LOCUS AF155908 2152 bp mRNA linear HUM 27-DEC-1999
DEFINITION Homo sapiens cardiovascular heat shock protein mRNA, complete cds.
ACCESSION AF155908
VERSION AF155908.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2152)
AUTHORS Krief,S., Faivre,J.F., Robert,P., Le Douarin,B.,
Brument-Larignon,N., Lefrere,I., Bouzyk,M.M., Anderson,K.M.,
Greller,L.D., Tobin,F.L., Souchet,M. and Bril,A.
TITLE Identification and characterization of cvHsp. A novel human small
stress protein selectively expressed in cardiovascular and
insulin-sensitive tissues
JOURNAL J. Biol. Chem. 274 (51), 36592-36600 (1999)
PUBMED 10593960
REFERENCE 2 (bases 1 to 2152)
AUTHORS Krief,S., Faivre,J.-F., Robert,P., Le Douarin,B.,
Brument-Larignon,N., Lefrere,I., Bouzyk,M.M., Anderson,K.A.,
Greller,L.D., Tobin,F.L., Souchet,M. and Bril,A.
TITLE Direct Submission
JOURNAL Submitted (02-JUN-1999) Cardiovascular Pharmacolgy, SmithKline
Beecham, 4 rue du Chesnay-Beauregard, Saint-Gregoire 35760, France
FEATURES Location/Qualifiers
source 1..2152
/db_xref="H-InvDB:HIT000071958"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="1"
/map="1p36.23-p34.3 between markers D1S434 and D1S507"
CDS 75..587
/note="25 kDa heat stress protein; cvHsp; preferentially
expressed in cardiovascular and insulin-sensitive tissues;
interacts with C-terminal domain of alpha-filamin or
actin-binding-280, ABP-280"
/codon_start=1
/product="cardiovascular heat shock protein"
/protein_id="AAF20022.1"
/translation="MSHRTSSTFRAERSFHSSSSSSSSSTSSSASRALPAQDPPMEKA
LSMFSDDFGSFMRPHSEPLAFPARPGGAGNIKTLGDAYEFAVDVRDFSPEDIIVTTSN
NHIEVRAEKLAADGTVMNTFAHKCQLPEDVDPTSVTSALREDGSLTIRARRHPHTEHV
QQTFRTEIKI"
regulatory 2115..2120
/regulatory_class="polyA_signal_sequence"
BASE COUNT 459 a 700 c 569 g 424 t
ORIGIN
1 ggcacgaggc ctgcgcccac accctctcct gtccagccct cgcccgcctg ggcagggccc
61 ggcgccgtcc gtggatgagc cacagaacct cttccacctt ccgagcggag agaagtttcc
121 attcctcttc ttcttcctcc tcctcttcca cctcctcctc ggcctcccgt gctctcccgg
181 cccaggaccc gcccatggag aaggccctga gcatgttttc cgatgacttt ggcagcttca
241 tgcggcccca ctcggagccc ctggccttcc cagcccgccc cggtggggca ggcaacatca
301 agaccctagg agacgcctat gagtttgcgg tggacgtgag agacttctca cctgaagaca
361 tcattgtcac cacctccaac aaccacatcg aggtgcgggc tgagaagctg gcggctgacg
421 gcactgtcat gaacaccttc gctcacaagt gccagctgcc ggaggacgtg gacccgacgt
481 cggtgacctc ggctctgcgg gaggacggca gcctcactat ccgggcacgg cgtcacccgc
541 atacagaaca cgtccagcag accttccgga cggagatcaa aatctgagtg cctctccctt
601 ccctttccct gtccccccgc cccacgcctg ccagcaaagc ctcgctaacc ccattacaac
661 agctccagga catctcagcc caggttctag cccccacgca cccagacccc aggtggacca
721 tcctcccaaa ctagggccct ccactctatc cagggcaggc cagggactcc ctggcctgac
781 acatgatgcc cagatttcag atttggcctc cgtcacttaa tccagagtac aggggctggg
841 gtcagggaag gaagatctaa agaacccact gtgggtcagg ggaatgggac cagcaggaca
901 tatgggcaag ctctgcagga cagacagaca gacaaaccct ctgatctatg aagtctctgc
961 agggcaaggg gaccagggac ctggaaccct cttggccaag gggagtggga gggacagagg
1021 gaaggtcaca ggcaagggtg cctatctaag tggaactaat tgcccgaggg ctcagcaagg
1081 ccaagaggag acagccgtga cggtaaactt cccctctacc agcctccaag ccccacgcca
1141 gcgagcaggc tgcctgccca ccccgtgccc ccagccagct ggctgtgcca gggcagagcc
1201 atgccacatc tgtatataga tggggttttt ccaatacagc tggttcgtga taaactgcat
1261 gaaactcctg ccgtcctgcg cctgctgggg cctccaggca aggccaagtg gggttggggg
1321 tggggctggt ccttctccct cccacaggcc tgtgttcttg gggctgctcc catgcagaca
1381 ggatcaccta acagagatgg aagccagggc atggatgggg ctttgggtcc tcgaggttgg
1441 accccagctt cttgccacct tcccctccgg gcagtcagct ctccatccat ccccctcttt
1501 aatctatgaa tctataggct cggtgtgtgt aacacacaca cccctatcgt tgtccttcaa
1561 atactcagca ttaccattgg ttgaggccaa attcagagct ttctcaaatc agatttacaa
1621 tctccatttt cattaacggg gaaacatccc cgagccactg agtgctgtgc tttgtcactg
1681 aaggttagat ctgaacccag ggtgtcaaca gctgctctca actccccacc tctgggcact
1741 gaggagtatt tcccctcatt ctacctctct aaggctatgc accctcccca cgtcttccag
1801 ctgggggatg gggggagtca taggaaaagc ccccatctcc catctgggat agggaccttc
1861 catcagcctt aaccctggga aatgcctgct gcccccaatg actcttggtt tcgtctccca
1921 catacagaag cagggtggag gggaagggtg ggtctcagtt agcaggggtc cccagggcaa
1981 gtcagcctcc tccctccatg cctctctggt cagtgtgcct tagggtggcc tctcactccc
2041 accactctgg gccccttggg ggaggactgg ggagggggcc gtgggagagc cctgacgctg
2101 gaacctgtat acacaataaa ggacagtctc acagaaaaaa aaaaaaaaaa aa
//