LOCUS AF155330 1669 bp mRNA linear HUM 21-JUN-1999
DEFINITION Homo sapiens putative membrane protein (TIM22) mRNA, complete cds.
ACCESSION AF155330
VERSION AF155330.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1669)
AUTHORS Bauer,M.F., Brunner,M., Neupert W., Gerbitz K.-D. and Hofmann,S.
TITLE Cloning and mapping of human Tim22, homologous to S.cerevisiae
Tim22, a membrane-integrated component of the Tim22-54 machinery
for the import of mitochondrial carrier proteins
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 1669)
AUTHORS Bauer,M.F., Brunner,M., Neupert W., Gerbitz K.-D. and Hofmann,S.
TITLE Direct Submission
JOURNAL Submitted (31-MAY-1999) Institute of Clinical Chemistry, Molecular
Diagnostics and Mitochondrial Genetics, KH Munich-Schwabing,
Koelner Platz 1, Munich 80804, Germany
FEATURES Location/Qualifiers
source 1..1669
/db_xref="H-InvDB:HIT000071942"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="17"
/map="17p13"
gene 1..1669
/gene="TIM22"
CDS 6..590
/gene="TIM22"
/note="component of the mitochondrial inner membrane
putatively involved in mitochondrial carrier import;
similar to yeast Tim22; similar to the membrane integrated
components of the Tim17-23 machinery for the import of
matrix-targeted preproteins"
/codon_start=1
/product="putative membrane protein"
/protein_id="AAD40106.1"
/translation="MAAAAPNAGGSAPETAGSAEAPLQYSLLLQYLVGDKRQPRLLEP
GSLGGIPSPAKSEEQKMIEKAMESCAFKAALACVGGFVLGGAFGVFTAGIDTNVGFDP
KDPYRTPTAKEVLKEHGQRGMSYAKNFAIVGAMFSCTWCLIESYRGTSDLKNSVISGC
ITGGAYWFRAGLKAGALLCGGFAAFSAAIDYYLR"
BASE COUNT 363 a 429 c 461 g 414 t
ORIGIN
1 ctgtcatggc ggcggccgcc cccaatgccg gaggctcggc ccctgagaca gcgggttccg
61 ccgaagctcc gctgcagtac agcctgctcc tgcagtacct ggtgggtgac aagcgtcagc
121 cccggctcct ggagcctggg agcctgggcg ggatcccaag tccagccaag agtgaggagc
181 agaagatgat cgagaaggcg atggaaagct gcgctttcaa ggctgcgctg gcctgcgtgg
241 gaggatttgt cttaggaggt gcatttgggg tgtttaccgc tggcatcgat accaacgtgg
301 gctttgaccc taaggatcct taccgtacac cgactgcaaa agaagtgctg aaagaacatg
361 ggcagagagg aatgtcctat gccaaaaatt tcgccattgt gggagccatg ttttcttgta
421 cctggtgttt gatagaatct taccgnggaa catcagactt gaagaacagt gtcatcagtg
481 gctgcatcac gggaggagcc tattggttca gagctggctt aaaggctggg gcccttttgt
541 gtggaggttt tgctgctttc tctgctgcga ttgattatta cctccggtga gagtaattgc
601 ctgcagggaa ggatgatgcc agccccggat ccgggctgct ctctggagga cagtttctgt
661 accacaccag ggccttgctt cagggcctga agacattcat tttccctcat gtcgttggta
721 ttctgaggga gctgcctggc ttctctgcct ccagcctttg gggtagccac actttgctgc
781 tcctggactc cagccagcct tcacagagga cgtcccgtgc cagattctct cacagcagat
841 cgggagacag gatgttgaca tataggaatt cagctccaca aagcttcagg cctgaccaca
901 gctggccctc taggttgttt ggtgttgtgg gcacagaggt gacagtgtct ctgcaggcac
961 tcaggaagct gttctacctt ggaactccat gcaactatcc gtctcgaata ccagggcagg
1021 gcaaggcgga ctgatgccgt ccaaccaatt atctcacttg ttttgtgttc tgtcatcctt
1081 gttttttttt taaaaataca ctcccctccc ccaccgccac acaccttaca gttcaaaagg
1141 ttggtttatt tgtattttat tttcaaattc cctattccaa aaatagtgcc gggtggccca
1201 aagataacat ctgaagggaa agaatgagaa agctcccagg gaagyggggg atggggcgct
1261 gaggcagggt tgttagagga ctgtgtcatc ctcaccaagc tcattacatc tgccagggcc
1321 tgcctcaaga agcccagccc agccttttcc tgggatgcag tgaaatccca tccatgaact
1381 cgatgggccc ctcctgtgcc ggccgagagg cacacactgc cttcacgacg tgactgctgg
1441 acctggccga gcttgaggcc acatgtgaag ggtcctgctg tggtcatctt ggtgactcgg
1501 tcacagcagc tactggccaa gatcagacgt cgctgagggg ctgttcacca ccatcctcgt
1561 tctccagggt caaggaagtg ttttaacatg tcgtgttttc gacttgacct tgtggtattt
1621 ttcttggcct agttgtgtgc catggatatt taaaaaaaaa aaaaaaaaa
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