LOCUS AF158185 2432 bp mRNA linear HUM 14-JUL-1999
DEFINITION Homo sapiens xeroderma pigmentosum variant RAD30 (RAD30) mRNA,
complete cds.
ACCESSION AF158185
VERSION AF158185.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2432)
AUTHORS Johnson,R.E., Kondratick,C.M., Prakash,S. and Prakash,L.
TITLE hRAD30 mutations in the variant form of xeroderma pigmentosum
JOURNAL Science 285 (5425), 263-265 (1999)
PUBMED 10398605
REFERENCE 2 (bases 1 to 2432)
AUTHORS Johnson,R.E., Kondratick,C.M., Prakash,S. and Prakash,L.
TITLE Direct Submission
JOURNAL Submitted (10-JUN-1999) Sealy Center for Molecular Science,
University of Texas Medical Branch at Galveston, 11th and Mechanic
Streets, Galveston, TX 77555-1061, USA
FEATURES Location/Qualifiers
source 1..2432
/db_xref="H-InvDB:HIT000072006"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="HeLa"
gene 1..2432
/gene="RAD30"
CDS 166..2307
/gene="RAD30"
/note="Saccharomyces cerevisiae RAD30-encoded Pol eta
homolog"
/codon_start=1
/product="xeroderma pigmentosum variant RAD30"
/protein_id="AAD43810.1"
/translation="MATGQDRVVALVDMDCFFVQVEQRQNPHLRNKPCAVVQYKSWKG
GGIIAVSYEARAFGVTRSMWADDAKKLCPDLLLAQVRESRGKANLTKYREASVEVMEI
MSRFAVIERASIDEAYVDLTSAVQERLQKLQGQPISADLLPSTYIEGLPQGPTTAEET
VQKEGMRKQGLFQWLDSLQIDNLTSPDLQLTVGAVIVEEMRAAIERETGFQCSAGISH
NKVLAKLACGLNKPNRQTLVSHGSVPQLFSQMPIRKIRSLGGKLGASVIEILGIEYMG
ELTQFTESQLQSHFGEKNGSWLYAMCRGIEHDPVKPRQLPKTIGCSKNFPGKTALATR
EQVQWWLLQLAQELEERLTKDRNDNDRVATQLVVSIRVQGDKRLSSLRRCCALTRYDA
HKMSHDAFTVIKNCNTSGIQTEWSPPLTMLFLCATKFSASAPSSSTDITSFLSSDPSS
LPKVPVTSSEAKTQGSGPAVTATKKATTSLESFFQKAAERQKVKEASLSSLTAPTQAP
MSNSPSKPSLPFQTSQSTGTEPFFKQKSLLLKQKQLNNSSVSSPQQNPWSNCKALPNS
LPTEYPGCVPVCEGVSKLEESSKATPAEMDLAHNSQSMHASSASKSVLEVTQKATPNP
SLLAAEDQVPCEKCGSLVPVWDMPEHMDYHFALELQKSFLQPHSSNPQVVSAVSHQGK
RNPKSPLACTNKRPRPEGMQTLESFFKPLTH"
BASE COUNT 683 a 593 c 551 g 605 t
ORIGIN
1 ctccgtcgtc acagggaata aatctcgctc gaaactcact ggaccgctcc tagaaaggcg
61 aaaagatatt caggagccct tccattttcc ttccagtagg caccgaaccc agcattttcg
121 gcaaccgctg ctggcagttt tgccaggtgt ttgttacctt gaaaaatggc tactggacag
181 gatcgagtgg ttgctctcgt ggacatggac tgtttttttg ttcaagtgga gcagcggcaa
241 aatcctcatt tgaggaataa accttgtgca gttgtacagt acaaatcatg gaagggtggt
301 ggaataattg cagtgagtta tgaagctcgt gcatttggag tcactagaag tatgtgggca
361 gatgatgcta agaagttatg tccagatctt ctactggcac aagttcgtga gtcccgtggg
421 aaagctaacc tcaccaagta ccgggaagcc agtgttgaag tgatggagat aatgtctcgt
481 tttgctgtga ttgaacgtgc cagcattgat gaggcttacg tagatctgac cagtgctgta
541 caagagagac tacaaaagct acaaggtcag cctatctcgg cagacttgtt gccaagcact
601 tacattgaag ggttgcccca aggccctaca acggcagaag agactgttca gaaagagggg
661 atgcgaaaac aaggcttatt tcaatggctc gattctcttc agattgataa cctcacctct
721 ccagacctgc agctcaccgt gggagcagtg attgtggagg aaatgagagc agccatagag
781 agggagactg gttttcagtg ttcagctgga atttcacaca ataaggtcct ggcaaaactg
841 gcctgtggac taaacaagcc caaccgccaa accctggttt cacatgggtc agtcccacag
901 ctcttcagcc aaatgcccat tcgcaaaatc cgtagtcttg gaggaaagct aggggcctct
961 gtcattgaga tcctagggat agaatacatg ggtgaactga cccagttcac tgaatcccag
1021 ctccagagtc attttgggga gaagaatggg tcttggctat atgccatgtg ccgagggatt
1081 gaacatgatc cagttaaacc caggcaacta cccaaaacca ttggctgtag taagaacttc
1141 ccaggaaaaa cagctcttgc tactcgggaa caggtacaat ggtggctgtt gcaattagcc
1201 caggaactag aggagagact gactaaagac cgaaatgata atgacagggt agccacccag
1261 ctggttgtga gcattcgtgt acaaggagac aaacgcctca gcagcctgcg ccgctgctgt
1321 gcccttaccc gctatgatgc tcacaagatg agccatgatg catttactgt catcaagaac
1381 tgtaatactt ctggaatcca gacagaatgg tctcctcctc tcacaatgct tttcctctgt
1441 gctacaaaat tttctgcctc tgccccttca tcttctacag acatcaccag cttcttgagc
1501 agtgacccaa gttctctgcc aaaggtgcca gttaccagct cagaagctaa gacccaggga
1561 agtggcccag cggtgacagc cactaagaaa gcaaccacgt ctctggaatc attcttccaa
1621 aaagctgcag aaaggcagaa agttaaagaa gcttcgcttt catctcttac tgctcccact
1681 caggctccca tgagcaattc accatccaag ccctcattac cttttcaaac cagtcaaagt
1741 acaggaactg agcccttctt taagcagaaa agtctgcttc taaagcagaa acagcttaat
1801 aattcttcag tttcttcccc ccaacaaaac ccatggtcca actgtaaagc attaccaaac
1861 tctttaccaa cagagtatcc agggtgtgtc cctgtttgtg aaggggtgtc gaagctagaa
1921 gaatcctcta aagcaactcc tgcagagatg gatttggccc acaacagcca aagcatgcac
1981 gcctcttcag cttccaaatc tgtgctggag gtgactcaga aagcaacccc aaatccaagt
2041 cttctagctg ctgaggacca agtgccctgt gagaagtgtg gctccctggt accggtatgg
2101 gatatgccag aacacatgga ctatcatttt gcattggagt tgcagaaatc ctttttgcag
2161 ccccactctt caaaccccca ggttgtttct gccgtatctc atcaaggcaa aagaaatccc
2221 aagagccctt tggcctgcac taataaacgc cccaggcctg agggcatgca aacattggaa
2281 tcatttttta agccattaac acattagtgc tgccctcagg cttgcctgta ggatttaata
2341 ttttttatct ttacagatct ttatctttaa tattttatct ttacagattt ccctgagaaa
2401 gggaattatg aaatttttaa tacaaaaaat aa
//