LOCUS AF160973 4035 bp mRNA linear HUM 19-JUL-2001
DEFINITION Homo sapiens p53 inducible protein (PIR121) mRNA, complete cds.
ACCESSION AF160973
VERSION AF160973.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4035)
AUTHORS Saller,E., Tom,E., Brunori,M., Otter,M., Estreicher,A., Mack,D.H.
and Iggo,R.
TITLE Increased apoptosis induction by 121F mutant p53
JOURNAL EMBO J. 18 (16), 4424-4437 (1999)
PUBMED 10449408
REFERENCE 2 (bases 1 to 4035)
AUTHORS Saller,E. and Iggo,R.
TITLE Direct Submission
JOURNAL Submitted (21-JUN-1999) Oncogene Group, Swiss Institute for
Experimental Cancer Research, Ch. des Boveresses 155, Epalinges
CH-1066, Switzerland
FEATURES Location/Qualifiers
source 1..4035
/db_xref="H-InvDB:HIT000072061"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="5"
/map="5q34"
gene 1..4035
/gene="PIR121"
CDS 49..3810
/gene="PIR121"
/codon_start=1
/product="p53 inducible protein"
/protein_id="AAD45723.1"
/translation="MTTHVTLEDALSNVDLLEELPLPDQQPCIEPPPSSIMYQANFDT
NFEDRNAFVTGIARYIEQATVHSSMNEMLEEGHEYAVMLYTWRSCSRAIPQVKCNEQP
NRVEIYEKTVEVLEPEVTKLMKFMYFQRKAIERFCSEVKRLCHAERRKDFVSEAYLLT
LGKFINMFAVLDELKNMKCSVKNDHSAYKRAAQFLRKMADPQSIQESQNLSMFLANHN
RITQCLHQQLEVIPGYEELLADIVNICVDYYENKMYLTPSEKHMLLKVMGFGLYLMDG
NVSNIYKLDAKKRINLSKIDKFFKQLQVVPLFGDMQIELARYIKTSAHYEENKSKWTC
TQSSISPQYNICEQMVQIRDDHIRFISELARYSNSEVVTGSGLDSQKSDEEYRELFDL
ALRGLQLLSKWSAHVMEVYSWKLVHPTDKFCNKDCPGTAEEYERATRYNYTSEEKFAF
VEVIAMIKGLQVLMGRMESVFNQAIRNTIYAALQDFAQVTLREPLRQAVRKKKNVLIS
VLQAIRKTICDWEGGREPPNDPCLRGEKDPKGGFDIKVPRRAVGPSSTQLYMVRTMLE
SLIADKSGSKKTLRSSLDGPIVLAIEDFHKQSFFFTHLLNISEALQQCCDLSQLWFRE
FFLELTMGRRIQFPIEMSMPWILTDHILETKEPSMMEYVLYPLDLYNDSAYYALTKFK
KQFLYDEIEAEVNLCFDQFVYKLADQIFAYYKAMAGSVLLDKRFRAECKNYGVIIPYP
PSNRYETLLKQRHVQLLGRSIDLNRLITQRISAAMYKSLDQAISRFESEDLTSIVELE
WLLEINRLTHRLLCKHMTLDSFDAMFREANHNVSAPYGRITLHVFWELNFDFLPNYCY
NGSTNRFVRTAIPFTQEPQRDKPANVQPYYLYGSKPLNIAYSHIYSSYRNFVGPPHFK
TICRLLGYQGIAVVMEELLKIVKSLLQGTILQYVKTLIEVMPKICRLPRHEYGSPGIL
EFFHHQLKDIIEYAELKTDVFQSLREVGNAILFCLLIEQALSQEEVCDLLHAAPFQNI
LPRVYIKEGERLEVRMKRLEAKYAPLHLVPLIERLGTPQQIAIAREGDLLTKERLCCG
LSMFEVILTRIRSYLQDPIWRGPPPTNGVMHVDECVEFHRLWSAMQFVYCIPVGTNEF
TAEQCFGDGLNWAGCSIIVLLGQQRRFDLFDFCYHLLKVQRQDGKDEIIKNVPLKKMA
DRIRKYQILNNEVFAILNKYMKSVETDSSTVEHVRCFQPPIHQSLATTC"
BASE COUNT 1020 a 1110 c 1037 g 868 t
ORIGIN
1 tcccctggac ccgccgcaga gccagtgcag aatacagaaa ctgcagccat gaccacgcac
61 gtcaccctgg aagatgccct gtccaacgtg gacctgcttg aagagcttcc cctccccgac
121 cagcagccat gcatcgagcc tccaccttcc tccatcatgt accaggctaa ctttgacaca
181 aactttgagg acaggaatgc atttgtcacg ggcattgcaa ggtacattga gcaggctaca
241 gtccactcca gcatgaatga gatgctggag gaaggacatg agtatgcggt catgctgtac
301 acctggcgca gctgttcccg ggccattccc caggtgaaat gcaacgagca gcccaaccga
361 gtagagatct atgagaagac agtagaggtg ctggagccgg aggtcaccaa gctcatgaag
421 ttcatgtatt ttcagcgcaa ggccatcgag cggttctgca gcgaggtgaa gcggctgtgc
481 catgccgagc gcaggaagga ctttgtctct gaggcctacc tcctgaccct tggcaagttc
541 atcaacatgt ttgctgtcct ggatgagcta aagaacatga agtgcagcgt caagaatgac
601 cactctgcct acaagagggc agcacagttc ctgcggaaga tggcagatcc ccagtctatc
661 caggagtcgc agaacctttc catgttcctg gccaaccaca acaggatcac ccagtgtctc
721 caccagcaac ttgaagtgat cccaggctat gaggagctgc tggctgacat tgtcaacatc
781 tgtgtggatt actacgagaa caagatgtac ctgactccca gtgagaaaca tatgctcctc
841 aaggtgatgg gctttggcct ctacctaatg gatggaaatg tcagtaacat ttacaaactg
901 gatgccaaga agagaattaa tcttagcaaa attgataaat tctttaagca gctgcaggtg
961 gtgccccttt tcggcgacat gcagatagag ctggccagat acattaagac cagtgctcac
1021 tatgaagaga acaagtccaa gtggacgtgc acccagagca gcatcagccc ccagtacaat
1081 atctgcgagc agatggttca gatccgggat gaccacatcc gcttcatctc cgagctcgct
1141 cgctacagca acagtgaggt ggtgacgggc tcagggctgg acagccagaa gtcagacgag
1201 gagtatcgcg agctcttcga cctagccctg cggggtctgc agcttctatc caagtggagc
1261 gcccacgtca tggaggtgta ctcttggaag ctggttcatc ccacagacaa gttctgcaac
1321 aaggactgtc ctggcaccgc ggaggaatat gagagagcca cacgctacaa ttacaccagt
1381 gaggaaaaat ttgccttcgt tgaggtgatc gccatgatca aaggcctgca ggtgctcatg
1441 ggcaggatgg agagcgtctt caaccaggcc atcaggaaca ccatctacgc ggcattgcag
1501 gacttcgccc aggtgacgct gcgtgagccc ctgcggcagg cggtacggaa gaagaagaat
1561 gtcctcatca gcgtcctaca ggcaattcga aagaccatct gtgactggga gggagggcga
1621 gagcccccta atgacccatg cttgagaggg gagaaggacc ccaaaggtgg atttgatatc
1681 aaggtgcccc ggcgtgctgt ggggccatcc agcacacagc tgtacatggt gcggaccatg
1741 cttgaatcac tcattgcaga caaaagcggc tccaagaaga ccctgaggag cagcctggat
1801 ggacccattg tcctcgccat agaggacttt cacaaacagt ccttcttctt cacacatctg
1861 ctcaacatca gtgaagccct gcagcagtgt tgtgacctct cccagctctg gttccgagaa
1921 ttcttcctgg agttaaccat gggccgacga atccagttcc ccatcgagat gtccatgccc
1981 tggattctaa cggaccatat cctggaaacc aaagaacctt ccatgatgga gtatgtcctc
2041 taccctctgg atctgtacaa cgacagcgcc tactatgctc tgaccaagtt taaaaagcag
2101 ttcctgtacg atgagataga agctgaggtg aacctgtgtt ttgatcagtt tgtctacaag
2161 ctggcagacc agatctttgc ttactacaaa gccatggctg gcagtgtcct gttggataaa
2221 cgttttcgag ctgagtgtaa gaattatggc gtcatcattc cgtatccacc gtccaatcgc
2281 tatgaaacac tgctgaagca gagacacgtc cagctgttgg gtagatcaat tgacttgaac
2341 agactcatta cccagcgcat ctctgccgcc atgtataaat ccttggacca agctatcagc
2401 cgctttgaga gtgaggacct gacctccatt gtggagctgg agtggctgct ggagattaac
2461 cggctcacgc atcggctgct ctgtaagcat atgacgctgg acagcttcga tgccatgttc
2521 cgagaggcca atcacaatgt gtccgccccc tatggccgta tcaccctgca tgtcttctgg
2581 gaactgaact ttgactttct ccccaactac tgctacaatg ggtccactaa ccgttttgtg
2641 cggactgcca ttcctttcac ccaagaacca caacgagaca aacctgccaa cgtccagcct
2701 tattacctct atggatccaa gcctctcaac attgcctaca gccacatcta cagctcctac
2761 aggaatttcg tggggccacc tcatttcaag actatctgca gactcctggg ttatcagggc
2821 atcgctgtgg tcatggagga actgctaaag attgtgaaga gcttgctcca aggaaccatt
2881 ctccagtatg tgaaaacact gatagaggtg atgcccaaga tatgccgctt gccccgacat
2941 gagtatggct ccccagggat cctggagttc ttccaccacc agctgaagga catcattgag
3001 tacgcagagc tcaaaacaga cgtgttccag agcctgaggg aagtgggcaa tgccatcctc
3061 ttctgcctcc tcatagagca agctctgtct caggaggagg tctgcgattt gctccatgcc
3121 gcacccttcc aaaacatctt gcctagagtc tacatcaaag agggggagcg cctggaggtc
3181 cggatgaaac gtctggaagc caagtatgcc ccgctccacc tggtccctct gatcgagcgg
3241 ctggggaccc ctcagcaaat cgccattgct cgcgagggtg acctcctgac caaggagcgg
3301 ctgtgctgtg gcctgtccat gttcgaggtc atcctgaccc gcattcggag ctacctgcag
3361 gaccccatct ggcggggccc accgcccacc aatggcgtca tgcacgtcga tgagtgtgtg
3421 gagttccacc ggctgtggag cgccatgcag ttcgtgtact gcatccctgt gggaaccaac
3481 gagttcacag ctgagcagtg tttcggcgat ggcttgaact gggctggttg ctccatcatt
3541 gtcctgctgg gccagcagcg tcgctttgac ctgttcgact tctgttacca cctgctaaaa
3601 gtgcagaggc aggacgggaa ggatgaaatc attaagaatg tgcccctgaa gaagatggcc
3661 gaccggatca ggaagtatca gatcttgaac aatgaggttt ttgccatcct gaacaaatac
3721 atgaagtccg tggagacaga cagttccact gtggagcatg tgcgctgctt ccagccaccc
3781 atccaccagt ccttggccac cacttgctaa gcagaagatc ctgcagaccc ttatctggag
3841 gaggaagaga agcaggagag agaaagccac agccagcctg ccataggatc caactggaca
3901 acgtgtggga tggacctgga aacaagcacc tccccaaaca catcaccact ccctagggcg
3961 gggcctgtgc atgctctccc atgacatctc catgctggtt tctccatagc ataaatgaaa
4021 aaaaaaaaaa aaaaa
//