LOCUS AF157624 3989 bp mRNA linear HUM 06-MAR-2000
DEFINITION Homo sapiens Spacrcan mRNA, complete cds.
ACCESSION AF157624
VERSION AF157624.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3989)
AUTHORS Acharya,S., Foletta,V.C., Lee,J.W., Rayborn,M.E., Rodriguez,I.R.,
Young,W.S. III and Hollyfield,J.G.
TITLE SPACRCAN, a novel human interphotoreceptor matrix
hyaluronan-binding proteoglycan synthesized by photoreceptors and
pinealocytes
JOURNAL J. Biol. Chem. 275 (10), 6945-6955 (2000)
PUBMED 10702256
REFERENCE 2 (bases 1 to 3989)
AUTHORS Foletta,V.C. and Young,W.S.
TITLE Direct Submission
JOURNAL Submitted (09-JUN-1999) SNGE, NIMH, 36 Convent Dr, MSC 4068,
Bethesda, MD 20892-4068, USA
FEATURES Location/Qualifiers
source 1..3989
/db_xref="H-InvDB:HIT000072001"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="3"
/map="3q11.2"
CDS 15..3740
/note="hyaluronan-binding proteoglycan; interphotoreceptor
matrix component"
/codon_start=1
/product="Spacrcan"
/protein_id="AAF13154.1"
/translation="MIMFLLFGKISLGILIFVLIEGDFPSLTAQTYLSIEEIQEPKSA
VSFLLPEESTDLSLATKKKQPLDRRETERQWLTRRRRSILFPNGVKICPDESVAEAVA
NHVKYFKVRVCQEAVWEAFRTFWDRLPGREEYHYWMNLCEDGVTSIFEMGTNFSESVE
HRSLIMKKLTYAKETVSSSELSSPVPVGDTSTLGDTTLSVPHPEVDAYEGASESSLER
PEESISNEIENVIEEATKPAGEQIAEFSIHLLGKQYREELQDSSSFHHQHLEEEFISE
VENAFTGLPGYKEIRVLEFRSPKENDSGVDVYYAVTFNGEAISNTTWDLISLHSNKVE
NHGLVELDDKPTVVYTISNFRDYIAETLQQNFLLGNSSLNPDPDSLQLINVRGVLRHQ
TEDLVWNTQSSSLQATPSSILDNTFQAAWPSADESITSSIPPLDFSSGPPSATGRELW
SESPLGDLVSTHKLAFPSKMGLSSSPEVLEVSSLTLHSVTPAVLQTGLPVASEERTSG
SHLVEDGLANVEESEDFLSIDSLPSSSFTQPVPKETIPSMEDSDVSLTSSPYLTSSIP
FGLDSLTSKVKDQLKVSPFLPDASMEKELIFDGGLGSGSGQKVDLITWPWSETSSEKS
AEPLSKPWLEDDDSLLPAEIEDKKLVLVDKMDSTDQISKHSKYVHDDRSIHFPEEEPL
SGPAVPIFADTAAESASLTLPKHISEVPGVDDYSVTKAPLILTSVAISASTDKSDQAD
AILREDMEQITESSNYEWFDSEVSMVKPDMQTLWTILPESERVWTRTSSLEKLSRDIL
ASTPQSADRLWLSVTQSTKLPPTTISTLLEDEVIMGVQDISLELDRIGTDYYQPEQVQ
EQNGKVGSYVEMSTSVHSTEMVSVAWPTEGGDDLSYTQTSGALVVFFSLRVTNMMFSE
DLFNKNSLEYKALEQRFLELLVPYLQSNLTGFQNLEILNFRNGSIVVNSRMKFANSVP
PNVNNAVYMILEDFCTTAYNTMNLAIDKYSLDVESGDEANPCKFQACNEFSECLVNPW
SGEAKCRCFPGYLSVEERPCQSLCDLQPDFCLNDGKCDIMPGHGAICRCRVGENWWYR
GKHCEEFVSEPVIIGITIASVVGLLVIFSAIIYFFIRTLQAHHDRSERESPFSGSSRQ
PDSLSSIENAVKYNPVYESHRAGCEKYEGPYPQHPFYSSASGDVIGGLSREEIRQMYE
SSELSREEIQERMRVLELYANDPEFAAFVREQQVEEV"
BASE COUNT 1146 a 829 c 924 g 1090 t
ORIGIN
1 gggatttggc ccaaatgatt atgtttctcc tttttgggaa gatttctctg ggtattttga
61 tatttgtact gatagaagga gactttccat cattaacagc acaaacctac ttatctatag
121 aggagatcca agaacccaag agtgcagttt cttttctcct gcctgaagaa tcaacagacc
181 tttctctagc taccaaaaag aaacagcctc tggaccgcag agaaactgaa agacagtggt
241 taaccagaag gcggagatct attctgtttc ctaatggagt gaaaatctgc ccagatgaaa
301 gtgttgcaga ggctgtggca aatcatgtga agtattttaa agtccgagtg tgtcaggaag
361 ctgtctggga agccttcagg actttttggg atcgacttcc tgggcgtgag gaatatcatt
421 actggatgaa tttgtgtgag gatggagtca caagtatatt tgaaatgggc acaaatttta
481 gtgaatctgt ggaacataga agcttaatca tgaagaaact gacttatgca aaggaaactg
541 taagcagctc tgaactgtct tctccagttc ctgttggtga tacttcaaca ttgggagaca
601 ctactctcag tgttccacat ccagaggtgg acgcctatga aggtgcctca gagagcagct
661 tggaaaggcc agaggagagt attagcaatg aaattgagaa tgtgatagaa gaagccacaa
721 aaccagcagg tgaacagatt gcagaattca gtatccacct tttggggaag cagtacaggg
781 aagaactaca ggattcctcc agctttcacc accagcacct tgaagaagaa tttatttcag
841 aggttgaaaa tgcatttact gggttaccag gctacaagga aattcgtgta cttgaattta
901 ggtcccccaa ggaaaatgac agtggcgtag atgtttacta tgcagttacc ttcaatggtg
961 aggccatcag caataccacc tgggacctca ttagccttca ctccaacaag gtggaaaacc
1021 atggccttgt ggaactggat gataaaccca ctgttgttta tacaatcagt aacttcagag
1081 attatattgc tgagacattg cagcagaatt ttttgctggg gaactcttcc ttgaatccag
1141 atcctgattc cctgcagctt atcaatgtga gaggagtttt gcgtcaccaa actgaagatc
1201 tagtttggaa cacccaaagt tcaagtcttc aggcaacgcc gtcatctatt ctggataata
1261 cctttcaagc tgcatggccc tcagcagatg aatccatcac cagcagtatt ccaccacttg
1321 atttcagctc tggtcctccc tcagccactg gcagggaact ctggtcagaa agtcctttgg
1381 gtgatttagt gtctacacac aaattagcct ttccctcgaa gatgggcctc agctcttccc
1441 cagaggtttt agaggttagc agcttgactc ttcattctgt caccccggca gtgcttcaga
1501 ctggcttgcc tgtggcttct gaggaaagga cttctggatc tcacttggta gaagatggat
1561 tagccaatgt tgaagagtca gaagattttc tttctattga ttcattgcct tcaagttcat
1621 tcactcaacc tgtgccaaaa gaaacaatac catccatgga agactctgat gtgtccttaa
1681 catcttcacc atatctgacc tcttctatac cttttggctt ggactccttg acctccaaag
1741 tcaaagacca attaaaagtg agccctttcc tgccagatgc atccatggaa aaagagttaa
1801 tatttgacgg tggtttaggt tcagggtctg ggcaaaaggt agatctgatt acttggccat
1861 ggagtgagac ttcatcagag aagagcgctg aaccactgtc caagccgtgg cttgaagatg
1921 atgattcact tttgccagct gagattgaag acaagaaact agttttagtt gacaaaatgg
1981 attccacaga ccaaattagt aagcactcaa aatatgtaca tgatgacaga tccatacact
2041 ttccagagga agagcctctt agtgggcctg ctgtgcccat cttcgcagat actgcagctg
2101 aatctgcgtc tctaaccctc cccaagcaca tatcagaagt acctggtgtt gatgattact
2161 cagttaccaa agcacctctt atactgacat ctgtagcaat ctctgcctct actgataaat
2221 cagatcaggc agatgccatc ctaagggagg atatggaaca aattactgag tcatccaact
2281 atgaatggtt tgacagtgag gtttcaatgg taaagccaga tatgcaaact ttgtggacta
2341 tattgccaga atcagagaga gtttggacaa gaacttcttc cctagagaaa ttgtccagag
2401 acatattggc aagtacacca cagagtgctg acaggctctg gttatctgtg acacagtcta
2461 ccaaattgcc tccaaccaca atctccaccc tgctagagga tgaagtaatt atgggtgtac
2521 aggatatttc gttagaactg gaccggatag gcacagatta ctatcagcct gagcaagtcc
2581 aagagcaaaa tggcaaggtt ggtagttatg tggaaatgtc aacaagtgtt cactccacag
2641 agatggttag tgtggcttgg cccacagaag gaggagatga cttgagttat acccagactt
2701 caggagcttt ggtggttttc ttcagcctcc gagtgactaa catgatgttt tcagaagatc
2761 tgtttaataa aaactccttg gagtataaag ccctggagca aagattctta gaattgctgg
2821 ttccctatct ccagtcaaat ctcacggggt tccagaactt agaaatcctc aacttcagaa
2881 atggcagcat tgtggtgaac agtcgaatga agtttgccaa ttctgtccct cctaacgtca
2941 acaatgcggt gtacatgatt ctggaagact tttgtaccac tgcctacaat accatgaact
3001 tggctattga taaatactct cttgatgtgg aatcaggtga tgaagccaac ccttgcaagt
3061 ttcaggcctg taatgaattt tcagagtgtc tggtcaaccc ctggagtgga gaagcaaagt
3121 gcagatgctt ccctggatac ctgagtgtgg aagaacggcc ctgtcagagt ctctgtgacc
3181 tacagcctga cttctgcttg aatgatggaa agtgtgacat tatgcctggg cacggggcca
3241 tttgtaggtg ccgggtgggt gagaactggt ggtaccgagg caagcactgt gaggaatttg
3301 tgtctgagcc cgtgatcata ggcatcacta ttgcctccgt ggttggactt cttgtcatct
3361 tttctgctat catctacttc ttcatcagga ctcttcaagc acaccatgac aggagtgaaa
3421 gagagagtcc cttcagtggc tccagcaggc agcctgacag cctctcatct attgagaatg
3481 ctgtgaagta caaccccgtg tatgaaagtc acagggctgg atgtgagaag tatgagggac
3541 cctatcctca gcatcccttc tacagctctg ctagcggaga cgtgattggt gggctgagca
3601 gagaagaaat cagacagatg tatgagagca gtgagctttc cagagaggaa attcaagaga
3661 gaatgagagt tttggaactg tatgccaatg atcctgagtt tgcagctttt gtgagagagc
3721 aacaagtgga agaggtttaa ccaaaactcc tgttctgaaa ctgattagaa gcctggagaa
3781 gatggagatt acttgttact tatgtcatat aattaacctg gattttaaac actgttggaa
3841 gaagagtttt ctatgaaaaa attaaatata gggcacactg tttttttttc agcttaagtt
3901 ttcagaatgt agtaagagat gttaccattt ttatttctat aaagactgaa tgctgtgttt
3961 aaataaattg aaaactacct aaaaaaacg
//