca gccaagctca tggctgccca cattaccatg
1201 aagaccaacc cattcgtgtg gtcatcctgc aaccgtgact acatcaccag ctttctagac
1261 tcgggcctgg ggctctgcct gaacaaccgg ccccccagac aggactttgt gtacccgaca
1321 gtggcaccgg gccaagccta cgatgcagat gagcaatgcc gctttcagca tggagtcaaa
1381 tcgcgtcagt gtaaatacgg ggaggtctgc agcgagctgt ggtgtctgag caagagcaac
1441 cggtgcatca ccaacagcat cccggccgcc gagggcacgc tgtgccagac gcacaccatc
1501 gacaaggggt ggtgctacaa acgggtctgt gtcccctttg ggtcgcgccc agagggtgtg
1561 gacggagcct gggggccgtg gactccatgg ggcgactgca gccggacctg tggcggcggc
1621 gtgtcctctt ctagtcgtca ctgcgacagc cccaggccaa ccatcggggg caagtactgt
1681 ctgggtgaga gaaggcggca ccgctcctgc aacacggatg actgtccccc tggctcccag
1741 gacttcagag aagtgcagtg ttctgaattt gacagcatcc ctttccgtgg gaaattctac
1801 aagtggaaaa cgtaccgggg agggggcgtg aaggcctgct cgctcacgag cctagcggaa
1861 ggcttcaact tctacacgga gagggcggca gccgtggtgg acgggacacc ctgccgtcca
1921 gacacggtgg acatttgcgt cagtggcgaa tgcaagcacg tgggctgcga ccgagtcctg
1981 ggctccgacc tgcgggagga caagtgccga gtgtgtggcg gtgacggcag tgcctgcgag
2041 accatcgagg gcgtcttcag cccagcctca cctggggccg ggtacgagga tgtcgtctgg
2101 attcccaaag gctccgtcca catcttcatc caggatctga acctctctct cagtcacttg
2161 gccctgaagg gagaccagga gtccctgctg ctggaggggc tgcctgggac cccccagccc
2221 caccgtctgc ctctagctgg gaccaccttt caactgcgac aggggccaga ccaggtccag
2281 agcctcgaag ccctgggacc gattaatgca tctctcatcg tcatggtgct ggcccggacc
2341 gagctgcctg ccctccgcta ccgcttcaat gcccccatcg cccgtgactc gctgcccccc
2401 tactcctggc actatgcgcc ctggaccaag tgctcggccc agtgtgcagg cggtagccag
2461 gtgcaggcgg tggagtgccg caaccagctg gacagctccg cggtcgcccc ccactactgc
2521 agtgcccaca gcaagctgcc caaaaggcag cgcgcctgca acacggagcc ttgccctcca
2581 gactgggttg tagggaactg gtcgctctgc agccgcagct gcgatgcagg cgtgcgcagt
2641 cgctcggtcg tgtgccagcg ccgcgtctct gccgcggagg agaaggcgct ggacgacagc
2701 gcatgcccgc agccgcgccc acctgtactg gaggcctgcc acggccccac ttgccctccg
2761 gagtgggcgg ccctcgactg gtctgagtgc acccccagct gcgggccggg cctccgccac
2821 cgcgtggtcc tttgcaagag cgcagaccac cgcgccacgc tgcccccggc gcactgctca
2881 cccgccgcca agccaccggc caccatgcgc tgcaacttgc gccgctgccc cccggcccgc
2941 tgggtggctg gcgagtgggg tgagtgctct gcacagtgcg gcgtcgggca gcggcagcgc
3001 tcggtgcgct gcaccagcca cacgggccag gcgtcgcacg agtgcacgga ggccctgcgg
3061 ccgcccacca cgcagcagtg tgaggccaag tgcgacagcc caacccccgg ggacggccct
3121 gaagagtgca aggatgtgaa caaggtcgcc tactgccccc tggtgctcaa atttcagttc
3181 tgcagccgag cctacttccg ccagatgtgc tgcaaaacct gccagggcca ctagggggcg
3241 cgcggcaccc ggagccacag ctggcggggt ctccgccgcc agccctgcag cgggccggcc
3301 aaagggggcc ccgggggggc gggaactggg agggaagggt gagacggagc cggaagttat
3361 ttattgggaa cccctgcagg gccctggctg gggggatgga
//