LOCUS AF159615 2040 bp mRNA linear HUM 16-DEC-1999
DEFINITION Homo sapiens FGF receptor activating protein 1 (FRAG1) mRNA,
complete cds.
ACCESSION AF159615
VERSION AF159615.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2040)
AUTHORS Lorenzi,M.V., Castagnino,P., Aaronson,D.C., Lieb,D.C., Lee,C.C.,
Keck,C.L., Popescu,N.C. and Miki,T.
TITLE Human FRAG1 encodes a novel membrane-spanning protein that
localizes to chromosome 11p15.5, a region of frequent loss of
heterozygosity in cancer
JOURNAL Genomics 62 (1), 59-66 (1999)
PUBMED 10585768
REFERENCE 2 (bases 1 to 2040)
AUTHORS Lorenzi,M.V.
TITLE Direct Submission
JOURNAL Submitted (16-JUN-1999) Laboratory of Cellular & Molecular Biology,
National Cancer Institute, Bldg. 37 Room 1E24, Bethesda, MD 20892,
USA
FEATURES Location/Qualifiers
source 1..2040
/db_xref="H-InvDB:HIT000072045"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="11"
/map="11p15.5"
/cell_line="M426"
/cell_type="embyronic fibroblasts"
gene 1..2040
/gene="FRAG1"
repeat_region 113..476
/gene="FRAG1"
/rpt_type=dispersed
CDS 129..1076
/gene="FRAG1"
/note="putative membrane spanning protein; similar to
membrane spanning proteins"
/codon_start=1
/product="FGF receptor activating protein 1"
/protein_id="AAF12755.1"
/translation="MYQVPLPLDRDGTLVRLRFTMVALVTVCCPLVAFLFCILWSLLF
HFKETTATHCGATPCRMFSAASQPLDPDGTLFRLRFTAMVWWAITFPVFGFFFCIIWS
LVFHFEYTVATDCGVPNYLPSVSSAIGGEVPQRYVWRFCIGLHSAPRFLVAFAYWNHY
LSCTSPCSCYRPLCRLNFGLNVVENLALLVLTYVSSSEDFTIHENAFIVFIASSLGHM
LLTCILWRLTKKHTVSQEDRKSYSWKQRLFIINFISFFSALAVYFRHNMYCEAGVYTI
FAILEYTVVLTNMAFHMTAWWDFGNKELLITSQPEEKRF"
BASE COUNT 442 a 611 c 480 g 507 t
ORIGIN
1 ggccttacca atcgcgaaaa cccgccgttc gcgctctgac cagcccgcag agccagcccc
61 cgaccccggg ccacctgggc ccccgggttc cgccggcact ctcgccacca ccgcgtgggt
121 ctgacaagat gtaccaggtc ccactaccac tggatcggga tgggaccctg gtacggctcc
181 gcttcaccat ggtggccctg gtcacggtct gctgtccact tgtcgccttc ctcttctgca
241 tcctctggtc cctgctcttc cacttcaagg agacaacggc cacacactgt ggggccacgc
301 cctgcaggat gttctctgcg gcctcccagc ctttggaccc cgatgggacc ttgttccggc
361 ttcgcttcac agccatggtc tggtgggcca tcacttttcc tgtgttcggc ttcttcttct
421 gcatcatctg gtccctggtg ttccactttg agtacacggt ggccactgac tgtggggtgc
481 ccaattacct gccctcggtg agctcagcca tcggcgggga ggtgccccag cgctacgtgt
541 ggcgtttctg catcggcctg cactcggcgc ctcgcttctt ggtggccttc gcctactgga
601 accactacct cagctgcacc tccccgtgtt cctgctatcg cccgctctgc cgcctcaact
661 tcggcctcaa tgtcgtggag aacctcgcgt tgctagtgct cacttatgtc tcctcctccg
721 aggacttcac catccacgaa aatgctttca ttgtgttcat tgcctcatcc ctcgggcaca
781 tgctcctcac ctgcattctc tggcggttga ccaagaagca cacagtaagt caggaggatc
841 gcaagtccta cagctggaaa cagcggctct tcatcatcaa cttcatctcc ttcttctcgg
901 cgctggctgt ctactttcgg cacaacatgt attgtgaggc tggagtgtac accatctttg
961 ccatcctgga gtacactgtt gtcttaacca acatggcgtt ccacatgacg gcctggtggg
1021 acttcgggaa caaggagctg ctcataacct ctcagcctga ggaaaagcga ttctgaaccc
1081 ttcagtcctg cttgggagga cgcagcccac tgcccagaaa caagaaacac gataccattc
1141 tggccttccc caccccacat cctctcttgg ccttactgaa gatgggggaa gggtaagaag
1201 gaagggtgta ggccaaggct caccccagtg ctgctggctt ctcctctcca cccctcatat
1261 gggcgtgggg tcctcaaaca tcacctttac ctgagaggcc ccaagaagct gagctggcag
1321 agagctccac catttggtgc taaaaaaaaa aacgtcctga ggttcatgac caccatccag
1381 tttctggcct ttacacagtc acctttcact gaggtcagga gcccctgagc agtggctgct
1441 ccctgacaac cacagccatt tctctgcacg ggggtcattc ataggactaa tgtatttcat
1501 gatctactgt gcacatccag gcctgtggcc acagtcccct gctaaagttg ctcaggtgtt
1561 ctagtcctga cttcaccttt ttgatttggt gtgtgcccta gggtatgtac ccttccccat
1621 ctgagcctcg gtgtgtccat gtgtctggcg ggggatgggt ggactgtatg atttccaagg
1681 actctaccag tcagtggttc tgatgtcatc gggtggaggt ggtgttctat acctaaagga
1741 tgacctgctc cagaaacagc accagcacag catgtatttt cttctcttct gaaagttctg
1801 gcttgtagac ccctcccctc ctttgcaaag gtatgggata gaggggtcag atgcagatct
1861 ctactgtaaa atgggctccc tggtatctcc tgtcttccct actgctccaa accctaaatt
1921 ttggttgtac attttatttt gaaaggaaaa taaatttttt ttttgggcca acaaaaaaaa
1981 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
//