LOCUS AF155582 1794 bp mRNA linear HUM 03-JAN-2002
DEFINITION Homo sapiens core1 UDP-galactose:N-acetylgalactosamine-alpha-R beta
1,3-galactosyltransferase (C1GALT1) mRNA, complete cds.
ACCESSION AF155582
VERSION AF155582.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1794)
AUTHORS Ju,T., Brewer,K., D'Souza,A., Cummings,R.D. and Canfield,W.M.
TITLE Cloning and Expression of Human Core 1 beta
1,3-Galactosyltransferase
JOURNAL J. Biol. Chem. 277 (1), 178-186 (2002)
PUBMED 11677243
REFERENCE 2 (bases 1 to 1794)
AUTHORS Ju,T.Z., Cummings,R.D. and Canfield,W.M.
TITLE Cloning and characterization of human core1
UDP-galactose:N-acetylgalactosamine-alpha-R beta
1,3-galactosyltransferase (Core1 beta3-Gal-T) cDNA sequence
JOURNAL Unpublished
REFERENCE 3 (bases 1 to 1794)
AUTHORS Ju,T.Z., Cummings,R.D. and Canfield,W.M.
TITLE Direct Submission
JOURNAL Submitted (01-JUN-1999) Department of Medicine, The University of
Oklahoma, Health Science Center, 975 N.E. 10th Street, Biomedical
Research Center, Room 411, Oklahoma City, OK 73104, USA
FEATURES Location/Qualifiers
source 1..1794
/db_xref="H-InvDB:HIT000071948"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="7"
/map="7p14-p13"
gene 1..1794
/gene="C1GALT1"
CDS 63..1154
/gene="C1GALT1"
/EC_number="2.4.1.122"
/function="responsible for the synthesis of core1
structure of O-glycans"
/note="core1 beta3-Gal-T"
/codon_start=1
/product="core1
UDP-galactose:N-acetylgalactosamine-alpha-R beta
1,3-galactosyltransferase"
/protein_id="AAF81981.1"
/translation="MASKSWLNFLTFLCGSAIGFLLCSQLFSILLGEKVDTQPNVLHN
DPHARHSDDNGQNHLEGQMNFNADSSQHKDENTDIAENLYQKVRILCWVMTGPQNLEK
KAKHVKATWAQRCNKVLFMSSEENKDFPAVGLKTKEGRDQLYWKTIKAFQYVHEHYLE
DADWFLKADDDTYVILDNLRWLLSKYDPEEPIYFGRRFKPYVKQGYMSGGAGYVLSKE
ALKRFVDAFKTDKCTHSSSIEDLALGRCMEIMNVEAGDSRDTIGKETFHPFVPEHHLI
KGYLPRTFWYWNYNYYPPVEGPGCCSDLAVSFHYVDSTTMYELEYLVYHLRPYGYLYR
YQPTLPERILKEISQANKNEDTKVKLGNP"
misc_feature 75..158
/gene="C1GALT1"
/inference="non-experimental evidence, no additional
details recorded"
/note="Region: non-cleavable transmembrane signal"
BASE COUNT 624 a 300 c 334 g 536 t
ORIGIN
1 tacagctttg attttataac atcctgctaa tttttgttct tacagaaata cactttcggg
61 aaatggcctc taaatcctgg ctgaattttt taaccttcct ctgtggatca gcaataggat
121 ttcttttatg ttctcagcta tttagtattt tgttgggaga aaaggttgac acccagccta
181 atgttcttca taatgatcct catgcaaggc attcagatga taatggacag aatcatctag
241 aaggacaaat gaacttcaat gcagattcta gccaacataa agatgagaac acagacattg
301 ctgaaaacct ctatcagaaa gttagaattc tttgctgggt tatgaccggc cctcaaaacc
361 tagagaaaaa ggccaaacac gtcaaagcta cttgggccca gcgttgtaac aaagtgttgt
421 ttatgagttc agaagaaaat aaagacttcc ctgctgtggg actgaaaacc aaagaaggca
481 gagatcaact atactggaaa acaattaaag cttttcagta tgttcatgaa cattatttag
541 aagatgctga ttggtttttg aaagcagatg atgacacgta tgtcatacta gacaatttga
601 ggtggcttct ttcaaaatac gaccctgaag aacccattta ctttgggaga agatttaagc
661 cttatgtaaa gcagggctac atgagtggag gagcaggata tgtactaagc aaagaagcct
721 tgaaaagatt tgttgatgca tttaaaacag acaagtgtac acatagttcc tccattgaag
781 acttagcact ggggagatgc atggaaatta tgaatgtaga agcaggagat tccagagata
841 ccattggaaa agaaactttt catccctttg tgccagaaca ccatttaatt aaaggttatc
901 tacctagaac gttttggtac tggaattaca actattatcc tcctgtagag ggtcctggtt
961 gctgctctga tcttgcagtt tcttttcact atgttgattc tacaaccatg tatgagttag
1021 aatacctcgt ttatcatctt cgtccatatg gttatttata cagatatcaa cctaccttac
1081 ctgaacgtat actaaaggaa attagtcaag caaacaaaaa tgaagataca aaagtgaagt
1141 taggaaatcc ttgaaagaaa atcatgaatg aacaaaggta atatgtctag cactgcactg
1201 aaaaaggact tctgcatttc tgacatagaa cactggaatc ccagtgagga attctaagtg
1261 aacattcctt atagaaacct ttcacatgaa tgactataaa ctgaagcttt aaatgagctg
1321 tgaagtgtgt taaaatgtgt tttgatacag taatatataa atatgtctat atatatgagg
1381 aacttgtgtt ttttaaatgg tggccaggta gaggaactag aaaagagatt ttgttgcctg
1441 ttttctgacc atctgtgtta ttgtcactga gaaactaaaa tagtaaattt actaaaacta
1501 cactgcacca tgttagtaat aaacagatct gccttaaaga aaagaaaatt ttagaaagaa
1561 atattgttgc tcagtgttgt taatatagct caagaattga gtttatattt gcagtatgct
1621 ataaatgata cccccctacc acacccacac acacagtttt tgtctaatga aaatgttgct
1681 gtgattattt ataattggta gtatttcttc cagaagaagc taaaataaga ctggcactta
1741 ccctgaagtg cattaataaa accacacttt aaaattaaaa aaaaaaaaaa aaaa
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