LOCUS AF157492 3771 bp mRNA linear HUM 01-JUL-2000
DEFINITION Homo sapiens sodium bicarbonate cotransporter NBC1 (SLC4A4) mRNA,
alternatively spliced product, complete cds.
ACCESSION AF157492
VERSION AF157492.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3771)
AUTHORS Pushkin,A., Abuladze N. and Kurtz I.
TITLE Homo sapiens sodium bicarbonate cotransporter NBC1 splice variant
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 3771)
AUTHORS Pushkin,A., Abuladze N. and Kurtz I.
TITLE Direct Submission
JOURNAL Submitted (08-JUN-1999) Medicine, UCLA, 10833 Le Conte Ave, Los
Angeles, CA 90095, USA
FEATURES Location/Qualifiers
source 1..3771
/db_xref="H-InvDB:HIT000071997"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="4"
/map="4q21"
/tissue_type="skeletal muscle"
gene 1..3771
/gene="SLC4A4"
/note="NBC1"
CDS 77..3064
/gene="SLC4A4"
/note="alternatively spliced product"
/codon_start=1
/product="sodium bicarbonate cotransporter NBC1"
/protein_id="AAF80343.1"
/translation="MEDEAVLDRGASFLKHVCDEEEVEGHHTIYIGVHVPKSYRRRRR
HKRKTGHKEKKEKERISENYSDKSDIENADESSSSILKPLISPAAERIRFILGEEDDS
PAPPQLFTELDELLAVDGQEMEWKETARWIKFEEKVEQGGERWSKPHVATLSLHSLFE
LRTCMEKGSIMLDREASSLPQLVEMIVDHQIETGLLKPELKDKVTYTLLRKHRHQTKK
SNLRSLADIGKTVSSASRMFTNPDNGSPAMTHRNLTSSSLNDISDKPEKDQLKNKFMK
KLPRDAEASNVLVGEVDFLDTPFIAFVRLQQAVMLGALTEVPVPTRFLFILLGPKGKA
KSYHEIGRAIATLMSDEVFHDIAYKAKDRHDLIAGIDEFLDEVIVLPPGEWDPAIRIE
PPKSLPSSDKRKNMYSGGENVQMNGDTPHDGGHGGGGHGDCEELQRTGRFCGGLIKDI
KRKAPFFASDFYDALNIQALSAILFIYLATVTNAITFGGLLGDATDNMQGVLESFLGT
AVSGAIFCLFAGQPLTILSSTGPVLVFERLLFNFSKDNNFDYLEFRLWIGLWSAFLCL
ILVATDASFLVQYFTRFTEEGFSSLISFIFIYDAFKKMIKLADYYPINSNFKVGYNTL
FSCTCVPPDPANISISNDTTLAPEYLPTMSSTDMYHNTTFDWAFLSKKECSKYGGNLV
GNNCNFVPDITLMSFILFLGTYTSSMALKKFKTSPYFPTTARKLISDFAIILSILIFC
VIDALVGVDTPKLIVPSEFKPTSPNRGWFVPPFGENPWWVCLAAAIPALLVTILIFMD
QQITAVIVNRKEHKLKFIPMPVLYGVFLYMGVASLNGVQFMDRLKLLLMPLKHQPDFI
YLRHVPLRRVHLFTFLQVLCLALLWILKSTVAAIIFPVMILALVAVRKGMDYLFSQHD
LSFLDDVIPEKDKKKKEDEKKKKKKKGSLDSDNDDSDCPYSEKVPSIKIPMDIMEQQP
FLSDSKPSDRERSPTFLERHTSC"
BASE COUNT 1032 a 850 c 845 g 1044 t
ORIGIN
1 ggcagtggca gtggccgctg cagccccaca ctccgccgcc aaactggagg agcgacggaa
61 gccagacccc aggaggatgg aggatgaagc tgtcctggac agaggggctt ccttcctcaa
121 gcatgtgtgt gatgaagaag aagtagaagg ccaccatacc atttacatcg gagtccatgt
181 gccgaagagt tacaggagaa ggagacgtca caagagaaag acagggcaca aagaaaagaa
241 ggaaaaggag agaatctctg agaactactc tgacaaatca gatattgaaa atgctgatga
301 atccagcagc agcatcctaa aacctctcat ctctcctgct gcagaacgca tccgattcat
361 cttgggagag gaggatgaca gcccagctcc ccctcagctc ttcacggaac tggatgagct
421 gctggccgtg gatgggcagg agatggagtg gaaggaaaca gccaggtgga tcaagtttga
481 agaaaaagtg gaacagggtg gggaaagatg gagcaagccc catgtggcca cattgtccct
541 tcatagttta tttgagctga ggacatgtat ggagaaagga tccatcatgc ttgatcggga
601 ggcttcttct ctcccacagt tggtggagat gattgttgac catcagattg agacaggcct
661 attgaaacct gaacttaagg ataaggtgac ctatactttg ctccggaagc accggcatca
721 aaccaagaaa tccaaccttc ggtccctggc tgacattggg aagacagtct ccagtgcaag
781 taggatgttt accaaccctg ataatggtag cccagccatg acccatagga atctgacttc
841 ctccagtctg aatgacattt ctgataaacc ggagaaggac cagctgaaga ataagttcat
901 gaaaaaattg ccacgtgatg cagaagcttc caacgtgctt gttggggagg ttgacttttt
961 ggatactcct ttcattgcct ttgttaggct acagcaggct gtcatgctgg gtgccctgac
1021 tgaagttcct gtgcccacaa ggttcttgtt cattctctta ggtcctaagg ggaaagccaa
1081 gtcctaccac gagattggca gagccattgc caccctgatg tctgatgagg tgttccatga
1141 cattgcttat aaagcaaaag acaggcacga cctgattgct ggtattgatg agttcctaga
1201 tgaagtcatc gtccttccac ctggggaatg ggatccagca attaggatag agcctcctaa
1261 gagtcttcca tcctctgaca aaagaaagaa tatgtactca ggtggagaga atgttcagat
1321 gaatggggat acgccccatg atggaggtca cggaggagga ggacatgggg attgtgaaga
1381 attgcagcga actggacggt tctgtggtgg actaattaaa gacataaaga ggaaagcgcc
1441 attttttgcc agtgattttt atgatgcttt aaatattcaa gctctttcgg caattctctt
1501 catttatctg gcaactgtaa ctaatgctat cacttttgga ggactgcttg gggatgccac
1561 tgacaacatg cagggcgtgt tggagagttt cctgggcact gctgtctctg gagccatctt
1621 ttgccttttt gctggtcaac cactcactat tctgagcagc accggacctg tcctagtttt
1681 tgagaggctt ctatttaatt tcagcaagga caataatttt gactatttgg agtttcgcct
1741 ttggattggc ctgtggtccg ccttcctatg tctcattttg gtagccactg atgccagctt
1801 cttggttcaa tacttcacac gtttcacgga ggagggcttt tcctctctga ttagcttcat
1861 ctttatctat gatgctttca agaagatgat caagcttgca gattactacc ccatcaactc
1921 caacttcaaa gtgggctaca acactctctt ttcctgtacc tgtgtgccac ctgacccagc
1981 taatatctca atatctaatg acaccacact ggccccagag tatttgccaa ctatgtcttc
2041 tactgacatg taccataata ctacctttga ctgggcattt ttgtcgaaga aggagtgttc
2101 aaaatacgga ggaaacctcg tcgggaacaa ctgtaatttt gttcctgata tcacactcat
2161 gtcttttatc ctcttcttgg gaacctacac ctcttccatg gctctgaaaa aattcaaaac
2221 tagtccttat tttccaacca cagcaagaaa actgatcagt gattttgcca ttatcttgtc
2281 cattctcatc ttttgtgtaa tagatgccct agtaggcgtg gacaccccaa aactaattgt
2341 gccaagtgag ttcaagccaa caagtccaaa ccgaggttgg ttcgttccac cgtttggaga
2401 aaacccctgg tgggtgtgcc ttgctgctgc tatcccggct ttgttggtca ctatactgat
2461 tttcatggac caacaaatta cagctgtgat tgtaaacagg aaagaacata aactcaagtt
2521 tatacccatg cctgtactct atggtgtgtt cctgtatatg ggagtagcat cccttaatgg
2581 tgtgcagttc atggatcgtc tgaagctgct tctgatgcct ctgaagcatc agcctgactt
2641 catctacctg cgtcatgttc ctctgcgcag agtccacctg ttcactttcc tgcaggtgtt
2701 gtgtctggcc ctgctttgga tcctcaagtc aacggtggct gctatcattt ttccagtaat
2761 gatcttggca cttgtagctg tcagaaaagg catggactac ctcttctccc agcatgacct
2821 cagcttcctg gatgatgtca ttccagaaaa ggacaagaaa aagaaggagg atgagaagaa
2881 aaagaaaaag aagaagggaa gtctggacag tgacaatgat gattctgact gcccatactc
2941 agaaaaagtt ccaagtatta aaattccaat ggacatcatg gaacagcaac ctttcctaag
3001 cgatagcaaa ccttctgaca gagaaagatc accaacattc cttgaacgcc acacatcatg
3061 ctgataaaat tcctttcctt cagtcactcg gtatgccaag tcctcctaga actccagtaa
3121 aagttgtgcc tcaaattaga atagaacttg aacctgaaga caatgattat ttctggagga
3181 gcaagggaac agaaactaca ttgtaacctg tttgtctttc ttaaaactga catttgttgt
3241 taatgtcatt tgtttttgtt tggctgtttg tttatttttt aacttttatt tcgtctcagt
3301 ttttggtcac aggccaaata atacagcgct ctctctgctt ctctcttgca tagatacaat
3361 caagacaata gtgcaccgtt ccttaaaaac agcatctgag gaatccccct tttgttctta
3421 aactttcaga tgtgtccttt gataaccaaa ttctgtcact caagacacag acacccacag
3481 accctgtcct ttgcctctat taagcagagg atggaagtat taaggatttt gtaacacctt
3541 ttatgaaaat gttgaaggaa cttaaaactt tagctttgga gctgtgctta ctggcttgtc
3601 tttgtctggt agaacaaacc ttgacctcca gacagagtcc cttctcactt atagagctct
3661 ccaggactgg aaaaagtgct gctattttaa cttgctcttg cttgtaaatc ctaatcttag
3721 agttatcaaa agaagaaaaa actgaaggta ctttactccc tatagagaaa c
//